FR2812553B1 - Combinaison de collagene et de matiere osseuse pour la reparation de lesions articulaires - Google Patents

Combinaison de collagene et de matiere osseuse pour la reparation de lesions articulaires

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Publication number
FR2812553B1
FR2812553B1 FR0108874A FR0108874A FR2812553B1 FR 2812553 B1 FR2812553 B1 FR 2812553B1 FR 0108874 A FR0108874 A FR 0108874A FR 0108874 A FR0108874 A FR 0108874A FR 2812553 B1 FR2812553 B1 FR 2812553B1
Authority
FR
France
Prior art keywords
collagen
repair
combination
bone material
joint injuries
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0108874A
Other languages
English (en)
Other versions
FR2812553A1 (fr
Inventor
Peter Geistlich
Lothar Schlosser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ed Geistlich Soehne AG fuer Chemische Industrie
Original Assignee
Ed Geistlich Soehne AG fuer Chemische Industrie
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Filing date
Publication date
Application filed by Ed Geistlich Soehne AG fuer Chemische Industrie filed Critical Ed Geistlich Soehne AG fuer Chemische Industrie
Publication of FR2812553A1 publication Critical patent/FR2812553A1/fr
Application granted granted Critical
Publication of FR2812553B1 publication Critical patent/FR2812553B1/fr
Anticipated expiration legal-status Critical
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    • A61F2240/00Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2240/001Designing or manufacturing processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00365Proteins; Polypeptides; Degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00365Proteins; Polypeptides; Degradation products thereof
    • A61F2310/00383Gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389The prosthesis being coated or covered with a particular material
    • A61F2310/00976Coating or prosthesis-covering structure made of proteins or of polypeptides, e.g. of bone morphogenic proteins BMP or of transforming growth factors TGF
    • A61F2310/00982Coating made of collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents
    • A61L2300/414Growth factors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cell Biology (AREA)
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  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
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  • Rheumatology (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Inorganic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR0108874A 2000-07-19 2001-07-04 Combinaison de collagene et de matiere osseuse pour la reparation de lesions articulaires Expired - Fee Related FR2812553B1 (fr)

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Families Citing this family (109)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050186673A1 (en) * 1995-02-22 2005-08-25 Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie Collagen carrier of therapeutic genetic material, and method
US8083745B2 (en) * 2001-05-25 2011-12-27 Conformis, Inc. Surgical tools for arthroplasty
US8480754B2 (en) 2001-05-25 2013-07-09 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
US8735773B2 (en) 2007-02-14 2014-05-27 Conformis, Inc. Implant device and method for manufacture
US20090222103A1 (en) * 2001-05-25 2009-09-03 Conformis, Inc. Articular Implants Providing Lower Adjacent Cartilage Wear
US8545569B2 (en) 2001-05-25 2013-10-01 Conformis, Inc. Patient selectable knee arthroplasty devices
US7618451B2 (en) * 2001-05-25 2009-11-17 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty
US8882847B2 (en) 2001-05-25 2014-11-11 Conformis, Inc. Patient selectable knee joint arthroplasty devices
US20070100462A1 (en) * 2001-05-25 2007-05-03 Conformis, Inc Joint Arthroplasty Devices
US20110071645A1 (en) * 2009-02-25 2011-03-24 Ray Bojarski Patient-adapted and improved articular implants, designs and related guide tools
US7468075B2 (en) 2001-05-25 2008-12-23 Conformis, Inc. Methods and compositions for articular repair
US8556983B2 (en) 2001-05-25 2013-10-15 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
US7534263B2 (en) * 2001-05-25 2009-05-19 Conformis, Inc. Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty
US20110071802A1 (en) * 2009-02-25 2011-03-24 Ray Bojarski Patient-adapted and improved articular implants, designs and related guide tools
US20070233269A1 (en) * 2001-05-25 2007-10-04 Conformis, Inc. Interpositional Joint Implant
US9603711B2 (en) * 2001-05-25 2017-03-28 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
US20030055502A1 (en) 2001-05-25 2003-03-20 Philipp Lang Methods and compositions for articular resurfacing
