GB1268658A - Acid phthalates of cellulose ethers and their preparation and uses - Google Patents
Acid phthalates of cellulose ethers and their preparation and usesInfo
- Publication number
- GB1268658A GB1268658A GB43552/69A GB4355269A GB1268658A GB 1268658 A GB1268658 A GB 1268658A GB 43552/69 A GB43552/69 A GB 43552/69A GB 4355269 A GB4355269 A GB 4355269A GB 1268658 A GB1268658 A GB 1268658A
- Authority
- GB
- United Kingdom
- Prior art keywords
- sept
- silica
- cellulose
- preparation
- coating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 229920003086 cellulose ether Polymers 0.000 title abstract 2
- 125000005498 phthalate group Chemical class 0.000 title 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 4
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 239000001913 cellulose Substances 0.000 abstract 2
- 229920002678 cellulose Polymers 0.000 abstract 2
- 239000008199 coating composition Substances 0.000 abstract 2
- 239000012530 fluid Substances 0.000 abstract 2
- -1 hydroxypropyl Chemical group 0.000 abstract 2
- 239000000377 silicon dioxide Substances 0.000 abstract 2
- FJLUATLTXUNBOT-UHFFFAOYSA-N 1-Hexadecylamine Chemical compound CCCCCCCCCCCCCCCCN FJLUATLTXUNBOT-UHFFFAOYSA-N 0.000 abstract 1
- KMZHZAAOEWVPSE-UHFFFAOYSA-N 2,3-dihydroxypropyl acetate Chemical compound CC(=O)OCC(O)CO KMZHZAAOEWVPSE-UHFFFAOYSA-N 0.000 abstract 1
- 239000005995 Aluminium silicate Substances 0.000 abstract 1
- 229910010413 TiO 2 Inorganic materials 0.000 abstract 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 abstract 1
- 235000012211 aluminium silicate Nutrition 0.000 abstract 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 abstract 1
- 239000004327 boric acid Substances 0.000 abstract 1
- 229910000019 calcium carbonate Inorganic materials 0.000 abstract 1
- 239000001506 calcium phosphate Substances 0.000 abstract 1
- 229910000389 calcium phosphate Inorganic materials 0.000 abstract 1
- 235000011010 calcium phosphates Nutrition 0.000 abstract 1
- LQZZUXJYWNFBMV-UHFFFAOYSA-N dodecan-1-ol Chemical compound CCCCCCCCCCCCO LQZZUXJYWNFBMV-UHFFFAOYSA-N 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000002702 enteric coating Substances 0.000 abstract 1
- 238000009505 enteric coating Methods 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 230000000968 intestinal effect Effects 0.000 abstract 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920001206 natural gum Polymers 0.000 abstract 1
- 229920005615 natural polymer Polymers 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- XNGIFLGASWRNHJ-UHFFFAOYSA-L phthalate(2-) Chemical compound [O-]C(=O)C1=CC=CC=C1C([O-])=O XNGIFLGASWRNHJ-UHFFFAOYSA-L 0.000 abstract 1
- 239000004014 plasticizer Substances 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- 229920001059 synthetic polymer Polymers 0.000 abstract 1
- 239000000454 talc Substances 0.000 abstract 1
- 229910052623 talc Inorganic materials 0.000 abstract 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B11/00—Preparation of cellulose ethers
- C08B11/02—Alkyl or cycloalkyl ethers
- C08B11/04—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals
- C08B11/08—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals with hydroxylated hydrocarbon radicals; Esters, ethers, or acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B11/00—Preparation of cellulose ethers
- C08B11/193—Mixed ethers, i.e. ethers with two or more different etherifying groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B13/00—Preparation of cellulose ether-esters
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B3/00—Preparation of cellulose esters of organic acids
- C08B3/12—Preparation of cellulose esters of organic acids of polybasic organic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6594968 | 1968-09-12 | ||
| JP6595068 | 1968-09-12 | ||
| JP1815269 | 1969-03-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1268658A true GB1268658A (en) | 1972-03-29 |
Family
ID=27282106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB43552/69A Expired GB1268658A (en) | 1968-09-12 | 1969-09-03 | Acid phthalates of cellulose ethers and their preparation and uses |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US3629237A (https=) |
