GB8819308D0 - Triazole antifungal agents - Google Patents

Triazole antifungal agents

Info

Publication number
GB8819308D0
GB8819308D0 GB888819308A GB8819308A GB8819308D0 GB 8819308 D0 GB8819308 D0 GB 8819308D0 GB 888819308 A GB888819308 A GB 888819308A GB 8819308 A GB8819308 A GB 8819308A GB 8819308 D0 GB8819308 D0 GB 8819308D0
Authority
GB
United Kingdom
Prior art keywords
antifungal agents
triazole antifungal
triazole
agents
antifungal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB888819308A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10642109&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB8819308(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Inc filed Critical Pfizer Inc
Priority to GB888819308A priority Critical patent/GB8819308D0/en
Publication of GB8819308D0 publication Critical patent/GB8819308D0/en
Priority to IN634DE1989 priority patent/IN175438B/en
Priority to AU38930/89A priority patent/AU602638B2/en
Priority to PE1989157445A priority patent/PE1591A1/es
Priority to EP89307920A priority patent/EP0357241B1/en
Priority to DE68913105T priority patent/DE68913105T2/de
Priority to AT89307920T priority patent/ATE101600T1/de
Priority to ES89307920T priority patent/ES2062009T4/es
Priority to IL10626289A priority patent/IL106262A/en
Priority to IL9123189A priority patent/IL91231A/en
Priority to MA21863A priority patent/MA21610A1/fr
Priority to APAP/P/1989/000135A priority patent/AP104A/en
Priority to SK4761-89A priority patent/SK476189A3/sk
Priority to IS3499A priority patent/IS1586B/is
Priority to MYPI89001091A priority patent/MY105092A/en
Priority to CS894761A priority patent/CZ284318B6/cs
Priority to RO141245A priority patent/RO108453B1/ro
Priority to OA59624A priority patent/OA09126A/xx
Priority to NO893248A priority patent/NO174101C/no
Priority to NZ230283A priority patent/NZ230283A/xx
Priority to ZA896151A priority patent/ZA896151B/xx
Priority to PL28102089A priority patent/PL162953B1/pl
Priority to PT91440A priority patent/PT91440B/pt
Priority to AR89314635A priority patent/AR246963A1/es
Priority to PL89297228A priority patent/PL163756B1/pl
Priority to CA000608083A priority patent/CA1341325C/en
Priority to JP1209513A priority patent/JPH0786100B2/ja
Priority to HU894151A priority patent/HU205348B/hu
Priority to MX1716989A priority patent/MX17169A/es
Priority to YU158789A priority patent/YU47093B/sh
Priority to DK198903945A priority patent/DK172471B1/da
Priority to BG89519A priority patent/BG60865B1/bg
Priority to FI893809A priority patent/FI96859C/fi
Priority to US07/392,686 priority patent/US5116844A/en
Priority to IE258289A priority patent/IE61412B1/en
Priority to SU894614663A priority patent/RU1836366C/ru
Priority to KR1019890011503A priority patent/KR930002729B1/ko
Priority to CN89106679A priority patent/CN1029231C/zh
Priority to EG39389A priority patent/EG19640A/xx
Priority to DD89331760A priority patent/DD284010A5/de
Priority to US07/845,986 priority patent/US5206364A/en
Priority to SU925010979A priority patent/RU2095358C1/ru
Priority to US08/026,671 priority patent/US5364938A/en
Priority to IL106262A priority patent/IL106262A0/xx
Priority to LVP-93-1223A priority patent/LV10714B/lv
Priority to JP6307468A priority patent/JP2713394B2/ja
Priority to HU95P/P00436P priority patent/HU211511A9/hu
Priority to CY196897A priority patent/CY1968A/xx
Priority to HK97101863A priority patent/HK1000320A1/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/08Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
GB888819308A 1988-08-13 1988-08-13 Triazole antifungal agents Pending GB8819308D0 (en)

Priority Applications (49)

Application Number Priority Date Filing Date Title
GB888819308A GB8819308D0 (en) 1988-08-13 1988-08-13 Triazole antifungal agents
IN634DE1989 IN175438B (https=) 1988-08-13 1989-07-18
AU38930/89A AU602638B2 (en) 1988-08-13 1989-07-24 Triazole antifungal agents
PE1989157445A PE1591A1 (es) 1988-08-13 1989-07-31 Procedimiento para la preparacion de agentes tiazoles antifungicos
EP89307920A EP0357241B1 (en) 1988-08-13 1989-08-03 Triazole antifungal agents
DE68913105T DE68913105T2 (de) 1988-08-13 1989-08-03 Triazole als schimmelhemmende Mittel.
AT89307920T ATE101600T1 (de) 1988-08-13 1989-08-03 Triazole als schimmelhemmende mittel.
ES89307920T ES2062009T4 (es) 1988-08-13 1989-08-03 Agentes antifungicos derivados de triazol
IL10626289A IL106262A (en) 1988-08-13 1989-08-07 Intermediates to triazole antifungal agents
IL9123189A IL91231A (en) 1988-08-13 1989-08-07 2-Phenyl-3-heteroaryl-1-(1h-1,2,4-triazol-1-yl) alkan-2-ol derivatives and pharmaceutical compositions containing them
MA21863A MA21610A1 (fr) 1988-08-13 1989-08-08 Procede de production de composes triazoliques .
APAP/P/1989/000135A AP104A (en) 1988-08-13 1989-08-10 Triazole antifungal agents.
SK4761-89A SK476189A3 (en) 1988-08-13 1989-08-10 Triazole derivatives, process for their preparation, intermediates of such process, use and a pharmaceutical composition
IS3499A IS1586B (is) 1988-08-13 1989-08-10 Aðferðir við framleiðslu á triazoleefni gegn sveppum og gerlum og myndun þeirra
MYPI89001091A MY105092A (en) 1988-08-13 1989-08-10 Triazole antifungal agents.
CS894761A CZ284318B6 (cs) 1988-08-13 1989-08-10 Triazolové deriváty, způsob jejich přípravy a použití a meziprodukty tohoto postupu
RO141245A RO108453B1 (ro) 1988-08-13 1989-08-11 Derivati de 1h-1,2,4 triazol, procedee si intermediari pentru prepararea acestora
OA59624A OA09126A (fr) 1988-08-13 1989-08-11 Procédé de production de composés triazoliques.
NO893248A NO174101C (no) 1988-08-13 1989-08-11 Analogifremgangsmåte ved fremstilling av terapeutisk aktive triazolderivater
NZ230283A NZ230283A (en) 1988-08-13 1989-08-11 Triazole derivatives containing a second nitrogen containing ring
ZA896151A ZA896151B (en) 1988-08-13 1989-08-11 Triazole antifungal agents
PL28102089A PL162953B1 (pl) 1988-08-13 1989-08-11 S p o s ó b w y t w a r z a n i a n o w y c h p o c h o d n y c h t r ia z o l u PL PL PL
PT91440A PT91440B (pt) 1988-08-13 1989-08-11 Processo para a preparacao de agentes anti-fungicos de triazole
AR89314635A AR246963A1 (es) 1988-08-13 1989-08-11 Un procedimiento para la preparacion de nuevos derivados de triazol.
