YU192379A - Process for obtaining mercaptoacyl derivatives of substituted prolines - Google Patents
Process for obtaining mercaptoacyl derivatives of substituted prolinesInfo
- Publication number
- YU192379A YU192379A YU01923/79A YU192379A YU192379A YU 192379 A YU192379 A YU 192379A YU 01923/79 A YU01923/79 A YU 01923/79A YU 192379 A YU192379 A YU 192379A YU 192379 A YU192379 A YU 192379A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- obtaining
- substituted prolines
- mercaptoacyl derivatives
- mercaptoacyl
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US93288378A | 1978-08-11 | 1978-08-11 | |
KR1019790002731A KR830002450B1 (en) | 1978-08-11 | 1979-08-10 | Method for preparing mercaptoacyl derivative of substituted proline |
Publications (2)
Publication Number | Publication Date |
---|---|
YU192379A true YU192379A (en) | 1983-02-28 |
YU41876B YU41876B (en) | 1988-02-29 |
Family
ID=26626596
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU1923/79A YU41876B (en) | 1978-08-11 | 1979-08-07 | Process for obtaining mercaptoacyl derivatives of substituted prolines |
Country Status (30)
Country | Link |
---|---|
JP (2) | JPS5527199A (en) |
KR (1) | KR830002450B1 (en) |
AR (1) | AR229081A1 (en) |
AT (1) | AT379589B (en) |
AU (1) | AU530690B2 (en) |
BE (1) | BE878191A (en) |
CA (1) | CA1144930A (en) |
CH (1) | CH642064A5 (en) |
CS (1) | CS228118B2 (en) |
DD (1) | DD145749A5 (en) |
DE (1) | DE2932021C2 (en) |
DK (1) | DK154553C (en) |
ES (1) | ES483311A1 (en) |
FI (1) | FI69834C (en) |
FR (1) | FR2435469A1 (en) |
GB (1) | GB2028327B (en) |
GR (1) | GR72420B (en) |
IE (1) | IE48802B1 (en) |
IN (1) | IN152712B (en) |
IT (1) | IT1117782B (en) |
LU (2) | LU81593A1 (en) |
NL (2) | NL193374C (en) |
NZ (1) | NZ191036A (en) |
PH (1) | PH15030A (en) |
PT (1) | PT70049A (en) |
RO (1) | RO78870B (en) |
SE (1) | SE447477B (en) |
SU (1) | SU1066460A3 (en) |
YU (1) | YU41876B (en) |
ZA (1) | ZA793633B (en) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4483861A (en) * | 1978-10-31 | 1984-11-20 | Santen Pharmaceutical Co., Ltd. | Antihypertensive sulfur-containing compounds |
CA1132985A (en) * | 1978-12-22 | 1982-10-05 | John Krapcho | Ketal and thioketal derivatives of mercaptoacyl prolines |
US4347371A (en) * | 1978-12-30 | 1982-08-31 | Santen Pharmaceutical Co., Ltd. | Disulfide compounds |
US4234489A (en) * | 1979-06-25 | 1980-11-18 | E. R. Squibb & Sons, Inc. | Pyroglutamic acid derivatives and analogs |
US4288368A (en) * | 1979-07-30 | 1981-09-08 | E. R. Squibb & Sons, Inc. | Dithioacylproline derivatives |
US4291040A (en) * | 1979-10-22 | 1981-09-22 | E. R. Squibb & Sons, Inc. | Mercaptoacyl derivatives of 4-disubstituted prolines and 4-substituted dehydroprolines |
US4692458A (en) * | 1980-03-05 | 1987-09-08 | University Of Miami | Anti-hypertensive agents |
AU542211B2 (en) * | 1980-03-07 | 1985-02-14 | Gruppo Lepetit S.P.A. | Mercaptocycloalkyl carbonyl prolines |
GB2070586A (en) * | 1980-03-21 | 1981-09-09 | Squibb & Sons Inc | Derivatives of Proline or Pipecolic Acid |
US4284624A (en) | 1980-05-02 | 1981-08-18 | E. R. Squibb & Sons, Inc. | Mixed disulfides |
US4578474A (en) * | 1980-06-23 | 1986-03-25 | E. R. Squibb & Sons, Inc. | Imido, amido and amino derivatives of mercaptoacyl prolines and pipecolic acids |
