GB1229967A - - Google Patents

Info

Publication number
GB1229967A
GB1229967A GB1229967DA GB1229967A GB 1229967 A GB1229967 A GB 1229967A GB 1229967D A GB1229967D A GB 1229967DA GB 1229967 A GB1229967 A GB 1229967A
Authority
GB
United Kingdom
Prior art keywords
water
oil
emulsions
types
lipid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GB1229967A publication Critical patent/GB1229967A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1,229,967. Pharmaceutical emulsions. APOTEKSVARUCENTRALEN VITRUM APOTEKARE A.B. 30 Aug., 1968 [1 Sept., 1967], No. 41622/68. Heading A5B. Pharmaceutical compositions for enteral, parenteral and intranasal application comprise an oil-soluble therapeutic and/or diognostic agent dispersed in a diluent comprising an emulsion or dispersion of a pharmaceutically inert lipid and water, at least 50% by weight of the active material being in the lipid phase. Oil-in-water and water-in-oil emulsions are included and both types may comprise conventional stabilizing agents, e.g. phosphatides. Numerous types of medicaments are mentioned and examples relate to preparations comprising phenyramidol, hexobarbital, hexyl ether, mecamylamine and quinidine.
GB1229967D 1967-09-01 1968-08-30 Expired GB1229967A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE1215967 1967-09-01

Publications (1)

Publication Number Publication Date
GB1229967A true GB1229967A (en) 1971-04-28

Family

ID=20295252

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1229967D Expired GB1229967A (en) 1967-09-01 1968-08-30

Country Status (6)

Country Link
US (1) USRE32393F1 (en)
DE (1) DE1792410B2 (en)
DK (1) DK129272B (en)
FR (2) FR1593013A (en)
GB (1) GB1229967A (en)
NL (1) NL6812429A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4613614A (en) * 1983-07-05 1986-09-23 The Green Cross Corporation Prostaglandin I2 ester and fat emulsion containing the same
DE4107153A1 (en) * 1991-03-06 1992-09-10 Gregor Cevc Compsns. for application of active agents
DE4107152A1 (en) * 1991-03-06 1992-09-10 Gregor Cevc Compsns. for application of active agents
US8389551B2 (en) 2006-05-23 2013-03-05 Fermenta Biotech (Uk) Limited Optical enantiomers of phenyramidol and process for chiral synthesis
WO2020101585A1 (en) * 2018-11-16 2020-05-22 Santa Farma İlaç Sanayi̇ A.Ş. Solid oral pharmaceutical compositions comprising phenyramidol or salts thereof

Families Citing this family (30)