US8771365B2 (en) * 2009-02-25 2014-07-08 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs, and related tools
US8858981B2 (en) * 1997-10-10 2014-10-14 Ed. Geistlich Soehne Fuer Chemistrie Industrie Bone healing material comprising matrix carrying bone-forming cells
US20030180263A1 (en) * 2002-02-21 2003-09-25 Peter Geistlich Resorbable extracellular matrix for reconstruction of bone
US20050186283A1 (en) * 1997-10-10 2005-08-25 Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie Collagen carrier of therapeutic genetic material, and method
US9034315B2 (en) * 1997-10-10 2015-05-19 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Cell-charged multi-layer collagen membrane
US7239908B1 (en) * 1998-09-14 2007-07-03 The Board Of Trustees Of The Leland Stanford Junior University Assessing the condition of a joint and devising treatment
US7184814B2 (en) * 1998-09-14 2007-02-27 The Board Of Trustees Of The Leland Stanford Junior University Assessing the condition of a joint and assessing cartilage loss
WO2000035346A2 (fr) 1998-09-14 2000-06-22 Stanford University Estimation de l'etat d'une articulation et prevention de lesions
ITVI20000025U1 (it) * 2000-04-07 2001-10-07 Tecres Spa Dispositivo distanziatore temporaneo per il trattamento chirurgico del ginocchio
EP1322225B1 (fr) * 2000-09-14 2009-03-25 The Board Of Trustees Of The Leland Stanford Junior University Evaluation de l'etat d'une articulation et traitement afferent
US20020114795A1 (en) * 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US8439926B2 (en) 2001-05-25 2013-05-14 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
US8951260B2 (en) * 2001-05-25 2015-02-10 Conformis, Inc. Surgical cutting guide
BR0307033A (pt) * 2002-01-22 2004-12-07 Pfizer ácidos 3-(imidazolil)-2-aminopropanóicos para o uso como inibidores tafi-a para o tratamento de doenças trombóticas
US7166133B2 (en) 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
DE60336002D1 (de) 2002-10-07 2011-03-24 Conformis Inc Minimal invasives gelenkimplantat mit einer den gelenkflächen angepassten dreidimensionalen geometrie
EP1558181B1 (fr) 2002-11-07 2015-08-26 ConforMIS, Inc. Procedes pour determiner les dimensions et formes de menisques, et pour mettre au point un traitement
JP2004173941A (ja) * 2002-11-27 2004-06-24 Olympus Corp カルシウム傾斜材料とその製造方法
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US7488348B2 (en) 2003-05-16 2009-02-10 Musculoskeletal Transplant Foundation Cartilage allograft plug
US20050020506A1 (en) * 2003-07-25 2005-01-27 Drapeau Susan J. Crosslinked compositions comprising collagen and demineralized bone matrix, methods of making and methods of use
US20070190101A1 (en) * 2004-03-31 2007-08-16 Chunlin Yang Flowable bone grafts
JP2007537200A (ja) * 2004-05-14 2007-12-20 ハンス−ディートリヒ・ポラシェグ タウロリジン製剤及び投与:細菌マイクロフィルム形成に対する治療処置及び抗菌保護
DE102004044102B4 (de) * 2004-09-07 2014-07-31 Technische Universität Dresden Implantat zur Behandlung von osteochondralen Defekten, sowie Verfahren zu dessen Herstellung
US20090319045A1 (en) 2004-10-12 2009-12-24 Truncale Katherine G Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
US8114841B2 (en) * 2004-10-14 2012-02-14 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhPDGF-BB and a biocompatible matrix
CA2912012C (fr) 2005-05-05 2018-05-29 Sensient Flavors Inc. Production de beta-glucanes et de mannanes
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
AU2006292224B2 (en) 2005-09-19 2013-08-01 Histogenics Corporation Cell-support matrix and a method for preparation thereof
US8685092B2 (en) 2005-10-27 2014-04-01 Andrey Fedorovich Panasyuk Material for osteoplasty and tissue engineering
EP1941916B1 (fr) * 2005-10-27 2012-08-15 Savaschuk, Dmitry Alekseevich Procede de fabrication de materiaux biologiques a partir de tissus osseux et materiau d'osteoplastie et d'ingenierie de tissus obtenu au moyen de ce procede
US8623026B2 (en) 2006-02-06 2014-01-07 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools incorporating anatomical relief
CN101420911B (zh) 2006-02-06 2012-07-18 康复米斯公司 患者可选择的关节成形术装置和手术器具
WO2007092622A2 (fr) * 2006-02-09 2007-08-16 Biomimetic Therapeutics, Inc. Compositions et méthodes pour le traitement d'os
US20100209470A1 (en) * 2006-05-01 2010-08-19 Warsaw Orthopedic, Inc. An Indiana Corporation Demineralized bone matrix devices
US7771741B2 (en) * 2006-05-01 2010-08-10 Warsaw Orthopedic, Inc Demineralized bone matrix devices
US8506983B2 (en) * 2006-05-01 2013-08-13 Warsaw Orthopedic, Inc. Bone filler material
US7838022B2 (en) 2006-05-01 2010-11-23 Warsaw Orthopedic, Inc Malleable implants containing demineralized bone matrix
US9161967B2 (en) * 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
