GR3029352T3 - Luciferase compositions and methods - Google Patents

Luciferase compositions and methods

Info

Publication number
GR3029352T3
GR3029352T3 GR990400439T GR990400439T GR3029352T3 GR 3029352 T3 GR3029352 T3 GR 3029352T3 GR 990400439 T GR990400439 T GR 990400439T GR 990400439 T GR990400439 T GR 990400439T GR 3029352 T3 GR3029352 T3 GR 3029352T3
Authority
GR
Greece
Prior art keywords
luciferase
methods
luciferin
coenzyme
compositions
Prior art date
Application number
GR990400439T
Other languages
English (en)
Inventor
Keith V Wood
Original Assignee
Promega Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24320802&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR3029352(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Promega Corp filed Critical Promega Corp
Publication of GR3029352T3 publication Critical patent/GR3029352T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y113/00—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
    • C12Y113/12—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)(1.13.12)
    • C12Y113/12007—Photinus-luciferin 4-monooxygenase (ATP-hydrolysing) (1.13.12.7), i.e. firefly-luciferase
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit
GR990400439T 1990-09-10 1999-02-10 Luciferase compositions and methods GR3029352T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/580,371 US5283179A (en) 1990-09-10 1990-09-10 Luciferase assay method
PCT/US1991/006474 WO1992004468A1 (en) 1990-09-10 1991-09-09 Luciferase compositions and methods

Publications (1)

Publication Number Publication Date
GR3029352T3 true GR3029352T3 (en) 1999-05-28

Family

ID=24320802

Family Applications (1)

Application Number Title Priority Date Filing Date
GR990400439T GR3029352T3 (en) 1990-09-10 1999-02-10 Luciferase compositions and methods

Country Status (10)

Country Link
US (4) US5283179A (el)
EP (1) EP0553234B2 (el)
JP (2) JP3171595B2 (el)
AT (1) ATE173298T1 (el)
AU (1) AU649289B2 (el)
DE (1) DE69130482T3 (el)
DK (1) DK0553234T4 (el)
ES (1) ES2126576T5 (el)
GR (1) GR3029352T3 (el)
WO (1) WO1992004468A1 (el)