US4390695A (en) * | 1980-06-23 | 1983-06-28 | E. R. Squibb & Sons, Inc. | Imido, amido and amino derivatives of mercaptoacyl prolines and pipecolic acids |
US4316905A (en) * | 1980-07-01 | 1982-02-23 | E. R. Squibb & Sons, Inc. | Mercaptoacyl derivatives of various 4-substituted prolines |
US4332726A (en) * | 1980-08-25 | 1982-06-01 | E. R. Squibb & Sons, Inc. | Purification of mercaptoacyl amino acids |
US4307110A (en) * | 1980-09-12 | 1981-12-22 | E. R. Squibb & Sons, Inc. | Mercaptoacyl derivatives of 3-substituted proline derivatives |
US4311705A (en) * | 1980-10-06 | 1982-01-19 | E. R. Squibb & Sons, Inc. | Carboxyalkanoyl and hydroxycarbamoylalkanoyl derivatives of substituted prolines |
US4312809A (en) | 1980-10-31 | 1982-01-26 | E. R. Squibb & Sons, Inc. | Lactam derivatives of mercaptoacylamino acids |
US4462943A (en) * | 1980-11-24 | 1984-07-31 | E. R. Squibb & Sons, Inc. | Carboxyalkyl amino acid derivatives of various substituted prolines |
US4384123A (en) * | 1980-12-04 | 1983-05-17 | E. R. Squibb & Sons, Inc. | Phosphinylalkanoyl substituted prolines |
US4337201A (en) * | 1980-12-04 | 1982-06-29 | E. R. Squibb & Sons, Inc. | Phosphinylalkanoyl substituted prolines |
US4416831A (en) | 1981-04-27 | 1983-11-22 | E. R. Squibb & Sons, Inc. | Amino and substituted amino phosphinylalkanoyl compounds |
US4374131A (en) | 1981-04-27 | 1983-02-15 | E. R. Squibb & Sons, Inc. | Amino and substituted amino phosphinyl-alkanoyl compounds |
US4381297A (en) | 1981-05-04 | 1983-04-26 | E. R. Squibb & Sons, Inc. | Substituted carbonyl phosphinyl-alkanoyl compounds |
US4416833A (en) | 1981-05-04 | 1983-11-22 | E. R. Squibb & Sons, Inc. | Substituted carbonyl phosphinyl-alkanoyl compounds |
US4497953A (en) * | 1981-06-01 | 1985-02-05 | E. R. Squibb & Sons, Inc. | Imido, amido and amino derivatives of mercaptoacyl prolines and pipecolic acids |
US4377701A (en) * | 1981-09-21 | 1983-03-22 | E. R. Squibb & Sons, Inc. | 4-Methylene-1-[[(alranoyl or arylcarbonyl)mercapto]acyl]proline and pipecolic acid |
US4555506A (en) * | 1981-12-24 | 1985-11-26 | E. R. Squibb & Sons, Inc. | Phosphorus containing compounds and use as hypotensives |
US4560680A (en) * | 1982-03-15 | 1985-12-24 | E. R. Squibb & Sons, Inc. | Aminoalkyl and related substituted phosphinic acid angiotensin converting enzyme inhibitors |
US4452791A (en) * | 1982-03-15 | 1984-06-05 | E. R. Squibb & Sons, Inc. | Aminoalkyl and related substituted phosphinic acid angiotensin converting enzyme inhibitors |
US4452790A (en) * | 1982-06-23 | 1984-06-05 | E. R. Squibb & Sons, Inc. | Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives |
US4616005A (en) * | 1982-06-23 | 1986-10-07 | E. R. Squibb & Sons, Inc. | Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives |
US4703043A (en) * | 1982-06-23 | 1987-10-27 | E. R. Squibb & Sons, Inc. | Phosphonyl hydroxyacyl amino acid derivatives as antihypertensive |
US4567166A (en) * | 1982-07-14 | 1986-01-28 | E. R. Squibb & Sons, Inc. | Amino and substituted amino phosphinylalkanoyl compounds useful for treating hypertension |
EP0187037A3 (en) * | 1984-12-21 | 1988-03-23 | Takeda Chemical Industries, Ltd. | Piperidine derivatives, their production and use |
