HK1000313A1 - Novel controlled release formulations of tetracycline compounds - Google Patents

Novel controlled release formulations of tetracycline compounds Download PDF

Info

Publication number
HK1000313A1
HK1000313A1 HK97101882A HK97101882A HK1000313A1 HK 1000313 A1 HK1000313 A1 HK 1000313A1 HK 97101882 A HK97101882 A HK 97101882A HK 97101882 A HK97101882 A HK 97101882A HK 1000313 A1 HK1000313 A1 HK 1000313A1
Authority
HK
Hong Kong
Prior art keywords
deoxy
demethyltetracycline
tetracycline compound
microcrystalline cellulose
granules
Prior art date
Application number
HK97101882A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1000313B (en
Inventor
J. Valerose Joseph
J. Biehl Raymond
V. Sheth Nitin
A. Strathy Walter
Kay Doelling Michael
Original Assignee
Wyeth Holdings Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22303124&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1000313(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Holdings Corporation filed Critical Wyeth Holdings Corporation
Publication of HK1000313B publication Critical patent/HK1000313B/en
Publication of HK1000313A1 publication Critical patent/HK1000313A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
HK97101882A 1987-10-06 1997-10-04 Novel controlled release formulations of tetracycline compounds HK1000313A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US104917 1987-10-06
US07/104,917 US4837030A (en) 1987-10-06 1987-10-06 Novel controlled release formulations of tetracycline compounds

Publications (2)

Publication Number Publication Date
HK1000313B HK1000313B (en) 1998-02-27
HK1000313A1 true HK1000313A1 (en) 1998-02-27

Family

ID=22303124

Family Applications (1)

Application Number Title Priority Date Filing Date
HK97101882A HK1000313A1 (en) 1987-10-06 1997-10-04 Novel controlled release formulations of tetracycline compounds

Country Status (24)

Country Link
US (1) US4837030A (cs)
EP (1) EP0310814B1 (cs)
JP (1) JP2771189B2 (cs)
KR (1) KR970007902B1 (cs)
AR (1) AR243077A1 (cs)
AT (1) ATE120957T1 (cs)
AU (1) AU609525B2 (cs)
CA (1) CA1338439C (cs)
CZ (1) CZ279809B6 (cs)
DE (1) DE3853566T2 (cs)
DK (1) DK175578B1 (cs)
ES (1) ES2070837T3 (cs)
FI (1) FI97862C (cs)
GR (1) GR3015767T3 (cs)
HK (1) HK1000313A1 (cs)
HU (1) HU202110B (cs)
IL (1) IL87699A (cs)
NO (1) NO175619C (cs)
NZ (1) NZ226396A (cs)
PH (1) PH27236A (cs)
PL (1) PL275089A1 (cs)
PT (1) PT88664B (cs)
SK (1) SK656388A3 (cs)
ZA (1) ZA887478B (cs)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2061623T3 (es) * 1987-03-02 1994-12-16 Brocades Pharma Bv Procedimiento para la obtencion de una composicion farmaceutica y un granulado farmaceutico.
US5211958A (en) * 1987-11-30 1993-05-18 Gist-Brocades, N.V. Pharmaceutical composition and process for its preparation
US5277916A (en) * 1988-02-01 1994-01-11 F. H. Faulding & Co., Ltd. Tetracycline dosage form
DE68916983T2 (de) * 1988-02-25 1995-01-19 Yamanouchi Europ Bv Verfahren zur Herstellung eines pharmazeutischen Granulats.
EP0418596A3 (en) * 1989-09-21 1991-10-23 American Cyanamid Company Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form
ES2064564T3 (es) * 1989-09-21 1995-02-01 American Cyanamid Co Sistema de liberacion pulsatil de dosis unitaria diaria de minociclina.
EP0418597A3 (en) * 1989-09-21 1991-11-27 American Cyanamid Company Controlled release carbonic anhydrase inhibitor containing pharmaceutical compositions from spherical granules in capsule oral dosage unit form
US5460825A (en) * 1990-05-23 1995-10-24 Mcneil-Ppc, Inc. Taste mask coatings for preparing chewable pharmaceutical tablets
US5260072A (en) * 1990-08-30 1993-11-09 Mcneil-Ppc, Inc. Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
USRE40183E1 (en) 1991-10-04 2008-03-25 Wyeth Holdings Corporation 7-Substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
US5494903A (en) 1991-10-04 1996-02-27 American Cyanamid Company 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
JP2628230B2 (ja) * 1991-12-30 1997-07-09 エフ エム シー コーポレーション 微結晶性セルローススフェロニゼーション組成物
US5262173A (en) * 1992-03-02 1993-11-16 American Cyanamid Company Pulsatile once-a-day delivery systems for minocycline
CA2093282C (en) * 1992-05-04 1999-01-12 Tibor Sipos Intraoral medicament-releasing device
US5614223A (en) * 1992-05-04 1997-03-25 Digestive Care Inc. Intraoral medicament-releasing device
US6224911B1 (en) * 1993-03-16 2001-05-01 Syntex (U.S.A.) Llc Process for the preparation of enteric coated pharmaceutical dosage forms
US5536507A (en) * 1994-06-24 1996-07-16 Bristol-Myers Squibb Company Colonic drug delivery system
US20060073201A1 (en) * 1996-03-25 2006-04-06 Wyeth Extended release formulation
US20030215507A1 (en) * 1996-03-25 2003-11-20 Wyeth Extended release formulation
US6230052B1 (en) 1999-01-29 2001-05-08 Andy Wolff Device and method for stimulating salivation
WO2000072831A1 (en) * 1999-05-27 2000-12-07 Drugtech Corporation Nutritional formulations
US20050037065A1 (en) * 1999-05-27 2005-02-17 Drugtech Corporation Nutritional formulations
US6858725B1 (en) 1999-11-12 2005-02-22 R.P. Scherer Technologies, Inc. Microcrystalline cellulose cushioning granules
JP2004525955A (ja) * 2001-04-05 2004-08-26 コッラジェネックス ファーマシューチカルス インコーポレイテッド テトラサイクリン化合物およびテトラサイクリン誘導体の制御された伝達
MXPA04006163A (es) * 2001-12-20 2004-11-01 Pharmacia Corp Formas de dosis de liberacion sostenida del orden-cero y metodo de fabricacion de las mismas.
AU2003213876B2 (en) * 2002-04-12 2006-10-12 Mayne Pharma International Pty Ltd An improved modified release preparation
AUPS167602A0 (en) * 2002-04-12 2002-05-16 F.H. Faulding & Co. Limited An improved modified release preparation
US6958161B2 (en) * 2002-04-12 2005-10-25 F H Faulding & Co Limited Modified release coated drug preparation
CA2501324A1 (en) * 2002-10-30 2004-05-21 Pharmacia Corporation Oral extended release tablets and methods of making and using the same
US20040158194A1 (en) * 2003-02-06 2004-08-12 Wolff Andy And Beiski Ben Z. Oral devices and methods for controlled drug release
PL2204168T3 (pl) * 2003-04-07 2015-06-30 Supernus Pharmaceuticals Inc Preparaty tetracyklin do jedorazowego dziennego podawania
GB2414668B (en) * 2004-06-03 2009-07-29 Dexcel Ltd Tetracycline modified release delivery system
NZ556582A (en) * 2005-01-21 2010-12-24 Warner Chilcott Co Llc A tetracycline metal complex in a solid dosage form
ES2557763T3 (es) * 2005-02-04 2016-01-28 Philip Morris Products S.A. Cigarrillo y filtro con adición celulósica de sabor
US20070106138A1 (en) * 2005-05-26 2007-05-10 Beiski Ben Z Intraoral apparatus for non-invasive blood and saliva monitoring & sensing
US9192615B2 (en) * 2008-08-06 2015-11-24 Medicis Pharmaceutical Corporation Method for the treatment of acne and certain dosage forms thereof
US20080241235A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7544373B2 (en) * 2007-04-02 2009-06-09 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7919483B2 (en) * 2005-06-24 2011-04-05 Medicis Pharmaceutical Corporation Method for the treatment of acne
US8252776B2 (en) 2007-04-02 2012-08-28 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US20080242642A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US8722650B1 (en) 2005-06-24 2014-05-13 Medicis Pharmaceutical Corporation Extended-release minocycline dosage forms
US7541347B2 (en) * 2007-04-02 2009-06-02 Medicis Pharmaceutical Coropration Minocycline oral dosage forms for the treatment of acne
CN101340895A (zh) * 2005-12-22 2009-01-07 惠氏公司 包含替加环素的口服制剂
US20070166273A1 (en) * 2006-01-19 2007-07-19 Krivulka Joseph J Skin treatment educational kit
JP5527921B2 (ja) * 2006-12-22 2014-06-25 エスエス製薬株式会社 苦味を隠蔽した経口固形組成物
ITMI20070022A1 (it) 2007-01-09 2008-07-10 I P S Internat Products & Services Srl Formulazione di prodotti solidi a rilascio controllato per uso orale in bustine monodose e relativo procedimento di preparazione
EP2125018A1 (en) * 2007-03-23 2009-12-02 Molecular Research Center, Inc. Compositions and methods for anti-inflammatory treatments
US20080241197A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline dosage forms for the treatment of acne
PT2271348T (pt) * 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
US9561241B1 (en) 2011-06-28 2017-02-07 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for minocycline
US20150011549A1 (en) * 2012-02-15 2015-01-08 Takeda Pharmaceutical Company Limited Tablet
HRP20192227T1 (hr) 2013-03-15 2020-02-21 Braintree Laboratories, Inc. Dvojna uporaba oralnog farmaceutskog pripravka tableta sulfatnih soli i metode njihove uporabe
US20170182070A1 (en) 2014-10-08 2017-06-29 Mayne Pharma International Pty Ltd. Controlled Release Doxycycline
WO2016162754A1 (en) 2015-04-07 2016-10-13 Dr. Reddy's Laboratories Ltd. Pharmaceutical compositions for minocycline
IL273038B (en) 2020-03-03 2022-02-01 Ben Zion Karmon bone graft