Families Citing this family (108)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283179A (en) * 1990-09-10 1994-02-01 Promega Corporation Luciferase assay method
GB9224058D0 (en) * 1992-11-17 1993-01-06 Celsis Ltd Bioluminescence reagent formulation
AT401526B (de) * 1993-02-10 1996-09-25 Scheirer Winfried Reagenzlösung zur stabilisierung der lumineszenz bei der luciferasemessung
JP2651651B2 (ja) * 1993-04-21 1997-09-10 チッソ株式会社 蛍酵素ルシフェラーゼ遺伝子
US5695928A (en) 1993-12-10 1997-12-09 Novartis Corporation Rapid immunoassay for detection of antibodies or antigens incorporating simultaneous sample extraction and immunogenic reaction
US6770446B1 (en) * 1994-06-14 2004-08-03 Wyeth Cell systems having specific interaction of peptide binding pairs
US7255851B2 (en) * 1994-07-01 2007-08-14 The Board Of Trustees Of The Leland Stanford Junior University Non-invasive localization of a light-emitting conjugate in a mammal
US6217847B1 (en) 1994-07-01 2001-04-17 The Board Of Trustees Of The Leland Stanford Junior University Non-invasive localization of a light-emitting conjugate in a mammal
US5679515A (en) * 1994-10-03 1997-10-21 Pathogenesis Corporation Mycobacterial reporter strains and uses thereof
US5744320A (en) * 1995-06-07 1998-04-28 Promega Corporation Quenching reagents and assays for enzyme-mediated luminescence
WO1997008342A1 (en) * 1995-08-30 1997-03-06 Gentest Corporation Cytochrome p450 reporter gene
US8349602B1 (en) 1996-04-19 2013-01-08 Xenogen Corporation Biodetectors targeted to specific ligands
US5798263A (en) * 1996-09-05 1998-08-25 Promega Corporation Apparatus for quantifying dual-luminescent reporter assays
US6602677B1 (en) * 1997-09-19 2003-08-05 Promega Corporation Thermostable luciferases and methods of production
US6171809B1 (en) * 1998-01-29 2001-01-09 Packard Instrument Company Method and compositions for detecting luciferase biological samples
CA2263784A1 (en) 1998-03-23 1999-09-23 Megabios Corporation Dual-tagged proteins and their uses
US6183978B1 (en) * 1998-09-04 2001-02-06 Tropix, Inc. Luciferase assay, compositions and kits for use in connection therewith
NL1010224C2 (nl) * 1998-09-30 2000-03-31 Packard Biosciene B V Werkwijze voor het detecteren van ATP.
WO2000040746A1 (en) * 1999-01-08 2000-07-13 Medical Analysis Systems, Inc. Compositions and methods for stabilizing thiol-containing biomolecules
US6410255B1 (en) 1999-05-05 2002-06-25 Aurora Biosciences Corporation Optical probes and assays
JP2001103972A (ja) 1999-10-06 2001-04-17 Kikkoman Corp ルシフェリンを再生する能力を有するタンパク質をコードする遺伝子、新規な組み換え体ｄｎａ及びルシフェリンを再生する能力を有するタンパク質の製造法
US20040214227A1 (en) * 1999-12-22 2004-10-28 Erik Joly Bioluminescence resonance energy transfer (bret) fusion molecule and method of use
US6502774B1 (en) * 2000-03-08 2003-01-07 J + L Fiber Services, Inc. Refiner disk sensor and sensor refiner disk
US6927851B2 (en) * 2000-03-31 2005-08-09 Neogen Corporation Methods and apparatus to improve the sensitivity and reproducibility of bioluminescent analytical methods
US6667287B2 (en) * 2000-04-20 2003-12-23 Colgate-Palmolive Company Light duty cleaning composition comprising an amine oxide and polyacrylic acid homopolymer
JP2004527204A (ja) * 2000-04-24 2004-09-09 ワイエス ペプチド結合対の特異的相互作用を有する新規な細胞系
WO2001093930A1 (en) * 2000-06-02 2001-12-13 The University Of Utah Research Foundation Active needle devices with integrated functionality
US7118878B1 (en) 2000-06-09 2006-10-10 Promega Corporation Method for increasing luminescence assay sensitivity
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
US20030157643A1 (en) * 2000-08-24 2003-08-21 Almond Brian D Synthetic nucleic acids from aquatic species
US7879540B1 (en) * 2000-08-24 2011-02-01 Promega Corporation Synthetic nucleic acid molecule compositions and methods of preparation
US6596506B2 (en) 2000-10-27 2003-07-22 President And Fellows Of Harvard College Double and triple readout assay systems
US6660489B2 (en) 2000-12-01 2003-12-09 Becton, Dickinson And Company ATP extraction method
CA2328684A1 (en) * 2000-12-15 2002-06-15 Yahia Gawad Photon-triggered luminescent assay
JP4880188B2 (ja) * 2001-01-23 2012-02-22 プレジデント アンド フェロウズ オブ ハーバード カレッジ 核酸プログラム型タンパク質アレイ
