GB1370066A - N,n1-bis-2-3-substituted-4-hydroxyphenyl-ethyl or 2-hydroxyethyl- polymethylenediamines - Google Patents

N,n1-bis-2-3-substituted-4-hydroxyphenyl-ethyl or 2-hydroxyethyl- polymethylenediamines

Info

Publication number
GB1370066A
GB1370066A GB2526972A GB2526972A GB1370066A GB 1370066 A GB1370066 A GB 1370066A GB 2526972 A GB2526972 A GB 2526972A GB 2526972 A GB2526972 A GB 2526972A GB 1370066 A GB1370066 A GB 1370066A
Authority
GB
United Kingdom
Prior art keywords
nhso
hydroxyphenyl
hydroxyethyl
bis
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2526972A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
SmithKline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Corp filed Critical SmithKline Corp
Publication of GB1370066A publication Critical patent/GB1370066A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/40—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1370066 N,N<SP>1</SP> - Bis - [2 - (3 - substituted - 4 - hydroxyphenyl-ethyl or - 2 - hydroxyethyl] - alkylene diamines and intermediates therefor SMITHKLINE CORP 30 May 1972 [1 June 1971] 25269/72 Heading C2C Novel compounds (I) and (IV) (including salts thereof) where n is 4 to 8, Z is H or OH, Y is NH 2 , NHCHO, NHCOMe, NHCONH 2 ; NHSO 2 R, NHCO 2 R, NHCONHR, NHSO 2 NH 2 , NHSO 2 NMe 2 , CH 2 OH, CH 2 NH 2 , CH 2 NHSO 2 R, CH 2 NHCONH 2 or CH 2 SO 2 R, and R is C 1 to C 5 alkyl, are made by standard methods from compounds (II) to (VII). Pharmaceutical preparations having bronchodilatory action contain (I) as active ingredient. Standard forms of administration can be utilized.
GB2526972A 1971-06-01 1972-05-30 N,n1-bis-2-3-substituted-4-hydroxyphenyl-ethyl or 2-hydroxyethyl- polymethylenediamines Expired GB1370066A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14891271A 1971-06-01 1971-06-01

Publications (1)

Publication Number Publication Date
GB1370066A true GB1370066A (en) 1974-10-09

Family

ID=22527996

Family Applications (3)

Application Number Title Priority Date Filing Date
GB2526972A Expired GB1370066A (en) 1971-06-01 1972-05-30 N,n1-bis-2-3-substituted-4-hydroxyphenyl-ethyl or 2-hydroxyethyl- polymethylenediamines
GB1482574A Expired GB1370068A (en) 1971-06-01 1972-05-30 N,n1-dibenzyl -n,n1-bis-2-3,4,-disubstituted-phenyl-2-oxoethyl- polymethylenediamines
GB1482474A Expired GB1370067A (en) 1971-06-01 1972-05-30 N,n1-dibenzyl-n,n1-bis-2-3,4-disubstituted phenyl ethyl- poly methylenediamines

Family Applications After (2)

Application Number Title Priority Date Filing Date
GB1482574A Expired GB1370068A (en) 1971-06-01 1972-05-30 N,n1-dibenzyl -n,n1-bis-2-3,4,-disubstituted-phenyl-2-oxoethyl- polymethylenediamines
GB1482474A Expired GB1370067A (en) 1971-06-01 1972-05-30 N,n1-dibenzyl-n,n1-bis-2-3,4-disubstituted phenyl ethyl- poly methylenediamines

Country Status (8)

Country Link
JP (1) JPS5614656B1 (en)
AU (1) AU474656B2 (en)
BE (1) BE784105A (en)
CA (1) CA1044699A (en)
DE (1) DE2227022C2 (en)
FR (1) FR2140149B1 (en)
GB (3) GB1370066A (en)
ZA (1) ZA723611B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1386029A (en) * 1972-03-20 1975-03-05 Smithkline Corp Alpha-benzylamino-4-benzyloxy-3-alkylsulphonylmethyl phenones
EP0142283B1 (en) * 1983-10-25 1991-01-30 FISONS plc Phenylethylamines, process for their preparation and compositions containing them
JPH01163553U (en) * 1988-04-30 1989-11-15
JPH04106659U (en) * 1991-02-20 1992-09-14 本田技研工業株式会社 electrostatic coating equipment
US6713651B1 (en) 1999-06-07 2004-03-30 Theravance, Inc. β2-adrenergic receptor agonists
US6362371B1 (en) 1998-06-08 2002-03-26 Advanced Medicine, Inc. β2- adrenergic receptor agonists
FR2788768B1 (en) 1999-01-21 2001-02-16 Oreal NEW CATIONIC 2-ACYLAMINOPHENOLS, THEIR USE AS COUPLER FOR OXIDATION DYEING, COMPOSITIONS COMPRISING THEM, AND DYEING METHODS
US6683115B2 (en) 1999-06-02 2004-01-27 Theravance, Inc. β2-adrenergic receptor agonists
UA73965C2 (en) 1999-12-08 2005-10-17 Theravance Inc b2 ADRENERGIC RECEPTOR ANTAGONISTS

Also Published As

Publication number Publication date
FR2140149A1 (en) 1973-01-12
GB1370068A (en) 1974-10-09
GB1370067A (en) 1974-10-09
CA1044699A (en) 1978-12-19
AU4296572A (en) 1973-12-06
AU474656B2 (en) 1976-07-29
DE2227022A1 (en) 1972-12-14
ZA723611B (en) 1973-03-28
FR2140149B1 (en) 1976-03-05
JPS5614656B1 (en) 1981-04-06
DE2227022C2 (en) 1983-01-13
BE784105A (en) 1972-11-29

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee