DE69222992D1 - Spicamycinderivate und deren Verwendung - Google Patents

Spicamycinderivate und deren Verwendung

Info

Publication number
DE69222992D1
DE69222992D1 DE69222992T DE69222992T DE69222992D1 DE 69222992 D1 DE69222992 D1 DE 69222992D1 DE 69222992 T DE69222992 T DE 69222992T DE 69222992 T DE69222992 T DE 69222992T DE 69222992 D1 DE69222992 D1 DE 69222992D1
Authority
DE
Germany
Prior art keywords
chem
denotes
integer
carbon atoms
given number
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69222992T
Other languages
English (en)
Other versions
DE69222992T2 (de
Inventor
Noboru Otake
Hiroyuki Kawai
Tomiko Kawasaki
Atsuo Odagawa
Masaru Kamishohara
Teruyuki Sakai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyowa Kirin Co Ltd
Original Assignee
Kirin Brewery Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kirin Brewery Co Ltd filed Critical Kirin Brewery Co Ltd
Application granted granted Critical
Publication of DE69222992D1 publication Critical patent/DE69222992D1/de
Publication of DE69222992T2 publication Critical patent/DE69222992T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69222992T 1991-07-12 1992-07-10 Spicamycinderivate und deren Verwendung Expired - Lifetime DE69222992T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP19890391 1991-07-12
JP32684591 1991-11-15
JP4110665A JP2783722B2 (ja) 1991-07-12 1992-04-03 スピカマイシン誘導体およびそれを含む抗腫瘍剤

Publications (2)

Publication Number Publication Date
DE69222992D1 true DE69222992D1 (de) 1997-12-11
DE69222992T2 DE69222992T2 (de) 1998-03-05

Family

ID=27311786

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69222992T Expired - Lifetime DE69222992T2 (de) 1991-07-12 1992-07-10 Spicamycinderivate und deren Verwendung

Country Status (16)

Country Link
US (2) US5461036A (de)
EP (1) EP0525479B1 (de)
JP (1) JP2783722B2 (de)
KR (1) KR100253050B1 (de)
AT (1) ATE159948T1 (de)
AU (1) AU657551B2 (de)
CA (1) CA2073567C (de)
DE (1) DE69222992T2 (de)
DK (1) DK0525479T3 (de)
ES (1) ES2111019T3 (de)
FI (1) FI105815B (de)
GR (1) GR3025293T3 (de)
HK (1) HK1001729A1 (de)
HU (1) HU221808B1 (de)
NO (1) NO178500C (de)
SG (1) SG52704A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7017208B2 (en) * 1995-08-04 2006-03-28 Hill-Rom Services, Inc. Hospital bed
US5905069A (en) * 1998-01-26 1999-05-18 The General Hospital Corporation Methods of decreasing or preventing pain using spicamycin or derivatives thereof
US6797823B1 (en) * 1999-01-22 2004-09-28 Kirin Beer Kabushiki Kaisha Quinoline derivatives and quinazoline derivatives
EP1328236B1 (de) * 2000-09-20 2011-04-06 The General Hospital Corporation Methoden zur verminderung oder verhinderung von schmerzen mit spicamycin-derivaten
US20060074014A1 (en) * 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
WO2004045637A1 (en) * 2002-11-18 2004-06-03 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
JP2007505123A (ja) * 2003-09-11 2007-03-08 インヴィスタ テクノロジー エスアエルエル 不飽和カルボン酸誘導体のヒドロシアン化方法
JP4608651B2 (ja) * 2004-06-24 2011-01-12 財団法人ヒューマンサイエンス振興財団 抗ガン作用を有する化合物、その製造方法及び抗ガン剤
US8119829B2 (en) * 2004-09-08 2012-02-21 Invista North America S.A.R.L. Process of hydrocyanation of unsaturated carboxylic acid derivatives
EP2349285B1 (de) * 2008-10-10 2016-03-23 Dara Biosciences, Inc. Spicamycin-Derivat Enthaltend Nanoemulsionen zur Verwendundung in der Behandlung von Schmerzen
EP2597082A1 (de) 2011-11-24 2013-05-29 Symrise AG Verbindungen zur Maskierung eines unangenehmen Geschmacks
KR20150038572A (ko) * 2012-08-09 2015-04-08 다라 바이오싸이언시즈, 아이엔씨. 스피카마이신 유도체를 포함하는 조성물 및 이의 사용 방법
WO2015061481A1 (en) 2013-10-23 2015-04-30 Dara Biosciences, Inc. Methods of treating liquid tumors using compositions comprising spicamycin derivatives
CN110386874B (zh) * 2018-04-16 2022-10-04 湖北金鹤化工有限公司 一种12-酮基硬脂酸酯及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3264195A (en) * 1963-07-24 1966-08-02 Squibb & Sons Inc Process for the preparation of septacidin and derivatives
US3155647A (en) 1963-07-24 1964-11-03 Olin Mathieson Septaciding and derivatives thereof
US4086416A (en) * 1977-05-17 1978-04-25 Stanford Research Institute Septacidin analogs
JPS59161389A (ja) * 1983-03-07 1984-09-12 Eisai Co Ltd ７−カルボキシメトキシフエニルアセトアミドセフエム誘導体，その製造法およびそれからなる抗菌剤
JPS59161396A (ja) * 1983-03-04 1984-09-12 Kirin Brewery Co Ltd 新規抗生物質スピカマイシン
US4975434A (en) * 1986-05-27 1990-12-04 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Antiviral and anticancer cyclopentenyl cytosine
WO1990015811A1 (en) 1989-06-16 1990-12-27 Kirin Beer Kabushiki Kaisha Spicamycin x and its use

Also Published As

Publication number Publication date
HU221808B1 (hu) 2003-01-28
EP0525479A1 (de) 1993-02-03
NO178500C (no) 1996-04-10
JP2783722B2 (ja) 1998-08-06
NO922674D0 (no) 1992-07-08
KR930002370A (ko) 1993-02-23
US5461036A (en) 1995-10-24
EP0525479B1 (de) 1997-11-05
FI923170A0 (fi) 1992-07-09
FI923170A (fi) 1993-01-13
US5631238A (en) 1997-05-20
ATE159948T1 (de) 1997-11-15
CA2073567C (en) 1998-05-05
KR100253050B1 (ko) 2000-04-15
DE69222992T2 (de) 1998-03-05
HUT61773A (en) 1993-03-01
AU657551B2 (en) 1995-03-16
FI105815B (fi) 2000-10-13
CA2073567A1 (en) 1993-01-13
JPH05186494A (ja) 1993-07-27
HK1001729A1 (en) 1998-07-03
ES2111019T3 (es) 1998-03-01
DK0525479T3 (da) 1998-04-20
AU1960092A (en) 1993-01-14
SG52704A1 (en) 1998-09-28
GR3025293T3 (en) 1998-02-27
HU9202285D0 (en) 1992-10-28
NO922674L (no) 1993-01-13
NO178500B (no) 1996-01-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: PATENTANWAELTE REICHEL UND REICHEL, 60322 FRANKFURT

8327 Change in the person/name/address of the patent owner

Owner name: KIRIN PHARMA KABUSHIKI KAISHA, SHIBUYA, TOKYO, JP

8328 Change in the person/name/address of the agent

Representative=s name: 2K PATENTANWAELTE BLASBERG KEWITZ & REICHEL, PARTN

8327 Change in the person/name/address of the patent owner

Owner name: KYOWA HAKKO KIRIN CO., LTD., TOKYO, JP

R071 Expiry of right

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