GR950300047T1 - Method and reagent for determining specific nucleotide variations. - Google Patents

Method and reagent for determining specific nucleotide variations.

Info

Publication number
GR950300047T1
GR950300047T1 GR950300047T GR950300047T GR950300047T1 GR 950300047 T1 GR950300047 T1 GR 950300047T1 GR 950300047 T GR950300047 T GR 950300047T GR 950300047 T GR950300047 T GR 950300047T GR 950300047 T1 GR950300047 T1 GR 950300047T1
Authority
GR
Greece
Prior art keywords
detection step
incorporation
variable nucleotide
reagent
primer
Prior art date
Application number
GR950300047T
Other languages
English (en)
Inventor
Hans Soederlund
Ann-Christine Syvaenen
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of GR950300047T1 publication Critical patent/GR950300047T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • AIDS & HIV (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
GR950300047T 1990-02-16 1995-07-31 Method and reagent for determining specific nucleotide variations. GR950300047T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48200590A 1990-02-16 1990-02-16
PCT/FI1991/000046 WO1991013075A2 (en) 1990-02-16 1991-02-15 Method and reagent for determining specific nucleotide variations

Publications (1)

Publication Number Publication Date
GR950300047T1 true GR950300047T1 (en) 1995-07-31

Family

ID=23914258

Family Applications (2)

Application Number Title Priority Date Filing Date
GR950300047T GR950300047T1 (en) 1990-02-16 1995-07-31 Method and reagent for determining specific nucleotide variations.
GR990401879T GR3030790T3 (en) 1990-02-16 1999-07-14 Method and reagent for determining specific nucleotide variations.

Family Applications After (1)

Application Number Title Priority Date Filing Date
GR990401879T GR3030790T3 (en) 1990-02-16 1999-07-14 Method and reagent for determining specific nucleotide variations.

Country Status (18)

