GB1229967A - - Google Patents
Info
- Publication number
- GB1229967A GB1229967A GB1229967DA GB1229967A GB 1229967 A GB1229967 A GB 1229967A GB 1229967D A GB1229967D A GB 1229967DA GB 1229967 A GB1229967 A GB 1229967A
- Authority
- GB
- United Kingdom
- Prior art keywords
- water
- oil
- emulsions
- types
- lipid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000839 emulsion Substances 0.000 abstract 2
- 150000002632 lipids Chemical class 0.000 abstract 2
- LOUPRKONTZGTKE-LHHVKLHASA-N quinidine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@H]2[C@@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-LHHVKLHASA-N 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- BPIUIOXAFBGMNB-UHFFFAOYSA-N 1-hexoxyhexane Chemical compound CCCCCCOCCCCCC BPIUIOXAFBGMNB-UHFFFAOYSA-N 0.000 abstract 1
- 239000011149 active material Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- LOUPRKONTZGTKE-UHFFFAOYSA-N cinchonine Natural products C1C(C(C2)C=C)CCN2C1C(O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-UHFFFAOYSA-N 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000006185 dispersion Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- ZEAJXCPGHPJVNP-UHFFFAOYSA-N fenyramidol Chemical compound C=1C=CC=CC=1C(O)CNC1=CC=CC=N1 ZEAJXCPGHPJVNP-UHFFFAOYSA-N 0.000 abstract 1
- 229960000555 fenyramidol Drugs 0.000 abstract 1
- UYXAWHWODHRRMR-UHFFFAOYSA-N hexobarbital Chemical compound O=C1N(C)C(=O)NC(=O)C1(C)C1=CCCCC1 UYXAWHWODHRRMR-UHFFFAOYSA-N 0.000 abstract 1
- 229960002456 hexobarbital Drugs 0.000 abstract 1
- IMYZQPCYWPFTAG-IQJOONFLSA-N mecamylamine Chemical compound C1C[C@@H]2C(C)(C)[C@@](NC)(C)[C@H]1C2 IMYZQPCYWPFTAG-IQJOONFLSA-N 0.000 abstract 1
- 229960002525 mecamylamine Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000008251 pharmaceutical emulsion Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 229960001404 quinidine Drugs 0.000 abstract 1
- KKNIUBFRGPFELP-UHFFFAOYSA-N secretolin Chemical compound N=1C=CNC=1CC(N)C(=O)NC(CO)C(=O)NC(CC(O)=O)C(=O)NCC(=O)NC(C(C)O)C(=O)NC(C(=O)NC(C(=O)NC(CO)C(=O)NC(CCC(O)=O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(O)=O)C(=O)NC(CO)C(=O)NC(C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(O)=O)C(C)O)CC1=CC=CC=C1 KKNIUBFRGPFELP-UHFFFAOYSA-N 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1215967 | 1967-09-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1229967A true GB1229967A (enrdf_load_stackoverflow) | 1971-04-28 |
Family
ID=20295252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1229967D Expired GB1229967A (enrdf_load_stackoverflow) | 1967-09-01 | 1968-08-30 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | USRE32393F1 (enrdf_load_stackoverflow) |
| DE (1) | DE1792410B2 (enrdf_load_stackoverflow) |
| DK (1) | DK129272B (enrdf_load_stackoverflow) |
| FR (2) | FR1593013A (enrdf_load_stackoverflow) |
| GB (1) | GB1229967A (enrdf_load_stackoverflow) |
| NL (1) | NL6812429A (enrdf_load_stackoverflow) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4613614A (en) * | 1983-07-05 | 1986-09-23 | The Green Cross Corporation | Prostaglandin I2 ester and fat emulsion containing the same |
| DE4107153A1 (de) * | 1991-03-06 | 1992-09-10 | Gregor Cevc | Praeparat zur wirkstoffapplikation in kleinsttroepfchenform |
| DE4107152A1 (de) * | 1991-03-06 | 1992-09-10 | Gregor Cevc | Praeparate zur nichtinvasiven verabreichung von antidiabetica |
| US8389551B2 (en) | 2006-05-23 | 2013-03-05 | Fermenta Biotech (Uk) Limited | Optical enantiomers of phenyramidol and process for chiral synthesis |
| WO2020101585A1 (en) * | 2018-11-16 | 2020-05-22 | Santa Farma İlaç Sanayi̇ A.Ş. | Solid oral pharmaceutical compositions comprising phenyramidol or salts thereof |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8004580L (sv) * | 1980-06-19 | 1981-12-20 | Draco Ab | Farmaceutisk beredning |
| US4889525A (en) | 1982-08-17 | 1989-12-26 | Adamantech, Inc. | Sensitization of hypoxic tumor cells and control of growth thereof |
| DE3339236A1 (de) * | 1983-10-28 | 1985-05-09 | Bayer Ag | Arzneimittelzubereitung |
| DE3515335C2 (de) * | 1985-04-27 | 1995-01-26 | Bayer Ag | Arzneizubereitung enthaltend Dihydropyridine und Verfahren zu ihrer Herstellung |
| CA1338736C (fr) * | 1986-12-05 | 1996-11-26 | Roger Baurain | Microcristaux comportant une substance active presentant une affinite pour les phospholipides, et au moins un phospholipide, procede de preparation |
| US5229422A (en) * | 1987-09-07 | 1993-07-20 | Teijin Limited | Extemporaneous preparation type kit of a pharmaceutical substance-containing fat emulsion |
| US4874605A (en) | 1987-11-27 | 1989-10-17 | Hoechst-Roussel Pharmaceuticals Inc. | Stabilized delayed release emulsion |
| DK159807C (da) * | 1989-02-27 | 1992-06-29 | Gunnar Kjems | Anvendelse af calciumsaltholdige emulsioner til fremstilling af orale midler til forebyggelse eller behandling af calciummangel hos kvaeg, isaer ved kaelvningsfeber |
| WO1990014837A1 (en) * | 1989-05-25 | 1990-12-13 | Chiron Corporation | Adjuvant formulation comprising a submicron oil droplet emulsion |
| US5314685A (en) * | 1992-05-11 | 1994-05-24 | Agouron Pharmaceuticals, Inc. | Anhydrous formulations for administering lipophilic agents |
| JP3187622B2 (ja) * | 1993-10-07 | 2001-07-11 | カネボウ株式会社 | リポソーム |
| GB9405593D0 (en) * | 1994-03-22 | 1994-05-11 | Zeneca Ltd | Pharmaceutical compositions |
| US20020173547A1 (en) * | 1994-03-22 | 2002-11-21 | Jones Christopher Buchan | Pharmaceuticals compositions |
| MY113046A (en) * | 1994-03-22 | 2001-11-30 | Astrazeneca Uk Ltd | Pharmaceutical compositions |
| US5731356A (en) * | 1994-03-22 | 1998-03-24 | Zeneca Limited | Pharmaceutical compositions of propofol and edetate |
| US5851510A (en) * | 1994-05-16 | 1998-12-22 | The Board Of Regents Of The University Of Michigan | Hepatocyte-selective oil-in-water emulsion |
| US5635536A (en) * | 1994-12-07 | 1997-06-03 | Pharmacia & Upjohn Aktiebolag | Emulsion suitable for administering a sphingolipid |
| US5560931A (en) * | 1995-02-14 | 1996-10-01 | Nawosystems L.L.C. | Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids |
| US5616342A (en) * | 1995-04-11 | 1997-04-01 | Pdt, Inc. | Emulsioin suitable for administering a poorly water-soluble photosensitizing compound and use thereof |
| US6465016B2 (en) * | 1996-08-22 | 2002-10-15 | Research Triangle Pharmaceuticals | Cyclosporiine particles |
| US7255877B2 (en) | 1996-08-22 | 2007-08-14 | Jagotec Ag | Fenofibrate microparticles |
| US6017545A (en) | 1998-02-10 | 2000-01-25 | Modi; Pankaj | Mixed micellar delivery system and method of preparation |
| US6221378B1 (en) | 1998-02-10 | 2001-04-24 | Generex Pharmaceuticals Incorporated | Mixed micellar delivery system and method of preparation |
| US6979456B1 (en) | 1998-04-01 | 2005-12-27 | Jagotec Ag | Anticancer compositions |
| ES2216517T3 (es) | 1998-05-29 | 2004-10-16 | Skyepharma Canada Inc. | Composiciones de microcapsulas termoprotegidas y procedimiento para su esterilizacion terminal con vapor. |
| ES2211151T3 (es) | 1998-08-19 | 2004-07-01 | Skyepharma Canada Inc. | Dispersiones acuosas inyectables de propofol. |
| RU2233654C2 (ru) | 1998-11-20 | 2004-08-10 | Ртп Фарма Инк. | Диспергируемые стабилизированные фосфолипидом микрочастицы |
| AU7984200A (en) * | 1999-09-21 | 2001-04-24 | Skyepharma Canada Inc. | Surface modified particulate compositions of biologically active substances |
| US8557861B2 (en) * | 2004-09-28 | 2013-10-15 | Mast Therapeutics, Inc. | Low oil emulsion compositions for delivering taxoids and other insoluble drugs |
| TWI376239B (en) * | 2006-02-01 | 2012-11-11 | Andrew Xian Chen | Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL292949A (enrdf_load_stackoverflow) * | ||||
| CA696819A (en) * | 1964-10-27 | Kelco Company | Edible compositions comprising oil-in-water emulsions | |
| CA659453A (en) * | 1963-03-12 | D. Mullins John | Aqueous solutions of fat soluble vitamins | |
| DE397396C (de) * | 1922-05-09 | 1924-06-20 | Chem Ind Basel | Verfahren zur Herstellung haltbarer Emulsionen oelloeslicher Arzneimittel |
| US2055083A (en) * | 1932-07-13 | 1936-09-22 | Winthrop Chem Co Inc | Pharmaceutical preparation |
| DE707580C (de) * | 1932-07-14 | 1941-06-26 | I G Farbenindustrie Akt Ges | Verfahren zur Herstellung von therapeutisch wirksame Stoffe enthaltenden Emulsionen zu Injektionszwecken |
| DE675966C (de) * | 1935-08-25 | 1939-05-23 | I G Farbenindustrie Akt Ges | Verfahren zur Herstellung klarer waessriger Loesungen von aetherischen OElen, Kampfer, Terpenen |
| DE711777C (de) * | 1937-09-21 | 1941-10-06 | I G Farbenindustrie Akt Ges | Verfahren zur Herstellung von waessrigen Loesungen oder Emulsionen von in Wasser schwer loeslichen physiologisch wirksamen Stoffen |
| US2303236A (en) * | 1941-06-10 | 1942-11-24 | Wm S Merrell Co | Emulsion |
| GB744376A (en) * | 1952-03-08 | 1956-02-08 | Merck & Co Inc | Vitamin emulsions |
| GB828312A (en) * | 1955-06-10 | 1960-02-17 | Donald Berthold Zilversmit | Fat composition |
| US2832721A (en) * | 1956-07-23 | 1958-04-29 | Merck & Co Inc | Vitamin emulsions |
| US2988484A (en) * | 1956-07-24 | 1961-06-13 | Drew & Co Inc E F | Alcohol soluble pharmaceutical compositions |
| US2853419A (en) * | 1956-09-07 | 1958-09-23 | Merck & Co Inc | Aqueous fat emulsions and process for preparing the same |
| US2867565A (en) * | 1957-08-12 | 1959-01-06 | Feinstone Wolffe Harry | Sulfonamide composition comprising a lipid-aqueous emulsion carrier |
| US2972565A (en) * | 1958-04-04 | 1961-02-21 | Univ Tennessee Res Corp | Fat composition |
| US3085939A (en) * | 1959-05-11 | 1963-04-16 | Upjohn Co | Oil-in-water emulsion for oral administration, and process for preparation |
| US3044931A (en) * | 1960-01-27 | 1962-07-17 | Geigy Chem Corp | Aryloxy acetic acid amides: process for parenteral application |
| US3096249A (en) * | 1960-05-10 | 1963-07-02 | Samuel J Prigal | Emulsion composition |
| GB914894A (en) * | 1960-08-12 | 1963-01-09 | Beecham Res Lab | Injectable pharmaceutical media |
| CA725596A (en) * | 1960-08-26 | 1966-01-11 | J. Wretlind Arvid | Method of preparing intravenously injectable fat emulsions free from side reactions or complications |
| NL269002A (enrdf_load_stackoverflow) * | 1960-09-06 | |||
| US3089823A (en) * | 1961-09-05 | 1963-05-14 | Eastman Kodak Co | Aqueous vitamin a oil emulsion |
| US3216897A (en) * | 1961-11-02 | 1965-11-09 | Air Reduction | Injectable anesthetic |
| US3185625A (en) * | 1961-11-08 | 1965-05-25 | Brown Ethan Allan | Injectionable substances |
| GB1044623A (en) * | 1961-11-16 | 1966-10-05 | Marfleet Refining Company Ltd | Improvements in and relating to glyceride esters and/or ethyl fatty esters |
| GB962209A (en) * | 1962-04-19 | 1964-07-01 | Upjohn Co | Multi-vitamin compositions containing fluorides |
| GB1015251A (en) * | 1963-03-12 | 1965-12-31 | Glaxo Lab Ltd | Aqueous pharmaceutical compositions in capsule form |
| DE1229677B (de) * | 1963-10-25 | 1966-12-01 | Nat Res Dev | Verfahren zur Herstellung injizierbarer, Antigene enthaltender Emulsionen |
| GB1080994A (en) * | 1963-10-25 | 1967-08-31 | Nat Res Dev | Injectable emulsions containing antigens |
| CH437995A (de) * | 1963-11-01 | 1967-06-15 | Hoffmann La Roche | Verfahren zur Gewinnung von lipophile Substanzen enthaltenden Präparaten |
| FR3707M (fr) * | 1963-11-05 | 1965-11-22 | Belge Produits Chimiques Sa | Association de la carnitine a des émulsions lipidiques. |
| US3318770A (en) * | 1964-01-16 | 1967-05-09 | Geigy Chem Corp | Intravenously injectable anesthetic composition |
| US3538216A (en) * | 1964-02-20 | 1970-11-03 | Lab De Rech Physiques S A R L | Injectable compositions of a drug suspended in an emulsion |
| GB1035701A (en) * | 1964-03-03 | 1966-07-13 | Merck & Co Inc | Emulsions suitable for use as adjuvants for immunological agents |
| US3384545A (en) * | 1965-03-09 | 1968-05-21 | Hoffmann La Roche | Injectable aqueous emulsions of fat soluble vitamins |
| US3356575A (en) * | 1965-04-13 | 1967-12-05 | Leo Ab | Autosterile injectable iodinated oil X-ray contrast medium |
| GB1081796A (en) * | 1965-08-13 | 1967-08-31 | Wright Fleming Inst Of Microbi | Improvements in or relating to oily adjuvants for water-in-oil emulsions of antigenic materials |
| US3995118A (en) * | 1975-07-03 | 1976-11-30 | Bell Telephone Laboratories, Incorporated | Call processing restoration arrangement for a telephone switching system |
-
1968
- 1968-08-29 DE DE1792410A patent/DE1792410B2/de active Pending
- 1968-08-30 NL NL6812429A patent/NL6812429A/xx unknown
- 1968-08-30 DK DK420968AA patent/DK129272B/da not_active IP Right Cessation
- 1968-08-30 GB GB1229967D patent/GB1229967A/en not_active Expired
- 1968-09-02 FR FR1593013D patent/FR1593013A/fr not_active Expired
- 1968-11-28 FR FR175712A patent/FR8152M/fr not_active Expired
-
1984
- 1984-08-14 US US06605760 patent/USRE32393F1/en not_active Expired - Lifetime
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4613614A (en) * | 1983-07-05 | 1986-09-23 | The Green Cross Corporation | Prostaglandin I2 ester and fat emulsion containing the same |
| DE4107153A1 (de) * | 1991-03-06 | 1992-09-10 | Gregor Cevc | Praeparat zur wirkstoffapplikation in kleinsttroepfchenform |
| DE4107152A1 (de) * | 1991-03-06 | 1992-09-10 | Gregor Cevc | Praeparate zur nichtinvasiven verabreichung von antidiabetica |
| US8389551B2 (en) | 2006-05-23 | 2013-03-05 | Fermenta Biotech (Uk) Limited | Optical enantiomers of phenyramidol and process for chiral synthesis |
| WO2020101585A1 (en) * | 2018-11-16 | 2020-05-22 | Santa Farma İlaç Sanayi̇ A.Ş. | Solid oral pharmaceutical compositions comprising phenyramidol or salts thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| FR1593013A (enrdf_load_stackoverflow) | 1970-05-25 |
| DE1792410A1 (de) | 1971-11-11 |
| DE1792410B2 (de) | 1980-03-13 |
| DK129272B (da) | 1974-09-23 |
| USRE32393F1 (en) | 1990-05-29 |
| FR8152M (enrdf_load_stackoverflow) | 1970-08-17 |
| USRE32393E (en) | 1987-04-07 |
| NL6812429A (enrdf_load_stackoverflow) | 1969-03-04 |
| DK129272C (enrdf_load_stackoverflow) | 1975-02-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PE20 | Patent expired after termination of 20 years |