HK1001729A1 - Spicamycin derivatives and the use thereof - Google Patents

Spicamycin derivatives and the use thereof

Info

Publication number
HK1001729A1
HK1001729A1 HK98100557A HK98100557A HK1001729A1 HK 1001729 A1 HK1001729 A1 HK 1001729A1 HK 98100557 A HK98100557 A HK 98100557A HK 98100557 A HK98100557 A HK 98100557A HK 1001729 A1 HK1001729 A1 HK 1001729A1
Authority
HK
Hong Kong
Prior art keywords
chem
denotes
integer
carbon atoms
given number
Prior art date
Application number
HK98100557A
Other languages
English (en)
Inventor
Noboru Otake
Hiroyuki Kawai
Tomiko Kawasaki
Atsuo Odagawa
Masaru Kamishohara
Teruyuki Sakai
Original Assignee
Kirin Brewery
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kirin Brewery filed Critical Kirin Brewery
Publication of HK1001729A1 publication Critical patent/HK1001729A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HK98100557A 1991-07-12 1998-01-21 Spicamycin derivatives and the use thereof HK1001729A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP19890391 1991-07-12
JP32684591 1991-11-15
JP4110665A JP2783722B2 (ja) 1991-07-12 1992-04-03 スピカマイシン誘導体およびそれを含む抗腫瘍剤

Publications (1)

Publication Number Publication Date
HK1001729A1 true HK1001729A1 (en) 1998-07-03

Family

ID=27311786

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98100557A HK1001729A1 (en) 1991-07-12 1998-01-21 Spicamycin derivatives and the use thereof

Country Status (16)

Country Link
US (2) US5461036A (xx)
EP (1) EP0525479B1 (xx)
JP (1) JP2783722B2 (xx)
KR (1) KR100253050B1 (xx)
AT (1) ATE159948T1 (xx)
AU (1) AU657551B2 (xx)
CA (1) CA2073567C (xx)
DE (1) DE69222992T2 (xx)
DK (1) DK0525479T3 (xx)
ES (1) ES2111019T3 (xx)
FI (1) FI105815B (xx)
GR (1) GR3025293T3 (xx)
HK (1) HK1001729A1 (xx)
HU (1) HU221808B1 (xx)
NO (1) NO178500C (xx)
SG (1) SG52704A1 (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7017208B2 (en) * 1995-08-04 2006-03-28 Hill-Rom Services, Inc. Hospital bed
US5905069A (en) * 1998-01-26 1999-05-18 The General Hospital Corporation Methods of decreasing or preventing pain using spicamycin or derivatives thereof
EP1384712B1 (en) * 1999-01-22 2007-03-07 Kirin Beer Kabushiki Kaisha Derivatives of N-((quinolinyl)oxy)-phenyl)-urea and N-((quinazolinyl)oxy)-phenyl)-urea with antitumor activity
EP2305264A1 (en) 2000-09-20 2011-04-06 The General Hospital Corporation Spicamycin derivatives for use in decreasing or preventing pain
CA2506236C (en) * 2002-11-18 2018-07-17 Vicuron Pharmaceuticals Inc. Compositions and uses of dalbavancin for treatment of bacterial infections
US20060074014A1 (en) * 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
EP1663957B1 (en) * 2003-09-11 2009-08-05 INVISTA Technologies S.à.r.l. Process of hydrocyanation of unsaturated carboxylic acid derivatives
JP4608651B2 (ja) * 2004-06-24 2011-01-12 財団法人ヒューマンサイエンス振興財団 抗ガン作用を有する化合物、その製造方法及び抗ガン剤
US8119829B2 (en) * 2004-09-08 2012-02-21 Invista North America S.A.R.L. Process of hydrocyanation of unsaturated carboxylic acid derivatives
JP5753784B2 (ja) * 2008-10-10 2015-07-22 ダラ・バイオサイエンシズ,インコーポレイテッド スピカマイシン誘導体を用いて疼痛を治療又は予防する方法
EP2597082A1 (de) 2011-11-24 2013-05-29 Symrise AG Verbindungen zur Maskierung eines unangenehmen Geschmacks
WO2014025979A1 (en) 2012-08-09 2014-02-13 Dara Biosciences, Inc. Compositions comprising spicamycin derivatives and methods of use thereof
WO2015061481A1 (en) 2013-10-23 2015-04-30 Dara Biosciences, Inc. Methods of treating liquid tumors using compositions comprising spicamycin derivatives
CN110386874B (zh) * 2018-04-16 2022-10-04 湖北金鹤化工有限公司 一种12-酮基硬脂酸酯及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155647A (en) 1963-07-24 1964-11-03 Olin Mathieson Septaciding and derivatives thereof
US3264195A (en) * 1963-07-24 1966-08-02 Squibb & Sons Inc Process for the preparation of septacidin and derivatives
US4086416A (en) * 1977-05-17 1978-04-25 Stanford Research Institute Septacidin analogs
JPS59161389A (ja) * 1983-03-07 1984-09-12 Eisai Co Ltd 7−カルボキシメトキシフエニルアセトアミドセフエム誘導体,その製造法およびそれからなる抗菌剤
JPS59161396A (ja) * 1983-03-04 1984-09-12 Kirin Brewery Co Ltd 新規抗生物質スピカマイシン
US4975434A (en) * 1986-05-27 1990-12-04 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Antiviral and anticancer cyclopentenyl cytosine
WO1990015811A1 (en) 1989-06-16 1990-12-27 Kirin Beer Kabushiki Kaisha Spicamycin x and its use

Also Published As

Publication number Publication date
DE69222992D1 (de) 1997-12-11
FI923170A0 (fi) 1992-07-09
JP2783722B2 (ja) 1998-08-06
EP0525479A1 (en) 1993-02-03
NO922674D0 (no) 1992-07-08
HUT61773A (en) 1993-03-01
NO178500B (no) 1996-01-02
FI105815B (fi) 2000-10-13
HU9202285D0 (en) 1992-10-28
JPH05186494A (ja) 1993-07-27
DK0525479T3 (da) 1998-04-20
ATE159948T1 (de) 1997-11-15
ES2111019T3 (es) 1998-03-01
FI923170A (fi) 1993-01-13
NO178500C (no) 1996-04-10
CA2073567A1 (en) 1993-01-13
AU657551B2 (en) 1995-03-16
GR3025293T3 (en) 1998-02-27
HU221808B1 (hu) 2003-01-28
KR930002370A (ko) 1993-02-23
US5461036A (en) 1995-10-24
NO922674L (no) 1993-01-13
CA2073567C (en) 1998-05-05
US5631238A (en) 1997-05-20
KR100253050B1 (ko) 2000-04-15
DE69222992T2 (de) 1998-03-05
AU1960092A (en) 1993-01-14
SG52704A1 (en) 1998-09-28
EP0525479B1 (en) 1997-11-05

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20100710