DK16293A - Ruthenium og osmium-komplekser til brug ved kvalitativ og kvantitativ elektrokemiluminiscerende analysering af multikomponentvaesker samt biologiske forbindelser indeholdende disse komplekser - Google Patents

Ruthenium og osmium-komplekser til brug ved kvalitativ og kvantitativ elektrokemiluminiscerende analysering af multikomponentvaesker samt biologiske forbindelser indeholdende disse komplekser

Info

Publication number
DK16293A
DK16293A DK016293A DK16293A DK16293A DK 16293 A DK16293 A DK 16293A DK 016293 A DK016293 A DK 016293A DK 16293 A DK16293 A DK 16293A DK 16293 A DK16293 A DK 16293A
Authority
DK
Denmark
Prior art keywords
electrochemiluminizing
complexs
ruthenium
qualitative
quantitative
Prior art date
Application number
DK016293A
Other languages
English (en)
Other versions
DK16293D0 (da
DK173025B1 (da
Inventor
Richard J Massey
Michael J Powell
Paul A Mied
Peter Feng
Leopoldo Della Ciana
Walter J Dressick
Mohindar S Poonian
Original Assignee
Igen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Igen Inc filed Critical Igen Inc
Publication of DK16293A publication Critical patent/DK16293A/da
Publication of DK16293D0 publication Critical patent/DK16293D0/da
Application granted granted Critical
Publication of DK173025B1 publication Critical patent/DK173025B1/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/002—Osmium compounds
    • C07F15/0026—Osmium compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds
    • C07F15/0053—Ruthenium compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/30—Electrochemically active labels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Reproductive Health (AREA)
  • Toxicology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Luminescent Compositions (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK199300162A 1986-04-30 1993-02-12 Ruthenium og osmium-komplekser til brug ved kvalitativ og kvantitativ elektrokemiluminiscerende analysering af multikompone DK173025B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US85835486A 1986-04-30 1986-04-30
US85835486 1986-04-30
PCT/US1987/000987 WO1987006706A1 (en) 1986-04-30 1987-04-30 Electrochemiluminescent assays
US8700987 1987-04-30

Publications (3)

Publication Number Publication Date
DK16293A true DK16293A (da) 1993-02-12
DK16293D0 DK16293D0 (da) 1993-02-12
DK173025B1 DK173025B1 (da) 1999-11-15

Family

ID=25328109

Family Applications (1)

Application Number Title Priority Date Filing Date
DK199300162A DK173025B1 (da) 1986-04-30 1993-02-12 Ruthenium og osmium-komplekser til brug ved kvalitativ og kvantitativ elektrokemiluminiscerende analysering af multikompone

Country Status (12)

Country Link
EP (3) EP0265519B1 (da)
JP (6) JPH0737464B2 (da)
KR (1) KR960016340B1 (da)
AT (2) ATE212030T1 (da)
AU (2) AU644150B2 (da)
CA (1) CA1339465C (da)
DE (2) DE3751516T2 (da)
DK (1) DK173025B1 (da)
FI (1) FI102017B1 (da)
IL (1) IL82411A0 (da)
NO (1) NO176071C (da)
WO (1) WO1987006706A1 (da)