CA2021409A1 (en) * | 1989-08-21 | 1991-02-22 | Donald S. Karanewsky | Phosphonate substituted amino or imino acids useful as antihypertensives |
JPH05344844A (en) * | 1992-06-12 | 1993-12-27 | Suzumo Kiko Kk | Method for producing roasted rice ball cracker |
EP0640594A1 (en) | 1993-08-23 | 1995-03-01 | Fujirebio Inc. | Hydantoin derivative as metalloprotease inhibitor |
US5435286A (en) * | 1994-05-02 | 1995-07-25 | Cummins Engine Company, Inc. | Ball link assembly for vehicle engine drive trains |
GB0225379D0 (en) * | 2002-10-31 | 2002-12-11 | Pfizer Ltd | Therapeutic proline derivatives |
US7659305B2 (en) | 2002-10-31 | 2010-02-09 | Pfizer Inc. | Therapeutic proline derivatives |
WO2006038119A1 (en) * | 2004-10-08 | 2006-04-13 | Warner-Lambert Company Llc | Stereoselective synthesis of n-protected alkoxy prolines |
GB0715626D0 (en) | 2007-08-10 | 2007-09-19 | Generics Uk Ltd | Crystalline form of zofenopril calcium |
NZ622549A (en) * | 2008-02-27 | 2015-10-30 | Generics Uk Ltd | Novel crystalline form of zofenopril calcium |
US8853421B2 (en) | 2008-02-27 | 2014-10-07 | Generics [Uk] Limited | Crystalline forms of zofenopril calcium |
SI23949A (en) | 2011-12-19 | 2013-06-28 | Silverstone Pharma | The new crystalline salts of zofenopril, the procedure for obtaining them and their use in therapy |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2340092A2 (en) * | 1976-02-09 | 1977-09-02 | Roussel Uclaf | Analgesic (N)-thiazolyl-quinoline carboxamides - prepd. from the corresp. quinoline carboxylic acid and (2)-amino-thiazole |
AU509899B2 (en) * | 1976-02-13 | 1980-05-29 | E.R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
US4116962A (en) * | 1976-12-03 | 1978-09-26 | E. R. Squibb & Sons, Inc. | Pyrrolidine and piperidine-2-carboxylic acid derivatives |
US4113715A (en) * | 1977-01-17 | 1978-09-12 | E. R. Squibb & Sons, Inc. | Amino acid derivatives |
US4108886A (en) * | 1977-03-11 | 1978-08-22 | E. R. Squibb & Sons, Inc. | Thiopropanoylamino acid derivatives |
PH15381A (en) * | 1978-02-21 | 1982-12-17 | Squibb & Sons Inc | Halogen substituted mercaptoacylamino acids |
US4154934A (en) * | 1978-08-11 | 1979-05-15 | E. R. Squibb & Sons, Inc. | Mercaptoacylamino derivatives of heterocyclic carboxylic acids |
-
1979
- 1979-07-16 CA CA000331877A patent/CA1144930A/en not_active Expired
- 1979-07-17 NZ NZ191036A patent/NZ191036A/en unknown
- 1979-07-18 ZA ZA00793633A patent/ZA793633B/en unknown
- 1979-07-18 IN IN524/DEL/79A patent/IN152712B/en unknown
- 1979-07-18 GR GR59635A patent/GR72420B/el unknown
- 1979-07-24 AU AU49190/79A patent/AU530690B2/en not_active Expired
- 1979-07-30 FR FR7919590A patent/FR2435469A1/en active Granted
- 1979-08-01 PH PH22842A patent/PH15030A/en unknown
- 1979-08-03 IT IT49954/79A patent/IT1117782B/en active Protection Beyond IP Right Term
- 1979-08-07 YU YU1923/79A patent/YU41876B/en unknown
- 1979-08-07 DE DE2932021A patent/DE2932021C2/en not_active Expired - Lifetime
- 1979-08-08 AT AT0541679A patent/AT379589B/en not_active IP Right Cessation
- 1979-08-09 DD DD79214896A patent/DD145749A5/en not_active IP Right Cessation
- 1979-08-09 CS CS795462A patent/CS228118B2/en unknown
- 1979-08-10 SU SU792800304A patent/SU1066460A3/en active
- 1979-08-10 BE BE0/196688A patent/BE878191A/en not_active IP Right Cessation
- 1979-08-10 FI FI792498A patent/FI69834C/en not_active IP Right Cessation
- 1979-08-10 CH CH737579A patent/CH642064A5/en not_active IP Right Cessation
- 1979-08-10 DK DK335879A patent/DK154553C/en not_active IP Right Cessation
- 1979-08-10 AR AR277678A patent/AR229081A1/en active
- 1979-08-10 GB GB7927867A patent/GB2028327B/en not_active Expired
- 1979-08-10 ES ES483311A patent/ES483311A1/en not_active Expired
- 1979-08-10 IE IE1544/79A patent/IE48802B1/en active Protection Beyond IP Right Term
- 1979-08-10 LU LU81593A patent/LU81593A1/en active Protection Beyond IP Right Term
- 1979-08-10 PT PT70049A patent/PT70049A/en unknown
- 1979-08-10 RO RO98428A patent/RO78870B/en unknown
- 1979-08-10 NL NL7906120A patent/NL193374C/en active Protection Beyond IP Right Term
- 1979-08-10 KR KR1019790002731A patent/KR830002450B1/en active
- 1979-08-10 SE SE7906722A patent/SE447477B/en active Protection Beyond IP Right Term
- 1979-08-10 JP JP10272279A patent/JPS5527199A/en active Granted
-
1988
- 1988-12-21 JP JP63323204A patent/JPH01287069A/en active Pending
-
1999
- 1999-06-04 LU LU90403C patent/LU90403I2/en unknown
- 1999-08-04 NL NL990024C patent/NL990024I1/en unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
YU192379A (en) | Process for obtaining mercaptoacyl derivatives of substituted prolines | |
YU42655B (en) | Process for obtaining derivatives of carboxialkyldipeptides | |
YU41278B (en) | Process for obtaining new derivatives of 4-amino-5-alkyl-sulfonyl-orthoanisamide | |
YU80379A (en) | Process for obtaining thioethianic acid derivatives | |
YU67183A (en) | Process for obtaining new derivatives of 6-beta-hydroxyalkyl penicillinates | |
HU186344B (en) | Process for prodiction of solid cianur-chlorid | |
GB2039478B (en) | Mercaptoacyl derivatives of pyrrolidines or piperidenes | |
EG13932A (en) | Process for preparing of cis-hexahydrodibenzo pyranones | |
YU40845B (en) | Process for obtaining methane sulfanates of imidazole derivatives | |
YU84179A (en) | Process for obtaining 2-aminopyridone derivatives | |
YU136880A (en) | Process for obtaining new derivatives of 3-vinyl-cephalosporin | |
YU80179A (en) | Process for obtaining lysergol derivatives | |
GB2122605B (en) | Mercaptoacyl derivatives of prolines | |
YU42653B (en) | Process for obtaining n-benzylhaloacetamide derivatives | |
YU228479A (en) | Process for producing substituted furanes | |
YU187879A (en) | Process for obtaining derivatives of phenyliminomethyl pyridine | |
HU178397B (en) | Process for preparing substituted derivatives of steroid-spiro-oxazolidione derivatives | |
YU43123B (en) | Process for obtaining substituted derivatives of acylcarbamides | |
AU4618479A (en) | Process of substituted norbornene derivatives | |
GB2040937B (en) | Derivatives of mercaptoacyl hydroxy prolines | |
IL57967A0 (en) | Mercaptoacyl derivatives of substituted prolines | |
GB2027700B (en) | Process for the preparation of tricyclazole | |
YU40848B (en) | Process for obtaining benzoxazolyl - propionic acid derivatives | |
IL58375A0 (en) | Process for making new derivatives of dimers of isoeugenol | |
GB2032922B (en) | Process for the production of 2-chloro-benzonitrile derivatives |