Country Link
EP (1) EP0648280B1 (el)
JP (1) JP2786011B2 (el)
AT (1) ATE180019T1 (el)
AU (1) AU642709B2 (el)
CA (1) CA2071537C (el)
DE (2) DE648280T1 (el)
DK (1) DK0648280T3 (el)
ES (1) ES2072235T3 (el)
FI (1) FI102297B (el)
GR (2) GR950300047T1 (el)
HU (1) HU211058B (el)
IE (1) IE910525A1 (el)
IL (1) IL97222A (el)
NO (1) NO311529B1 (el)
NZ (1) NZ237134A (el)
PT (1) PT96776B (el)
WO (1) WO1991013075A2 (el)
ZA (1) ZA911152B (el)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5547839A (en) 1989-06-07 1996-08-20 Affymax Technologies N.V. Sequencing of surface immobilized polymers utilizing microflourescence detection
US6013431A (en) 1990-02-16 2000-01-11 Molecular Tool, Inc. Method for determining specific nucleotide variations by primer extension in the presence of mixture of labeled nucleotides and terminators
US6004744A (en) * 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
AU1741692A (en) * 1991-03-13 1992-10-21 Regents Of The University Of California, The Detection of 3'-azido-3'-deoxythymidine resistance
US20100267023A1 (en) 1992-09-24 2010-10-21 Keygene N.V. Selective restriction fragment amplification: fingerprinting
US7026115B1 (en) 1991-09-24 2006-04-11 Keygene N.V. Selective restriction fragment amplification: fingerprinting
GB9208000D0 (en) * 1992-04-10 1992-05-27 Univ London Quantitative viral assay
WO1993022457A1 (en) * 1992-04-24 1993-11-11 Massachusetts Institute Of Technology Screening for genetic variation
JP2001507921A (ja) * 1992-04-27 2001-06-19 トラスティーズ オブ ダートマス カレッジ 生物学的液体中の遺伝子配列の検出
GB9210176D0 (en) † 1992-05-12 1992-06-24 Cemu Bioteknik Ab Chemical method
EP0607151B1 (en) * 1992-06-17 2002-11-13 City Of Hope A method of detecting and discriminating between nucleic acid sequences
US5981176A (en) 1992-06-17 1999-11-09 City Of Hope Method of detecting and discriminating between nucleic acid sequences
DE69232846T2 (de) * 1992-06-17 2003-08-21 City Of Hope Duarte Verfahren zum nachweis und unterscheiden von nukleinsäuresequenzen
ES2191666T3 (es) * 1992-07-02 2003-09-16 Pronto Diagnostics Ltd Metodos de alargamiento de cebo de nucleotido simple para detectar alelos especificos y kit apropiado para ello.
US5710028A (en) * 1992-07-02 1998-01-20 Eyal; Nurit Method of quick screening and identification of specific DNA sequences by single nucleotide primer extension and kits therefor
US5605798A (en) 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
US7001722B1 (en) 1993-06-22 2006-02-21 Baylor College Of Medicine Parallel primer extension approach to nucleic acid sequence analysis
US6153379A (en) * 1993-06-22 2000-11-28 Baylor College Of Medicine Parallel primer extension approach to nucleic acid sequence analysis
US6071699A (en) 1996-06-07 2000-06-06 California Institute Of Technology Nucleic acid mediated electron transfer
CA2111503A1 (en) * 1993-12-15 1995-06-16 Mcgill University Apolipoprotein e polymorphism and alzheimer's disease
US6428955B1 (en) 1995-03-17 2002-08-06 Sequenom, Inc. DNA diagnostics based on mass spectrometry
GB9507238D0 (en) 1995-04-07 1995-05-31 Isis Innovation Detecting dna sequence variations
GB9517914D0 (en) * 1995-09-02 1995-11-01 Tepnel Medical Ltd Identification of bases in nucleic acid sequences
NO954667D0 (no) * 1995-11-17 1995-11-17 Dagfinn Oegreid Fremgangsmåte til deteksjon av Ki-ras mutasjoner
WO1997035033A1 (en) 1996-03-19 1997-09-25 Molecular Tool, Inc. Method for determining the nucleotide sequence of a polynucleotide
EP0933431A1 (en) * 1996-07-11 1999-08-04 Wakunaga Pharmaceutical Co., Ltd. Method for examining nucleic acids and examination kits
EP0942917B1 (en) 1996-08-14 2015-02-25 Life Technologies Corporation Method for nucleic acid amplification and sequencing using stable compositions
GB9620209D0 (en) 1996-09-27 1996-11-13 Cemu Bioteknik Ab Method of sequencing DNA
US7381525B1 (en) 1997-03-07 2008-06-03 Clinical Micro Sensors, Inc. AC/DC voltage apparatus for detection of nucleic acids
US7045285B1 (en) 1996-11-05 2006-05-16 Clinical Micro Sensors, Inc. Electronic transfer moieties attached to peptide nucleic acids
US6140053A (en) 1996-11-06 2000-10-31 Sequenom, Inc. DNA sequencing by mass spectrometry via exonuclease degradation
US6133436A (en) * 1996-11-06 2000-10-17 Sequenom, Inc. Beads bound to a solid support and to nucleic acids
GB9626815D0 (en) 1996-12-23 1997-02-12 Cemu Bioteknik Ab Method of sequencing DNA
US6309829B1 (en) 1997-05-27 2001-10-30 Pe Corporation (Ny) Length determination of nucleic acid repeat sequences by discontinuous primer extension
US5945284A (en) * 1997-05-27 1999-08-31 The Perkin-Elmer Corporation Length determination of nucleic acid repeat sequences by discontinuous primer extension
US5888778A (en) * 1997-06-16 1999-03-30 Exact Laboratories, Inc. High-throughput screening method for identification of genetic mutations or disease-causing microorganisms using segmented primers
US6566101B1 (en) 1997-06-16 2003-05-20 Anthony P. Shuber Primer extension methods for detecting nucleic acids
US7105353B2 (en) 1997-07-18 2006-09-12 Serono Genetics Institute S.A. Methods of identifying individuals for inclusion in drug studies
GB9715034D0 (en) * 1997-07-18 1997-09-24 Zeneca Ltd Assay
EP0892068A1 (en) * 1997-07-18 1999-01-20 Genset Sa Method for generating a high density linkage disequilibrium-based map of the human genome
US7745142B2 (en) 1997-09-15 2010-06-29 Molecular Devices Corporation Molecular modification assays
US6537751B1 (en) 1998-04-21 2003-03-25 Genset S.A. Biallelic markers for use in constructing a high density disequilibrium map of the human genome
CA2245039A1 (en) 1998-08-13 2000-02-13 Vito Scalia Primer-specific and mispair extension assay for identifying gene variation
EP1108065A1 (en) * 1998-08-28 2001-06-20 Sangtec Molecular Diagnostics AB A method for measuring a patient's ability to metabolise certain drugs
DE19855469C2 (de) * 1998-12-01 2001-01-11 Michael Esrich Verfahren zur Bestimmung des Apolipoprotein-E-Genotyps in einer menschlichen Probe
US6503718B2 (en) 1999-01-10 2003-01-07 Exact Sciences Corporation Methods for detecting mutations using primer extension for detecting disease
US6280947B1 (en) 1999-08-11 2001-08-28 Exact Sciences Corporation Methods for detecting nucleotide insertion or deletion using primer extension
US6573047B1 (en) 1999-04-13 2003-06-03 Dna Sciences, Inc. Detection of nucleotide sequence variation through fluorescence resonance energy transfer label generation
US20060275782A1 (en) 1999-04-20 2006-12-07 Illumina, Inc. Detection of nucleic acid reactions on bead arrays
CA2370976C (en) 1999-04-20 2009-10-20 Illumina, Inc. Detection of nucleic acid reactions on bead arrays
US7056661B2 (en) 1999-05-19 2006-06-06 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
JP2001245698A (ja) * 1999-11-22 2001-09-11 Xiao Bing Wang 核酸検出法
IL149676A0 (en) 1999-12-02 2002-11-10 Dna Sciences Inc Methods and kits for determining nucleotide variations
US6518024B2 (en) 1999-12-13 2003-02-11 Motorola, Inc. Electrochemical detection of single base extension
US6762018B1 (en) * 1999-12-23 2004-07-13 Tetragen Sa Analysis of nucleotide polymorphisms at a site
AU3838901A (en) 2000-02-16 2001-08-27 Illumina Inc Parallel genotyping of multiple patient samples
US6355433B1 (en) 2000-06-02 2002-03-12 Dna Sciences, Inc. Determination of nucleotide sequence variations through limited primer extension
SG115374A1 (en) * 2000-07-17 2005-10-28 Xiao Bing Wang Detection of sequence variation of nucleic acid by shifted termination analysis
CH699253B1 (de) * 2000-09-18 2010-02-15 Eidgenoessische Forschungsanst Verfahren zur Charakterisierung und/oder Identifikation von Genomen.
AU2002227156A1 (en) 2000-12-01 2002-06-11 Visigen Biotechnologies, Inc. Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
US6428964B1 (en) 2001-03-15 2002-08-06 Exact Sciences Corporation Method for alteration detection
US6803201B2 (en) 2002-01-24 2004-10-12 Stratagene Compositions and methods for polynucleotide sequence determination
JP4143756B2 (ja) * 2002-06-21 2008-09-03 財団法人名古屋産業科学研究所 心筋梗塞のリスク診断方法
DE10245145B4 (de) * 2002-09-27 2004-12-02 IPK-Institut für Pflanzengenetik und Kulturpflanzenforschung Verfahren zum Nachweis von SNPs auf polydimensionalen Microarrays
US7803579B2 (en) 2002-10-29 2010-09-28 Riken Process for amplifying nucleic acid
TW201037080A (en) 2003-12-25 2010-10-16 Danform Kk Method of amplifying nucleic acid and method of detecting mutated nucleic acid using the same
JP2008513782A (ja) 2004-09-17 2008-05-01 パシフィック バイオサイエンシーズ オブ カリフォルニア， インコーポレイテッド 分子解析のための装置及び方法
US7170050B2 (en) 2004-09-17 2007-01-30 Pacific Biosciences Of California, Inc. Apparatus and methods for optical analysis of molecules
WO2006047787A2 (en) 2004-10-27 2006-05-04 Exact Sciences Corporation Method for monitoring disease progression or recurrence
US9777314B2 (en) 2005-04-21 2017-10-03 Esoterix Genetic Laboratories, Llc Analysis of heterogeneous nucleic acid samples
EP3425060B1 (en) 2008-03-28 2021-10-27 Pacific Biosciences of California, Inc. Compositions and methods for nucleic acid sequencing
WO2012049279A1 (en) 2010-10-14 2012-04-19 Universitaet Des Saarlandes MEANS AND METHODS APPLYING SINGLE NUCLEOTIDE PRIMER EXTENSION WITH ION PAIR-, REVERSED-PHASE HPLC (SIRPH) FOR THE DIAGNOSIS OF SNPs

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8311018D0 (en) * 1983-04-22 1983-05-25 Amersham Int Plc Detecting mutations in dna
US4851331A (en) * 1986-05-16 1989-07-25 Allied Corporation Method and kit for polynucleotide assay including primer-dependant DNA polymerase
AU622104B2 (en) * 1987-03-11 1992-04-02 Sangtec Molecular Diagnostics Ab Method of assaying of nucleic acids, a reagent combination and kit therefore
FI80476C (fi) * 1987-10-09 1990-06-11 Orion Yhtymae Oy Foerbaettrat hybridisationsfoerfarande, vid foerfarandet anvaent redskap och reagensfoerpackning.
IE61148B1 (en) * 1988-03-10 1994-10-05 Ici Plc Method of detecting nucleotide sequences
CA1338526C (en) * 1988-03-18 1996-08-20 Charles Thomas Caskey Mutation detection by competitive oligonucleotide priming
AU3539089A (en) * 1988-04-08 1989-11-03 Salk Institute For Biological Studies, The Ligase-based amplification method
AU3694689A (en) * 1988-04-28 1989-11-24 Mark H. Skolnick Amplified sequence polymorphisms (asps)
AU629845B2 (en) * 1988-08-30 1992-10-15 Abbott Laboratories Detection and amplification of target nucleic acid sequences
CA2002076A1 (en) * 1988-11-21 1990-05-21 Brent A. Burdick Diagnostic kit and method using a solid phase capture means for detecting nucleic acids
IL92474A (en) * 1988-11-29 1994-04-12 Orion Yhtymae Oy Reaction method and combination for determining nucleotide sequences
WO1990009455A1 (en) * 1989-02-13 1990-08-23 Geneco Pty Ltd Detection of a nucleic acid sequence or a change therein
AU5640090A (en) * 1989-03-21 1990-11-05 Collaborative Research Inc. A dna diagnostic test using an exonuclease activity

