FI923653A - Foerfarande och reagens foer bestaemning av specifika nukleotidvariationer. - Google Patents

Foerfarande och reagens foer bestaemning av specifika nukleotidvariationer. Download PDF

Info

Publication number
FI923653A
FI923653A FI923653A FI923653A FI923653A FI 923653 A FI923653 A FI 923653A FI 923653 A FI923653 A FI 923653A FI 923653 A FI923653 A FI 923653A FI 923653 A FI923653 A FI 923653A
Authority
FI
Finland
Prior art keywords
detection step
variation
incorporation
variable nucleotide
nucleotid
Prior art date
Application number
FI923653A
Other languages
English (en)
Other versions
FI923653A0 (fi
FI102297B (fi
FI102297B1 (fi
Inventor
Hans Erik Soederlund
Ann-Christine Elisabe Syvaenen
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of FI923653A0 publication Critical patent/FI923653A0/fi
Publication of FI923653A publication Critical patent/FI923653A/fi
Application granted granted Critical
Publication of FI102297B publication Critical patent/FI102297B/fi
Publication of FI102297B1 publication Critical patent/FI102297B1/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI923653A 1990-02-16 1992-08-14 Menetelmä ja reagenssi spesifisten nukleotidivariaatioiden määrittämiseksi FI102297B1 (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US48200590A 1990-02-16 1990-02-16
US48200590 1990-02-16
PCT/FI1991/000046 WO1991013075A2 (en) 1990-02-16 1991-02-15 Method and reagent for determining specific nucleotide variations
FI9100046 1991-02-15

Publications (4)

Publication Number Publication Date
FI923653A0 FI923653A0 (fi) 1992-08-14
FI923653A true FI923653A (fi) 1992-08-14
FI102297B FI102297B (fi) 1998-11-13
FI102297B1 FI102297B1 (fi) 1998-11-13

Family

ID=23914258

Family Applications (1)

Application Number Title Priority Date Filing Date
FI923653A FI102297B1 (fi) 1990-02-16 1992-08-14 Menetelmä ja reagenssi spesifisten nukleotidivariaatioiden määrittämiseksi

Country Status (18)