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3148212A (en) * 1961-12-22 1964-09-08 American Cyanamid Co Reductive alkylation process
USRE26253E (en) * 1963-05-17 1967-08-15 And z-alkylamino-g-deoxytetracycline
US3356571A (en) * 1964-11-25 1967-12-05 American Cyanamid Co Potentiation of tetracycline by polyacrylic acid or hydrolyzed polyacrylonitrile
CH434240A (de) * 1965-12-30 1967-04-30 Chemical And Pharmaceutical Pa Verfahren zur Herstellung einer therapeutischen Tetracyclinzubereitung mit verlängerter therapeutischer Wirkung
CH434571A (de) * 1966-07-05 1967-04-30 Chemical And Pharmaceutical Pa Verfahren zur Herstellung von Antibiotika mit verlängerter therapeutischer Wirkung
IT1050353B (it) * 1966-01-06 1981-03-10 Ceskoslovenska Akademie Ved Supporti per sostanze biologigamente attive
US4207258A (en) * 1972-02-24 1980-06-10 Ankerfarm S.P.A. Process for the preparatin of α-6-deoxytetracyclines
FR2183546B1 (cs) * 1972-05-10 1975-06-20 Servier Lab
US4038315A (en) * 1972-05-11 1977-07-26 American Cyanamid Company Isolation and recovery of calcium chloride complex of 7-dimethylamino-6-dimethyl l-6-deoxytetracycline hydrochloride
CH582002A5 (cs) * 1972-06-09 1976-11-30 Purdue Research Foundation
CA999855A (en) * 1972-09-18 1976-11-16 Societa' Farmaceutici Italia S.P.A. Process for the preparation of tetracyclines derivatives in the 7 position
JPS4941522A (cs) * 1973-05-17 1974-04-18
GB1413186A (en) * 1973-06-27 1975-11-12 Toyo Jozo Kk Process for encapsulation of medicaments
US4088798A (en) * 1975-11-11 1978-05-09 Sandoz, Inc. Methods for the preparation of controlled gastric residence time medicament formulations
US4154827A (en) * 1977-12-15 1979-05-15 University Of Pennsylvania Inhibition of ADH-stimulated osmotic water flow and aldosterone-stimulated sodium transport
GB2042888B (en) * 1979-03-05 1983-09-28 Teijin Ltd Preparation for administration to the mucosa of the oral or nasal cavity
US4622244A (en) * 1979-09-04 1986-11-11 The Washington University Process for preparation of microcapsules
ES8307096A1 (es) * 1981-06-01 1983-07-01 Orion Yhtymae Oy "un metodo para preparar tabletas a base de polvos de medicamento acidicos, inocuas para el esofago".
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
US4500458A (en) * 1982-01-19 1985-02-19 Plurichemie Anstalt Process for the preparation of α-6-deoxytetracyclines
US4701320A (en) * 1984-11-29 1987-10-20 Lederle (Japan), Ltd. Composition stably containing minocycline for treating periodontal diseases