US7666615B2 (en) * 2001-01-29 2010-02-23 Hemogenix, Inc. High-throughput assay of hematopoietic stem and progenitor cell proliferation
US7354730B2 (en) * 2002-01-29 2008-04-08 Hemogenix, Inc. High-throughput assay of hematopoietic stem and progenitor cell proliferation
US7989178B2 (en) * 2001-01-29 2011-08-02 Hemogenix, Inc. Colony assay miniaturization with enumeration output
AU2002335610C1 (en) * 2001-01-29 2008-09-25 Hemogenix, Inc. High-throughput stem cell assay of hematopoietic stem and progenitor cell proliferation
US7083911B2 (en) * 2001-02-16 2006-08-01 Promega Corporation Method for detection of ATP
US6858773B2 (en) * 2001-04-20 2005-02-22 Xenogen Corporation Transgenic mice comprising transcription control elements associated with mouse eosinophil peroxidase expression
US20030135871A1 (en) * 2001-08-15 2003-07-17 Nawotka Kevin A. Modified railroad worm red luciferase coding sequences
US7268229B2 (en) * 2001-11-02 2007-09-11 Promega Corporation Compounds to co-localize luminophores with luminescent proteins
AU2002348287A1 (en) * 2001-11-16 2003-06-10 Pierce Biotechnology, Inc. Phosphine-containing formulations for chemiluminescent luciferase assays
US7482366B2 (en) 2001-12-21 2009-01-27 X-Ceptor Therapeutics, Inc. Modulators of LXR
CA2469435A1 (en) 2001-12-21 2003-07-24 X-Ceptor Therapeutics, Inc. Modulators of lxr
ATE521599T1 (de) * 2001-12-21 2011-09-15 X Ceptor Therapeutics Inc Heterocyclische modulatoren von nukleären rezeptoren
US20040044063A1 (en) * 2002-05-31 2004-03-04 Brent Stockwell SMA therapy and cell based assay for identifying therapies
EP1539997A4 (en) * 2002-08-21 2007-04-25 Ivan N Rich HIGH-PERFORMANCE PROLIFERATION ASSAY OF HEMATOPOIETIC STRAINS AND PROGENITOR CELLS
JP2004089117A (ja) * 2002-09-03 2004-03-25 Toyo B-Net Co Ltd ルシフェラーゼ検出試薬キット及び当該キットを使用したルシフェラーゼ検出方法
EP1546374B1 (en) 2002-09-06 2010-11-10 Promega Corporation Method for detecting transferase enzymatic activity
WO2004027378A2 (en) * 2002-09-20 2004-04-01 Promega Corporation Luminescence-based methods and probes for measuring cytochrome p450 activity
US7413874B2 (en) * 2002-12-09 2008-08-19 University Of Miami Nucleic acid encoding fluorescent proteins from aquatic species
EP2325329B1 (en) 2002-12-23 2014-02-12 Promega Corporation Improved luciferase-based assays
US20080227085A1 (en) * 2003-01-17 2008-09-18 Pellegrini Matthew C Methods and Systems for the Identification of Rna Regulatory Sequences and Compounds that Modulate their Function
JP2006517413A (ja) * 2003-02-12 2006-07-27 プロメガ　コーポレイション 光を発光反応から消失させる二重酵素アッセイの方法及びキット
US7390670B2 (en) 2003-02-20 2008-06-24 Lumigen, Inc. Signalling compounds and methods for detecting hydrogen peroxide
US6970240B2 (en) * 2003-03-10 2005-11-29 Applera Corporation Combination reader
DE10315640A1 (de) * 2003-04-04 2004-10-14 Ignatov, Konstantin Verfahren zur kontrollierten Freisetzung von Komponenten in eine Lösung
US7494781B1 (en) 2003-05-12 2009-02-24 Charm Sciences, Inc. Sensitive method for detecting low levels of ATP
US7132249B1 (en) 2003-05-12 2006-11-07 Charm Sciences, Inc. Method of determining allergenic food on surfaces
CA2445420A1 (en) 2003-07-29 2005-01-29 Invitrogen Corporation Kinase and phosphatase assays
US7727752B2 (en) * 2003-07-29 2010-06-01 Life Technologies Corporation Kinase and phosphatase assays
WO2005014796A2 (en) 2003-08-08 2005-02-17 Invitrogen Corporation Methods and compositions for seamless cloning of nucleic acid molecules
WO2005035719A2 (en) * 2003-10-03 2005-04-21 Board Of Control Of Michigan Technological University Modified luciferase
ATE469984T1 (de) 2003-12-01 2010-06-15 Life Technologies Corp Rekombinationsstellen enthaltende nukleinsäuremoleküle und verfahren zur verwendung davon
ATE429507T1 (de) * 2004-07-02 2009-05-15 Promega Corp Zusammensetzungen und verfahren zur extraktion und detektion von mikrobiellem atp
US7728118B2 (en) 2004-09-17 2010-06-01 Promega Corporation Synthetic nucleic acid molecule compositions and methods of preparation
TWI290956B (en) * 2004-12-31 2007-12-11 Ind Tech Res Inst Luminescence-based recipe and device using the same
