JPS6445374A - Water-soluble tetrazolium compound and determination of reducing substance using said compound - Google Patents

Water-soluble tetrazolium compound and determination of reducing substance using said compound

Info

Publication number
JPS6445374A
JPS6445374A JP20216487A JP20216487A JPS6445374A JP S6445374 A JPS6445374 A JP S6445374A JP 20216487 A JP20216487 A JP 20216487A JP 20216487 A JP20216487 A JP 20216487A JP S6445374 A JPS6445374 A JP S6445374A
Authority
JP
Japan
Prior art keywords
compound
lower alkyl
determination
halogen
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP20216487A
Other languages
Japanese (ja)
Other versions
JP2590124B2 (en
Inventor
Hiroshi Nishii
Yoshifumi Watatsu
Masamitsu Takahashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KOKUSAI SHAKU KK
KOKUSAI SHIYAKU KK
Original Assignee
KOKUSAI SHAKU KK
KOKUSAI SHIYAKU KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KOKUSAI SHAKU KK, KOKUSAI SHIYAKU KK filed Critical KOKUSAI SHAKU KK
Priority to JP20216487A priority Critical patent/JP2590124B2/en
Publication of JPS6445374A publication Critical patent/JPS6445374A/en
Application granted granted Critical
Publication of JP2590124B2 publication Critical patent/JP2590124B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Abstract

NEW MATERIAL:The water-soluble tetrazolium compound of formula I (R1 and R2 are H, lower alkyl, lower alkoxy, halogen, cyano or nitro; R3 is lower alkyl, lower alkoxy or halogen; R4 is H or lower alkyl; R5 is lower alkylene; Y is H, lower alkyl, lower alkoxy, halogen or nitro). EXAMPLE:The compound of formula II. USE:The quantity of a reducing substance such as reduced nicotinamide-adenine dinucleotide or reduced nicotinamide-adenine dinucleotide phosphate can be determined by the use of the compound. The activity of reductase and dehydrogenase can be determined from the quantity of the above substances and the compound is useful for the determination of biotic component and an additive in a food. PREPARATION:The compound of formula I can be produced e.g. by condensing m-nitrobenzenesulfonyl chloride with 2-aminoethanesulfonic acid and subjecting the condensation product to several processes such as reduction.
JP20216487A 1987-08-12 1987-08-12 Water-soluble tetrazolium compound and method for measuring reducing substance using the compound Expired - Lifetime JP2590124B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP20216487A JP2590124B2 (en) 1987-08-12 1987-08-12 Water-soluble tetrazolium compound and method for measuring reducing substance using the compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP20216487A JP2590124B2 (en) 1987-08-12 1987-08-12 Water-soluble tetrazolium compound and method for measuring reducing substance using the compound

Publications (2)

Publication Number Publication Date
JPS6445374A true JPS6445374A (en) 1989-02-17
JP2590124B2 JP2590124B2 (en) 1997-03-12

Family

ID=16453019

Family Applications (1)

Application Number Title Priority Date Filing Date
JP20216487A Expired - Lifetime JP2590124B2 (en) 1987-08-12 1987-08-12 Water-soluble tetrazolium compound and method for measuring reducing substance using the compound

Country Status (1)

Country Link
JP (1) JP2590124B2 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06253899A (en) * 1993-03-02 1994-09-13 Toyobo Co Ltd Reagent composition for measurement of urea nitrogen
US5932598A (en) * 1996-04-12 1999-08-03 G. D. Searle & Co. Prodrugs of benzenesulfonamide-containing COX-2 inhibitors
US6613790B2 (en) 2001-04-17 2003-09-02 Pharmacia Corporation Prodrugs of COX-2 inhibitors
US6673818B2 (en) 2001-04-20 2004-01-06 Pharmacia Corporation Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation
WO2011132480A1 (en) * 2010-04-19 2011-10-27 Jnc株式会社 Tetrazolium compound for detecting microorganisms, reagent for detecting microorganisms and method for detecting microorganisms

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06253899A (en) * 1993-03-02 1994-09-13 Toyobo Co Ltd Reagent composition for measurement of urea nitrogen
US5932598A (en) * 1996-04-12 1999-08-03 G. D. Searle & Co. Prodrugs of benzenesulfonamide-containing COX-2 inhibitors
US6436967B1 (en) 1996-04-12 2002-08-20 Pharmacia Corporation Process for preparing prodrugs of benzenesulfonamide-containing cox-2 inhibitors
US6815460B2 (en) 1996-04-12 2004-11-09 Pharmacia Corporation Process for preparing prodrugs of benzenesulfonamide-containing cox-2 inhibitors
BG64531B1 (en) * 1996-04-12 2005-06-30 G.D.Searle & Co Substituted benzenesulphonamide derivatives as precursors of cox-2 inhibitors
US6613790B2 (en) 2001-04-17 2003-09-02 Pharmacia Corporation Prodrugs of COX-2 inhibitors
US6673818B2 (en) 2001-04-20 2004-01-06 Pharmacia Corporation Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation
US6699884B2 (en) 2001-04-20 2004-03-02 Pharmacia Corporation Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation
WO2011132480A1 (en) * 2010-04-19 2011-10-27 Jnc株式会社 Tetrazolium compound for detecting microorganisms, reagent for detecting microorganisms and method for detecting microorganisms
JP5765335B2 (en) * 2010-04-19 2015-08-19 Jnc株式会社 Microorganism detection tetrazolium compound, microorganism detection reagent and microorganism detection method
US11022556B2 (en) 2010-04-19 2021-06-01 Jnc Corporation Tetrazolium compound for detecting microorganisms, reagent for detecting microorganisms and method for detecting microorganisms

Also Published As

Publication number Publication date
JP2590124B2 (en) 1997-03-12

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