GB8517923D0 - Distamycin derivatives - Google Patents

Distamycin derivatives

Info

Publication number
GB8517923D0
GB8517923D0 GB858517923A GB8517923A GB8517923D0 GB 8517923 D0 GB8517923 D0 GB 8517923D0 GB 858517923 A GB858517923 A GB 858517923A GB 8517923 A GB8517923 A GB 8517923A GB 8517923 D0 GB8517923 D0 GB 8517923D0
Authority
GB
United Kingdom
Prior art keywords
distamycin derivatives
distamycin
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB858517923A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CN198585103908A priority Critical patent/CN85103908A/zh
Priority to GB858517923A priority patent/GB8517923D0/en
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of GB8517923D0 publication Critical patent/GB8517923D0/en
Priority to US06/783,508 priority patent/US4738980A/en
Priority to SE8603099A priority patent/SE468594B/sv
Priority to AT0188786A priority patent/AT386822B/de
Priority to HU862903A priority patent/HU198087B/hu
Priority to IL79401A priority patent/IL79401A/xx
Priority to AU60203/86A priority patent/AU584723B2/en
Priority to ES8600291A priority patent/ES2000346A6/es
Priority to NZ216828A priority patent/NZ216828A/xx
Priority to NL8601838A priority patent/NL8601838A/xx
Priority to IE187486A priority patent/IE59275B1/en
Priority to SU864027842A priority patent/SU1535378A3/ru
Priority to BE0/216923A priority patent/BE905109A/fr
Priority to NO862861A priority patent/NO169014C/no
Priority to PH34013A priority patent/PH23459A/en
Priority to PT82985A priority patent/PT82985B/pt
Priority to GR861840A priority patent/GR861840B/el
Priority to FR868610295A priority patent/FR2585019B1/fr
Priority to IT8621124A priority patent/IT1213103B/it
Priority to CH2821/86A priority patent/CH671958A5/de
Priority to JP61164878A priority patent/JPH0780842B2/ja
Priority to ZA865262A priority patent/ZA865262B/xx
Priority to DE3623853A priority patent/DE3623853C2/de
Priority to DK335886A priority patent/DK335886A/da
Priority to KR1019860005716A priority patent/KR940003495B1/ko
Priority to CA000513756A priority patent/CA1247627A/en
Priority to GB8617293A priority patent/GB2178037B/en
Priority to CS865411A priority patent/CZ277823B6/cs
Priority to CN86104774A priority patent/CN1026984C/zh
Priority to FI862960A priority patent/FI82929C/fi
Priority to SU874203631A priority patent/SU1538893A3/ru
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
GB858517923A 1985-07-16 1985-07-16 Distamycin derivatives Pending GB8517923D0 (en)

Priority Applications (32)

Application Number Priority Date Filing Date Title
CN198585103908A CN85103908A (zh) 1985-07-16 1985-06-08 制备4′-表多克索红菌素的新方法
GB858517923A GB8517923D0 (en) 1985-07-16 1985-07-16 Distamycin derivatives
US06/783,508 US4738980A (en) 1985-07-16 1985-10-03 Distamycin derivatives and process for their preparation
SE8603099A SE468594B (sv) 1985-07-16 1986-07-11 Distamycinderivat, foerfarande foer deras framstaellning och en farmaceutisk komposition
AT0188786A AT386822B (de) 1985-07-16 1986-07-11 Verfahren zur herstellung von neuen pyrrolderivaten
HU862903A HU198087B (en) 1985-07-16 1986-07-14 Process for producing distamycin derivatives or poly-pyrrole-2-carboxamido derivatives and pharmaceutical compositions comprising these compounds
IE187486A IE59275B1 (en) 1985-07-16 1986-07-14 Distamycin derivatives and process for their preparation
IL79401A IL79401A (en) 1985-07-16 1986-07-14 Distamycin derivatives,their preparation and pharmaceutical compositions containing them
AU60203/86A AU584723B2 (en) 1985-07-16 1986-07-14 Distamycin derivatives and process for their preparation
ES8600291A ES2000346A6 (es) 1985-07-16 1986-07-14 Un procedimiento para la preparacion de derivados de distamicina
NZ216828A NZ216828A (en) 1985-07-16 1986-07-14 Distamycin derivatives and pharmaceutical compositions
NL8601838A NL8601838A (nl) 1985-07-16 1986-07-14 Distamycinederivaten, werkwijze voor de bereiding ervan, alsmede farmaceutische preparaten, die deze derivaten bevatten.
CA000513756A CA1247627A (en) 1985-07-16 1986-07-15 Distamycin derivatives and process for their preparation
NO862861A NO169014C (no) 1985-07-16 1986-07-15 Analogifremgangsmaate for fremstilling av terapeutisk aktive distamycinderivater
DE3623853A DE3623853C2 (de) 1985-07-16 1986-07-15 Distamycinderivate und Verfahren zu deren Herstellung
SU864027842A SU1535378A3 (ru) 1985-07-16 1986-07-15 Способ получени гидрохлоридов производных дистамицина А
PH34013A PH23459A (en) 1985-07-16 1986-07-15 Distamycin derivatives and process for their preparation
PT82985A PT82985B (pt) 1985-07-16 1986-07-15 Processo para a preparacao de derivados de distamicina e de composicoes farmaceuticas que os contem
GR861840A GR861840B (en) 1985-07-16 1986-07-15 Process for the preparation of distamycin derivatives
FR868610295A FR2585019B1 (fr) 1985-07-16 1986-07-15 Derives de distamycine et leur procede de fabrication
IT8621124A IT1213103B (it) 1985-07-16 1986-07-15 Derivati della distamicina eprocedimento per la loro preparazione.!
CH2821/86A CH671958A5 (enExample) 1985-07-16 1986-07-15
JP61164878A JPH0780842B2 (ja) 1985-07-16 1986-07-15 デイスタマイシン誘導体およびそれらの製造方法
ZA865262A ZA865262B (en) 1985-07-16 1986-07-15 Distamycin derivatives and process for their preparation
BE0/216923A BE905109A (fr) 1985-07-16 1986-07-15 Derives de distamycine et leur procede de fabrication.
DK335886A DK335886A (da) 1985-07-16 1986-07-15 Distamycinderivat og fremgangsmaade til fremstilling deraf
KR1019860005716A KR940003495B1 (ko) 1985-07-16 1986-07-15 디스타마이신 a유도체의 제조방법
FI862960A FI82929C (fi) 1985-07-16 1986-07-16 Foerfarande foer framstaellning av terapeutiskt anvaendbara distamycinderivat.
GB8617293A GB2178037B (en) 1985-07-16 1986-07-16 Distamycin derivatives and process for their preparation
CS865411A CZ277823B6 (en) 1985-07-16 1986-07-16 Distamycin derivatives and process for preparing thereof
CN86104774A CN1026984C (zh) 1985-07-16 1986-07-16 偏端霉素衍生物的制备方法
SU874203631A SU1538893A3 (ru) 1985-07-16 1987-11-11 Способ получени гидрохлорида N-деформил-N [N,N -бис(2-хлорэтил)]дистамицина А

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858517923A GB8517923D0 (en) 1985-07-16 1985-07-16 Distamycin derivatives

Publications (1)

Publication Number Publication Date
GB8517923D0 true GB8517923D0 (en) 1985-08-21

Family

ID=10582358

Family Applications (2)

Application Number Title Priority Date Filing Date
GB858517923A Pending GB8517923D0 (en) 1985-07-16 1985-07-16 Distamycin derivatives
GB8617293A Expired GB2178037B (en) 1985-07-16 1986-07-16 Distamycin derivatives and process for their preparation

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB8617293A Expired GB2178037B (en) 1985-07-16 1986-07-16 Distamycin derivatives and process for their preparation

Country Status (29)

Country Link
US (1) US4738980A (enExample)
JP (1) JPH0780842B2 (enExample)
KR (1) KR940003495B1 (enExample)
CN (2) CN85103908A (enExample)
AT (1) AT386822B (enExample)
AU (1) AU584723B2 (enExample)
BE (1) BE905109A (enExample)
CA (1) CA1247627A (enExample)
CH (1) CH671958A5 (enExample)
CZ (1) CZ277823B6 (enExample)
DE (1) DE3623853C2 (enExample)
DK (1) DK335886A (enExample)
ES (1) ES2000346A6 (enExample)
FI (1) FI82929C (enExample)
FR (1) FR2585019B1 (enExample)
GB (2) GB8517923D0 (enExample)
GR (1) GR861840B (enExample)
HU (1) HU198087B (enExample)
IE (1) IE59275B1 (enExample)
IL (1) IL79401A (enExample)
IT (1) IT1213103B (enExample)
NL (1) NL8601838A (enExample)
NO (1) NO169014C (enExample)
NZ (1) NZ216828A (enExample)
PH (1) PH23459A (enExample)
PT (1) PT82985B (enExample)
SE (1) SE468594B (enExample)
SU (2) SU1535378A3 (enExample)
ZA (1) ZA865262B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE468642B (sv) * 1985-07-16 1993-02-22 Erba Farmitalia Poly-4-aminopyrrol-2-karboxamidoderivat och foerfarande foer deras framstaellning och en farmaceutisk komposition
US5310752A (en) * 1986-05-20 1994-05-10 Farmitalia Carlo Erba Spa Site specific alkylating agents
US5049579A (en) * 1986-05-20 1991-09-17 Farmitalia Carlo Erba, S.R.L. Site specific alkylating agents
GB8612218D0 (en) * 1986-05-20 1986-06-25 Erba Farmitalia Site specific alkylating agents
GB8906709D0 (en) * 1989-03-23 1989-05-10 Creighton Andrew M Acryloyl substituted pyrrole derivatives
AU1224392A (en) * 1991-02-06 1992-09-07 Synphar Laboratories, Inc. Oligopeptide antiretroviral agents
IT1262921B (it) * 1992-01-10 1996-07-22 Federico Arcamone Agenti antitumorali analoghi di oligopeptidi pirrol-amidinici retroversi processi di preparazione e prodotti farmaceutici che li contengono
DE4205948C2 (de) * 1992-02-24 1996-10-31 Mannesmann Ag Farbbandkassette für ein endloses Farbband
US5273991A (en) * 1992-07-29 1993-12-28 Research Corporation Technologies, Inc. Imidazole-containing compositions and methods of use thereof analogs of distamycin
US5629348A (en) * 1994-11-14 1997-05-13 Nzym, Inc. Methods and compositions for treating septoria infections
US5637621A (en) * 1994-11-14 1997-06-10 Nzym, Inc. Methods and compositions for treating Botrytis infections
WO1996015104A2 (en) * 1994-11-14 1996-05-23 Nzym, Inc. Methods and compositions for treating phytopathogenic fungi infections
DE19805431A1 (de) * 1998-02-11 1999-08-12 Merck Patent Gmbh Heteroaromatische Oligoamide als Affinitätsliganden
US7078536B2 (en) * 2001-03-14 2006-07-18 Genesoft Pharmaceuticals, Inc. Charged compounds comprising a nucleic acid binding moiety and uses therefor
CN1427839A (zh) * 2000-03-16 2003-07-02 根索福特股份有限公司 含有核酸结合部分的带电荷化合物及其用途
GB0015447D0 (en) * 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents
ITTO20010633A1 (it) * 2001-07-02 2003-01-02 Univ Ferrara Nuovo impiego di poliammidi eterocicliche e benzoeterocicliche strutturalmente correlate all'antibiotico naturale distamicina a.
EP1539151B1 (en) 2002-08-02 2009-03-18 Genesoft Pharmaceuticals, Inc. Biaryl compounds having anti-infective activity
WO2004039318A2 (en) * 2002-10-25 2004-05-13 Genesoft Pharmaceuticals, Inc. Anti-infective biaryl compounds
CA2508769A1 (en) * 2002-12-10 2004-06-24 Oscient Pharmaceuticals Corporation Antibacterial compounds having a (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide) motif
WO2005051318A2 (en) * 2003-11-24 2005-06-09 Viropharma Incorporated Compounds, compositions and methods for treatment and prophylaxis of hepatitis c viral infections and associated diseases
WO2016159092A1 (ja) * 2015-03-30 2016-10-06 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 エピルビシンの製造方法およびその新規な製造中間体

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA557568A (en) * 1958-05-20 J. Weiss Martin Substituted aminopyrrolecarboxylic acids and esters
CA547128A (en) * 1957-10-08 W. Waller Coy Substituted pyrrolecarboxamidopyrroles
FR86210E (enExample) * 1963-04-04 1966-03-23
FR141F (enExample) * 1963-07-26
BR6461040D0 (pt) * 1963-07-26 1973-08-02 Farmaceutici Italia Processo para preparar novos derivados de pirrol
BE666612A (enExample) * 1963-07-26 1965-11-03
DE1795539A1 (de) * 1963-07-26 1972-01-13 Farmaceutici Italia Verfahren zur Herstellung von neuen Pyrrolderivaten und ihren Salzen
NL130086C (enExample) * 1964-07-14 1970-06-15
SE468642B (sv) * 1985-07-16 1993-02-22 Erba Farmitalia Poly-4-aminopyrrol-2-karboxamidoderivat och foerfarande foer deras framstaellning och en farmaceutisk komposition
GB8612218D0 (en) * 1986-05-20 1986-06-25 Erba Farmitalia Site specific alkylating agents

Also Published As

Publication number Publication date
SE8603099L (sv) 1987-01-17
BE905109A (fr) 1987-01-15
GB8617293D0 (en) 1986-08-20
US4738980A (en) 1988-04-19
FI862960L (fi) 1987-01-17
AU6020386A (en) 1987-01-22
FI862960A0 (fi) 1986-07-16
GB2178037B (en) 1989-07-26
NO862861D0 (no) 1986-07-15
DK335886D0 (da) 1986-07-15
IL79401A (en) 1991-05-12
ATA188786A (de) 1988-03-15
FR2585019A1 (fr) 1987-01-23
NO169014B (no) 1992-01-20
DE3623853C2 (de) 1995-12-21
NO862861L (no) 1987-01-19
PH23459A (en) 1989-08-07
KR870001228A (ko) 1987-03-12
SE8603099D0 (sv) 1986-07-11
IE861874L (en) 1987-01-16
IL79401A0 (en) 1986-10-31
IE59275B1 (en) 1994-02-09
CN86104774A (zh) 1987-02-11
CN1026984C (zh) 1994-12-14
JPS6230755A (ja) 1987-02-09
IT1213103B (it) 1989-12-07
SU1535378A3 (ru) 1990-01-07
DE3623853A1 (de) 1987-01-29
GR861840B (en) 1986-11-18
CH671958A5 (enExample) 1989-10-13
DK335886A (da) 1987-01-17
IT8621124A0 (it) 1986-07-15
JPH0780842B2 (ja) 1995-08-30
NL8601838A (nl) 1987-02-16
FI82929B (fi) 1991-01-31
KR940003495B1 (ko) 1994-04-23
NZ216828A (en) 1989-11-28
PT82985B (pt) 1989-01-30
PT82985A (pt) 1986-08-01
CS541186A3 (en) 1992-09-16
AT386822B (de) 1988-10-25
NO169014C (no) 1992-04-29
ZA865262B (en) 1987-03-25
FI82929C (fi) 1991-05-10
SU1538893A3 (ru) 1990-01-23
AU584723B2 (en) 1989-06-01
FR2585019B1 (fr) 1989-07-13
GB2178037A (en) 1987-02-04
ES2000346A6 (es) 1988-02-16
CZ277823B6 (en) 1993-06-16
CN85103908A (zh) 1986-11-05
CA1247627A (en) 1988-12-28
HU198087B (en) 1989-07-28
SE468594B (sv) 1993-02-15
HUT41814A (en) 1987-05-28

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