HK1004218A1 - Process for the preparation of n-methyl-3-(1-methyl-4-piperidinyl)-14-indole-5-ethanesulphonamide - Google Patents

Process for the preparation of n-methyl-3-(1-methyl-4-piperidinyl)-14-indole-5-ethanesulphonamide

Info

Publication number
HK1004218A1
HK1004218A1 HK98103467A HK98103467A HK1004218A1 HK 1004218 A1 HK1004218 A1 HK 1004218A1 HK 98103467 A HK98103467 A HK 98103467A HK 98103467 A HK98103467 A HK 98103467A HK 1004218 A1 HK1004218 A1 HK 1004218A1
Authority
HK
Hong Kong
Prior art keywords
methyl
ethanesulphonamide
piperidinyl
indole
preparation
Prior art date
Application number
HK98103467A
Other languages
English (en)
Inventor
Philip Blatcher
Malcolm Carter
Roy Hornby
Martin Richard Owen
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of HK1004218A1 publication Critical patent/HK1004218A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK98103467A 1993-09-29 1998-04-24 Process for the preparation of n-methyl-3-(1-methyl-4-piperidinyl)-14-indole-5-ethanesulphonamide HK1004218A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939320115A GB9320115D0 (en) 1993-09-29 1993-09-29 Process
PCT/EP1994/003216 WO1995009166A1 (en) 1993-09-29 1994-09-27 Process for the preparation of n-methyl-3-(1-methyl-4-piperidinyl)-14-indole-5-ethanesulphonamide

Publications (1)

Publication Number Publication Date
HK1004218A1 true HK1004218A1 (en) 1998-11-20

Family

ID=10742727

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98103467A HK1004218A1 (en) 1993-09-29 1998-04-24 Process for the preparation of n-methyl-3-(1-methyl-4-piperidinyl)-14-indole-5-ethanesulphonamide

Country Status (32)

Country Link
US (2) US5659040A (fi)
EP (1) EP0721453B1 (fi)
JP (1) JP3411284B2 (fi)
CN (2) CN1132509A (fi)
AP (1) AP529A (fi)
AT (1) ATE228124T1 (fi)
AU (1) AU682219B2 (fi)
CA (1) CA2170645C (fi)
CO (1) CO4290351A1 (fi)
CZ (1) CZ287581B6 (fi)
DE (1) DE69431759T2 (fi)
DK (1) DK0721453T3 (fi)
ES (1) ES2187534T3 (fi)
FI (1) FI111162B (fi)
GB (1) GB9320115D0 (fi)
HK (1) HK1004218A1 (fi)
HR (1) HRP940613B1 (fi)
HU (1) HU226828B1 (fi)
IL (1) IL111071A (fi)
IS (1) IS1877B (fi)
MY (1) MY117934A (fi)
NO (1) NO309324B1 (fi)
NZ (1) NZ274159A (fi)
PE (1) PE18195A1 (fi)
PL (1) PL178456B1 (fi)
PT (1) PT721453E (fi)
RU (1) RU2143428C1 (fi)
SG (1) SG49322A1 (fi)
SI (1) SI0721453T1 (fi)
SK (1) SK282234B6 (fi)
WO (1) WO1995009166A1 (fi)
ZA (1) ZA947516B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6673827B1 (en) 1999-06-29 2004-01-06 The Uab Research Foundation Methods of treating fungal infections with inhibitors of NAD synthetase enzyme
US6861448B2 (en) * 1998-01-14 2005-03-01 Virtual Drug Development, Inc. NAD synthetase inhibitors and uses thereof
CA2317439A1 (en) 1998-01-14 1999-07-22 Wayne J. Brouillette Methods of synthesizing and screening inhibitors of bacterial nad synthetase enzyme, compounds thereof, and methods of treating bacterial and microbial infections with inhibitors of bacterial nad synthetase enzyme
WO2006010079A2 (en) * 2004-07-08 2006-01-26 Dr. Reddy's Laboratories Ltd. Process for preparing naratriptan hydrochloride
WO2006010078A2 (en) * 2004-07-08 2006-01-26 Dr. Reddy's Laboratories Ltd. Polymorphic form of naratriptan hydrochloride
CN1315821C (zh) * 2004-12-16 2007-05-16 上海美通生物科技有限公司 制备n-甲基-3-(1-甲基-4-哌啶基)-1,4-吲哚-5-乙硫胺的改进法
AU2006306497A1 (en) * 2005-10-24 2007-05-03 Janssen Pharmaceutica, N.V. 3-piperidin-4-yl-indole ORL-1 receptor modulators
WO2009118753A2 (en) * 2008-03-07 2009-10-01 Usv Limited Process for preparation of naratriptan hydrochloride
CN101676283A (zh) * 2008-09-17 2010-03-24 北京德众万全药物技术开发有限公司 一种那拉曲坦的制备方法
KR20120084286A (ko) 2009-08-20 2012-07-27 시플라 리미티드 나라트립탄의 합성방법
CN101792411B (zh) * 2010-03-26 2012-05-30 常州晟永光电材料有限公司 一种合成乙磺酰胺的方法
CN103073484B (zh) * 2013-01-28 2014-10-22 山东诚创医药技术开发有限公司 一种甲哌卡因及其光学对映体的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4997841A (en) * 1987-08-13 1991-03-05 Glaxo Group Limited Indole derivatives
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
GB8903036D0 (en) * 1989-02-10 1989-03-30 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
FI961378A0 (fi) 1996-03-26
HRP940613B1 (en) 2003-10-31
AU682219B2 (en) 1997-09-25
CZ287581B6 (en) 2000-12-13
CN1132509A (zh) 1996-10-02
GB9320115D0 (en) 1993-11-17
IS4212A (is) 1995-03-30
FI961378A (fi) 1996-03-26
FI111162B (fi) 2003-06-13
US5659040A (en) 1997-08-19
EP0721453B1 (en) 2002-11-20
HU9600814D0 (en) 1996-05-28
IL111071A0 (en) 1994-11-28
WO1995009166A1 (en) 1995-04-06
CN1332166A (zh) 2002-01-23
CO4290351A1 (es) 1996-04-17
NO961252D0 (no) 1996-03-28
SG49322A1 (en) 1998-05-18
DK0721453T3 (da) 2003-03-17
MY117934A (en) 2004-08-30
CA2170645A1 (en) 1995-04-06
ATE228124T1 (de) 2002-12-15
NO961252L (no) 1996-03-28
NO309324B1 (no) 2001-01-15
AP9400676A0 (en) 1994-10-31
PT721453E (pt) 2003-03-31
AP529A (en) 1996-09-09
CA2170645C (en) 2005-11-15
ZA947516B (en) 1995-06-12
DE69431759T2 (de) 2003-07-03
RU2143428C1 (ru) 1999-12-27
HUT75642A (en) 1997-05-28
EP0721453A1 (en) 1996-07-17
PL178456B1 (pl) 2000-05-31
JP3411284B2 (ja) 2003-05-26
SK40696A3 (en) 1996-10-02
SI0721453T1 (en) 2003-04-30
IL111071A (en) 1998-10-30
JPH09502991A (ja) 1997-03-25
IS1877B (is) 2003-06-20
PL313740A1 (en) 1996-07-22
SK282234B6 (sk) 2001-12-03
US5786473A (en) 1998-07-28
HU226828B1 (en) 2009-11-30
DE69431759D1 (de) 2003-01-02
ES2187534T3 (es) 2003-06-16
HRP940613A2 (en) 1997-06-30
PE18195A1 (es) 1995-07-27
AU7810194A (en) 1995-04-18
CZ76896A3 (en) 1996-06-12
NZ274159A (en) 1997-09-22

Similar Documents

Publication Publication Date Title
IL117188A0 (en) Process for the preparation of thietanones
SG55239A1 (en) Process for the preparation of dihaloazpyrimidines
HUP9603081A3 (en) Process for the preparation of bis(silyl-alkyl)-disulfides
EP0699695A3 (de) Verfahren zur Herstellung von Polyacetalcopolymeren
ZA954324B (en) Process for the preparation of 3-aryluracils
GB9311509D0 (en) Process for the preparation of organopolysiloxanes
HK1004218A1 (en) Process for the preparation of n-methyl-3-(1-methyl-4-piperidinyl)-14-indole-5-ethanesulphonamide
SG46689A1 (en) Process for the preparation of 2-h-heptafluoropropane
GB9509826D0 (en) Process for the preparation of imidazolutidine
HUT67641A (en) Process for preparation of difluoromethoxy- and difluoromethylthioarenes
IL118200A0 (en) Process for the preparation of substituted 2-fluoro-pyrimidines
GB9317342D0 (en) Process for the preparation of fullerenes
HUT65321A (en) Process for preparation of-n-acylated-p-phends
GB9416728D0 (en) Process for the preparation of 4-chloro-2-cyclopropylcarhbonylaniline
IL115090A0 (en) Process for the preparation of p-bromofluorobenzene
IL118973A0 (en) Process for the preparation of substituted aminocarbonyltriazolinones
HU9303010D0 (en) Process for preparation of 2-methyl-thiazole-5-carboxylates
IL116493A0 (en) Process for the preparation of sameridine
ZA9510894B (en) Process for the preparation of chloromethylpyridines
HUT67910A (en) Process for preparation of 4-alkane-aryl-benzylethers
IL118732A (en) Process for the preparation of arylidene-substituted alkylcycloalkanones
IL118747A (en) Process for the preparation of 3-hydroxyoxetanes
EP0690056A3 (de) Verfahren zur Herstellung von Purinen
ZA945561B (en) Process for the preparation of difluorobetenylmercaptoheterocyclics
EP0550871A3 (en) Process for the preparation of cycloalcanols

Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090927