GB201215857D0 - siRNA and their use in methods and compositions for the treatment and/or prevention of eye conditions - Google Patents
siRNA and their use in methods and compositions for the treatment and/or prevention of eye conditionsInfo
- Publication number
- GB201215857D0 GB201215857D0 GBGB1215857.2A GB201215857A GB201215857D0 GB 201215857 D0 GB201215857 D0 GB 201215857D0 GB 201215857 A GB201215857 A GB 201215857A GB 201215857 D0 GB201215857 D0 GB 201215857D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- sirna
- prevention
- compositions
- treatment
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 108020004459 Small interfering RNA Proteins 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/321—2'-O-R Modification
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Priority Applications (32)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1215857.2A GB201215857D0 (en) | 2012-09-05 | 2012-09-05 | siRNA and their use in methods and compositions for the treatment and/or prevention of eye conditions |
| SI201331090T SI2893019T1 (sl) | 2012-09-05 | 2013-09-04 | siRNA IN NJENA UPORABA V POSTOPKIH IN SESTAVKIH ZA ZDRAVLJENJE IN/ALI PREPREČEVANJU OBOLENJ OČI |
| MX2015002802A MX362854B (es) | 2012-09-05 | 2013-09-04 | Siarn y su uso en los metodos y composiciones para el tratamiento y/o prevencion de enfermedades de los ojos. |
| PE2015000282A PE20150619A1 (es) | 2012-09-05 | 2013-09-04 | Moleculas de siarn que interfieren con la expresion del receptor vaniloide-1 (trpv1) |
| EP13759707.6A EP2893019B1 (en) | 2012-09-05 | 2013-09-04 | Sirna and its use in methods and compositions for the treatment and/or prevention of eye conditions |
| US14/425,459 US9808479B2 (en) | 2012-09-05 | 2013-09-04 | SiRNA and their use in methods and compositions for the treatment and / or prevention of eye conditions |
| RS20180877A RS57620B1 (sr) | 2012-09-05 | 2013-09-04 | Sirnk i njena primena u metodama i kompozicijama za lečenje i/ili prevenciju očnih stanja |
| JP2015530372A JP2015529210A (ja) | 2012-09-05 | 2013-09-04 | 眼の状態を処置および／または防止するためのｓｉＲＮＡならびに方法および組成物におけるそれらの使用 |
| CN201380046215.0A CN104640988A (zh) | 2012-09-05 | 2013-09-04 | siRNA及其在用于治疗和/或预防眼部病症的方法和组合物中的应用 |
| PL13759707T PL2893019T3 (pl) | 2012-09-05 | 2013-09-04 | siRNA i jego zastosowanie w sposobach i kompozycjach do leczenia i/lub zapobiegania chorobom oczu |
| HRP20181079TT HRP20181079T1 (hr) | 2012-09-05 | 2013-09-04 | Sirnk i njena primjena u metodama i kompozicijama za liječenje i/ili prevenciju očnih stanja |
| DK13759707.6T DK2893019T3 (en) | 2012-09-05 | 2013-09-04 | SIRNA AND ITS USE IN METHODS AND COMPOSITIONS FOR TREATMENT AND / OR PREVENTION OF EYE DISEASES |
| IN2501DEN2015 IN2015DN02501A (enExample) | 2012-09-05 | 2013-09-04 | |
| HUE13759707A HUE040096T2 (hu) | 2012-09-05 | 2013-09-04 | siRNS és felhasználása eljárásokban és kompozíciókban szembajok kezelésére és/vagy megelõzésére |
| PCT/EP2013/068245 WO2014037377A1 (en) | 2012-09-05 | 2013-09-04 | Sirna and their use in methods and compositions for the treatment and/or prevention of eye conditions |
| LTEP13759707.6T LT2893019T (lt) | 2012-09-05 | 2013-09-04 | Sirnr ir jos panaudojimas būduose ir kompozicijose, skirtose akių ligų gydymui ir (arba) prevencijai |
| HK16100039.5A HK1212377B (en) | 2012-09-05 | 2013-09-04 | Sirna and its use in methods and compositions for the treatment and/or prevention of eye conditions |
| ES13759707.6T ES2685346T3 (es) | 2012-09-05 | 2013-09-04 | ARNip y su uso en métodos y composiciones para el tratamiento y/o la prevención de afecciones oculares |
| SG11201501386TA SG11201501386TA (en) | 2012-09-05 | 2013-09-04 | Sirna and their use in methods and compositions for the treatment and/or prevention of eye conditions |
| PT13759707T PT2893019T (pt) | 2012-09-05 | 2013-09-04 | Siarn e sua utilização em métodos e composições para o tratamento e/ou p~venção de afeções do olho |
| BR112015004469A BR112015004469B8 (pt) | 2012-09-05 | 2013-09-04 | Kit medicinal para administração de um sirna |
| RU2015112121A RU2663100C2 (ru) | 2012-09-05 | 2013-09-04 | Ми-рнк и их применение в способах и композициях для лечения и/или профилактики глазных состояний |
| CA2883040A CA2883040C (en) | 2012-09-05 | 2013-09-04 | Sirna and their use in methods and compositions for the treatment and/or prevention of eye conditions |