| CH (1) | CH523073A (https=) |
| FR (1) | FR2020529A1 (https=) |
| GB (1) | GB1268658A (https=) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2132887A (en) * | 1982-11-15 | 1984-07-18 | Procter & Gamble | Enteric-coated anti-inflammatory compositions |
| EP0111103A3 (en) * | 1982-11-08 | 1985-06-19 | Fmc Corporation | Enteric coating for pharmaceutical dosage forms |
| GB2285989A (en) * | 1994-01-28 | 1995-08-02 | Merck Frosst Canada Inc | Aqueous formulations for enteric coatings |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2140996C3 (de) * | 1971-03-19 | 1980-06-19 | Shinetsu Chemical Co., Tokio | Verwendung eines Celluloseether esters in Überzugsmitteln fur darmwirksame pharmazeutische Produkte |
| US3870702A (en) * | 1971-03-19 | 1975-03-11 | Shinetsu Chemical Co | Cellulose ether compositions useful as enteric coatings |
| US3789117A (en) * | 1971-07-19 | 1974-01-29 | Freunt Ind Co Ltd | Process for the preparation of enteric medicaments |
| JPS5518694B2 (https=) * | 1973-04-02 | 1980-05-21 | ||
| US4226981A (en) * | 1977-09-28 | 1980-10-07 | Shin-Etsu Chemical Co., Ltd. | Ether-ester derivatives of cellulose and their applications |
| JPS5535031A (en) * | 1978-09-04 | 1980-03-11 | Shin Etsu Chem Co Ltd | Enteric coating composition |
| SE457505B (sv) * | 1984-01-10 | 1989-01-09 | Lejus Medical Ab | Laminatbelagd oral farmaceutisk komposition och foerfarande foer dess framstaellning |
| US5723151A (en) * | 1995-11-06 | 1998-03-03 | Eastman Chemical Company | Cellulose acetate phthalate enteric coating compositions |
| KR100387126B1 (ko) * | 2001-04-19 | 2003-06-12 | 삼성정밀화학 주식회사 | 히드록시프로필메틸 셀룰로오스 프탈레이트의 분리정제방법 |
| KR100442112B1 (ko) * | 2001-10-08 | 2004-07-30 | 삼성정밀화학 주식회사 | 히드록시프로필메틸 셀룰로오스 프탈레이트의 제조 방법 |
| SE0103424D0 (sv) * | 2001-10-15 | 2001-10-15 | Astrazeneca Ab | Pharmaceutical formulation |
| JP6166372B2 (ja) * | 2012-08-24 | 2017-07-19 | ダウ グローバル テクノロジーズ エルエルシー | アルカリ金属カルボン酸塩および脂肪族カルボン酸の存在下でエステル化セルロースエーテルを調製するためのプロセス |
| CN104231091B (zh) * | 2014-09-29 | 2016-06-22 | 泸州北方化学工业有限公司 | 羟丙基甲基纤维素邻苯二甲酸酯的制备方法 |
| MX355025B (es) | 2014-10-31 | 2018-04-02 | Dow Global Technologies Llc | Proceso eficiente para preparar ester de eter de celulosa. |
| CN107074979B (zh) | 2014-10-31 | 2019-07-19 | 陶氏环球技术有限责任公司 | 用于产生乙酸纤维素醚丁二酸酯的方法 |
| JP2017533324A (ja) * | 2014-10-31 | 2017-11-09 | ダウ グローバル テクノロジーズ エルエルシー | セルロースエーテルのエステルを調製するための方法 |
| KR20170076965A (ko) | 2015-12-24 | 2017-07-05 | 롯데정밀화학 주식회사 | 히드록시프로필메틸 셀룰로오스 프탈레이트 입자 및 그 제조방법 |
| BR112018074763A2 (pt) | 2016-06-23 | 2019-03-06 | Dow Global Technologies Llc | éteres de celulose esterificados que compreendem grupos ftalila |
| JP7252882B2 (ja) | 2019-11-01 | 2023-04-05 | 信越化学工業株式会社 | ヒドロキシプロピルメチルセルロースアセテートサクシネートの製造方法 |
| JP7273691B2 (ja) * | 2019-11-01 | 2023-05-15 | 信越化学工業株式会社 | ヒドロキシプロピルメチルセルロースフタレートの製造方法 |
| JP7399061B2 (ja) * | 2020-10-01 | 2023-12-15 | 信越化学工業株式会社 | ヒドロキシプロピルメチルセルロースフタレートの製造方法 |
| JP7399060B2 (ja) | 2020-10-01 | 2023-12-15 | 信越化学工業株式会社 | ヒドロキシプロピルメチルセルロースアセテートサクシネートの製造方法 |
-
1969
- 1969-09-02 US US854789A patent/US3629237A/en not_active Expired - Lifetime
- 1969-09-03 GB GB43552/69A patent/GB1268658A/en not_active Expired
- 1969-09-12 FR FR6931091A patent/FR2020529A1/fr active Pending
- 1969-09-12 CH CH1384469A patent/CH523073A/de not_active IP Right Cessation
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0111103A3 (en) * | 1982-11-08 | 1985-06-19 | Fmc Corporation | Enteric coating for pharmaceutical dosage forms |
| GB2132887A (en) * | 1982-11-15 | 1984-07-18 | Procter & Gamble | Enteric-coated anti-inflammatory compositions |
| GB2285989A (en) * | 1994-01-28 | 1995-08-02 | Merck Frosst Canada Inc | Aqueous formulations for enteric coatings |
Also Published As
| Publication number | Publication date |
|---|---|
| US3629237A (en) | 1971-12-21 |
| FR2020529A1 (https=) | 1970-07-17 |
| DE1946170A1 (de) | 1970-03-19 |
| CH523073A (de) | 1972-05-31 |
| DE1946170B2 (de) | 1975-10-30 |
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