GB1377265A - Phenylimino-3-aza 1-thia-cycloalkanes their preparation and their medicinal use - Google Patents
Phenylimino-3-aza 1-thia-cycloalkanes their preparation and their medicinal useInfo
- Publication number
- GB1377265A GB1377265A GB4255272A GB4255272A GB1377265A GB 1377265 A GB1377265 A GB 1377265A GB 4255272 A GB4255272 A GB 4255272A GB 4255272 A GB4255272 A GB 4255272A GB 1377265 A GB1377265 A GB 1377265A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- optionally substituted
- alkoxy
- alkyl
- alkenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 12
- -1 Phenylimino Chemical group 0.000 abstract 9
- 125000003342 alkenyl group Chemical group 0.000 abstract 6
- 125000003545 alkoxy group Chemical group 0.000 abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000004423 acyloxy group Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 150000002825 nitriles Chemical class 0.000 abstract 3
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 3
- 125000000304 alkynyl group Chemical group 0.000 abstract 2
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 2
- WHHUGOCPYAPVEL-UHFFFAOYSA-N 3-methyl-n-(4-nitrophenyl)-1,3-thiazolidin-2-imine Chemical compound CN1CCSC1=NC1=CC=C([N+]([O-])=O)C=C1 WHHUGOCPYAPVEL-UHFFFAOYSA-N 0.000 abstract 1
- WZKSXHQDXQKIQJ-UHFFFAOYSA-N F[C](F)F Chemical compound F[C](F)F WZKSXHQDXQKIQJ-UHFFFAOYSA-N 0.000 abstract 1
- 241000534944 Thia Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000005083 alkoxyalkoxy group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 230000000507 anthelmentic effect Effects 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001485 cycloalkadienyl group Chemical group 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 1
- 125000005112 cycloalkylalkoxy group Chemical group 0.000 abstract 1
- 125000003754 ethoxycarbonyl group Chemical group C(=O)(OCC)* 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000000636 p-nitrophenyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1*)[N+]([O-])=O 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002071 phenylalkoxy group Chemical group 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000010561 standard procedure Methods 0.000 abstract 1
- 125000003718 tetrahydrofuranyl group Chemical group 0.000 abstract 1
- 125000001412 tetrahydropyranyl group Chemical group 0.000 abstract 1
- 150000003585 thioureas Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/18—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C335/20—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2145807A DE2145807A1 (de) | 1971-09-14 | 1971-09-14 | 2-(aminophenylimino)-3-aza-1-thiacycloalkane, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1377265A true GB1377265A (en) | 1974-12-11 |
Family
ID=5819465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4255272A Expired GB1377265A (en) | 1971-09-14 | 1972-09-13 | Phenylimino-3-aza 1-thia-cycloalkanes their preparation and their medicinal use |
Country Status (22)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6353006B1 (en) | 1999-01-14 | 2002-03-05 | Bayer Corporation | Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU167761B (enrdf_load_stackoverflow) * | 1973-07-12 | 1975-12-25 | ||
| US4140784A (en) * | 1976-09-17 | 1979-02-20 | Ciba-Geigy Corporation | Novel thiazolidines |
| IL52927A (en) * | 1976-09-17 | 1980-01-31 | Ciba Geigy Ag | 2-(n-methylcarbamoyloxyphenyl imino)-4-thiazoline derivatives their production and their use as pesticides |
| DE2758005A1 (de) | 1977-12-24 | 1979-06-28 | Bayer Ag | Phosphonylureidobenzol-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3632042A1 (de) * | 1986-03-08 | 1987-09-10 | Bayer Ag | Diarylsulfidderivate |
| CN1247553C (zh) | 1999-09-14 | 2006-03-29 | 盐野义制药株式会社 | 2－亚氨基－1,3－噻嗪衍生物 |
| DE102008030764A1 (de) * | 2008-06-28 | 2009-12-31 | Bayer Animal Health Gmbh | Kombination von Amidin-Derivaten mit cyclischen Depsipeptiden |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US327708A (en) * | 1885-10-06 | Wet-ore concentrator | ||
| US2877232A (en) * | 1957-12-31 | 1959-03-10 | Ciba Pharm Prod Inc | 2-(4-isopentyloxyphenyl)-imino, 3 (4-isopentyloxyphenyl)-thiazolidine and therapeutically useful salts |
| US3297708A (en) * | 1965-10-06 | 1967-01-10 | American Cyanamid Co | Method of preparing thiazolidines |
| FR1516854A (fr) * | 1966-12-20 | 1968-02-05 | Aquitaine Petrole | Procédé pour la production d'imino-thiazolidines |
-
0
- BE BE788743D patent/BE788743A/xx unknown
-
1971
- 1971-09-14 DE DE2145807A patent/DE2145807A1/de active Pending
-
1972
- 1972-08-30 RO RO80697A patent/RO84248B/ro unknown
- 1972-08-30 RO RO7280698A patent/RO68389A/ro unknown
- 1972-08-30 RO RO80696A patent/RO84247B/ro unknown
- 1972-08-30 RO RO7280695A patent/RO68372A/ro unknown
- 1972-09-12 IL IL40338A patent/IL40338A/en unknown
- 1972-09-12 DD DD173372*A patent/DD105990A5/xx unknown
- 1972-09-12 SU SU1827229A patent/SU505363A3/ru active
- 1972-09-12 SU SU1827231A patent/SU455544A3/ru active
- 1972-09-12 EG EG371/72A patent/EG11037A/xx active
- 1972-09-12 CH CH1338372A patent/CH569724A5/xx not_active IP Right Cessation
- 1972-09-12 DD DD165616A patent/DD103898A5/xx unknown
- 1972-09-12 SU SU1827228A patent/SU556728A3/ru active
- 1972-09-12 CH CH1020475A patent/CH587258A5/xx not_active IP Right Cessation
- 1972-09-13 PL PL1972182585A patent/PL93588B1/pl unknown
- 1972-09-13 IE IE1249/72A patent/IE36698B1/xx unknown
- 1972-09-13 GB GB4255272A patent/GB1377265A/en not_active Expired
- 1972-09-13 AU AU46604/72A patent/AU464649B2/en not_active Expired
- 1972-09-13 PL PL1972182587A patent/PL93690B1/pl unknown
- 1972-09-13 NL NL7212419A patent/NL7212419A/xx not_active Application Discontinuation
- 1972-09-13 PL PL1972182586A patent/PL93669B1/pl unknown
- 1972-09-13 HU HU72BA2802A patent/HU167410B/hu unknown
- 1972-09-13 ES ES406622A patent/ES406622A1/es not_active Expired
- 1972-09-13 JP JP47091344A patent/JPS4836169A/ja active Pending
- 1972-09-13 JP JP47091343A patent/JPS4836168A/ja active Pending
- 1972-09-13 PL PL1972157720A patent/PL89701B1/pl unknown
- 1972-09-13 ZA ZA726271A patent/ZA726271B/xx unknown
- 1972-09-13 CA CA151,607A patent/CA1007638A/en not_active Expired
- 1972-09-13 SE SE7211813A patent/SE412756B/xx unknown
- 1972-09-14 AT AT789772A patent/AT322548B/de not_active IP Right Cessation
- 1972-09-14 US US289092A patent/US3860590A/en not_active Expired - Lifetime
- 1972-09-14 FR FR7232634A patent/FR2154512B1/fr not_active Expired
-
1975
- 1975-04-01 ES ES436200A patent/ES436200A1/es not_active Expired
- 1975-04-01 ES ES436201A patent/ES436201A1/es not_active Expired
- 1975-04-01 ES ES436202A patent/ES436202A1/es not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6353006B1 (en) | 1999-01-14 | 2002-03-05 | Bayer Corporation | Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |