IN2015DN02501A - - Google Patents

Info

Publication number
IN2015DN02501A
IN2015DN02501A IN2501DEN2015A IN2015DN02501A IN 2015DN02501 A IN2015DN02501 A IN 2015DN02501A IN 2501DEN2015 A IN2501DEN2015 A IN 2501DEN2015A IN 2015DN02501 A IN2015DN02501 A IN 2015DN02501A
Authority
IN
India
Prior art keywords
trpv
vanilloid
receptor
prevention
expression
Prior art date
Application number
Inventor
Anton Ana Isabel Jimenez
Fajardo Victoria Gonzalez
Palomar Veronica Ruz
Original Assignee
Sylentis Sau
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sylentis Sau filed Critical Sylentis Sau
Publication of IN2015DN02501A publication Critical patent/IN2015DN02501A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/321—2'-O-R Modification

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to methods and compositions for the treatment and/or prevention of eye conditions related to high levels of expression and/or activity of the vanilloid- 1 receptor (TRPV).
IN2501DEN2015 2012-09-05 2013-09-04 IN2015DN02501A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1215857.2A GB201215857D0 (en) 2012-09-05 2012-09-05 siRNA and their use in methods and compositions for the treatment and/or prevention of eye conditions
PCT/EP2013/068245 WO2014037377A1 (en) 2012-09-05 2013-09-04 Sirna and their use in methods and compositions for the treatment and/or prevention of eye conditions

Publications (1)

Publication Number Publication Date
IN2015DN02501A true IN2015DN02501A (en) 2015-09-11

Family

ID=47136985

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2501DEN2015 IN2015DN02501A (en) 2012-09-05 2013-09-04

Country Status (30)

Country Link
US (1) US9808479B2 (en)
EP (1) EP2893019B1 (en)
JP (2) JP2015529210A (en)
KR (1) KR102136539B1 (en)
CN (2) CN108354944A (en)
AU (1) AU2013311781B2 (en)
BR (1) BR112015004469B8 (en)
CA (1) CA2883040C (en)
CL (1) CL2015000537A1 (en)
CY (1) CY1121000T1 (en)
DK (1) DK2893019T3 (en)
EC (1) ECSP15009391A (en)
ES (1) ES2685346T3 (en)
GB (1) GB201215857D0 (en)
HK (1) HK1212377A1 (en)
HR (1) HRP20181079T1 (en)
HU (1) HUE040096T2 (en)
IL (1) IL237389B (en)
IN (1) IN2015DN02501A (en)
LT (1) LT2893019T (en)
MX (1) MX362854B (en)
PE (1) PE20150619A1 (en)
PL (1) PL2893019T3 (en)
PT (1) PT2893019T (en)
RS (1) RS57620B1 (en)
RU (1) RU2663100C2 (en)
SG (1) SG11201501386TA (en)
SI (1) SI2893019T1 (en)
WO (1) WO2014037377A1 (en)
ZA (1) ZA201501494B (en)

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WO2013003520A1 (en) 2011-06-30 2013-01-03 Arrowhead Research Corporation Compositions and methods for inhibiting gene expression of hepatitis b virus
EP3332007A4 (en) 2015-08-07 2019-07-17 Arrowhead Pharmaceuticals, Inc. Rnai therapy for hepatitis b virus infection
JOP20170161A1 (en) 2016-08-04 2019-01-30 Arrowhead Pharmaceuticals Inc RNAi Agents for Hepatitis B Virus Infection
KR20210129677A (en) 2019-02-15 2021-10-28 노파르티스 아게 How to treat ocular surface pain
JP6994061B2 (en) 2019-02-15 2022-01-14 ノバルティス アーゲー Preparation of 4- (7-hydroxy-2-isopropyl-4-oxo-4H-quinazoline-3-yl) -benzonitrile
EP4043014A4 (en) * 2019-10-04 2023-10-11 Senju Pharmaceutical Co., Ltd. Pharmaceutical drug containing heterocyclidene acetamide derivative

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Also Published As

Publication number Publication date
HK1212377A1 (en) 2016-06-10
RU2663100C2 (en) 2018-08-01
CA2883040C (en) 2023-01-17
JP2015529210A (en) 2015-10-05
SG11201501386TA (en) 2015-03-30
AU2013311781B2 (en) 2018-10-18
CA2883040A1 (en) 2014-03-13
IL237389A0 (en) 2015-04-30
ECSP15009391A (en) 2015-12-31
US9808479B2 (en) 2017-11-07
CY1121000T1 (en) 2019-12-11
PE20150619A1 (en) 2015-05-11
CN108354944A (en) 2018-08-03
LT2893019T (en) 2018-08-10
MX2015002802A (en) 2015-05-15
BR112015004469A2 (en) 2017-08-08
SI2893019T1 (en) 2018-09-28
WO2014037377A1 (en) 2014-03-13
AU2013311781A1 (en) 2015-03-12
BR112015004469B8 (en) 2022-12-06
US20150224131A1 (en) 2015-08-13
BR112015004469B1 (en) 2022-11-16
RS57620B1 (en) 2018-11-30
IL237389B (en) 2019-01-31
JP6742362B2 (en) 2020-08-19
EP2893019A1 (en) 2015-07-15
HUE040096T2 (en) 2019-02-28
ES2685346T3 (en) 2018-10-08
GB201215857D0 (en) 2012-10-24
KR20150047513A (en) 2015-05-04
DK2893019T3 (en) 2018-09-03
CL2015000537A1 (en) 2015-07-10
CN104640988A (en) 2015-05-20
PT2893019T (en) 2018-10-19
ZA201501494B (en) 2016-01-27
PL2893019T3 (en) 2018-12-31
JP2018138596A (en) 2018-09-06
RU2015112121A (en) 2016-10-27
KR102136539B1 (en) 2020-07-23
MX362854B (en) 2019-02-20
EP2893019B1 (en) 2018-05-30
HRP20181079T1 (en) 2018-09-07

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