| AU2013311781A AU2013311781B2 (en) | 2012-09-05 | 2013-09-04 | SiRNA and their use in methods and compositions for the treatment and/or prevention of eye conditions |
| CN201810353730.8A CN108354944A (zh) | 2012-09-05 | 2013-09-04 | siRNA及其在用于治疗和/或预防眼部病症的方法和组合物中的应用 |
| KR1020157006165A KR102136539B1 (ko) | 2012-09-05 | 2013-09-04 | 눈 증상의 치료 및/또는 예방을 위한 방법 및 조성물에서 sirna 및 이들의 용도 |
| IL237389A IL237389B (en) | 2012-09-05 | 2015-02-24 | Short interfering RNA and its use in methods and preparations for the treatment and/or prevention of eye diseases |
| CL2015000537A CL2015000537A1 (es) | 2012-09-05 | 2015-03-04 | Siarn y su uso en los métodos y composiciones para el tratamiento y/o prevención de enfermedades de los ojos. |
| ZA2015/01494A ZA201501494B (en) | 2012-09-05 | 2015-03-04 | Sirna and their use in methods and compositions for the treatment and/or prevention of eye conditions |
| ECIEPI20159391A ECSP15009391A (es) | 2012-09-05 | 2015-03-12 | siARN Y SU USO EN LOS MÉTODOS Y COMPOSICIONES PARA EL TRATAMIENTO Y/O PREVENCIÓN DE ENFERMEDADES DE LOS OJOS |
| JP2018090693A JP6742362B2 (ja) | 2012-09-05 | 2018-05-09 | 眼の状態を処置および／または防止するためのｓｉＲＮＡならびに方法および組成物におけるそれらの使用 |
| CY181100845T CY1121000T1 (el) | 2012-09-05 | 2018-08-10 | Sirna και χρηση αυτου σε μεθοδους και συνθεσεις για την θεραπεια ή/και προληψη οφθαλμικων καταστασεων |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1215857.2A GB201215857D0 (en) | 2012-09-05 | 2012-09-05 | siRNA and their use in methods and compositions for the treatment and/or prevention of eye conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB201215857D0 true GB201215857D0 (en) | 2012-10-24 |
Family
ID=47136985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB1215857.2A Ceased GB201215857D0 (en) | 2012-09-05 | 2012-09-05 | siRNA and their use in methods and compositions for the treatment and/or prevention of eye conditions |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US9808479B2 (enExample) |
| EP (1) | EP2893019B1 (enExample) |
| JP (2) | JP2015529210A (enExample) |
| KR (1) | KR102136539B1 (enExample) |
| CN (2) | CN108354944A (enExample) |
| AU (1) | AU2013311781B2 (enExample) |
| BR (1) | BR112015004469B8 (enExample) |
| CA (1) | CA2883040C (enExample) |
| CL (1) | CL2015000537A1 (enExample) |
| CY (1) | CY1121000T1 (enExample) |
| DK (1) | DK2893019T3 (enExample) |
| EC (1) | ECSP15009391A (enExample) |
| ES (1) | ES2685346T3 (enExample) |
| GB (1) | GB201215857D0 (enExample) |
| HR (1) | HRP20181079T1 (enExample) |
| HU (1) | HUE040096T2 (enExample) |
| IL (1) | IL237389B (enExample) |
| IN (1) | IN2015DN02501A (enExample) |
| LT (1) | LT2893019T (enExample) |
| MX (1) | MX362854B (enExample) |
| PE (1) | PE20150619A1 (enExample) |
| PL (1) | PL2893019T3 (enExample) |
| PT (1) | PT2893019T (enExample) |
| RS (1) | RS57620B1 (enExample) |
| RU (1) | RU2663100C2 (enExample) |
| SG (1) | SG11201501386TA (enExample) |
| SI (1) | SI2893019T1 (enExample) |
| WO (1) | WO2014037377A1 (enExample) |
| ZA (1) | ZA201501494B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2726613T1 (sl) | 2011-06-30 | 2018-10-30 | Arrowhead Pharmaceuticals, Inc. | Sestavki in postopki za zaviranje izražanja gena virusa hepatitisa B |
| CN108271387B (zh) | 2015-08-07 | 2023-06-27 | 箭头药业股份有限公司 | 乙型肝炎病毒感染的RNAi疗法 |
| JOP20170161A1 (ar) | 2016-08-04 | 2019-01-30 | Arrowhead Pharmaceuticals Inc | عوامل RNAi للعدوى بفيروس التهاب الكبد ب |
| JP6994061B2 (ja) | 2019-02-15 | 2022-01-14 | ノバルティス アーゲー | ４－（７－ヒドロキシ－２－イソプロピル－４－オキソ－４ｈ－キナゾリン－３－イル）－ベンゾニトリルの製剤 |
| CN113453686B (zh) | 2019-02-15 | 2025-04-15 | 博士伦爱尔兰有限公司 | 治疗眼表痛的方法 |
| ES3031607T3 (en) * | 2019-10-04 | 2025-07-09 | Senju Pharma Co | Pharmaceutical composition containing heterocyclidene acetamide derivative for use in treating dry eye |
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| WO2005117938A2 (en) | 2004-04-13 | 2005-12-15 | Regents Of The University Of Minnesota | Methods of treating ocular conditions |
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| TW200927192A (en) * | 2007-11-19 | 2009-07-01 | Alcon Res Ltd | Use of TRPV1 receptor antagonists for treating dry eye and ocular pain |
| CN201337650Y (zh) * | 2009-01-06 | 2009-11-04 | 河北科技大学 | 一次性药用单剂量液体容器 |
| EP2390327A1 (en) * | 2010-05-27 | 2011-11-30 | Sylentis S.A. | siRNA and their use in methods and compositions for the treatment and/or prevention of eye conditions |
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