GR3035372T3 - Tachykinin antagonists. - Google Patents
Tachykinin antagonists.Info
- Publication number
- GR3035372T3 GR3035372T3 GR20010400199T GR20010400199T GR3035372T3 GR 3035372 T3 GR3035372 T3 GR 3035372T3 GR 20010400199 T GR20010400199 T GR 20010400199T GR 20010400199 T GR20010400199 T GR 20010400199T GR 3035372 T3 GR3035372 T3 GR 3035372T3
- Authority
- GR
- Greece
- Prior art keywords
- compounds
- tachykinin antagonists
- nonpeptides
- tachykinins
- allergies
- Prior art date
Links
- 102000003141 Tachykinin Human genes 0.000 title abstract 3
- 108060008037 tachykinin Proteins 0.000 title abstract 3
- 239000005557 antagonist Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 208000035475 disorder Diseases 0.000 abstract 2
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 230000036407 pain Effects 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 230000002792 vascular Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US93025292A | 1992-08-13 | 1992-08-13 | |
US9726493A | 1993-07-23 | 1993-07-23 | |
PCT/US1993/007552 WO1994004494A1 (en) | 1992-08-13 | 1993-08-12 | Tachykinin antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
GR3035372T3 true GR3035372T3 (en) | 2001-05-31 |
Family
ID=26793050
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR20010400199T GR3035372T3 (en) | 1992-08-13 | 2001-02-06 | Tachykinin antagonists. |
Country Status (13)
Country | Link |
---|---|
US (4) | US5594022A (el) |
EP (2) | EP1000930A3 (el) |
JP (1) | JP3507494B2 (el) |
AT (1) | ATE197793T1 (el) |
AU (1) | AU687754B2 (el) |
CA (1) | CA2140640A1 (el) |
DE (1) | DE69329712T2 (el) |
DK (1) | DK0655055T3 (el) |
ES (1) | ES2153841T3 (el) |
GR (1) | GR3035372T3 (el) |
NZ (1) | NZ255721A (el) |
PT (1) | PT655055E (el) |
WO (1) | WO1994004494A1 (el) |
Families Citing this family (87)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0659409A3 (en) * | 1993-11-23 | 1995-08-09 | Pfizer | Substance P antagonists for the inhibition of angiogenesis. |
IL113472A0 (en) | 1994-04-29 | 1995-07-31 | Lilly Co Eli | Non-peptidyl tachykinin receptor antogonists |
JPH10501228A (ja) * | 1994-06-06 | 1998-02-03 | ワーナー−ランバート・コンパニー | タキキニン(nk▲下1▼)受容体アンタゴニスト |
US5597845A (en) * | 1994-06-20 | 1997-01-28 | Merrell Pharmaceuticals Inc. | Substituted alkyldiamine derivatives |
PL180866B1 (pl) | 1994-07-12 | 2001-04-30 | Lilly Co Eli | Nowy trihydrat dichlorowodorku (R)-3-(1H-indol-3-ilo)-1-[N-(2-metoksybenzylo)acetyloamino]-2-[N-(2-(4-(piperydyn-1-ylo)piperydyn-1-ylo)acetylo)amino]propanu |
US5554641A (en) * | 1995-03-20 | 1996-09-10 | Horwell; David C. | Nonpeptides as tachykinin antagonists |
AU5966196A (en) * | 1995-06-08 | 1997-01-09 | Eli Lilly And Company | Methods of treating cold and allergic rhinitis |
AU5966096A (en) * | 1995-06-09 | 1997-01-09 | Eli Lilly And Company | Methods of treating cold and allergic rhinitis |
NZ333062A (en) * | 1996-06-26 | 2000-06-23 | Warner Lambert Co | Use of [R,S]-[2-(1H-indol-3-yl)-1-methyl-1-(1-phenyl-ethylcarbamoyl)-ethyl]-carbamic acid benzofuran-2yl methyl ester in the treatment of emesis |
NZ333038A (en) * | 1996-08-22 | 2000-10-27 | Warner Lambert Co | Non-peptide bombesin receptor antagonists |
