GR72420B - - Google Patents

Info

Publication number
GR72420B
GR72420B GR59635A GR790172420A GR72420B GR 72420 B GR72420 B GR 72420B GR 59635 A GR59635 A GR 59635A GR 790172420 A GR790172420 A GR 790172420A GR 72420 B GR72420 B GR 72420B
Authority
GR
Greece
Application number
GR59635A
Other languages
Greek (el)
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of GR72420B publication Critical patent/GR72420B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
GR59635A 1978-08-11 1979-07-18 GR72420B (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93288378A 1978-08-11 1978-08-11
KR1019790002731A KR830002450B1 (ko) 1978-08-11 1979-08-10 치환 프로린의 메르캅토아실 유도체의 제조방법

Publications (1)

Publication Number Publication Date
GR72420B true GR72420B (fr) 1983-11-03

Family

ID=26626596

Family Applications (1)

Application Number Title Priority Date Filing Date
GR59635A GR72420B (fr) 1978-08-11 1979-07-18

Country Status (30)

Country Link
JP (2) JPS5527199A (fr)
KR (1) KR830002450B1 (fr)
AR (1) AR229081A1 (fr)
AT (1) AT379589B (fr)
AU (1) AU530690B2 (fr)
BE (1) BE878191A (fr)
CA (1) CA1144930A (fr)
CH (1) CH642064A5 (fr)
CS (1) CS228118B2 (fr)
DD (1) DD145749A5 (fr)
DE (1) DE2932021C2 (fr)
DK (1) DK154553C (fr)
ES (1) ES483311A1 (fr)
FI (1) FI69834C (fr)
FR (1) FR2435469A1 (fr)
GB (1) GB2028327B (fr)
GR (1) GR72420B (fr)
IE (1) IE48802B1 (fr)
IN (1) IN152712B (fr)
IT (1) IT1117782B (fr)
LU (2) LU81593A1 (fr)
NL (2) NL193374C (fr)
NZ (1) NZ191036A (fr)
PH (1) PH15030A (fr)
PT (1) PT70049A (fr)
RO (1) RO78870B (fr)
SE (1) SE447477B (fr)
SU (1) SU1066460A3 (fr)
YU (1) YU41876B (fr)
ZA (1) ZA793633B (fr)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4483861A (en) * 1978-10-31 1984-11-20 Santen Pharmaceutical Co., Ltd. Antihypertensive sulfur-containing compounds
CA1132985A (fr) * 1978-12-22 1982-10-05 John Krapcho Derives cetal et thiocetal de la mercaptoacyl proline
US4347371A (en) * 1978-12-30 1982-08-31 Santen Pharmaceutical Co., Ltd. Disulfide compounds
US4234489A (en) * 1979-06-25 1980-11-18 E. R. Squibb & Sons, Inc. Pyroglutamic acid derivatives and analogs
US4288368A (en) * 1979-07-30 1981-09-08 E. R. Squibb & Sons, Inc. Dithioacylproline derivatives
US4291040A (en) * 1979-10-22 1981-09-22 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of 4-disubstituted prolines and 4-substituted dehydroprolines
US4692458A (en) * 1980-03-05 1987-09-08 University Of Miami Anti-hypertensive agents
AU542211B2 (en) * 1980-03-07 1985-02-14 Gruppo Lepetit S.P.A. Mercaptocycloalkyl carbonyl prolines
GB2070586A (en) * 1980-03-21 1981-09-09 Squibb & Sons Inc Derivatives of Proline or Pipecolic Acid
US4284624A (en) 1980-05-02 1981-08-18 E. R. Squibb & Sons, Inc. Mixed disulfides
US4390695A (en) * 1980-06-23 1983-06-28 E. R. Squibb & Sons, Inc. Imido, amido and amino derivatives of mercaptoacyl prolines and pipecolic acids
US4578474A (en) * 1980-06-23 1986-03-25 E. R. Squibb & Sons, Inc. Imido, amido and amino derivatives of mercaptoacyl prolines and pipecolic acids
US4316905A (en) * 1980-07-01 1982-02-23 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of various 4-substituted prolines
US4332726A (en) * 1980-08-25 1982-06-01 E. R. Squibb & Sons, Inc. Purification of mercaptoacyl amino acids
US4307110A (en) * 1980-09-12 1981-12-22 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of 3-substituted proline derivatives
US4311705A (en) * 1980-10-06 1982-01-19 E. R. Squibb & Sons, Inc. Carboxyalkanoyl and hydroxycarbamoylalkanoyl derivatives of substituted prolines
US4312809A (en) 1980-10-31 1982-01-26 E. R. Squibb & Sons, Inc. Lactam derivatives of mercaptoacylamino acids
US4462943A (en) * 1980-11-24 1984-07-31 E. R. Squibb & Sons, Inc. Carboxyalkyl amino acid derivatives of various substituted prolines
US4384123A (en) * 1980-12-04 1983-05-17 E. R. Squibb & Sons, Inc. Phosphinylalkanoyl substituted prolines
US4337201A (en) * 1980-12-04 1982-06-29 E. R. Squibb & Sons, Inc. Phosphinylalkanoyl substituted prolines
US4416831A (en) 1981-04-27 1983-11-22 E. R. Squibb & Sons, Inc. Amino and substituted amino phosphinylalkanoyl compounds
US4374131A (en) 1981-04-27 1983-02-15 E. R. Squibb & Sons, Inc. Amino and substituted amino phosphinyl-alkanoyl compounds
US4381297A (en) 1981-05-04 1983-04-26 E. R. Squibb & Sons, Inc. Substituted carbonyl phosphinyl-alkanoyl compounds
US4416833A (en) 1981-05-04 1983-11-22 E. R. Squibb & Sons, Inc. Substituted carbonyl phosphinyl-alkanoyl compounds
US4497953A (en) * 1981-06-01 1985-02-05 E. R. Squibb & Sons, Inc. Imido, amido and amino derivatives of mercaptoacyl prolines and pipecolic acids
US4377701A (en) * 1981-09-21 1983-03-22 E. R. Squibb & Sons, Inc. 4-Methylene-1-[[(alranoyl or arylcarbonyl)mercapto]acyl]proline and pipecolic acid
US4555506A (en) * 1981-12-24 1985-11-26 E. R. Squibb & Sons, Inc. Phosphorus containing compounds and use as hypotensives
US4452791A (en) * 1982-03-15 1984-06-05 E. R. Squibb & Sons, Inc. Aminoalkyl and related substituted phosphinic acid angiotensin converting enzyme inhibitors
US4560680A (en) * 1982-03-15 1985-12-24 E. R. Squibb & Sons, Inc. Aminoalkyl and related substituted phosphinic acid angiotensin converting enzyme inhibitors
US4703043A (en) * 1982-06-23 1987-10-27 E. R. Squibb & Sons, Inc. Phosphonyl hydroxyacyl amino acid derivatives as antihypertensive
US4616005A (en) * 1982-06-23 1986-10-07 E. R. Squibb & Sons, Inc. Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives
US4452790A (en) * 1982-06-23 1984-06-05 E. R. Squibb & Sons, Inc. Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives
US4567166A (en) * 1982-07-14 1986-01-28 E. R. Squibb & Sons, Inc. Amino and substituted amino phosphinylalkanoyl compounds useful for treating hypertension
EP0187037A3 (fr) * 1984-12-21 1988-03-23 Takeda Chemical Industries, Ltd. Dérivés de pipéridine, leur production et emploi
CA2021409A1 (fr) * 1989-08-21 1991-02-22 Donald S. Karanewsky Amino ou imino acides a groupement phosphonate substitue, utiles comme antihypertenseurs
JPH05344844A (ja) * 1992-06-12 1993-12-27 Suzumo Kiko Kk 焼おむすびせんべいの製造方法
EP0640594A1 (fr) 1993-08-23 1995-03-01 Fujirebio Inc. Dérivé de hydantoine comme inhibiteur de métalloprotease
US5435286A (en) * 1994-05-02 1995-07-25 Cummins Engine Company, Inc. Ball link assembly for vehicle engine drive trains
GB0225379D0 (en) * 2002-10-31 2002-12-11 Pfizer Ltd Therapeutic proline derivatives
US7659305B2 (en) 2002-10-31 2010-02-09 Pfizer Inc. Therapeutic proline derivatives
WO2006038119A1 (fr) * 2004-10-08 2006-04-13 Warner-Lambert Company Llc Synthese stereoselective d'alcoxy-prolines n-protegees
GB0715626D0 (en) * 2007-08-10 2007-09-19 Generics Uk Ltd Crystalline form of zofenopril calcium
US8853421B2 (en) 2008-02-27 2014-10-07 Generics [Uk] Limited Crystalline forms of zofenopril calcium
US20110118328A1 (en) * 2008-02-27 2011-05-19 Vinayak Gore Novel crystalline forms
SI23949A (sl) 2011-12-19 2013-06-28 Silverstone Pharma Nove kristalne soli zofenoprila, postopek za njihovo dobivanje in njihova uporaba v terapiji