* Cited by examiner, † Cited by third party
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SE8004580L (en) * 1980-06-19 1981-12-20 Draco Ab PHARMACEUTICAL PREPARATION
US4889525A (en) 1982-08-17 1989-12-26 Adamantech, Inc. Sensitization of hypoxic tumor cells and control of growth thereof
DE3339236A1 (en) * 1983-10-28 1985-05-09 Bayer Ag PREPARATION OF MEDICINAL PRODUCTS
DE3515335C2 (en) * 1985-04-27 1995-01-26 Bayer Ag Pharmaceutical preparation containing dihydropyridines and process for their preparation
CA1338736C (en) * 1986-12-05 1996-11-26 Roger Baurain Microcrystals containing an active ingredient with affinity for phospholipids and at least one phospholipid; process for preparing the same
US5229422A (en) * 1987-09-07 1993-07-20 Teijin Limited Extemporaneous preparation type kit of a pharmaceutical substance-containing fat emulsion
US4874605A (en) 1987-11-27 1989-10-17 Hoechst-Roussel Pharmaceuticals Inc. Stabilized delayed release emulsion
DK159807C (en) * 1989-02-27 1992-06-29 Gunnar Kjems APPLICATION OF CALCIUM-SUSTAINABLE EMULSIONS FOR THE PREPARATION OF ORAL AGENTS FOR PREVENTION OR TREATMENT OF CALCIUM LACK OF Cattle, especially by calving fever
HU212924B (en) * 1989-05-25 1996-12-30 Chiron Corp Adjuvant formulation comprising a submicron oil droplet emulsion
US5314685A (en) * 1992-05-11 1994-05-24 Agouron Pharmaceuticals, Inc. Anhydrous formulations for administering lipophilic agents
JP3187622B2 (en) * 1993-10-07 2001-07-11 カネボウ株式会社 Liposome
US5731355A (en) * 1994-03-22 1998-03-24 Zeneca Limited Pharmaceutical compositions of propofol and edetate
US20020173547A1 (en) * 1994-03-22 2002-11-21 Jones Christopher Buchan Pharmaceuticals compositions
MY113046A (en) * 1994-03-22 2001-11-30 Astrazeneca Uk Ltd Pharmaceutical compositions
GB9405593D0 (en) * 1994-03-22 1994-05-11 Zeneca Ltd Pharmaceutical compositions
US5851510A (en) * 1994-05-16 1998-12-22 The Board Of Regents Of The University Of Michigan Hepatocyte-selective oil-in-water emulsion
US5635536A (en) * 1994-12-07 1997-06-03 Pharmacia & Upjohn Aktiebolag Emulsion suitable for administering a sphingolipid
US5560931A (en) * 1995-02-14 1996-10-01 Nawosystems L.L.C. Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids
US5616342A (en) * 1995-04-11 1997-04-01 Pdt, Inc. Emulsioin suitable for administering a poorly water-soluble photosensitizing compound and use thereof
US6465016B2 (en) * 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
US7255877B2 (en) 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
US6017545A (en) 1998-02-10 2000-01-25 Modi; Pankaj Mixed micellar delivery system and method of preparation
US6221378B1 (en) 1998-02-10 2001-04-24 Generex Pharmaceuticals Incorporated Mixed micellar delivery system and method of preparation
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
CN1245955C (en) 1998-05-29 2006-03-22 斯凯伊药品加拿大公司 Thermoprotected microparticle compositions and process for terminal steam sterilization thereof
AU759641B2 (en) 1998-08-19 2003-04-17 Skyepharma Canada Inc. Injectable aqueous dispersions of propofol
US7939105B2 (en) 1998-11-20 2011-05-10 Jagotec Ag Process for preparing a rapidly dispersing solid drug dosage form
CN1174741C (en) * 1999-09-21 2004-11-10 Rtp药品公司 Surface modified particulate compositions of biologically active substances
US8557861B2 (en) * 2004-09-28 2013-10-15 Mast Therapeutics, Inc. Low oil emulsion compositions for delivering taxoids and other insoluble drugs
TWI376239B (en) * 2006-02-01 2012-11-11 Andrew Xian Chen Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA696819A (en) * 1964-10-27 Kelco Company Edible compositions comprising oil-in-water emulsions
NL292949A (en) *
CA659453A (en) * 1963-03-12 D. Mullins John Aqueous solutions of fat soluble vitamins
DE397396C (en) * 1922-05-09 1924-06-20 Chem Ind Basel Process for making long-lasting emulsions of oil-soluble drugs
US2055083A (en) * 1932-07-13 1936-09-22 Winthrop Chem Co Inc Pharmaceutical preparation
DE707580C (en) * 1932-07-14 1941-06-26 I G Farbenindustrie Akt Ges Process for the preparation of emulsions containing therapeutically active substances for injection purposes
DE675966C (en) * 1935-08-25 1939-05-23 I G Farbenindustrie Akt Ges Process for the production of clear aqueous solutions of ethereal oils, camphor, terpenes
DE711777C (en) * 1937-09-21 1941-10-06 I G Farbenindustrie Akt Ges Process for the production of aqueous solutions or emulsions of poorly soluble physiologically active substances in water
US2303236A (en) * 1941-06-10 1942-11-24 Wm S Merrell Co Emulsion
GB744376A (en) * 1952-03-08 1956-02-08 Merck & Co Inc Vitamin emulsions
GB828312A (en) * 1955-06-10 1960-02-17 Donald Berthold Zilversmit Fat composition
US2832721A (en) * 1956-07-23 1958-04-29 Merck & Co Inc Vitamin emulsions
US2988484A (en) * 1956-07-24 1961-06-13 Drew & Co Inc E F Alcohol soluble pharmaceutical compositions
US2853419A (en) * 1956-09-07 1958-09-23 Merck & Co Inc Aqueous fat emulsions and process for preparing the same
US2867565A (en) * 1957-08-12 1959-01-06 Feinstone Wolffe Harry Sulfonamide composition comprising a lipid-aqueous emulsion carrier
US2972565A (en) * 1958-04-04 1961-02-21 Univ Tennessee Res Corp Fat composition
US3085939A (en) * 1959-05-11 1963-04-16 Upjohn Co Oil-in-water emulsion for oral administration, and process for preparation
US3044931A (en) * 1960-01-27 1962-07-17 Geigy Chem Corp Aryloxy acetic acid amides: process for parenteral application
US3096249A (en) * 1960-05-10 1963-07-02 Samuel J Prigal Emulsion composition
GB914894A (en) * 1960-08-12 1963-01-09 Beecham Res Lab Injectable pharmaceutical media
CA725596A (en) * 1960-08-26 1966-01-11 J. Wretlind Arvid Method of preparing intravenously injectable fat emulsions free from side reactions or complications
NL269002A (en) * 1960-09-06
US3089823A (en) * 1961-09-05 1963-05-14 Eastman Kodak Co Aqueous vitamin a oil emulsion
US3216897A (en) * 1961-11-02 1965-11-09 Air Reduction Injectable anesthetic
US3185625A (en) * 1961-11-08 1965-05-25 Brown Ethan Allan Injectionable substances
GB1044623A (en) * 1961-11-16 1966-10-05 Marfleet Refining Company Ltd Improvements in and relating to glyceride esters and/or ethyl fatty esters
GB962209A (en) * 1962-04-19 1964-07-01 Upjohn Co Multi-vitamin compositions containing fluorides
GB1015251A (en) * 1963-03-12 1965-12-31 Glaxo Lab Ltd Aqueous pharmaceutical compositions in capsule form
GB1080994A (en) * 1963-10-25 1967-08-31 Nat Res Dev Injectable emulsions containing antigens
DE1229677B (en) * 1963-10-25 1966-12-01 Nat Res Dev Process for the preparation of injectable emulsions containing antigens
CH437995A (en) * 1963-11-01 1967-06-15 Hoffmann La Roche Process for the production of preparations containing lipophilic substances
FR3707M (en) * 1963-11-05 1965-11-22 Belge Produits Chimiques Sa Association of carnitine with lipid emulsions.
US3318770A (en) * 1964-01-16 1967-05-09 Geigy Chem Corp Intravenously injectable anesthetic composition
US3538216A (en) * 1964-02-20 1970-11-03 Lab De Rech Physiques S A R L Injectable compositions of a drug suspended in an emulsion
GB1035701A (en) * 1964-03-03 1966-07-13 Merck & Co Inc Emulsions suitable for use as adjuvants for immunological agents
US3384545A (en) * 1965-03-09 1968-05-21 Hoffmann La Roche Injectable aqueous emulsions of fat soluble vitamins
US3356575A (en) * 1965-04-13 1967-12-05 Leo Ab Autosterile injectable iodinated oil X-ray contrast medium
GB1081796A (en) * 1965-08-13 1967-08-31 Wright Fleming Inst Of Microbi Improvements in or relating to oily adjuvants for water-in-oil emulsions of antigenic materials
US3995118A (en) * 1975-07-03 1976-11-30 Bell Telephone Laboratories, Incorporated Call processing restoration arrangement for a telephone switching system

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4613614A (en) * 1983-07-05 1986-09-23 The Green Cross Corporation Prostaglandin I2 ester and fat emulsion containing the same
DE4107153A1 (en) * 1991-03-06 1992-09-10 Gregor Cevc Compsns. for application of active agents
DE4107152A1 (en) * 1991-03-06 1992-09-10 Gregor Cevc Compsns. for application of active agents
US8389551B2 (en) 2006-05-23 2013-03-05 Fermenta Biotech (Uk) Limited Optical enantiomers of phenyramidol and process for chiral synthesis
WO2020101585A1 (en) * 2018-11-16 2020-05-22 Santa Farma İlaç Sanayi̇ A.Ş. Solid oral pharmaceutical compositions comprising phenyramidol or salts thereof

Also Published As

Publication number Publication date
USRE32393F1 (en) 1990-05-29
USRE32393E (en) 1987-04-07
DK129272B (en) 1974-09-23
DE1792410A1 (en) 1971-11-11
NL6812429A (en) 1969-03-04
DE1792410B2 (en) 1980-03-13
FR1593013A (en) 1970-05-25
DK129272C (en) 1975-02-10
FR8152M (en) 1970-08-17

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PE20 Patent expired after termination of 20 years