Also Published As

Publication number Publication date
DE3853566D1 (de) 1995-05-18
GR3015767T3 (en) 1995-07-31
DE3853566T2 (de) 1996-01-11
SK278567B6 (en) 1997-10-08
EP0310814A3 (en) 1989-05-03
NO884408D0 (no) 1988-10-05
AU2344488A (en) 1989-04-06
NZ226396A (en) 1991-08-27
EP0310814B1 (en) 1995-04-12
ATE120957T1 (de) 1995-04-15
EP0310814A2 (en) 1989-04-12
SK656388A3 (en) 1997-10-08
HU202110B (en) 1991-02-28
PT88664B (pt) 2003-06-30
FI884575L (fi) 1989-04-07
CA1338439C (en) 1996-07-09
NO175619C (no) 1994-11-09
CZ279809B6 (cs) 1995-07-12
FI97862C (fi) 1997-03-10
DK175578B1 (da) 2004-12-13
JP2771189B2 (ja) 1998-07-02
NO175619B (cs) 1994-08-01
IL87699A0 (en) 1989-02-28
CZ656388A3 (en) 1995-02-15
IL87699A (en) 1994-06-24
PT88664A (pt) 1989-07-31
DK556788D0 (da) 1988-10-05
FI97862B (fi) 1996-11-29
US4837030A (en) 1989-06-06
NO884408L (no) 1989-04-07
AR243077A1 (es) 1993-07-30
ES2070837T3 (es) 1995-06-16
FI884575A0 (fi) 1988-10-05
PH27236A (en) 1993-05-04
AU609525B2 (en) 1991-05-02
PL275089A1 (en) 1989-07-10
HUT50046A (en) 1989-12-28
ZA887478B (en) 1989-06-28
KR890006242A (ko) 1989-06-12
KR970007902B1 (ko) 1997-05-17
JPH01128929A (ja) 1989-05-22
DK556788A (da) 1989-04-07

Similar Documents

Publication Publication Date Title
EP0310814B1 (en) Novel controlled release formulations of tetracycline compounds
HK1000313B (en) Novel controlled release formulations of tetracycline compounds
CA2025703C (en) Pulsatile once-a-day delivery systems for minocycline
EP0558913B1 (en) Improved pulsatile once-a-day delivery systems for minocycline
EP0418597A2 (en) Controlled release carbonic anhydrase inhibitor containing pharmaceutical compositions from spherical granules in capsule oral dosage unit form
FI96481C (fi) Menetelmä pulssittaisten kerran päivässä annettavien minosykliinin vapautussysteemien valmistamiseksi
HK1009930B (en) Improved pulsatile once-a-day delivery systems for minocycline
NO177553B (no) Fremgangsmåte for fremstilling av et farmasöytisk doseringssystem
NO177554B (no) Fremgangsmåte for fremstilling av en multiovertrukket sammensetning som utgjör et farmasöytisk doseringssystem

Legal Events

Date Code Title Description
PF Patent in force
PE Patent expired

Effective date: 20080831