PL89297228A PL163756B1 (pl) 1988-08-13 1989-08-11 Sposób wytwarzania nowych pochodnych triazolu PL PL PL
CA000608083A CA1341325C (en) 1988-08-13 1989-08-11 Triazole antifungal agents
JP1209513A JPH0786100B2 (ja) 1988-08-13 1989-08-11 トリアゾール抗真菌剤
HU894151A HU205348B (en) 1988-08-13 1989-08-11 Process for producing triazole derivatives and pharmaceutical compositions comprising such compounds as active ingredient
MX1716989A MX17169A (es) 1988-08-13 1989-08-11 Proceso para la preparacion de derivados de triazol y producto obtenido
YU158789A YU47093B (sh) 1988-08-13 1989-08-11 Novi triazoli i postupak za njihovo dobijanje
DK198903945A DK172471B1 (da) 1988-08-13 1989-08-11 3-Heterocyclyl-2-phenyl-1-(1H-1,2,4-triazol-1-yl)-alkan-2-ol-forbindelser, forbindelserne til anvendelse som lægemidler, fa
BG89519A BG60865B1 (bg) 1988-08-13 1989-08-11 Триазолови фунгицидни съединения и метод за получаването им
FI893809A FI96859C (fi) 1988-08-13 1989-08-11 Menetelmä terapeuttisesti käyttökelpoisten fungisidisten triatsoliyhdisteiden valmistamiseksi
US07/392,686 US5116844A (en) 1988-08-13 1989-08-11 Triazole antifungal agents
IE258289A IE61412B1 (en) 1988-08-13 1989-08-11 Triazole antifungal agents
SU894614663A RU1836366C (ru) 1988-08-13 1989-08-11 Способ получени производных 1,2,4-триазола или их фармацевтически приемлемых солей
KR1019890011503A KR930002729B1 (ko) 1988-08-13 1989-08-12 트리아졸 항진균제
CN89106679A CN1029231C (zh) 1988-08-13 1989-08-12 三唑类抗霉菌剂的制备方法
EG39389A EG19640A (en) 1988-08-13 1989-08-13 Process for preparing of triazole antifungal agents
DD89331760A DD284010A5 (de) 1988-08-13 1989-08-14 Verfahren zum herstellen von gengen pilzbefall wirksamen triazol-verbindungen
US07/845,986 US5206364A (en) 1988-08-13 1992-03-04 Triazole antifungal agents
SU925010979A RU2095358C1 (ru) 1988-08-13 1992-03-05 Производные 1,2,4-триазола или их фармацевтически приемлемые соли, фармацевтическая композиция и промежуточные соединения
US08/026,671 US5364938A (en) 1988-08-13 1993-03-04 Triazole antifungal agents
IL106262A IL106262A0 (en) 1988-08-13 1993-07-07 Intermediates to triazole antifungal agents
LVP-93-1223A LV10714B (en) 1988-08-13 1993-11-15 Triazole compounds
JP6307468A JP2713394B2 (ja) 1988-08-13 1994-12-12 トリアゾール化合物合成用中間体
HU95P/P00436P HU211511A9 (en) 1988-08-13 1995-06-26 Triazole antifungal agents
CY196897A CY1968A (en) 1988-08-13 1997-09-05 Triazole antifungal agents
HK97101863A HK1000320A1 (en) 1988-08-13 1997-09-26 Triazole antifungal agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888819308A GB8819308D0 (en) 1988-08-13 1988-08-13 Triazole antifungal agents

Publications (1)

Publication Number Publication Date
GB8819308D0 true GB8819308D0 (en) 1988-09-14

Family

ID=10642109

Family Applications (1)

Application Number Title Priority Date Filing Date
GB888819308A Pending GB8819308D0 (en) 1988-08-13 1988-08-13 Triazole antifungal agents

Country Status (39)

Country Link
US (2) US5116844A (https=)
EP (1) EP0357241B1 (https=)
JP (2) JPH0786100B2 (https=)
KR (1) KR930002729B1 (https=)
CN (1) CN1029231C (https=)
AP (1) AP104A (https=)
AR (1) AR246963A1 (https=)
AU (1) AU602638B2 (https=)
BG (1) BG60865B1 (https=)
CA (1) CA1341325C (https=)
CY (1) CY1968A (https=)
CZ (1) CZ284318B6 (https=)
DD (1) DD284010A5 (https=)
DE (1) DE68913105T2 (https=)
DK (1) DK172471B1 (https=)
ES (1) ES2062009T4 (https=)
FI (1) FI96859C (https=)
GB (1) GB8819308D0 (https=)
HK (1) HK1000320A1 (https=)
HU (2) HU205348B (https=)
IE (1) IE61412B1 (https=)
IL (1) IL91231A (https=)
IN (1) IN175438B (https=)
IS (1) IS1586B (https=)
LV (1) LV10714B (https=)
MA (1) MA21610A1 (https=)
MX (1) MX17169A (https=)
MY (1) MY105092A (https=)
NO (1) NO174101C (https=)
NZ (1) NZ230283A (https=)
OA (1) OA09126A (https=)
PE (1) PE1591A1 (https=)
PL (2) PL162953B1 (https=)
PT (1) PT91440B (https=)
RO (1) RO108453B1 (https=)
RU (2) RU1836366C (https=)
SK (1) SK476189A3 (https=)
YU (1) YU47093B (https=)
ZA (1) ZA896151B (https=)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU620342B2 (en) * 1987-09-24 1992-02-20 Philip Morris Products Inc. Smoking compositions containing a heteroaromatic flavorant-release additive
DK105189A (da) * 1988-03-04 1989-09-05 Sankyo Co Triazolderivater og fremgangsmaade til fremstilling deraf samt fungicide midler indeholdende derivaterne
GB9002375D0 (en) * 1990-02-02 1990-04-04 Pfizer Ltd Triazole antifungal agents
US5278175A (en) * 1990-02-02 1994-01-11 Pfizer Inc. Triazole antifungal agents
GB9107055D0 (en) * 1991-04-04 1991-05-22 Pfizer Ltd Triazole antifungal agents
US5493024A (en) * 1991-04-11 1996-02-20 Dowelanco 3,4,N-trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insectioides
GB9121456D0 (en) * 1991-10-10 1991-11-27 Pfizer Ltd Triazole antifungal agents
GB9317491D0 (en) * 1993-08-23 1993-10-06 Fujisawa Pharmaceutical Co New compound and a process for preparation thereof
SE508401C2 (sv) * 1993-06-09 1998-10-05 Sca Hygiene Prod Ab Absorberande struktur och absorberande alster, som innefattar strukturen ifråga
NZ270418A (en) * 1994-02-07 1997-09-22 Eisai Co Ltd Polycyclic triazole & imidazole derivatives, antifungal compositions
CA2145458A1 (en) * 1994-03-28 1995-09-29 Hiroki Kodama Triazole compound and production process and use thereof
GB9512961D0 (en) * 1995-06-26 1995-08-30 Pfizer Ltd Antifungal agents
CA2180091A1 (en) * 1995-07-08 1997-01-09 Hiroki Kodama Optically active triazole derivative, process for producing the same, antifungal agent, and method for using the same
ES2107376B1 (es) * 1995-08-02 1998-07-01 Uriach & Cia Sa J Nuevos derivados de pirimidona con actividad antifungica.
BR9606547A (pt) * 1995-08-02 1997-10-14 Uriach & Cia Sa J Novos derivados de pirimidona com atividade fungicida
BR9606546A (pt) * 1995-08-02 1998-07-14 Uriach & Cia Sa J Novas carboxamidas com atividade fungicida
GB9516121D0 (en) 1995-08-05 1995-10-04 Pfizer Ltd Organometallic addition to ketones
GB9605705D0 (en) * 1996-03-19 1996-05-22 Pfizer Ltd Therapeutic agents