Families Citing this family (140)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6165729A (en) * 1986-04-30 2000-12-26 Hyperion Catalysis International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US5770459A (en) * 1986-04-30 1998-06-23 Igen International, Inc. Methods and apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence detection
US6881536B1 (en) * 1986-04-30 2005-04-19 Bioveris Corporation Particle based electrochemiluminescent assays
US6271041B1 (en) * 1986-04-30 2001-08-07 Igen International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US6451225B1 (en) 1986-04-30 2002-09-17 Igen International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US5635347A (en) * 1986-04-30 1997-06-03 Igen, Inc. Rapid assays for amplification products
US6881589B1 (en) 1987-04-30 2005-04-19 Bioveris Corporation Electrochemiluminescent localizable complexes for assay compositions
US5935779A (en) * 1988-11-03 1999-08-10 Igen International Inc. Methods for improved particle electrochemiluminescence assay
US6702986B1 (en) 1988-04-29 2004-03-09 Igen International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
JPH076913B2 (ja) * 1988-11-03 1995-01-30 イゲン，インコーポレーテッド アミン誘導還元剤を利用する電気化学発光反応
US5746974A (en) * 1988-11-03 1998-05-05 Igen International, Inc. Apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence and chemiluminescence detection
US5962218A (en) * 1988-11-03 1999-10-05 Igen International Inc. Methods and apparatus for improved luminescence assays
US5705402A (en) * 1988-11-03 1998-01-06 Igen International, Inc. Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets
DE68928994T2 (de) * 1988-11-03 1999-12-16 Igen International, Inc. Elektrochemilumineszente testverfahren
JPH0363571A (ja) * 1989-08-02 1991-03-19 Chisso Corp 大腸菌群の検査キット
IL100867A (en) * 1991-02-06 1995-12-08 Igen Inc Method and apparatus for improved luminescence assays
ZA92803B (en) 1991-02-06 1992-11-25 Igen Inc Method and apparatus for magnetic microparticulate based luminescene asay including plurality of magnets
IL100866A (en) * 1991-02-06 1995-10-31 Igen Inc Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets
KR100212178B1 (ko) * 1991-07-10 1999-08-02 리차드 제이 마세이 입자농도 및 화학발광 검출을 이용한 개선된 발광 검정 장치 및 방법
DE69231124T2 (de) * 1991-11-15 2001-02-15 Igen International, Inc. Schnelle bestimmungsverfahren für amplifikationsprodukte
ZA929351B (en) * 1991-12-11 1993-06-04 Igen Inc Electrochemiluminescent label for DNA assays.
FR2699170B1 (fr) * 1992-12-15 1995-07-28 Asulab Sa Complexes d'un métal de transition à ligands 2,2'-bipyridine substitués par au moins un radical ammonium alkyle, leur procédé de fabrication et leur application comme médiateur redox.
US5541113A (en) * 1993-09-22 1996-07-30 Beckman Instruments, Inc. Method for detecting an analyte using an electrochemical luminescent transition metal label
DE59507438D1 (de) * 1994-07-25 2000-01-20 Roche Diagnostics Gmbh Hydrophile metallkomplexe
NZ306051A (en) 1995-03-10 1999-11-29 Meso Scale Technologies Llc Testing using electrochemiluminescence
US6319670B1 (en) 1995-05-09 2001-11-20 Meso Scale Technology Llp Methods and apparatus for improved luminescence assays using microparticles
ES2285713T3 (es) 1995-06-07 2007-11-16 Bioveris Corporation Enzimoinmunoanalisis electroquimioluminiscente.
JP3574457B2 (ja) * 1995-09-12 2004-10-06 エーザイ株式会社 電気化学発光検出方法と装置
US7192450B2 (en) 2003-05-21 2007-03-20 Dexcom, Inc. Porous membranes for use with implantable devices
US6862465B2 (en) 1997-03-04 2005-03-01 Dexcom, Inc. Device and method for determining analyte levels
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US8527026B2 (en) 1997-03-04 2013-09-03 Dexcom, Inc. Device and method for determining analyte levels
US6613583B1 (en) 1997-06-27 2003-09-02 Igen International, Inc. Electrochemiluminescent label based on multimetallic assemblies
DE19803528A1 (de) * 1998-01-30 1999-08-05 Roche Diagnostics Gmbh Verfahren zur Analyse einer Probe mittels eines Elektrochemolumineszenz-Bindungsreaktion-Tests