US7939286B2 (en) * 2005-03-07 2011-05-10 Targeting Systems Enhancing a luminescent signal
US20060214141A1 (en) * 2005-03-23 2006-09-28 Yankielun Norbert E Luminescent illumination adjunct for night vision
US20060234323A1 (en) * 2005-04-18 2006-10-19 Cali James J Luminescent ATP detection with extended linearity
EP1724359A1 (en) 2005-05-18 2006-11-22 PerkinElmer Life and Analytical Sciences B.V. Luciferase assay system
EP2778234B1 (en) * 2005-05-31 2017-09-27 Promega Corporation Luminogenic and fluorogenic compounds and methods to detect molecules or conditions
CA2613522A1 (en) 2005-06-27 2007-01-04 Exelixis, Inc. Imidazole based lxr modulators
CN101501187A (zh) * 2006-06-06 2009-08-05 田纳西大学研究基金会 富含赘生干细胞的组合物及包含其的方法
US8178316B2 (en) * 2006-06-29 2012-05-15 President And Fellows Of Harvard College Evaluating proteins
US20100129840A1 (en) * 2006-10-13 2010-05-27 Charm Scineces, Inc Method and Apparatus for Reducing Luminescent Test Result Interferences
JP2008113620A (ja) * 2006-11-07 2008-05-22 Toyobo Co Ltd ルシフェラーゼの発光方法
DE102006054562A1 (de) * 2006-11-20 2008-05-21 Bayer Healthcare Ag Verfahren zum Nachweis von Pyrophosphat mit Biolumineszenz Detektion
CN101636504B (zh) 2006-12-21 2012-10-31 基因流股份有限公司 利用分泌性荧光素酶的生物发光测定
US8603950B2 (en) 2007-02-20 2013-12-10 Anaptysbio, Inc. Methods of generating libraries and uses thereof
WO2008109459A1 (en) 2007-03-02 2008-09-12 University Of Massachusetts Luciferins
WO2008118445A1 (en) * 2007-03-26 2008-10-02 Promega Corporation Methods to quench light from optical reactions
US20090081715A1 (en) * 2007-09-07 2009-03-26 Cobalt Technologies, Inc., A Delaware Corporation Engineered Light-Emitting Reporter Genes
JP5332178B2 (ja) * 2007-11-02 2013-11-06 東洋紡株式会社 多色ルシフェラーゼの検出方法
WO2009061837A1 (en) * 2007-11-05 2009-05-14 Novostem Therapeutics Inc Neoplastic stem cell system and method
GB2459756B (en) 2008-04-09 2012-04-04 Cobalt Technologies Inc Enhanced ABE fermentation with high yielding butanol tolerant Clostridium strains
WO2010021686A1 (en) * 2008-08-18 2010-02-25 Promega Corporation Luminogenic compounds and methods to detect cytochrome p450 3a enzymes
WO2010113039A1 (en) 2009-04-03 2010-10-07 Medical Research Council Mutants of activation-induced cytidine deaminase (aid) and methods of use
AU2010266035B2 (en) * 2009-06-26 2015-02-12 Talfryn S.A. Integrated system and process for bioproduct production
US8569002B2 (en) 2010-10-20 2013-10-29 The Board Of Regents Of The University Of Texas System Multiplexed luciferase reporter assay systems
JP5863338B2 (ja) 2011-08-25 2016-02-16 株式会社東芝 プラスミド型ベクター、遺伝子プロモーター活性の検出方法、及びアッセイキット
WO2013037482A1 (en) 2011-09-15 2013-03-21 Phenex Pharmaceuticals Ag Farnesoid x receptor agonists for cancer treatment and prevention
US9074186B2 (en) 2012-08-15 2015-07-07 Boston Medical Center Corporation Production of red blood cells and platelets from stem cells
WO2015116867A1 (en) 2014-01-29 2015-08-06 Promega Corporation Quinone-masked probes as labeling reagents for cell uptake measurements
EP3313846B1 (en) * 2015-06-25 2020-05-06 Promega Corporation Thienopyrrole compounds and uses thereof as inhibitors of oplophorus-derived luciferases
CN108026172B (zh) 2015-06-26 2022-04-29 赛诺菲生物技术公司 单克隆抗il-1racp抗体
JP6441534B2 (ja) 2016-03-11 2018-12-19 国立研究開発法人産業技術総合研究所 発光酵素タンパク質
EP3241845A1 (en) 2016-05-06 2017-11-08 MAB Discovery GmbH Humanized anti-il-1r3 antibodies
WO2018125992A1 (en) 2016-12-28 2018-07-05 Promega Corporation Functionalized nanoluc inhibitors
EP3401332A1 (en) 2017-05-08 2018-11-14 MAB Discovery GmbH Anti-il-1r3 antibodies for use in inflammatory conditions
CN111089859A (zh) * 2018-10-23 2020-05-01 北京中医药大学 新型三磷酸腺苷生物发光测定方法及其用途
RU2744869C2 (ru) * 2019-08-08 2021-03-16 Общество с ограниченной ответственностью "ПЛАНТА" Метод и реактивы для детекции активности люциферазы
CN113030052B (zh) * 2021-03-18 2022-10-21 中国科学院华南植物园 一种香蕉采后果实eATP水平的检测方法
CA3217862A1 (en) 2021-05-05 2022-11-10 Radius Pharmaceuticals, Inc. Animal model having homologous recombination of mouse pth1 receptor
CN114350626A (zh) * 2021-12-21 2022-04-15 合肥巅峰生物科技有限公司 一种荧光素酶冻干粉稀释反应液
CN114736949B (zh) * 2022-03-22 2024-03-01 药科元(上海)生物技术有限公司 一种萤火虫荧光素酶报告基因检测试剂盒