US7193083B2 (en) * 1996-07-26 2007-03-20 Pfizer, Inc. Preparation of triazoles by organometallic addition to ketones and intermediates therefor
US6699853B2 (en) 1997-06-16 2004-03-02 Hoechst Schering Agrevo Gmbh 4-haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, processes for their preparation, compositions comprising them, and their use as pesticides
DE19725450A1 (de) 1997-06-16 1998-12-17 Hoechst Schering Agrevo Gmbh 4-Haloalkyl-3-heterocyclylpyridine und 4-Haloalkyl-5-heterocyclylpyrimidine, Verfahren zu ihrer Herstellung, sie enthaltende Mittel und ihre Verwendung als Schädlingsbekämpfungsmittel
GB9713149D0 (en) * 1997-06-21 1997-08-27 Pfizer Ltd Pharmaceutical formulations
US6362172B2 (en) * 2000-01-20 2002-03-26 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
ES2159488B1 (es) 2000-03-07 2002-04-16 Uriach & Cia Sa J Procedimiento para la preparacion de derivados de pirimidona con actividad antifungica.
FR2814073B1 (fr) * 2000-09-21 2005-06-24 Yang Ji Chemical Company Ltd Composition pharmaceutique antifongique et/ou antiparasitaire et nouveaux derives de l'indole a titre de principes actifs d'une telle composition
KR100572996B1 (ko) * 2003-08-12 2006-04-25 한국화학연구원 불소화 비닐 에테르 측쇄기를 갖는 아졸계 살균제 화합물및 그의 제조방법
RU2256655C1 (ru) * 2004-01-27 2005-07-20 Закрытое акционерное общество Фирма "Август" Способ получения 1-(4-хлорфенил)-3-(1,2,4-триазол-1-ил-метил)-4,4-диметилпентан-3-ола
RU2295958C1 (ru) * 2005-07-04 2007-03-27 Федеральное государственное унитарное предприятие "Центр по химии лекарственных средств" (ФГУП ЦХЛС-ВНИХФИ) Фармацевтический состав для лечения грибковых заболеваний и способ его получения
AR061889A1 (es) 2006-07-13 2008-10-01 Medichem Sa Proceso mejorado para la preparacion de voriconazol
WO2008021049A2 (en) 2006-08-07 2008-02-21 Stiefel Laboratories, Inc. Crystalline antifungal compounds
US20110224232A1 (en) * 2008-05-06 2011-09-15 Board Of Regents, The University Of Texas System Treatment of Pulmonary Fungal Infection With Voriconazole via Inhalation
BR112012000170A2 (pt) * 2009-07-08 2019-09-24 Bayer Cropscience Ag derivados de fenil (oxi/tio) alcanol substituídos
WO2011064558A2 (en) 2009-11-30 2011-06-03 Cipla Limited Pharmaceutical composition
WO2011110198A1 (en) 2010-03-10 2011-09-15 Synthron B.V. A process for making voriconazole
AU2011242562B2 (en) * 2010-04-24 2016-10-13 Mycovia Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
US9056855B2 (en) 2010-10-28 2015-06-16 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
RU2478106C2 (ru) * 2010-11-25 2013-03-27 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Казанский (Приволжский) Федеральный Университет" (ФГАОУ ВПО КФУ) СОЕДИНЕНИЯ НА ОСНОВЕ КОМПЛЕКСОВ ГИПЕРРАЗВЕТВЛЕННЫХ ПОЛИМЕРОВ Boltorn H, ОБЛАДАЮЩИЕ АНТИКАНДИДОЗНОЙ АКТИВНОСТЬЮ, И СПОСОБ ИХ ПОЛУЧЕНИЯ
WO2012114273A1 (en) 2011-02-21 2012-08-30 Ranbaxy Laboratories Limited An improved process for the preparation of voriconazole and intermediates thereof
PL2720723T3 (pl) 2011-06-15 2018-10-31 Synthon Bv Stabilizowana kompozycja worykonazolu
AU2012273100B2 (en) * 2011-06-19 2017-05-25 Viamet Pharmaceuticals (NC), Inc. Metalloenzyme inhibitor compounds
KR20140040235A (ko) * 2011-06-19 2014-04-02 비아멧 파마슈티컬즈, 인코포레이티드 금속효소 억제제 화합물
US8940735B2 (en) * 2011-06-23 2015-01-27 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
TWI658039B (zh) * 2011-07-08 2019-05-01 維愛美製藥公司 金屬酶抑制劑化合物
TWI646088B (zh) * 2012-03-16 2019-01-01 維愛美製藥公司 金屬酶抑制劑化合物