Country Link
EP (1) EP0648280B1 (fi)
JP (1) JP2786011B2 (fi)
AT (1) ATE180019T1 (fi)
AU (1) AU642709B2 (fi)
CA (1) CA2071537C (fi)
DE (2) DE69131233T2 (fi)
DK (1) DK0648280T3 (fi)
ES (1) ES2072235T3 (fi)
FI (1) FI102297B1 (fi)
GR (2) GR950300047T1 (fi)
HU (1) HU211058B (fi)
IE (1) IE910525A1 (fi)
IL (1) IL97222A (fi)
NO (1) NO311529B1 (fi)
NZ (1) NZ237134A (fi)
PT (1) PT96776B (fi)
WO (1) WO1991013075A2 (fi)
ZA (1) ZA911152B (fi)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5547839A (en) 1989-06-07 1996-08-20 Affymax Technologies N.V. Sequencing of surface immobilized polymers utilizing microflourescence detection
US6013431A (en) 1990-02-16 2000-01-11 Molecular Tool, Inc. Method for determining specific nucleotide variations by primer extension in the presence of mixture of labeled nucleotides and terminators
US6004744A (en) * 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
AU1741692A (en) * 1991-03-13 1992-10-21 Regents Of The University Of California, The Detection of 3'-azido-3'-deoxythymidine resistance
US20100267023A1 (en) 1992-09-24 2010-10-21 Keygene N.V. Selective restriction fragment amplification: fingerprinting
US7026115B1 (en) 1991-09-24 2006-04-11 Keygene N.V. Selective restriction fragment amplification: fingerprinting
GB9208000D0 (en) * 1992-04-10 1992-05-27 Univ London Quantitative viral assay
US5750335A (en) * 1992-04-24 1998-05-12 Massachusetts Institute Of Technology Screening for genetic variation
CA2134552A1 (en) * 1992-04-27 1993-11-11 George D. Sorenson Detection of gene sequences in biological fluids
GB9210176D0 (en) * 1992-05-12 1992-06-24 Cemu Bioteknik Ab Chemical method
EP0607151B1 (en) * 1992-06-17 2002-11-13 City Of Hope A method of detecting and discriminating between nucleic acid sequences
US5981176A (en) 1992-06-17 1999-11-09 City Of Hope Method of detecting and discriminating between nucleic acid sequences
DE69232846T2 (de) * 1992-06-17 2003-08-21 City Of Hope, Duarte Verfahren zum nachweis und unterscheiden von nukleinsäuresequenzen
EP0648222B1 (en) * 1992-07-02 2003-01-29 Savyon Diagnostics Ltd. Methods of single nucleotide primer extension to detect specific alleles and kits therefor
US5710028A (en) * 1992-07-02 1998-01-20 Eyal; Nurit Method of quick screening and identification of specific DNA sequences by single nucleotide primer extension and kits therefor
US5605798A (en) 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
US6153379A (en) * 1993-06-22 2000-11-28 Baylor College Of Medicine Parallel primer extension approach to nucleic acid sequence analysis
US7001722B1 (en) 1993-06-22 2006-02-21 Baylor College Of Medicine Parallel primer extension approach to nucleic acid sequence analysis
US6071699A (en) 1996-06-07 2000-06-06 California Institute Of Technology Nucleic acid mediated electron transfer
CA2111503A1 (en) * 1993-12-15 1995-06-16 Mcgill University Apolipoprotein e polymorphism and alzheimer's disease
US6428955B1 (en) 1995-03-17 2002-08-06 Sequenom, Inc. DNA diagnostics based on mass spectrometry
GB9507238D0 (en) 1995-04-07 1995-05-31 Isis Innovation Detecting dna sequence variations
GB9517914D0 (en) * 1995-09-02 1995-11-01 Tepnel Medical Ltd Identification of bases in nucleic acid sequences
NO954667D0 (no) * 1995-11-17 1995-11-17 Dagfinn Oegreid Fremgangsmåte til deteksjon av Ki-ras mutasjoner
WO1997035033A1 (en) 1996-03-19 1997-09-25 Molecular Tool, Inc. Method for determining the nucleotide sequence of a polynucleotide
CA2260362A1 (en) * 1996-07-11 1998-01-22 Takanori Oka Nucleic acid assay process and assay kit
AU4065397A (en) 1996-08-14 1998-03-06 Life Technologies, Inc. Stable compositions for nucleic acid amplification and sequencing
GB9620209D0 (en) 1996-09-27 1996-11-13 Cemu Bioteknik Ab Method of sequencing DNA
US7381525B1 (en) 1997-03-07 2008-06-03 Clinical Micro Sensors, Inc. AC/DC voltage apparatus for detection of nucleic acids
US7045285B1 (en) 1996-11-05 2006-05-16 Clinical Micro Sensors, Inc. Electronic transfer moieties attached to peptide nucleic acids
US6133436A (en) * 1996-11-06 2000-10-17 Sequenom, Inc. Beads bound to a solid support and to nucleic acids
US6140053A (en) 1996-11-06 2000-10-31 Sequenom, Inc. DNA sequencing by mass spectrometry via exonuclease degradation
GB9626815D0 (en) 1996-12-23 1997-02-12 Cemu Bioteknik Ab Method of sequencing DNA
US5945284A (en) * 1997-05-27 1999-08-31 The Perkin-Elmer Corporation Length determination of nucleic acid repeat sequences by discontinuous primer extension
US6309829B1 (en) 1997-05-27 2001-10-30 Pe Corporation (Ny) Length determination of nucleic acid repeat sequences by discontinuous primer extension
US6566101B1 (en) 1997-06-16 2003-05-20 Anthony P. Shuber Primer extension methods for detecting nucleic acids
US5888778A (en) * 1997-06-16 1999-03-30 Exact Laboratories, Inc. High-throughput screening method for identification of genetic mutations or disease-causing microorganisms using segmented primers
US7105353B2 (en) 1997-07-18 2006-09-12 Serono Genetics Institute S.A. Methods of identifying individuals for inclusion in drug studies
GB9715034D0 (en) * 1997-07-18 1997-09-24 Zeneca Ltd Assay
EP0892068A1 (en) * 1997-07-18 1999-01-20 Genset Sa Method for generating a high density linkage disequilibrium-based map of the human genome
US7745142B2 (en) 1997-09-15 2010-06-29 Molecular Devices Corporation Molecular modification assays
US6537751B1 (en) 1998-04-21 2003-03-25 Genset S.A. Biallelic markers for use in constructing a high density disequilibrium map of the human genome
CA2245039A1 (en) * 1998-08-13 2000-02-13 Vito Scalia Primer-specific and mispair extension assay for identifying gene variation
EP1108065A1 (en) * 1998-08-28 2001-06-20 Sangtec Molecular Diagnostics AB A method for measuring a patient's ability to metabolise certain drugs
DE19855469C2 (de) * 1998-12-01 2001-01-11 Michael Esrich Verfahren zur Bestimmung des Apolipoprotein-E-Genotyps in einer menschlichen Probe
US6503718B2 (en) 1999-01-10 2003-01-07 Exact Sciences Corporation Methods for detecting mutations using primer extension for detecting disease
US6280947B1 (en) 1999-08-11 2001-08-28 Exact Sciences Corporation Methods for detecting nucleotide insertion or deletion using primer extension
US6573047B1 (en) 1999-04-13 2003-06-03 Dna Sciences, Inc. Detection of nucleotide sequence variation through fluorescence resonance energy transfer label generation
WO2000063437A2 (en) 1999-04-20 2000-10-26 Illumina, Inc. Detection of nucleic acid reactions on bead arrays
US20060275782A1 (en) 1999-04-20 2006-12-07 Illumina, Inc. Detection of nucleic acid reactions on bead arrays
US7056661B2 (en) 1999-05-19 2006-06-06 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
JP2001245698A (ja) * 1999-11-22 2001-09-11 Xiao Bing Wang 核酸検出法
JP2003517309A (ja) 1999-12-02 2003-05-27 ディーエヌエー サイエンシーズ インコーポレーテッド 単一ヌクレオチドの変異及びジェノタイピングの決定方法
US6518024B2 (en) 1999-12-13 2003-02-11 Motorola, Inc. Electrochemical detection of single base extension
US6762018B1 (en) 1999-12-23 2004-07-13 Tetragen Sa Analysis of nucleotide polymorphisms at a site
EP1967595A3 (en) 2000-02-16 2008-12-03 Illumina, Inc. Parallel genotyping of multiple patient samples
US6355433B1 (en) 2000-06-02 2002-03-12 Dna Sciences, Inc. Determination of nucleotide sequence variations through limited primer extension
SG115374A1 (en) * 2000-07-17 2005-10-28 Xiao Bing Wang Detection of sequence variation of nucleic acid by shifted termination analysis
CH699253B1 (de) * 2000-09-18 2010-02-15 Eidgenoessische Forschungsanst Verfahren zur Charakterisierung und/oder Identifikation von Genomen.
WO2002044425A2 (en) 2000-12-01 2002-06-06 Visigen Biotechnologies, Inc. Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
US6428964B1 (en) 2001-03-15 2002-08-06 Exact Sciences Corporation Method for alteration detection
US6803201B2 (en) 2002-01-24 2004-10-12 Stratagene Compositions and methods for polynucleotide sequence determination
JP4143756B2 (ja) 2002-06-21 2008-09-03 財団法人名古屋産業科学研究所 心筋梗塞のリスク診断方法
DE10245145B4 (de) * 2002-09-27 2004-12-02 IPK-Institut für Pflanzengenetik und Kulturpflanzenforschung Verfahren zum Nachweis von SNPs auf polydimensionalen Microarrays
US7803579B2 (en) 2002-10-29 2010-09-28 Riken Process for amplifying nucleic acid
US8206902B2 (en) 2003-12-25 2012-06-26 Riken Method of amplifying nucleic acid and method of detecting mutated nucleic acid using the same
US7170050B2 (en) 2004-09-17 2007-01-30 Pacific Biosciences Of California, Inc. Apparatus and methods for optical analysis of molecules
EP3415641B1 (en) 2004-09-17 2023-11-01 Pacific Biosciences Of California, Inc. Method for analysis of molecules
WO2006047787A2 (en) 2004-10-27 2006-05-04 Exact Sciences Corporation Method for monitoring disease progression or recurrence
US9777314B2 (en) 2005-04-21 2017-10-03 Esoterix Genetic Laboratories, Llc Analysis of heterogeneous nucleic acid samples
EP2274449B1 (en) 2008-03-28 2015-12-23 Pacific Biosciences of California, Inc. Methods for nucleic acid sequencing
WO2012049279A1 (en) 2010-10-14 2012-04-19 Universitaet Des Saarlandes MEANS AND METHODS APPLYING SINGLE NUCLEOTIDE PRIMER EXTENSION WITH ION PAIR-, REVERSED-PHASE HPLC (SIRPH) FOR THE DIAGNOSIS OF SNPs

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8311018D0 (en) * 1983-04-22 1983-05-25 Amersham Int Plc Detecting mutations in dna
US4851331A (en) * 1986-05-16 1989-07-25 Allied Corporation Method and kit for polynucleotide assay including primer-dependant DNA polymerase
AU622104B2 (en) * 1987-03-11 1992-04-02 Sangtec Molecular Diagnostics Ab Method of assaying of nucleic acids, a reagent combination and kit therefore
FI80476C (fi) * 1987-10-09 1990-06-11 Orion Yhtymae Oy Foerbaettrat hybridisationsfoerfarande, vid foerfarandet anvaent redskap och reagensfoerpackning.
IE61148B1 (en) * 1988-03-10 1994-10-05 Ici Plc Method of detecting nucleotide sequences
EP0333465B1 (en) * 1988-03-18 1994-07-13 Baylor College Of Medicine Mutation detection by competitive oligonucleotide priming
AU3539089A (en) * 1988-04-08 1989-11-03 Salk Institute For Biological Studies, The Ligase-based amplification method
WO1989010414A1 (en) * 1988-04-28 1989-11-02 Robert Bruce Wallace AMPLIFIED SEQUENCE POLYMORPHISMS (ASPs)
AU629845B2 (en) * 1988-08-30 1992-10-15 Abbott Laboratories Detection and amplification of target nucleic acid sequences
CA2002076A1 (en) * 1988-11-21 1990-05-21 Brent A. Burdick Diagnostic kit and method using a solid phase capture means for detecting nucleic acids
IL92474A (en) * 1988-11-29 1994-04-12 Orion Yhtymae Oy Reaction method and combination for determining nucleotide sequences
DE69033179T3 (de) * 1989-02-13 2005-01-27 Geneco Pty. Ltd. Nachweis einer nukleinsäuresequenz oder einer änderung darin
WO1990012115A1 (en) * 1989-03-21 1990-10-18 Collaborative Research, Inc. A dna diagnostic test using an exonuclease activity

Also Published As

Publication number Publication date
PT96776B (pt) 1998-05-29
NZ237134A (en) 1992-06-25
EP0648280B1 (en) 1999-05-12
WO1991013075A2 (en) 1991-09-05
HU910516D0 (en) 1991-09-30
DE648280T1 (de) 1995-11-30
JPH05504477A (ja) 1993-07-15
FI923653A0 (fi) 1992-08-14
NO311529B1 (no) 2001-12-03
FI102297B (fi) 1998-11-13
GR3030790T3 (en) 1999-11-30
HUT61330A (en) 1992-12-28
AU7235191A (en) 1991-09-18
NO923116D0 (no) 1992-08-10
PT96776A (pt) 1991-10-31
IL97222A0 (en) 1992-05-25
CA2071537A1 (en) 1991-08-17
AU642709B2 (en) 1993-10-28
ZA911152B (en) 1991-11-27
FI102297B1 (fi) 1998-11-13
CA2071537C (en) 2003-02-11
JP2786011B2 (ja) 1998-08-13
DE69131233T2 (de) 1999-11-04
NO923116L (no) 1992-08-10
HU211058B (en) 1995-10-30
ATE180019T1 (de) 1999-05-15
WO1991013075A3 (en) 1991-10-17
EP0648280A1 (en) 1995-04-19
ES2072235T1 (es) 1995-07-16
IL97222A (en) 1995-08-31
DK0648280T3 (da) 1999-11-01
IE910525A1 (en) 1991-08-28
ES2072235T3 (es) 1999-07-16
DE69131233D1 (de) 1999-06-17
GR950300047T1 (en) 1995-07-31

Similar Documents

Publication Publication Date Title
FI923653A (fi) Foerfarande och reagens foer bestaemning av specifika nukleotidvariationer.
BR8901136A (pt) Processo para detectar a presenca ou ausencia de pelo menos um nucleotidio variante em um ou mais acidos nucleicos,sequencia de nucleotideos para uso no processo e estojo para realizar a dita deteccao
WO2004013357A3 (en) Nucleotide sequences specific to francisella tularensis and methods for the detection of francisella tularensis
DE69028325D1 (de) Nukleinsäure-Amplifikation unter Verwendung eines Einzelprimers
DK0457824T4 (da) Detektion af en nukleinsyresekvens eller en ændring deri
DK144886A (da) Fremgangsmaade til multiplikation af en specifik nukleinsyresekvens
DK564089D0 (da) Fremgangsmaade og reagens til paavisning af humant papillomavirus og m-rna
FI946127A0 (fi) Menetelmä alukkeen pidentämiseksi yhdellä nukleotidilla spesifisten alleelien detektoimiseksi, ja testipakkaus näiden menetelmien suorittamiseksi
DK0443823T3 (da) Mængdebestemmelse af en DNA-polymerase og et testsæt dertil
ES2188997T3 (es) Deteccion e identificacion de enterovirus no poliovirus.
WO1998044157A3 (en) Methods for identifying variations in polynucleotide sequences
ATE184055T1 (de) Verfahren zum sensitiven nachweis von reverser transcriptase
EP0810291A4 (en) PROBE FOR USE IN NUCLEIC ACID ANALYSIS AND METHOD OF DETECTION
WO1998000565A3 (en) NUCLEIC ACID PRIMERS AND PROBES FOR DETECTING $i(MYCOPLASMA PNEUMONIAE)
ATE478147T1 (de) Aus einem neuroblastom isolierte nukleinsäuren
WO2002090585A3 (en) Genetic polymorphism pattern of tgfb1 as marker for susceptability to renal disease
WO2004104170A3 (en) Tools for detecting moraxella catarrhalis.
WO2005078129A3 (fr) Procede pour le diagnostic/pronostic d’une thrombose
ES2178769T3 (es) Sonda, secuencias nucleicas y procedimiento principalmente, de deteccion y de identificacion de levaduras, al igual que los utiles correspondientes.

Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: SANGTEC MEDICAL AB

MA Patent expired