DE19811582A1 (de) * 1998-03-17 1999-09-23 Roche Diagnostics Gmbh Stabilisierung und Verstärkung von Elektrochemilumineszenz-Signalen
DE19828441A1 (de) * 1998-06-25 1999-12-30 Roche Diagnostics Gmbh Verwendung derivatisierter Reagenzien in Chemilumineszenz- und Elektrochemilumineszenz-Nachweisverfahren
US6214552B1 (en) 1998-09-17 2001-04-10 Igen International, Inc. Assays for measuring nucleic acid damaging activities
US6312896B1 (en) 1998-09-17 2001-11-06 Igen Inaternational, Inc. Assays for measuring nucleic acid binding proteins and enzyme activities
US7041807B1 (en) 1999-06-23 2006-05-09 Caprion Pharmaceuticals, Inc. Antibodies to a YYX epitope of a mammalian prion protein
JP2004534226A (ja) 2001-06-29 2004-11-11 メソ スケイル テクノロジーズ，エルエルシー 発光試験測定用のアッセイプレート、リーダシステム及び方法
US20030032874A1 (en) 2001-07-27 2003-02-13 Dexcom, Inc. Sensor head for use with implantable devices
US8815577B2 (en) 2001-07-30 2014-08-26 Meso Scale Technologies, Llc Assay electrode having immobilized lipid/protein layers, methods of making the same and methods of using the same for luminescence test measurements
CA2460114C (en) 2001-09-10 2012-11-06 Meso Scale Technologies, Llc Assay buffer, compositions containing the same, and methods of using the same
US9282925B2 (en) 2002-02-12 2016-03-15 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US10022078B2 (en) 2004-07-13 2018-07-17 Dexcom, Inc. Analyte sensor
US8260393B2 (en) 2003-07-25 2012-09-04 Dexcom, Inc. Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
US20040072236A1 (en) 2002-09-27 2004-04-15 Neil Cashman PrPSc -interacting molecules and uses thereof
US8423113B2 (en) 2003-07-25 2013-04-16 Dexcom, Inc. Systems and methods for processing sensor data
US8369919B2 (en) 2003-08-01 2013-02-05 Dexcom, Inc. Systems and methods for processing sensor data
US6931327B2 (en) 2003-08-01 2005-08-16 Dexcom, Inc. System and methods for processing analyte sensor data
US8160669B2 (en) 2003-08-01 2012-04-17 Dexcom, Inc. Transcutaneous analyte sensor
US8275437B2 (en) 2003-08-01 2012-09-25 Dexcom, Inc. Transcutaneous analyte sensor
US20080119703A1 (en) 2006-10-04 2008-05-22 Mark Brister Analyte sensor
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US20190357827A1 (en) 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
US7933639B2 (en) 2003-08-01 2011-04-26 Dexcom, Inc. System and methods for processing analyte sensor data
US20100168543A1 (en) 2003-08-01 2010-07-01 Dexcom, Inc. System and methods for processing analyte sensor data
US7774145B2 (en) 2003-08-01 2010-08-10 Dexcom, Inc. Transcutaneous analyte sensor
US8761856B2 (en) 2003-08-01 2014-06-24 Dexcom, Inc. System and methods for processing analyte sensor data
US8233959B2 (en) 2003-08-22 2012-07-31 Dexcom, Inc. Systems and methods for processing analyte sensor data
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US20140121989A1 (en) 2003-08-22 2014-05-01 Dexcom, Inc. Systems and methods for processing analyte sensor data
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US8615282B2 (en) 2004-07-13 2013-12-24 Dexcom, Inc. Analyte sensor
WO2005051170A2 (en) 2003-11-19 2005-06-09 Dexcom, Inc. Integrated receiver for continuous analyte sensor
US8364231B2 (en) 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
DE602004029092D1 (de) 2003-12-05 2010-10-21 Dexcom Inc Kalibrationsmethoden für einen kontinuierlich arbeitenden analytsensor
US11633133B2 (en) 2003-12-05 2023-04-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
EP2316331B1 (en) 2003-12-09 2016-06-29 Dexcom, Inc. Signal processing for continuous analyte sensor
US8808228B2 (en) 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
ITTO20040372A1 (it) 2004-06-01 2004-09-01 Giuseppe Caputo Composti luminescenti aventi un braccio di legame funzionalizzato.
EP1787124A2 (en) 2004-06-23 2007-05-23 The University Of Texas System Methods and compositions for the detection of biological molecules using a two particle complex
