GEP201706788B - Method for producing haemophilus influenzae type b antigens - Google Patents

Method for producing haemophilus influenzae type b antigens

Info

Publication number
GEP201706788B
GEP201706788B GEAP201313708A GEAP2013013708A GEP201706788B GE P201706788 B GEP201706788 B GE P201706788B GE AP201313708 A GEAP201313708 A GE AP201313708A GE AP2013013708 A GEAP2013013708 A GE AP2013013708A GE P201706788 B GEP201706788 B GE P201706788B
Authority
GE
Georgia
Prior art keywords
haemophilus influenzae
influenzae type
culture medium
antigens
capsular
Prior art date
Application number
GEAP201313708A
Other languages
English (en)
Inventor
Hir Jérome Le
Pascal Loubiere
Fabien Barbirato
Nicholas Lindley
Original Assignee
Sanofi Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur filed Critical Sanofi Pasteur
Publication of GEP201706788B publication Critical patent/GEP201706788B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/04Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
GEAP201313708A 2012-07-02 2013-07-02 Method for producing haemophilus influenzae type b antigens GEP201706788B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1256329A FR2992656B1 (fr) 2012-07-02 2012-07-02 Procede de production d'antigenes haemophilus influenzae type b

Publications (1)

Publication Number Publication Date
GEP201706788B true GEP201706788B (en) 2017-12-11

Family

ID=47666183

Family Applications (1)

Application Number Title Priority Date Filing Date
GEAP201313708A GEP201706788B (en) 2012-07-02 2013-07-02 Method for producing haemophilus influenzae type b antigens

Country Status (33)

Country Link
US (2) US9556464B2 (https=)
EP (1) EP2885397B1 (https=)
JP (1) JP6347778B2 (https=)
KR (1) KR102051482B1 (https=)
CN (1) CN104583390B (https=)
AU (1) AU2013285306B2 (https=)
BR (1) BR112014033082B1 (https=)
CA (1) CA2878053C (https=)
CR (1) CR20140559A (https=)
CY (1) CY1120465T1 (https=)
DK (1) DK2885397T3 (https=)
ES (1) ES2681993T3 (https=)
FR (1) FR2992656B1 (https=)
GE (1) GEP201706788B (https=)
HR (1) HRP20181206T1 (https=)
HU (1) HUE038865T2 (https=)
IL (1) IL236208A0 (https=)
LT (1) LT2885397T (https=)
MX (1) MX358953B (https=)
NZ (1) NZ702471A (https=)
PE (1) PE20150192A1 (https=)
PH (1) PH12014502730A1 (https=)
PL (1) PL2885397T3 (https=)
PT (1) PT2885397T (https=)
RS (1) RS57495B1 (https=)
RU (1) RU2644246C2 (https=)
SG (1) SG11201408194SA (https=)
SI (1) SI2885397T1 (https=)
SM (1) SMT201800389T1 (https=)
TR (1) TR201810678T4 (https=)
UA (1) UA115787C2 (https=)
WO (1) WO2014006318A1 (https=)
ZA (2) ZA201500028B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2624014C1 (ru) * 2016-04-08 2017-06-30 Федеральное государственное унитарное предприятие "Санкт-Петербургский научно-исследовательский институт вакцин и сывороток и предприятие по производству бактерийных препаратов" Федерального медико-биологического агентства России (ФГУП СПбНИИВС ФМБА России) Штамм haemophilus influenzae spb тип в - высокоактивный продуцент капсульного полисахарида полирибозилрибитолфосфата
CN109922828A (zh) 2016-10-20 2019-06-21 Km生物医药股份公司 使用具有降低了的分子量的PRP的Hib结合疫苗的制造方法
WO2018193475A2 (en) * 2017-04-22 2018-10-25 Biological E Limited An improved method for high level production of crm
RU2704452C1 (ru) * 2019-04-22 2019-10-28 Федеральное государственное унитарное предприятие "Санкт-Петербургский научно-исследовательский институт вакцин и сывороток и предприятие по производству бактерийных препаратов" Федерального медико-биологического агентства Способ получения вакцины гемофильной тип b конъюгированной
CN109975559B (zh) * 2019-04-29 2023-07-11 厦门稀土材料研究所 一种时间分辨荧光定量检测25羟基维生素d的试剂盒及方法
CN111000994A (zh) * 2019-12-26 2020-04-14 北京科兴中维生物技术有限公司 一种液体疫苗组合物及其制备方法与应用
CN112212779B (zh) * 2020-09-04 2022-05-17 厦门大学 一种水凝胶柔性应变传感器的制备方法
WO2022114735A1 (ko) * 2020-11-25 2022-06-02 주식회사 엘지화학 헤모필루스 인플루엔자 타입 b의 prp 항원 정제 공정의 품질 평가 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03183416A (ja) * 1989-12-12 1991-08-09 Shozo Oyama 菌根菌を培養する方法、およびその子実体を取得する方法
FR2791895B1 (fr) * 1999-03-23 2001-06-15 Pasteur Merieux Serums Vacc Utilisation de trehalose pour stabiliser un vaccin liquide
RU2258737C2 (ru) * 2003-09-01 2005-08-20 Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова РАМН Питательная среда для культивирования бактерий haemophilus influenzae типа b
FR2914302A1 (fr) * 2007-03-30 2008-10-03 Sanofi Pasteur Sa Procede de preparation de derives de porphyrine, telle que la protoporphyrine (ix) et intermediaire de synthese
FR2918671B1 (fr) * 2007-07-10 2010-10-15 Sanofi Pasteur Milieu de culture d'haemophilus influenzae type b.
GB0818453D0 (en) 2008-10-08 2008-11-12 Novartis Ag Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
PE20100366A1 (es) * 2008-10-24 2010-05-21 Panacea Biotec Ltd Novedosas composiciones de vacuna con tos ferina acelular asi como el metodo para su elaboracion
TW201129698A (en) * 2009-12-10 2011-09-01 Jgc Corp New cell culture method

Also Published As

Publication number Publication date
PE20150192A1 (es) 2015-02-27
EP2885397B1 (fr) 2018-05-30
CY1120465T1 (el) 2019-07-10
SG11201408194SA (en) 2015-01-29
KR102051482B1 (ko) 2019-12-03
JP6347778B2 (ja) 2018-06-27
WO2014006318A1 (fr) 2014-01-09
RS57495B1 (sr) 2018-10-31
US20170211111A1 (en) 2017-07-27
PL2885397T3 (pl) 2018-10-31
PT2885397T (pt) 2018-07-27
KR20150036311A (ko) 2015-04-07
MX2014014607A (es) 2015-02-12
PH12014502730B1 (en) 2015-02-02
UA115787C2 (uk) 2017-12-26
TR201810678T4 (tr) 2018-08-27
CN104583390A (zh) 2015-04-29
MX358953B (es) 2018-09-10
EP2885397A1 (fr) 2015-06-24
SMT201800389T1 (it) 2018-09-13
LT2885397T (lt) 2018-08-27
BR112014033082A2 (pt) 2017-06-27
PH12014502730A1 (en) 2015-02-02
HK1208493A1 (en) 2016-03-04
ZA201500028B (en) 2016-10-26
NZ702471A (en) 2017-08-25
HUE038865T2 (hu) 2018-12-28
CN104583390B (zh) 2018-07-10
US20150167036A1 (en) 2015-06-18
DK2885397T3 (en) 2018-08-06
RU2644246C2 (ru) 2018-02-08
ZA201500014B (en) 2016-10-26
CA2878053A1 (fr) 2014-01-09
IL236208A0 (en) 2015-01-29
BR112014033082B1 (pt) 2022-02-15
AU2013285306A1 (en) 2015-01-15
HRP20181206T1 (hr) 2018-10-05
RU2015103140A (ru) 2016-08-27
JP2015522272A (ja) 2015-08-06
FR2992656A1 (fr) 2014-01-03
CA2878053C (fr) 2021-07-06
ES2681993T3 (es) 2018-09-17
US9556464B2 (en) 2017-01-31
AU2013285306B2 (en) 2018-10-04
SI2885397T1 (sl) 2018-09-28
CR20140559A (es) 2015-04-06
FR2992656B1 (fr) 2016-10-07
US10144940B2 (en) 2018-12-04

Similar Documents

Publication Publication Date Title
GEP201706788B (en) Method for producing haemophilus influenzae type b antigens
PH12015500497A1 (en) Production method for capsular polysaccharide having pneumococcal serotype
WO2013105802A3 (ko) 자일로즈 이용능이 부여된 코리네박테리움 속 미생물 및 이를 이용한 l-라이신의 생산방법
BR112017021255A2 (pt) microrganismo modificado para a produção otimizada de 2,4-di-hidroxibutirato
MX2018006063A (es) Medios y metodos de fermentacion para producir polisacarido en cultivo celular bacteriano.
MY154509A (en) Re-engineering bacteria for ethanol production
MY189896A (en) Microorganisms of the genus corynebacterium having l-isoleucine producing ability and methods for producing l-isoleucine using the same
MX355904B (es) Microorganismo para producir simultáneamente l-amino ácidos y riboflavina, y método para producir l-amino acidos y riboflavina usando el mismo.
MX2015001780A (es) Microorganismos y métodos para la producción de ácidos grasos y productos derivados de ácidos grasos.
PH12015501138A1 (en) Production of high yields of bacterial polysaccharides
GB2495341B (en) Fermentation methods and their products
MX361324B (es) Metodo de enriquecimiento proteico de la biomasa de microalgas.
MY181203A (en) Microorganism of corynebacterium sp. having enhanced l-lysine producibility and method for producing l-lysine using same
SA515360688B1 (ar) السلالة البكتيرية رودوكوكوس أيثوريفورنز VKM Ac-2610D المنتجة النيتريل هيدراتاز، طريقة لزراعتها وطريقة لإنتاج الأكريلاميد
WO2008093829A1 (ja) L-アミノ酸の製造法
MX345593B (es) Metodo para producir alimento carnico procesado y preparacion de enzimas para la modificacion de alimento carnico procesado.
UA105508C2 (uk) Спосіб одержання вакцини проти clostridium difficile
MY200877A (en) Leuconostoc Mesenteroides Cjlm119 Strain Producing Reduced Amount Of Gas, And Kimchi Production Method Using Same
MY181143A (en) Microorganisms producing l-amino acids and process for producing l-amino acids using the same
WO2014144329A3 (en) Methods of producing protoporphyrin ix and bacterial mutants therefor
WO2015116781A3 (en) Promoters suitable for heterologous gene expression in yeast
MX2016008103A (es) Proceso para producir un polímero beta-glucano y los microorganismos genéticamente útiles en este proceso.
TH153204A (th) วิธีเพื่อผลิตแอนติเจน Haemophilus influenzae ไทป์ b
MY173672A (en) Sap preparation method, microorganism culture method, useful substance producing method and sap component utilization method
UA86891U (uk) Спосіб отримання бактерійного дифтерійного антигену