Also Published As

Publication number Publication date
NO311529B1 (no) 2001-12-03
AU642709B2 (en) 1993-10-28
FI923653A (fi) 1992-08-14
WO1991013075A3 (en) 1991-10-17
FI102297B1 (fi) 1998-11-13
FI923653A0 (fi) 1992-08-14
FI102297B (fi) 1998-11-13
HU910516D0 (en) 1991-09-30
IL97222A0 (en) 1992-05-25
DE648280T1 (de) 1995-11-30
GR3030790T3 (en) 1999-11-30
DE69131233D1 (de) 1999-06-17
PT96776B (pt) 1998-05-29
IE910525A1 (en) 1991-08-28
JP2786011B2 (ja) 1998-08-13
EP0648280A1 (en) 1995-04-19
WO1991013075A2 (en) 1991-09-05
AU7235191A (en) 1991-09-18
JPH05504477A (ja) 1993-07-15
ES2072235T3 (es) 1999-07-16
DK0648280T3 (da) 1999-11-01
ES2072235T1 (es) 1995-07-16
IL97222A (en) 1995-08-31
CA2071537A1 (en) 1991-08-17
PT96776A (pt) 1991-10-31
CA2071537C (en) 2003-02-11
NO923116L (no) 1992-08-10
DE69131233T2 (de) 1999-11-04
HU211058B (en) 1995-10-30
ATE180019T1 (de) 1999-05-15
ZA911152B (en) 1991-11-27
EP0648280B1 (en) 1999-05-12
HUT61330A (en) 1992-12-28
NO923116D0 (no) 1992-08-10
NZ237134A (en) 1992-06-25

Similar Documents

Publication Publication Date Title
ZA911152B (en) Method and reagent for determining specific nucleotide variations
BR8901136A (pt) Processo para detectar a presenca ou ausencia de pelo menos um nucleotidio variante em um ou mais acidos nucleicos,sequencia de nucleotideos para uso no processo e estojo para realizar a dita deteccao
DE68908900T2 (de) Nachweis und bestimmung der menge an rns und dns.
ATE142272T1 (de) Nukleinsäure-amplifikation unter verwendung eines einzelprimers
IE900442L (en) Assay method for nucleic acid sequence
DE69029726T2 (de) Festphasendiagnose von medizinischen konditionen
DE3474305D1 (en) Probe containing a modified nucleic acid recognizable by specific antibodies and the use to detect and characterize a homologous dna sequence
FI904494A0 (fi) Diagnos- och amplifieringsfoerfaranden foer eliminering av ett primer-maol-opar i primerns 3'-aenda.
CA2303414A1 (en) Non-competitive co-amplification methods
FI946127A (fi) Menetelmä alukkeen pidentämiseksi yhdellä nukleotidilla spesifisten alleelien detektoimiseksi, ja testipakkaus näiden menetelmien suorittamiseksi
DK0443823T3 (da) Mængdebestemmelse af en DNA-polymerase og et testsæt dertil
WO1998014611A3 (en) Detection and identification of non-polio enteroviruses
ES2082881T3 (es) Procedimiento para la deteccion y determinacion cuantitativa de cepas de nitrosomonas en aguas residuales o suelos.
WO1998000565A3 (en) NUCLEIC ACID PRIMERS AND PROBES FOR DETECTING $i(MYCOPLASMA PNEUMONIAE)
ES2178769T3 (es) Sonda, secuencias nucleicas y procedimiento principalmente, de deteccion y de identificacion de levaduras, al igual que los utiles correspondientes.