MX362854B - Siarn y su uso en los metodos y composiciones para el tratamiento y/o prevencion de enfermedades de los ojos. - Google Patents

Siarn y su uso en los metodos y composiciones para el tratamiento y/o prevencion de enfermedades de los ojos.

Info

Publication number
MX362854B
MX362854B MX2015002802A MX2015002802A MX362854B MX 362854 B MX362854 B MX 362854B MX 2015002802 A MX2015002802 A MX 2015002802A MX 2015002802 A MX2015002802 A MX 2015002802A MX 362854 B MX362854 B MX 362854B
Authority
MX
Mexico
Prior art keywords
prevention
compositions
treatment
methods
sirna
Prior art date
Application number
MX2015002802A
Other languages
English (en)
Other versions
MX2015002802A (es
Inventor
Isabel Jimenez Anton Ana
Gonzalez Fajardo Victoria
Ruz Palomar Veronica
Original Assignee
Sylentis Sau
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sylentis Sau filed Critical Sylentis Sau
Publication of MX2015002802A publication Critical patent/MX2015002802A/es
Publication of MX362854B publication Critical patent/MX362854B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/321—2'-O-R Modification

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a métodos y composiciones para el tratamiento y/o prevención de afecciones oculares relacionadas con altos niveles de expresión y/o actividad del receptor vaniloide-1 (TRPV).
MX2015002802A 2012-09-05 2013-09-04 Siarn y su uso en los metodos y composiciones para el tratamiento y/o prevencion de enfermedades de los ojos. MX362854B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1215857.2A GB201215857D0 (en) 2012-09-05 2012-09-05 siRNA and their use in methods and compositions for the treatment and/or prevention of eye conditions
PCT/EP2013/068245 WO2014037377A1 (en) 2012-09-05 2013-09-04 Sirna and their use in methods and compositions for the treatment and/or prevention of eye conditions

Publications (2)

Publication Number Publication Date
MX2015002802A MX2015002802A (es) 2015-05-15
MX362854B true MX362854B (es) 2019-02-20

Family

ID=47136985

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015002802A MX362854B (es) 2012-09-05 2013-09-04 Siarn y su uso en los metodos y composiciones para el tratamiento y/o prevencion de enfermedades de los ojos.

Country Status (30)

Country Link
US (1) US9808479B2 (es)
EP (1) EP2893019B1 (es)
JP (2) JP2015529210A (es)
KR (1) KR102136539B1 (es)
CN (2) CN104640988A (es)
AU (1) AU2013311781B2 (es)
BR (1) BR112015004469B8 (es)
CA (1) CA2883040C (es)
CL (1) CL2015000537A1 (es)
CY (1) CY1121000T1 (es)
DK (1) DK2893019T3 (es)
EC (1) ECSP15009391A (es)
ES (1) ES2685346T3 (es)
GB (1) GB201215857D0 (es)
HK (1) HK1212377A1 (es)
HR (1) HRP20181079T1 (es)
HU (1) HUE040096T2 (es)
IL (1) IL237389B (es)
IN (1) IN2015DN02501A (es)
LT (1) LT2893019T (es)
MX (1) MX362854B (es)
PE (1) PE20150619A1 (es)
PL (1) PL2893019T3 (es)
PT (1) PT2893019T (es)
RS (1) RS57620B1 (es)
RU (1) RU2663100C2 (es)
SG (1) SG11201501386TA (es)
SI (1) SI2893019T1 (es)
WO (1) WO2014037377A1 (es)
ZA (1) ZA201501494B (es)

Families Citing this family (5)

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PT2726613T (pt) 2011-06-30 2018-10-26 Arrowhead Pharmaceuticals Inc Composições e métodos para inibição da expressão de genes do vírus da hepatite b
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JOP20170161A1 (ar) 2016-08-04 2019-01-30 Arrowhead Pharmaceuticals Inc عوامل RNAi للعدوى بفيروس التهاب الكبد ب
AU2020222348B2 (en) 2019-02-15 2023-03-16 Bausch + Lomb Ireland Limited Methods for treating ocular surface pain
JP6994061B2 (ja) 2019-02-15 2022-01-14 ノバルティス アーゲー ４－（７－ヒドロキシ－２－イソプロピル－４－オキソ－４ｈ－キナゾリン－３－イル）－ベンゾニトリルの製剤

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Also Published As

Publication number Publication date
GB201215857D0 (en) 2012-10-24
US9808479B2 (en) 2017-11-07
CY1121000T1 (el) 2019-12-11
KR102136539B1 (ko) 2020-07-23
KR20150047513A (ko) 2015-05-04
LT2893019T (lt) 2018-08-10
MX2015002802A (es) 2015-05-15
CA2883040A1 (en) 2014-03-13
CN104640988A (zh) 2015-05-20
ES2685346T3 (es) 2018-10-08
PL2893019T3 (pl) 2018-12-31
EP2893019B1 (en) 2018-05-30
DK2893019T3 (en) 2018-09-03
AU2013311781B2 (en) 2018-10-18
JP2015529210A (ja) 2015-10-05
AU2013311781A1 (en) 2015-03-12
IN2015DN02501A (es) 2015-09-11
PT2893019T (pt) 2018-10-19
ZA201501494B (en) 2016-01-27
PE20150619A1 (es) 2015-05-11
IL237389A0 (en) 2015-04-30
BR112015004469B8 (pt) 2022-12-06
RU2663100C2 (ru) 2018-08-01
JP2018138596A (ja) 2018-09-06
HUE040096T2 (hu) 2019-02-28
BR112015004469A2 (pt) 2017-08-08
RU2015112121A (ru) 2016-10-27
RS57620B1 (sr) 2018-11-30
CN108354944A (zh) 2018-08-03
CA2883040C (en) 2023-01-17
CL2015000537A1 (es) 2015-07-10
IL237389B (en) 2019-01-31
SI2893019T1 (sl) 2018-09-28
JP6742362B2 (ja) 2020-08-19
HRP20181079T1 (hr) 2018-09-07
US20150224131A1 (en) 2015-08-13
HK1212377A1 (en) 2016-06-10
SG11201501386TA (en) 2015-03-30
EP2893019A1 (en) 2015-07-15
WO2014037377A1 (en) 2014-03-13
ECSP15009391A (es) 2015-12-31
BR112015004469B1 (pt) 2022-11-16

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