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE428379B (sv) * 1978-05-31 1983-06-27 Lkb Produkter Ab Bioluminiscens bestemning av atp och reagens herfor
DE2828658C3 (de) * 1978-06-29 1981-10-22 Lkb-Produkter Ab, Stockholm Verfahren zur photometrischen Bestimmung der Untereinheit B der Creatinkinase und Reagens hierfür
US4234681A (en) * 1978-07-21 1980-11-18 The Regents Of The University Of California Immobolized light emitting systems
US4614712A (en) * 1983-02-25 1986-09-30 The Upjohn Company Immunoassays with luciferase labeled ligands or receptors
US4665022A (en) * 1984-02-17 1987-05-12 The Regents Of The University Of California Bioluminescent assay reagent and method
FR2566798B1 (fr) * 1984-06-27 1986-12-12 Centre Nat Rech Scient Membrane porteuse de la luciferase pour le dosage de l'atp et son procede de production
JPS6163855A (ja) * 1984-09-05 1986-04-02 Fuji Photo Film Co Ltd 静電写真用液体現像剤
DK258787D0 (da) * 1987-05-21 1987-05-21 Foss Electric As N Fremgangsmaade til bestemmelse af bakteriekoncentration i en proeve
GB8722252D0 (en) * 1987-09-22 1987-10-28 Brewing Res Found Atp extraction
US5283179A (en) * 1990-09-10 1994-02-01 Promega Corporation Luciferase assay method

Also Published As

Publication number Publication date
ES2126576T3 (es) 1999-04-01
US5641641A (en) 1997-06-24
US5650289A (en) 1997-07-22
DK0553234T3 (da) 1999-07-26
JP2001224398A (ja) 2001-08-21
EP0553234A1 (en) 1993-08-04
EP0553234B1 (en) 1998-11-11
JP3171595B2 (ja) 2001-05-28
WO1992004468A1 (en) 1992-03-19
AU649289B2 (en) 1994-05-19
EP0553234B2 (en) 2005-07-13
JPH06500921A (ja) 1994-01-27
DK0553234T4 (da) 2005-08-01
US5283179A (en) 1994-02-01
AU8858391A (en) 1992-03-30
DE69130482T3 (de) 2006-05-04
ATE173298T1 (de) 1998-11-15
US5814471A (en) 1998-09-29
EP0553234A4 (el) 1995-08-02
ES2126576T5 (es) 2005-12-01
DE69130482D1 (de) 1998-12-17
DE69130482T2 (de) 1999-05-27

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