US7946984B2 (en) 2004-07-13 2011-05-24 Dexcom, Inc. Transcutaneous analyte sensor
US8452368B2 (en) 2004-07-13 2013-05-28 Dexcom, Inc. Transcutaneous analyte sensor
WO2006038686A1 (ja) * 2004-10-07 2006-04-13 Matsushita Electric Industrial Co., Ltd. 遺伝子検出方法、及び遺伝子検出装置
KR101311815B1 (ko) 2005-06-03 2013-10-22 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 단일 패러데이 전극에서의 전기발생 화학발광 및 전기화학
EP1950566A4 (en) * 2005-11-10 2008-11-26 Univ Toyama Nat Univ Corp METHOD FOR EVALUATING BINDING CHARACTERISTICS OF BIOSUBSTANCES AND BIOSUBSTANCE-BINDING SUBSTANCES
US8562558B2 (en) 2007-06-08 2013-10-22 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
EP4159114B1 (en) 2007-10-09 2024-04-10 DexCom, Inc. Integrated insulin delivery system with continuous glucose sensor
JP5576288B2 (ja) * 2007-11-21 2014-08-20 バイオ−ラッド ラボラトリーズ，インコーポレイティド タンパク質染色のための光ルミネセンス性金属複合体
EP2252196A4 (en) 2008-02-21 2013-05-15 Dexcom Inc SYSTEMS AND METHOD FOR PROCESSING, TRANSMITTING AND DISPLAYING SENSOR DATA
PL2271938T3 (pl) 2008-04-11 2014-07-31 Univ Texas Sposób i urządzenie do wzmacniania elektrogenerowanej chemiluminescencji nanocząsteczek
AU2009244904B2 (en) * 2008-05-08 2014-04-17 Board Of Regents Of The University Of Texas System Luminescent nanostructured materials for use in electrogenerated chemiluminescence
AU2014203680B2 (en) * 2008-05-08 2015-03-05 Board Of Regents Of The University Of Texas System Luminescent nanostructured materials for use in electrogenerated chemiluminescence
US8264347B2 (en) 2008-06-24 2012-09-11 Trelleborg Sealing Solutions Us, Inc. Seal system in situ lifetime measurement
FR2939895B1 (fr) * 2008-12-15 2011-01-14 Commissariat Energie Atomique Procede de detection non intrusive d'element chimique
EP4374790A3 (en) 2009-04-30 2024-07-31 DexCom, Inc. Performance reports associated with continuous sensor data from multiple analysis time periods
US20140038834A1 (en) 2010-07-07 2014-02-06 Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patiëntenzorg Novel biomarkers for detecting neuronal loss
ES2644816T3 (es) * 2011-02-09 2017-11-30 Hoffmann-La Roche Ag Nuevos complejos basados en iridio para ECL
US20120265036A1 (en) 2011-04-15 2012-10-18 Dexcom, Inc. Advanced analyte sensor calibration and error detection
US9442046B2 (en) 2011-06-19 2016-09-13 Abogen, Inc. Device for sample collection
EP2729809B1 (en) * 2011-07-07 2018-10-17 DuPont Nutrition Biosciences ApS Assay
US9081001B2 (en) 2012-05-15 2015-07-14 Wellstat Diagnostics, Llc Diagnostic systems and instruments
US9213043B2 (en) 2012-05-15 2015-12-15 Wellstat Diagnostics, Llc Clinical diagnostic system including instrument and cartridge
US9625465B2 (en) 2012-05-15 2017-04-18 Defined Diagnostics, Llc Clinical diagnostic systems
CA2879093C (en) 2012-08-02 2020-10-20 F. Hoffmann-La Roche Ag Bis-iridium-complexes for manufacturing of ecl-labels
BR112015023108A8 (pt) 2013-03-13 2018-01-23 Geneweave Biosciences Inc sistema de acondicionamento de célula bacteriana, método para acondicionamento de uma molécula de ácido nucléico repórter, composição, método para detectar uma presença ou uma ausência de uma célula bacteriana em uma amostra, vetor, método para detectar um transcrito alvo em uma célula, método para detectar a presença de uma célula bacteriana em uma amostra e kit.
US9481903B2 (en) 2013-03-13 2016-11-01 Roche Molecular Systems, Inc. Systems and methods for detection of cells using engineered transduction particles
US9540675B2 (en) 2013-10-29 2017-01-10 GeneWeave Biosciences, Inc. Reagent cartridge and methods for detection of cells
WO2015154189A1 (en) 2014-04-10 2015-10-15 Dna Genotek Inc. Method and system for microbial lysis using periodates
WO2016091755A1 (en) 2014-12-08 2016-06-16 F. Hoffmann-La Roche Ag Method for measurement of vitamin d
KR102601323B1 (ko) 2015-08-20 2023-11-10 에프. 호프만-라 로슈 아게 페길화 분석물-특이적 결합제를 사용하는 입자-기반 면역어세이
US10351893B2 (en) 2015-10-05 2019-07-16 GeneWeave Biosciences, Inc. Reagent cartridge for detection of cells
BR112018017336A2 (pt) 2016-03-07 2018-12-26 Hoffmann La Roche método in vitro para detectar um anticorpo para p53 (anticorpo anti-p53) em uma amostra e polipeptídeo de fusão
ES2974284T3 (es) 2016-03-11 2024-06-26 Roche Diagnostics Gmbh Aminas de cadena ramificada en la detección de electroquimioluminiscencia
JP7068323B2 (ja) 2017-02-02 2022-05-16 エフ．ホフマン－ラ ロシュ アーゲー 少なくとも２種のペグ化された分析物特異的結合剤を使用する免疫アッセイ
US11077444B2 (en) 2017-05-23 2021-08-03 Roche Molecular Systems, Inc. Packaging for a molecular diagnostic cartridge
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
CN111246797B (zh) 2017-10-24 2025-09-09 德克斯康公司 预连接分析物传感器
EP3781600A1 (en) 2018-04-18 2021-02-24 F. Hoffmann-La Roche AG Novel anti-thymidine kinase antibodies
WO2019215273A1 (en) 2018-05-09 2019-11-14 F. Hoffmann-La Roche Ag Devices and methods for determining particle concentration in a sample
WO2019223691A1 (zh) * 2018-05-21 2019-11-28 博阳生物科技（上海）有限公司 一种化学发光分析测定方法及使用该方法的系统、试剂盒
ES2983797T3 (es) 2018-08-31 2024-10-24 Hoffmann La Roche Timidina cinasa (TK-1) en índices pronóstico para LDLBG
EP4004551A1 (en) 2019-07-22 2022-06-01 F. Hoffmann-La Roche AG Substance p as blood biomarker for the non-invasive diagnosis of endometriosis
JP2022542056A (ja) 2019-07-22 2022-09-29 エフ．ホフマン－ラ ロシュ アーゲー 子宮内膜症の非侵襲的診断のための血液バイオマーカーとしてのｓ１００ａ６
JP7315781B2 (ja) 2019-07-22 2023-07-26 エフ． ホフマン－ラ ロシュ アーゲー 子宮内膜症の非侵襲的診断のための血液バイオマーカーとしてのｓ１００ａ１２
JP7421631B2 (ja) 2019-07-22 2024-01-24 エフ． ホフマン－ラ ロシュ アーゲー 子宮内膜症の非侵襲的診断のための血液バイオマーカーとしてのｓ１００ａ８
KR20220016210A (ko) 2019-07-22 2022-02-08 에프. 호프만-라 로슈 아게 자궁내막증의 비-침습적 진단용 혈액 생물표지자로써 s100a9
BR112022009371A2 (pt) 2019-11-15 2022-08-09 Hoffmann La Roche Métodos para determinar a quantidade ou concentração de um ou mais analitos antibióticos, tubos de amostragem, usos de um reagente de derivatização nucleofílica e analito antibiótico
KR20230065272A (ko) 2020-08-21 2023-05-11 메소 스케일 테크놀러지즈, 엘엘시 정의된 계면 전위를 갖는 보조 전극을 구비한 전기화학 셀 및 이를 사용하는 방법
WO2022090455A1 (en) 2020-11-02 2022-05-05 F. Hoffmann-La Roche Ag Sars-cov-2 nucleocapsid antibodies
WO2022207628A1 (en) 2021-03-30 2022-10-06 F. Hoffmann-La Roche Ag Scf as blood biomarker for the non-invasive diagnosis of endometriosis
CN117099001A (zh) 2021-04-01 2023-11-21 豪夫迈·罗氏有限公司 Psp94作为血液生物标志物用于子宫内膜异位症的非侵入性诊断
EP4341700A1 (en) 2021-05-17 2024-03-27 F. Hoffmann-La Roche AG Sfrp4 as blood biomarker for the non-invasive diagnosis of adenomyosis
AU2022325891B2 (en) 2021-08-13 2026-03-26 Meso Scale Technologies, Llc. Electrochemical cell devices and methods of manufacturing
US20250042976A1 (en) 2021-10-26 2025-02-06 Roche Diagnostics Operations, Inc. Monoclonal antibodies specific for sars-cov-2 rbd
JP2025501000A (ja) 2022-01-04 2025-01-15 メソ スケール テクノロジーズ エルエルシー 電気化学セルデバイスおよびその製造方法
WO2023131594A1 (en) 2022-01-05 2023-07-13 F. Hoffmann-La Roche Ag Derivatization of compounds in patient samples for therapeutic drug monitoring (tdm)
WO2023247752A1 (en) 2022-06-23 2023-12-28 F. Hoffmann-La Roche Ag Method for diagnosing endometriosis and for classifying the stage of endometriosis
JP2025524025A (ja) 2022-07-22 2025-07-25 エフ． ホフマン－ラ ロシュ アーゲー 多嚢胞性卵巣症候群の診断のための（血液）バイオマーカーとしてのロイコトリエンａ４ヒドロラーゼ（ｌｔａ４ｈ）
EP4558826A1 (en) 2022-07-22 2025-05-28 F. Hoffmann-La Roche AG Fibroblast growth factor binding protein 1 (fgfbp1) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome
EP4558825A1 (en) 2022-07-22 2025-05-28 F. Hoffmann-La Roche AG Meteorin-like protein (metrnl) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome
IL322791A (en) 2023-02-15 2025-10-01 Meso Scale Technologies Llc Electrochemical cell devices and methods for their manufacture
CN116832862B (zh) * 2023-05-23 2024-06-25 杭州师范大学 一种超薄金-锰纳米复合材料、制备方法及其在检测领域中的应用
EP4747637A1 (en) 2023-07-20 2026-05-27 F. Hoffmann-La Roche AG Screening methods for antibody compositions
JP2026526931A (ja) 2023-07-28 2026-08-10 エフ ホフマン－ラ ロッシュ アクチェン ゲゼルシャフト 子宮内膜症のバイオマーカーとしての血清ＥｐｈＡ１
WO2026120128A1 (en) 2024-12-05 2026-06-11 Roche Diagnostics Gmbh Serum transcriptional regulator erg as biomarker for endometriosis

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL49685A (en) * 1976-05-31 1978-10-31 Technion Res & Dev Foundation Specific binding assay method for determining the concentration of materials and reagent means therefor
US4233144A (en) * 1979-04-16 1980-11-11 Technicon Instruments Corporation Electrode for voltammetric immunoassay
US4280815A (en) * 1979-06-18 1981-07-28 Technicon Instruments Corporation Electrochemiluminescent immunoassay and apparatus therefor
WO1981001883A1 (en) * 1979-12-19 1981-07-09 Electro Nucleonics Chemical luminescence amplification substrate system for immunochemistry
US4293310A (en) * 1980-03-14 1981-10-06 University Of Pittsburgh Photoelectrochemical immunoassay
EP0063810B1 (en) * 1981-04-29 1986-03-05 Ciba-Geigy Ag New devices and kits for immunological analysis
US4514508A (en) * 1982-07-06 1985-04-30 Biond Inc. Assaying for a multiplicity of antigens or antibodies with a detection compound
GB2135773B (en) * 1983-01-31 1985-12-04 Boots Celltech Diagnostics Enzyme inhibitor labelled immunoassay
EP0139373A1 (en) * 1983-08-26 1985-05-02 The Regents Of The University Of California Multiple immunoassay system
IL75464A (en) * 1984-06-12 1990-08-31 Orgenics Ltd Method and apparatus for multi-analyte assay
CA1340372C (en) * 1984-07-09 1999-02-02 John D. Clements Production of e. coli lt-b enterotoxin subunit
DK365785A (da) * 1984-09-17 1986-03-18 Hoffmann La Roche Metalcomplexer
US4617265A (en) * 1984-09-19 1986-10-14 Board Of Regents, University Of Texas System Colony blot assay for enterotoxigenic bacteria
US5238808A (en) * 1984-10-31 1993-08-24 Igen, Inc. Luminescent metal chelate labels and means for detection
US5120662A (en) * 1989-05-09 1992-06-09 Abbott Laboratories Multilayer solid phase immunoassay support and method of use
EP0533753A1 (en) 1990-06-14 1993-03-31 Washington University Rna hydrolysis/cleavage