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2340092A2 (fr) * 1976-02-09 1977-09-02 Roussel Uclaf Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4116962A (en) * 1976-12-03 1978-09-26 E. R. Squibb & Sons, Inc. Pyrrolidine and piperidine-2-carboxylic acid derivatives
US4113715A (en) * 1977-01-17 1978-09-12 E. R. Squibb & Sons, Inc. Amino acid derivatives
US4108886A (en) * 1977-03-11 1978-08-22 E. R. Squibb & Sons, Inc. Thiopropanoylamino acid derivatives
PH15381A (en) * 1978-02-21 1982-12-17 Squibb & Sons Inc Halogen substituted mercaptoacylamino acids
US4154934A (en) * 1978-08-11 1979-05-15 E. R. Squibb & Sons, Inc. Mercaptoacylamino derivatives of heterocyclic carboxylic acids

Also Published As

Publication number Publication date
BE878191A (fr) 1980-02-11
CS228118B2 (en) 1984-05-14
NL990024I2 (nl) 1999-11-01
NL7906120A (nl) 1980-02-13
KR830001269A (ko) 1983-04-29
RO78870B (ro) 1985-01-30
IN152712B (fr) 1984-03-17
LU90403I2 (fr) 2000-07-07
FI69834C (fi) 1986-05-26
AU530690B2 (en) 1983-07-28
IE791544L (en) 1980-02-11
CA1144930A (fr) 1983-04-19
FR2435469A1 (fr) 1980-04-04
FR2435469B1 (fr) 1983-02-11
CH642064A5 (de) 1984-03-30
LU81593A1 (fr) 1979-12-07
NZ191036A (en) 1984-05-31
DK154553C (da) 1989-04-17
ES483311A1 (es) 1980-04-16
NL193374C (nl) 1999-08-03
RO78870A (fr) 1982-07-06
DD145749A5 (de) 1981-01-07
GB2028327A (en) 1980-03-05
AU4919079A (en) 1980-02-14
YU192379A (en) 1983-02-28
FI69834B (fi) 1985-12-31
ZA793633B (en) 1980-07-30
AT379589B (de) 1986-01-27
DE2932021A1 (de) 1980-02-21
DE2932021C2 (de) 1994-05-19
DK154553B (da) 1988-11-28
SE447477B (sv) 1986-11-17
PT70049A (en) 1979-09-01
NL193374B (nl) 1999-04-01
JPH01287069A (ja) 1989-11-17
JPS5527199A (en) 1980-02-27
PH15030A (en) 1982-05-13
YU41876B (en) 1988-02-29
JPH0134987B2 (fr) 1989-07-21
DK335879A (da) 1980-02-12
FI792498A (fi) 1980-02-12
SE7906722L (sv) 1980-02-12
IT7949954A0 (it) 1979-08-03
IT1117782B (it) 1986-02-24
ATA541679A (de) 1985-06-15
KR830002450B1 (ko) 1983-10-26
SU1066460A3 (ru) 1984-01-07
NL990024I1 (nl) 1999-11-01
IE48802B1 (en) 1985-05-15
AR229081A1 (es) 1983-06-15
GB2028327B (en) 1982-11-24

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