CA2872958A1 (en) 2012-05-11 2013-11-14 Cipla Limited Pharmaceutical composition
CN102796087B (zh) * 2012-09-04 2015-04-15 西南大学 香豆素三唑醇及其制备方法和用途
US20150246898A1 (en) * 2012-09-12 2015-09-03 Dow Agrosciences Llc Metalloenzyme inhibitor compounds
IN2015DN02877A (https=) * 2012-10-15 2015-09-11 Pfizer Ireland Pharmaceuticals
US9447073B2 (en) 2013-05-28 2016-09-20 Viamet Pharmaceuticals, Inc. Fungicidal compositions
RU2563811C1 (ru) * 2014-08-08 2015-09-20 Федеральное государственное бюджетное учреждение науки Институт химической физики им. Н.Н. Семенова Российской академии наук (ИХФ РАН) Фармацевтическая композиция для лечения грибковых заболеваний
EP3201188A1 (en) 2014-10-02 2017-08-09 Bayer CropScience Aktiengesellschaft Novel triazole derivatives useful as fungicides
CR20170574A (es) 2015-05-18 2018-07-19 Viamet Pharmaceuticals Inc Compuestos antifíngicos
BR112020025987A2 (pt) 2018-06-21 2021-03-23 Yumanity Therapeutics, Inc. composições e métodos para tratamento e prevenção de distúrbios neurológicos
CN115650925B (zh) * 2022-09-07 2024-09-24 中国人民解放军海军军医大学 一种三氮唑醇类衍生物及其制备方法和应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0158741A3 (en) * 1980-11-19 1986-02-12 Imperial Chemical Industries Plc Intermediates for fungicidal triazole and imidazole compounds
US4510148A (en) * 1982-06-12 1985-04-09 Pfizer Inc. 2-Heterocyclic-1,3-bis(1H-1,2,4-triazol-1-yl)-propan-2-ols as antifungal agents
DE3228870A1 (de) * 1982-08-03 1984-02-09 Bayer Ag, 5090 Leverkusen Diazolyl-alkanole, verfahren zu ihrer herstellung und ihre verwendung als antimykotische mittel
DE3242252A1 (de) * 1982-11-15 1984-05-17 Bayer Ag, 5090 Leverkusen Heterocyclisch substituierte hydroxyalkyl-azolyl-derivate
DE3242236A1 (de) * 1982-11-15 1984-05-17 Bayer Ag, 5090 Leverkusen "antimykotische mittel"
GB8304282D0 (en) * 1983-02-16 1983-03-23 Pfizer Ltd Antifungal agents
DE3307218A1 (de) * 1983-03-02 1984-09-06 Bayer Ag, 5090 Leverkusen Substituierte diazolylalkyl-carbinole, verfahren zu ihrer herstellung und ihre verwendung als antimykotische mittel
GB8306351D0 (en) * 1983-03-08 1983-04-13 Ici Plc Azole fungicides
GB8307232D0 (en) * 1983-03-16 1983-04-20 Pfizer Ltd Antifungal agents
DK159205C (da) * 1983-03-16 1991-03-04 Pfizer Bis(triazol)alkanol-forbindelser, anvendelse af disse, farmaceutiske praeparater og landbrugsfungicider indeholdende disse og fremgangsmaade til behandling af planter eller froe, som har en svampeinfektion
GB8313235D0 (en) * 1983-05-13 1983-06-22 Pfizer Ltd Antifungal agents
DE3325313A1 (de) * 1983-07-13 1985-01-31 Bayer Ag, 5090 Leverkusen Fungizide mittel, deren herstellung und verwendung
US4483863A (en) * 1984-01-20 1984-11-20 Pfizer Inc. Triazole antifungal agents
IE58738B1 (en) * 1984-09-05 1993-11-03 Ici Plc Antifungal azole compounds
DE3440117A1 (de) * 1984-11-02 1986-05-15 Bayer Ag, 5090 Leverkusen Substituierte azolylcyclopropyl-azolylmethyl-carbinol-derivate
GB8506619D0 (en) * 1985-03-14 1985-04-17 Pfizer Ltd Triazole antifungal agents
ZA874485B (en) * 1986-06-23 1989-02-22 Du Pont Antifungal carbinols
DE3813841A1 (de) * 1987-06-03 1988-12-15 Bayer Ag Heterocyclische hydroxyethylazole
GB8716651D0 (en) * 1987-07-15 1987-08-19 Ici Plc 2-propanol derivatives
DK105189A (da) * 1988-03-04 1989-09-05 Sankyo Co Triazolderivater og fremgangsmaade til fremstilling deraf samt fungicide midler indeholdende derivaterne

Also Published As

Publication number Publication date
RU1836366C (ru) 1993-08-23
NZ230283A (en) 1991-02-26
ZA896151B (en) 1991-03-27
MY105092A (en) 1994-08-30
IL91231A0 (en) 1990-03-19
MA21610A1 (fr) 1990-04-01
DE68913105D1 (de) 1994-03-24
AU602638B2 (en) 1990-10-18
SK280775B6 (sk) 2000-07-11
AR246963A1 (es) 1994-10-31
HU205348B (en) 1992-04-28
KR900003157A (ko) 1990-03-23
PL163756B1 (pl) 1994-04-29
ES2062009T3 (es) 1994-12-16
IE892582L (en) 1990-02-13
DD284010A5 (de) 1990-10-31
JPH0786100B2 (ja) 1995-09-20
BG89519A (bg) 1993-12-24
DE68913105T2 (de) 1994-05-26
FI893809L (fi) 1990-02-14
IL91231A (en) 1994-08-26
RO108453B1 (ro) 1994-05-31
CN1029231C (zh) 1995-07-05
DK172471B1 (da) 1998-09-07
HU211511A9 (en) 1995-11-28
IS3499A7 (is) 1990-02-14
FI96859C (fi) 1996-09-10
HUT52089A (en) 1990-06-28
PT91440B (pt) 1995-05-04
BG60865B1 (bg) 1996-05-31
EP0357241B1 (en) 1994-02-16
IN175438B (https=) 1995-06-17
ES2062009T4 (es) 2006-07-01
YU158789A (en) 1991-04-30
FI893809A0 (fi) 1989-08-11
CY1968A (en) 1997-09-05
JPH07173154A (ja) 1995-07-11
DK394589D0 (da) 1989-08-11
YU47093B (sh) 1994-12-28
KR930002729B1 (ko) 1993-04-09
US5116844A (en) 1992-05-26
HK1000320A1 (en) 1998-02-27
MX17169A (es) 1993-08-01
LV10714B (en) 1995-12-20
OA09126A (fr) 1991-10-31
CZ284318B6 (cs) 1998-10-14
PL162953B1 (pl) 1994-01-31
NO174101B (no) 1993-12-06
CN1040795A (zh) 1990-03-28
IS1586B (is) 1996-03-01
AU3893089A (en) 1990-03-22
CA1341325C (en) 2001-12-11
LV10714A (lv) 1995-06-20
EP0357241A1 (en) 1990-03-07
SK476189A3 (en) 2000-07-11
PT91440A (pt) 1990-03-08
AP104A (en) 1990-11-02
JPH02104583A (ja) 1990-04-17
NO893248L (no) 1990-02-14
PE1591A1 (es) 1991-03-16
FI96859B (fi) 1996-05-31
CZ476189A3 (cs) 1998-09-16
AP8900135A0 (en) 1989-10-31
US5364938A (en) 1994-11-15
NO174101C (no) 1994-03-16
NO893248D0 (no) 1989-08-11
RU2095358C1 (ru) 1997-11-10
IE61412B1 (en) 1994-11-02
DK394589A (da) 1990-02-14
JP2713394B2 (ja) 1998-02-16

Similar Documents

Publication Publication Date Title
CY1968A (en) Triazole antifungal agents
AP9000237A0 (en) Triazole antifungal agents
EG18737A (en) Herbicidal triazolinones
ZA892043B (en) Substituted triazoles
DE3463655D1 (en) Triazole antifungal agents
GB8729083D0 (en) Triazole antifungal agents
GB9107055D0 (en) Triazole antifungal agents
GB8817315D0 (en) Triazole antifungal agents
DE3463269D1 (en) Triazole antifungal agents
GB8312624D0 (en) Triazole antifungal agents
DE3461637D1 (en) Triazole antifungal agents
ZA891757B (en) Fungicidal imidazolylmethyloxiranes
ZA841894B (en) Triazole antifungal agents
DE3474141D1 (en) Triazole antifungal agents
ZA895177B (en) Triazole insecticides
GB9122829D0 (en) Antifungal agent
IE883681L (en) Triazole antifungal agents
GB8321527D0 (en) Triazole antifungal agents
IE892349L (en) Triazole antifungal agents
GB8721901D0 (en) Triazole antifungal agents
GB8420583D0 (en) Triazole antifungal agents
GB8401738D0 (en) Triazole antifungal agents
GB8403279D0 (en) Triazole antifungal agents
IE880418L (en) Antifungal 2-anilinothiazolines
IE883753L (en) Azoles