Also Published As

Publication number Publication date
JPH07309836A (ja) 1995-11-28
JPH07267972A (ja) 1995-10-17
FI102017B (fi) 1998-09-30
JP3509812B2 (ja) 2004-03-22
JP3349279B2 (ja) 2002-11-20
AU605158B2 (en) 1991-01-10
DE3752345T2 (de) 2002-08-22
JPH0737464B2 (ja) 1995-04-26
KR880701379A (ko) 1988-07-26
EP0658564A1 (en) 1995-06-21
HK1007442A1 (en) 1999-04-09
NO875476D0 (no) 1987-12-29
JPH01500146A (ja) 1989-01-19
HK1013653A1 (en) 1999-09-03
CA1339465C (en) 1997-09-16
EP0647849A2 (en) 1995-04-12
AU7433891A (en) 1991-08-08
JP2648474B2 (ja) 1997-08-27
WO1987006706A1 (en) 1987-11-05
JP2003128689A (ja) 2003-05-08
DE3751516T2 (de) 1996-02-15
ATE212030T1 (de) 2002-02-15
AU685071B2 (en) 1998-01-15
IL82411A0 (en) 1987-11-30
EP0265519A4 (en) 1990-05-14
JPH09118688A (ja) 1997-05-06
EP0265519A1 (en) 1988-05-04
EP0265519B1 (en) 1995-09-13
JP3476679B2 (ja) 2003-12-10
DK16293D0 (da) 1993-02-12
DE3751516D1 (de) 1995-10-19
AU7581687A (en) 1987-11-24
FI875732A7 (fi) 1987-12-28
FI102017B1 (fi) 1998-09-30
FI875732A0 (fi) 1987-12-28
NO875476L (no) 1988-02-23
DK173025B1 (da) 1999-11-15
DE3752345D1 (de) 2002-02-21
AU5754094A (en) 1994-05-12
JPH11101800A (ja) 1999-04-13
EP0658564B1 (en) 2002-01-16
NO176071B (no) 1994-10-17
EP0647849A3 (en) 1996-05-15
AU644150B2 (en) 1993-12-02
JP2674957B2 (ja) 1997-11-12
KR960016340B1 (ko) 1996-12-09
NO176071C (no) 1995-01-25
ATE127923T1 (de) 1995-09-15

Similar Documents

Publication Publication Date Title
DK16293D0 (da) Ruthenium og osmium-komplekser til brug ved kvalitativ og kvantitativ elektrokemiluminiscerende analysering af multikomponentvaesker samt biologiske forbindelser indeholdende disse komplekser
FI895505A0 (fi) Menetelmä ja reagenssipakkaus endotoksiinin tai endotoksiinin kaltaisen aineen määrittämiseksi näytteestä sekä menetelmässä käytettäväksi tarkoitetut monoklonaaliset vasta-aineet
DE3580640D1 (de) Testverfahren.
ATE329054T1 (de) Sätze von hiv sonden für solution sandwich hybridationsverfahren
EP0417305A4 (en) Analyzer of liquid sample and analyzing method of liquid sample using said analyzer
DE69231693D1 (de) Hbv amplifizierungssonden zur verwendung in hybridisierungssandwichassay in der lösungsphase
ATE142622T1 (de) Elektrochemilumineszente rhenium-fraktionen und verfahren
ATE162891T1 (de) Verfahren und zusammensetzungen für enzymkomplimentationassays unter verwendung der omega-region der beta-galactosidase
ATE85363T1 (de) Verfahren und reagenz zur bestimmung von alphaamylase.
NO943759D0 (no) Fremgangsmåte for bestemmelse av mengden av en ligand i et biologisk fluid, samt et analysesett for utförelse av en slik fremgangsmåte
EP0724619A4 (en) CLEANING SOLUTION FOR ANALYZER
JPS5714748A (en) Kit for quantitative determination of valproic acid and its method for quantitative determination
ATE145480T1 (de) Verfahren zur bestimmung eines analyten
SE8604010D0 (sv) Simulatenous extraction of a ligand from a sample and capture by anti-ligands therefor in ligand/anti-ligand assays
KR940000870A (ko) β-N- 아세틸글루코사미니다제의 샌드위치 면역 측정법 및 그 측정법에 사용된 모노클론 항체
DK480189D0 (da) Fremgangsmaade til bestemmelse af cerealiekvalitet
DE69032444D1 (de) Verfahren zum testen von öl
AU3106589A (en) Agent, for immunochemical assays, containing amine oxides
DE59310190D1 (de) Immunchemisches Verfahren zum Nachweis eines Analyten

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired