DE3134780A1
(de)
*
|
1981-09-02 |
1983-03-10 |
Hoechst Ag, 6000 Frankfurt |
"sulfonylharnstoffe, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung"
|
US4985417A
(en)
*
|
1989-05-02 |
1991-01-15 |
Trager Seymour F |
Treatment of glaucoma
|
JP3465247B2
(ja)
*
|
1992-12-28 |
2003-11-10 |
アベンティス ファーマ株式会社 |
動脈硬化症の予防および治療剤
|
US5631275A
(en)
*
|
1993-12-30 |
1997-05-20 |
Hoechst Aktiengesellschaft |
Substituted benzenesulfonylureas and -thioureas, preparation processes and possible uses of pharmaceutical preparations based on these compounds
|
DE4344957A1
(de)
*
|
1993-12-30 |
1995-07-06 |
Hoechst Ag |
Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Herstellungsverfahren und Verwendungsmöglichkeiten pharmazeutischer Präparate auf Basis dieser Verbindungen
|
AP1224A
(en)
|
1998-03-19 |
2003-11-14 |
Bristol Myers Squibb Co |
Biphasic controlled release delivery system for high solubility pharmaceuticals and method.
|
US6548529B1
(en)
|
1999-04-05 |
2003-04-15 |
Bristol-Myers Squibb Company |
Heterocyclic containing biphenyl aP2 inhibitors and method
|
US6395767B2
(en)
|
2000-03-10 |
2002-05-28 |
Bristol-Myers Squibb Company |
Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
|
AU2001276598A1
(en)
|
2000-08-07 |
2002-02-18 |
Ranbaxy Signature Llc |
Liquid formulation of metformin
|
PE20020617A1
(es)
|
2000-08-22 |
2002-08-05 |
Novartis Ag |
Composicion que comprende un antagonista del receptor at1 y un potenciador de la secrecion de insulina o un sensibilizante a la insulina
|
US6806381B2
(en)
*
|
2001-11-02 |
2004-10-19 |
Bristol-Myers Squibb Company |
Process for the preparation of aniline-derived thyroid receptor ligands
|
AU2003235814A1
(en)
*
|
2002-01-07 |
2003-07-24 |
Sun Pharmaceutical Industries Limited |
Novel process for the preparation of trans-3- ethyl-2,5- dihydro-4- methyl-n-(2-( 4-(((((4-methyl cyclohexyl) amino)carbonyl) amino)sulfonyl) phenyl)ethyl) -2-oxo-1h-pyrrole -1-carboxamide
|
WO2004066929A2
(en)
*
|
2003-01-24 |
2004-08-12 |
Bristol-Myers Squibb Company |
Cycloalkyl containing anilide ligands for the thyroid receptor
|
TW200504021A
(en)
|
2003-01-24 |
2005-02-01 |
Bristol Myers Squibb Co |
Substituted anilide ligands for the thyroid receptor
|
CZ293789B6
(cs)
*
|
2003-02-21 |
2004-07-14 |
Zentiva, A.S. |
Způsob výroby glimepiridu a příslušný meziprodukt
|
US7459474B2
(en)
*
|
2003-06-11 |
2008-12-02 |
Bristol-Myers Squibb Company |
Modulators of the glucocorticoid receptor and method
|
KR100712234B1
(ko)
*
|
2003-08-08 |
2007-04-27 |
명문제약주식회사 |
글리메피라이드의 제조방법
|
US7611693B2
(en)
|
2003-09-17 |
2009-11-03 |
Board Of Regents, The Univerisity Of Texas System |
Mechanism-based targeted pancreatic beta cell imaging and therapy
|
US7371759B2
(en)
*
|
2003-09-25 |
2008-05-13 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
NZ547752A
(en)
|
2003-11-12 |
2009-12-24 |
Phenomix Corp |
Heterocyclic boronic acid compounds for inhibiting dipeptidyl peptidase-IV
|
US7420059B2
(en)
*
|
2003-11-20 |
2008-09-02 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
US7786163B2
(en)
*
|
2004-07-12 |
2010-08-31 |
Forest Laboratories Holdings Limited (BM) |
Constrained cyano compounds
|
US7572805B2
(en)
|
2004-07-14 |
2009-08-11 |
Bristol-Myers Squibb Company |
Pyrrolo(oxo)isoquinolines as 5HT ligands
|
US7517991B2
(en)
*
|
2004-10-12 |
2009-04-14 |
Bristol-Myers Squibb Company |
N-sulfonylpiperidine cannabinoid receptor 1 antagonists
|
WO2006076598A2
(en)
*
|
2005-01-12 |
2006-07-20 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
US7368458B2
(en)
*
|
2005-01-12 |
2008-05-06 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
US7361766B2
(en)
|
2005-01-12 |
2008-04-22 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
US7317024B2
(en)
|
2005-01-13 |
2008-01-08 |
Bristol-Myers Squibb Co. |
Heterocyclic modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
WO2006078697A1
(en)
*
|
2005-01-18 |
2006-07-27 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
DE602006004964D1
(de)
*
|
2005-02-10 |
2009-03-12 |
Bristol Myers Squibb Co |
Dihydrochinazolinone als 5ht-modulatoren
|
EP1700848A1
(en)
*
|
2005-03-11 |
2006-09-13 |
IPCA Laboratories Limited |
Method for the Manufacture of Compounds Related to the Class of Substituted Sulphonyl Urea Anti-Diabetics
|
AU2005329763A1
(en)
*
|
2005-04-01 |
2006-10-05 |
Usv Limited |
A novel process for preparation of substantially pure Glimepiride
|
UA91546C2
(uk)
*
|
2005-05-03 |
2010-08-10 |
Бьорінгер Інгельхайм Інтернаціональ Гмбх |
КРИСТАЛІЧНА ФОРМА 1-ХЛОР-4-(β-D-ГЛЮКОПІРАНОЗ-1-ИЛ)-2-[4-((S)-ТЕТРАГІДРОФУРАН-3-ІЛОКСИ)-БЕНЗИЛ]-БЕНЗОЛУ, СПОСІБ ЇЇ ОДЕРЖАННЯ ТА ЇЇ ЗАСТОСУВАННЯ ПРИ ПРИГОТУВАННІ ЛІКАРСЬКИХ ЗАСОБІВ
|
US7772191B2
(en)
|
2005-05-10 |
2010-08-10 |
Boehringer Ingelheim International Gmbh |
Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein
|
US7888381B2
(en)
|
2005-06-14 |
2011-02-15 |
Bristol-Myers Squibb Company |
Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity, and use thereof
|
US7452892B2
(en)
*
|
2005-06-17 |
2008-11-18 |
Bristol-Myers Squibb Company |
Triazolopyrimidine cannabinoid receptor 1 antagonists
|
US7317012B2
(en)
*
|
2005-06-17 |
2008-01-08 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoind-1 receptor modulators
|
US20060287342A1
(en)
*
|
2005-06-17 |
2006-12-21 |
Mikkilineni Amarendra B |
Triazolopyrimidine heterocycles as cannabinoid receptor modulators
|
TW200726765A
(en)
*
|
2005-06-17 |
2007-07-16 |
Bristol Myers Squibb Co |
Triazolopyridine cannabinoid receptor 1 antagonists
|
US7632837B2
(en)
*
|
2005-06-17 |
2009-12-15 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid-1 receptor modulators
|
US7629342B2
(en)
*
|
2005-06-17 |
2009-12-08 |
Bristol-Myers Squibb Company |
Azabicyclic heterocycles as cannabinoid receptor modulators
|
JP2009502959A
(ja)
*
|
2005-07-28 |
2009-01-29 |
ブリストル−マイヤーズ スクイブ カンパニー |
セロトニン受容体アゴニストおよびアンタゴニストとしての置換テトラヒドロ−1h−ピリド[4,3,b]インドール
|
US7795436B2
(en)
*
|
2005-08-24 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted tricyclic heterocycles as serotonin receptor agonists and antagonists
|
GT200600381A
(es)
|
2005-08-25 |
2007-03-28 |
|
Compuestos organicos
|
US8618115B2
(en)
*
|
2005-10-26 |
2013-12-31 |
Bristol-Myers Squibb Company |
Substituted thieno[3,2-d]pyrimidinones as MCHR1 antagonists and methods for using them
|
US7592461B2
(en)
|
2005-12-21 |
2009-09-22 |
Bristol-Myers Squibb Company |
Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
US7553836B2
(en)
*
|
2006-02-06 |
2009-06-30 |
Bristol-Myers Squibb Company |
Melanin concentrating hormone receptor-1 antagonists
|
US20070238770A1
(en)
*
|
2006-04-05 |
2007-10-11 |
Bristol-Myers Squibb Company |
Process for preparing novel crystalline forms of peliglitazar, novel stable forms produced therein and formulations
|
PE20080697A1
(es)
|
2006-05-03 |
2008-08-05 |
Boehringer Ingelheim Int |
Derivados de benzonitrilo sustituidos con glucopiranosilo, composiciones farmaceuticas que contienen compuestos de este tipo, su uso y procedimiento para su fabricacion
|
CN101092402B
(zh)
*
|
2006-06-23 |
2012-02-08 |
唐仲雄 |
磺酰脲类化合物及其医药用途
|
US7968577B2
(en)
|
2006-11-01 |
2011-06-28 |
Bristol-Myers Squibb Company |
Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
CN101573340A
(zh)
|
2006-11-01 |
2009-11-04 |
百时美施贵宝公司 |
糖皮质激素受体AP-1和/或NF-κB活性的调节剂及其用途
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
EP2998314B1
(en)
|
2007-06-04 |
2020-01-22 |
Bausch Health Ireland Limited |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
US20090011994A1
(en)
*
|
2007-07-06 |
2009-01-08 |
Bristol-Myers Squibb Company |
Non-basic melanin concentrating hormone receptor-1 antagonists and methods
|
CL2008002427A1
(es)
|
2007-08-16 |
2009-09-11 |
Boehringer Ingelheim Int |
Composicion farmaceutica que comprende 1-cloro-4-(b-d-glucopiranos-1-il)-2-[4-((s)-tetrahidrofurano-3-iloxi)bencil]-benceno combinado con 1-[(4-metilquinazolin-2-il)metil]-3-metil-7-(2-butin-1-il)-8-(3-(r)-aminopiperidin-1-il)xantina; y su uso para tratar diabetes mellitus tipo 2.
|
US20090076125A1
(en)
*
|
2007-09-19 |
2009-03-19 |
Protia, Llc |
Deuterium-enriched glimepiride
|
WO2009058944A2
(en)
|
2007-11-01 |
2009-05-07 |
Bristol-Myers Squibb Company |
Nonsteroidal compounds useful as modulators of glucocorticoid receptor ap-1 and /or nf- kappa b activity and use thereof
|
PE20091928A1
(es)
*
|
2008-05-29 |
2009-12-31 |
Bristol Myers Squibb Co |
Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos
|
EP2328910B1
(en)
|
2008-06-04 |
2014-08-06 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
CA2730603C
(en)
|
2008-07-16 |
2019-09-24 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
KR101694136B1
(ko)
|
2009-02-13 |
2017-01-09 |
베링거 인겔하임 인터내셔날 게엠베하 |
Sglt2 억제제, dpp-iv 억제제 및 임의로 추가의 당뇨병 치료제를 포함하는 약제학적 조성물 및 이의 용도
|
CA2752435C
(en)
*
|
2009-02-13 |
2017-01-17 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition comprising glucopyranosyl diphenylmethane derivatives and pharmaceutical dosage form thereof
|
AU2010229653A1
(en)
|
2009-03-27 |
2011-10-20 |
Astrazeneca Ab |
Methods for preventing major adverse cardiovascular events with DPP-IV inhibitors
|
PL2429995T3
(pl)
|
2009-05-15 |
2014-07-31 |
Novartis Ag |
Arylopirydyny jako inhibitory syntazy aldosteronu
|
ES2430088T3
(es)
|
2009-05-15 |
2013-11-18 |
Novartis Ag |
Derivados de benzoxazolona como inhibidores de aldosterona sintasa
|
SG176009A1
(en)
|
2009-05-28 |
2011-12-29 |
Novartis Ag |
Substituted aminopropionic derivatives as neprilysin inhibitors
|
KR20120041702A
(ko)
|
2009-05-28 |
2012-05-02 |
노파르티스 아게 |
네프릴리신 억제제로서의 치환된 아미노부티르산 유도체
|
ES2546762T3
(es)
|
2009-09-30 |
2015-09-28 |
Boehringer Ingelheim International Gmbh |
Procedimientos para preparar derivados de bencil-benceno sustituidos con glucopiranosilo
|
MX2012002942A
(es)
|
2009-09-30 |
2012-04-11 |
Boehringer Ingelheim Int |
Metodo para la preparacion de una forma cristalina de 1-cloro-4-(beta-d-glucopiranos-1-il)-2-(4-((s)-teteahidrofuran-3- iloxi)bencil)-benceno.
|
UY32919A
(es)
|
2009-10-02 |
2011-04-29 |
Boehringer Ingelheim Int |
Composición farmacéutica, forma de dosificación farmacéutica, procedimiento para su preparación, mé todos para su tratamiento y sus usos
|
JP5654608B2
(ja)
|
2009-11-17 |
2015-01-14 |
ノバルティス アーゲー |
アルドステロンシンターゼ阻害剤としてのアリール−ピリジン誘導体
|
JO2967B1
(en)
|
2009-11-20 |
2016-03-15 |
نوفارتس ايه جي |
Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors
|
JP5575913B2
(ja)
|
2009-11-30 |
2014-08-20 |
ノバルティス アーゲー |
アルドステロン合成酵素阻害剤としてのイミダゾール誘導体
|
WO2012006398A2
(en)
|
2010-07-09 |
2012-01-12 |
Bhv Pharma, Inc. |
Combination immediate/delayed release delivery system for short half-life pharmaceuticals including remogliflozin
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
US8673974B2
(en)
|
2010-11-16 |
2014-03-18 |
Novartis Ag |
Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors
|
US8877815B2
(en)
|
2010-11-16 |
2014-11-04 |
Novartis Ag |
Substituted carbamoylcycloalkyl acetic acid derivatives as NEP
|
TR201101809A1
(tr)
|
2010-12-21 |
2012-07-23 |
Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ |
Vildagliptin ve glimepirid kombinasyonları.
|
AR085689A1
(es)
|
2011-03-07 |
2013-10-23 |
Boehringer Ingelheim Int |
Composiciones farmaceuticas de metformina, linagliptina y un inhibidor de sglt-2
|
IN2014CN04119A
(GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
|
2011-11-15 |
2015-07-10 |
Reddys Lab Ltd Dr |
|
US9555001B2
(en)
|
2012-03-07 |
2017-01-31 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition and uses thereof
|
US9192617B2
(en)
|
2012-03-20 |
2015-11-24 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
WO2014039411A1
(en)
|
2012-09-05 |
2014-03-13 |
Bristol-Myers Squibb Company |
Pyrrolone or pyrrolidinone melanin concentrating hormore receptor-1 antagonists
|
US9499482B2
(en)
|
2012-09-05 |
2016-11-22 |
Bristol-Myers Squibb Company |
Pyrrolone or pyrrolidinone melanin concentrating hormone receptor-1 antagonists
|
WO2014057522A1
(en)
|
2012-10-12 |
2014-04-17 |
Mochida Pharmaceutical Co., Ltd. |
Compositions and methods for treating non-alcoholic steatohepatitis
|
UY35144A
(es)
|
2012-11-20 |
2014-06-30 |
Novartis Ag |
Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca
|
KR20150119109A
(ko)
|
2013-02-14 |
2015-10-23 |
노파르티스 아게 |
Nep (중성 엔도펩티다제) 억제제로서의 치환된 비스페닐 부타노익 포스폰산 유도체
|
US10441560B2
(en)
|
2013-03-15 |
2019-10-15 |
Mochida Pharmaceutical Co., Ltd. |
Compositions and methods for treating non-alcoholic steatohepatitis
|
WO2014151206A1
(en)
|
2013-03-15 |
2014-09-25 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase and their uses
|
JP6442412B2
(ja)
|
2013-03-15 |
2018-12-19 |
持田製薬株式会社 |
非アルコール性脂肪性肝炎治療のための組成物および方法
|
EP2968439A2
(en)
|
2013-03-15 |
2016-01-20 |
Synergy Pharmaceuticals Inc. |
Compositions useful for the treatment of gastrointestinal disorders
|
TR201901110T4
(tr)
|
2013-04-05 |
2019-02-21 |
Boehringer Ingelheim Int |
Empagliflozinin terapötik kullanımları.
|
US11813275B2
(en)
|
2013-04-05 |
2023-11-14 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
HK1213818A1
(zh)
|
2013-04-05 |
2016-07-15 |
勃林格殷格翰国际有限公司 |
依帕列净的治疗用途
|
WO2014170383A1
(en)
|
2013-04-18 |
2014-10-23 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
RS65632B1
(sr)
|
2013-06-05 |
2024-07-31 |
Bausch Health Ireland Ltd |
Ultra-prečišćeni agonisti guanilat-ciklaze c, postupak njihove pripreme i upotrebe
|
CN103420891B
(zh)
*
|
2013-06-09 |
2015-10-21 |
南通市华峰化工有限责任公司 |
Ⅱ型糖尿病药物格列美脲中间体苯磺胺三光气的合成方法
|
CN103288703B
(zh)
*
|
2013-06-09 |
2015-10-21 |
南通市华峰化工有限责任公司 |
Ⅱ型糖尿病药物格列美脲中间体苯磺酰胺的合成方法
|
KR20160031552A
(ko)
|
2013-07-25 |
2016-03-22 |
노파르티스 아게 |
합성 아펠린 폴리펩티드의 생체접합체
|
US9266925B2
(en)
|
2013-07-25 |
2016-02-23 |
Novartis Ag |
Cyclic polypeptides for the treatment of heart failure
|
WO2015027021A1
(en)
|
2013-08-22 |
2015-02-26 |
Bristol-Myers Squibb Company |
Imide and acylurea derivatives as modulators of the glucocorticoid receptor
|
WO2016034710A1
(en)
|
2014-09-05 |
2016-03-10 |
Sanovel Ilac Sanayi Ve Ticaret A.S. |
Pharmaceutical combinations of sitagliptin
|
EP3009422A1
(en)
*
|
2014-10-14 |
2016-04-20 |
Ludwig-Maximilians-Universität München |
Photo-switchable sulfonylureas and their uses
|
CN107406490A
(zh)
|
2015-01-23 |
2017-11-28 |
诺华股份有限公司 |
具有改善的半衰期的合成apelin脂肪酸缀合物
|
KR20190084096A
(ko)
|
2016-11-10 |
2019-07-15 |
베링거 인겔하임 인터내셔날 게엠베하 |
약제학적 조성물, 치료 방법 및 이의 용도
|
UY38072A
(es)
|
2018-02-07 |
2019-10-01 |
Novartis Ag |
Compuestos derivados de éster butanoico sustituido con bisfenilo como inhibidores de nep, composiciones y combinaciones de los mismos
|
CN108383768A
(zh)
*
|
2018-04-13 |
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