ATE258050T1 (de) * | 1996-10-31 | 2004-02-15 | Harbor Branch Oceanographic | Verwendung neurogen-entzuendungshemmender verbindungen und zusammensetzungen |
US6339094B1 (en) * | 1997-08-06 | 2002-01-15 | Eli Lilly And Company | 2-acylaminopropanamines as tachykinin receptor antagonists |
BR9811821A (pt) * | 1997-08-06 | 2000-08-15 | Lilly Co Eli | 2-acilaminopropanaminas como antagonistas de receptores de taquicinina |
WO1999042092A2 (en) * | 1998-02-20 | 1999-08-26 | Harbor Branch Oceanographic Institution, Inc. | Compounds and methods of use for treatment of neurogenic inflammation |
EP1075472A1 (en) * | 1998-04-15 | 2001-02-14 | Warner-Lambert Company | Prodrugs of benzofuranylmethyl carbamate nk 1? antagonists |
AU746963B2 (en) | 1998-06-12 | 2002-05-09 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Imidazolyl derivatives |
WO2000037462A1 (en) * | 1998-12-18 | 2000-06-29 | Warner-Lambert Company | Non-peptide nk1 receptors antagonists |
US6455734B1 (en) * | 2000-08-09 | 2002-09-24 | Magnesium Diagnostics, Inc. | Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states |
US6372440B2 (en) | 1999-03-10 | 2002-04-16 | Magnesium Diagnostics, Inc. | Method for detecting deficient cellular membrane tightly bound magnesium for disease diagnoses |
WO2000056760A1 (en) * | 1999-03-23 | 2000-09-28 | The United States Of America, Represented By Secretary, Department Of Health And Human Services | Phenylalanine derivatives |
US7226991B1 (en) * | 1999-03-23 | 2007-06-05 | United States Of America, Represented By The Secretary, Department Of Health And Human Services | Phenylalanine derivatives |
DE19922316A1 (de) * | 1999-05-14 | 2000-11-16 | Goedecke Ag | Verfahren zur Herstellung von (R)-N-[(Benzo[b]furan-2-yl)-alkoxycarbonyl]-tryptophanalkylestern |
DE19922317A1 (de) * | 1999-05-14 | 2000-11-16 | Goedecke Ag | Verfahren zur Herstellung von (R)-N-[(Benzo[b]furan-2-yl)-alkoxycarbonyl]- tryptophanalkylestern |
DE19922315A1 (de) * | 1999-05-14 | 2000-11-16 | Goedecke Ag | Verfahren zur Herstellung von (R)-N-[(Benzo[b] furan-2-yl)-alkoxycarbonyl]- tryptophanalkylestern |
IT1306165B1 (it) * | 1999-07-05 | 2001-05-30 | Innova Ltd | Impiego di inibitori della sostanza p per il trattamento degliadenocarcinomi. |
GB9927125D0 (en) | 1999-11-16 | 2000-01-12 | Univ Reading The | Placental human neurokinin B precursor |
IL150203A0 (en) * | 1999-12-22 | 2002-12-01 | Warner Lambert Co | Non peptide tachykinin receptor antagonists |
AUPQ514600A0 (en) * | 2000-01-18 | 2000-02-10 | James Cook University | Brain injury treatment |
AU5216801A (en) * | 2000-03-16 | 2001-09-24 | Hoffmann La Roche | Carboxylic acid derivatives as ip antagonists |
ATE367811T1 (de) * | 2000-06-12 | 2007-08-15 | Univ Rochester | Methode zur behandlung von hitzewallungen, durch verwendung eines tachikinin-rezeptor antagonisten |
JP2004518613A (ja) | 2000-08-01 | 2004-06-24 | ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス | イミダゾリル誘導体 |
GB2369117A (en) * | 2000-11-17 | 2002-05-22 | Warner Lambert Co | Bombesin receptor antagonists |
US6337069B1 (en) * | 2001-02-28 | 2002-01-08 | B.M.R.A. Corporation B.V. | Method of treating rhinitis or sinusitis by intranasally administering a peptidase |
US6709651B2 (en) | 2001-07-03 | 2004-03-23 | B.M.R.A. Corporation B.V. | Treatment of substance P-related disorders |
MY130373A (en) | 2001-10-29 | 2007-06-29 | Malesci Sas | Linear basic compounds having nk-2 antagonist activity and formulations thereof |
GB0215392D0 (en) * | 2002-07-03 | 2002-08-14 | Glaxo Group Ltd | Chemical compounds |
FR2847471B1 (fr) * | 2002-11-25 | 2006-12-29 | Expanscience Lab | Composition comprenant au moins un derive d'acide carbamique ,son utilisation cosmetique et comme medicament |
EP1615885A1 (en) * | 2003-04-15 | 2006-01-18 | Warner-Lambert Company LLC | B -fused bicyclic proline derivatives and their use for treating arthritic conditions |
US7456164B2 (en) * | 2004-05-07 | 2008-11-25 | Pfizer, Inc | 3- or 4-monosubtituted phenol and thiophenol derivatives useful as H3 ligands |
KR101412339B1 (ko) | 2004-07-15 | 2014-06-25 | 알바니 몰레큘라 리써치, 인크. | 아릴- 및 헤테로아릴-치환된 테트라히드로이소퀴놀린, 및이것의 노르에피네프린, 도파민 및 세로토닌의 재흡수를차단하기 위한 용도 |
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-
1993
- 1993-08-12 NZ NZ255721A patent/NZ255721A/en unknown
- 1993-08-12 DE DE69329712T patent/DE69329712T2/de not_active Expired - Fee Related
- 1993-08-12 EP EP00102502A patent/EP1000930A3/en not_active Withdrawn
- 1993-08-12 EP EP93919974A patent/EP0655055B1/en not_active Expired - Lifetime
- 1993-08-12 PT PT93919974T patent/PT655055E/pt unknown
- 1993-08-12 AU AU50055/93A patent/AU687754B2/en not_active Ceased
- 1993-08-12 CA CA002140640A patent/CA2140640A1/en not_active Abandoned
- 1993-08-12 WO PCT/US1993/007552 patent/WO1994004494A1/en active IP Right Grant
- 1993-08-12 ES ES93919974T patent/ES2153841T3/es not_active Expired - Lifetime
- 1993-08-12 AT AT93919974T patent/ATE197793T1/de not_active IP Right Cessation
- 1993-08-12 JP JP50638394A patent/JP3507494B2/ja not_active Expired - Fee Related
- 1993-08-12 DK DK93919974T patent/DK0655055T3/da active
-
1994
- 1994-11-29 US US08/344,064 patent/US5594022A/en not_active Expired - Fee Related
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1996
- 1996-10-08 US US08/727,067 patent/US5716979A/en not_active Expired - Fee Related
-
1997
- 1997-10-17 US US08/953,037 patent/US5856354A/en not_active Expired - Fee Related
-
1998
- 1998-10-08 US US09/168,512 patent/US5981755A/en not_active Expired - Fee Related
-
2001
- 2001-02-06 GR GR20010400199T patent/GR3035372T3/el not_active IP Right Cessation
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EP0655055A1 (en) | 1995-05-31 |
AU687754B2 (en) | 1998-03-05 |
JPH08500361A (ja) | 1996-01-16 |
US5856354A (en) | 1999-01-05 |
JP3507494B2 (ja) | 2004-03-15 |
US5981755A (en) | 1999-11-09 |
AU5005593A (en) | 1994-03-15 |
NZ255721A (en) | 1997-06-24 |
DE69329712D1 (de) | 2001-01-04 |
EP1000930A2 (en) | 2000-05-17 |
DE69329712T2 (de) | 2001-04-12 |
EP0655055B1 (en) | 2000-11-29 |
US5594022A (en) | 1997-01-14 |
ES2153841T3 (es) | 2001-03-16 |
US5716979A (en) | 1998-02-10 |
DK0655055T3 (da) | 2001-01-02 |
ATE197793T1 (de) | 2000-12-15 |
WO1994004494A1 (en) | 1994-03-03 |
EP1000930A3 (en) | 2003-10-29 |
CA2140640A1 (en) | 1994-03-03 |
PT655055E (pt) | 2001-03-30 |
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