AU2007269712B2 (en) 2006-06-30 2013-02-07 Biomimetic Therapeutics, Llc PDGF-biomatrix compositions and methods for treating rotator cuff injuries
US20100040667A1 (en) * 2006-09-07 2010-02-18 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method of treating bone cancer
US8106008B2 (en) 2006-11-03 2012-01-31 Biomimetic Therapeutics, Inc. Compositions and methods for arthrodetic procedures
US20080125863A1 (en) * 2006-11-28 2008-05-29 Mckay William F Implant designs and methods of improving cartilage repair
US7718616B2 (en) * 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
EP2591756A1 (fr) * 2007-02-14 2013-05-15 Conformis, Inc. Dispositif d'implant et procédé de fabrication
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
US8062655B2 (en) * 2007-08-31 2011-11-22 Phillips Plastics Corporation Composite scaffold structure
WO2009100454A1 (fr) * 2008-02-07 2009-08-13 Biomimetic Therapeutics, Inc. Compositions et procédés associés à une ostéogenèse par distraction
DE102008010893B3 (de) * 2008-02-23 2009-07-09 Resorba Wundversorgung Gmbh & Co. Kg Implantat zum Einbringen in einen Alveolarraum
US8682052B2 (en) 2008-03-05 2014-03-25 Conformis, Inc. Implants for altering wear patterns of articular surfaces
EP2901969B1 (fr) * 2008-03-05 2018-07-04 ConforMIS, Inc. Procédé de fabrication d'un implant articulaire à bords concordants
EP2303193A4 (fr) * 2008-05-12 2012-03-21 Conformis Inc Dispositifs et procédés pour le traitement de facette et d autres articulations
US8870954B2 (en) 2008-09-09 2014-10-28 Biomimetic Therapeutics, Llc Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries
US9192695B2 (en) 2008-11-20 2015-11-24 Allosource Allografts combined with tissue derived stem cells for bone healing
KR101158473B1 (ko) * 2009-01-15 2012-06-20 코아스템(주) 연골줄기세포를 유효성분으로 포함하는 골질환 치료용 또는 항염증용 약제학적 조성물
US9017334B2 (en) 2009-02-24 2015-04-28 Microport Orthopedics Holdings Inc. Patient specific surgical guide locator and mount
US8808303B2 (en) 2009-02-24 2014-08-19 Microport Orthopedics Holdings Inc. Orthopedic surgical guide
US8808297B2 (en) 2009-02-24 2014-08-19 Microport Orthopedics Holdings Inc. Orthopedic surgical guide
WO2010099231A2 (fr) 2009-02-24 2010-09-02 Conformis, Inc. Systèmes automatisés de fabrication d'implants orthopédiques spécifiques au patient et instrumentation
EP2403514A4 (fr) * 2009-03-05 2012-11-14 Biomimetic Therapeutics Inc Compositions de facteur de croissance dérivé des plaquettes et méthodes de traitement de défauts ostéo-cartilagineux
JP5590619B2 (ja) * 2009-03-06 2014-09-17 国立大学法人 新潟大学 培養細胞が産生する石灰化物による骨形成・再生
AU2010236263A1 (en) 2009-04-16 2011-11-10 Conformis, Inc. Patient-specific joint arthroplasty devices for ligament repair
US20140286911A1 (en) 2013-03-15 2014-09-25 Allosource Cell repopulated collagen matrix for soft tissue repair and regeneration
CA2782137A1 (fr) * 2009-12-11 2011-06-16 Conformis, Inc. Implants orthopediques mis au point pour un patient et specifiques a un patient
BR112012020566B1 (pt) 2010-02-22 2021-09-21 Biomimetic Therapeutics, Llc Composição de fator de crescimento derivado de plaqueta
TWI403326B (zh) * 2010-04-22 2013-08-01 Univ Taipei Medical 促進硬骨分化之方法及其組合物,以及硬骨植入物及其製造方法
US20110262486A1 (en) * 2010-04-22 2011-10-27 Taipei Medical University Bone implant and manufacturing method thereof
AU2011329054B2 (en) 2010-11-15 2015-05-28 Zimmer Orthobiologics, Inc. Bone void fillers
US8551525B2 (en) 2010-12-23 2013-10-08 Biostructures, Llc Bone graft materials and methods
WO2012112702A2 (fr) 2011-02-15 2012-08-23 Conformis, Inc. Implants articulaires améliorés et adaptés aux patients, conceptions et outils de guidage correspondants
US8920511B2 (en) 2011-11-17 2014-12-30 Allosource Multi-piece machine graft systems and methods
US9162011B2 (en) 2011-12-19 2015-10-20 Allosource Flowable matrix compositions and methods
US9486226B2 (en) 2012-04-18 2016-11-08 Conformis, Inc. Tibial guides, tools, and techniques for resecting the tibial plateau
US9675471B2 (en) 2012-06-11 2017-06-13 Conformis, Inc. Devices, techniques and methods for assessing joint spacing, balancing soft tissues and obtaining desired kinematics for joint implant components
EP2958523B1 (fr) 2013-02-22 2020-04-22 AlloSource Compositions de mosaïque de cartilage et procédés afférents
US9289452B2 (en) 2013-03-07 2016-03-22 Allosource Consistent calcium content bone allograft systems and methods
US9168140B2 (en) 2013-03-15 2015-10-27 Allosource Perforated osteochondral allograft compositions
PL2853384T3 (pl) * 2013-09-27 2017-06-30 Skulle Implants Oy Sposób powlekania i powlekana powierzchnia
FR3020273B1 (fr) * 2014-04-25 2021-04-16 Biobank Procede de fabrication de pate osseuse
US9730796B2 (en) 2014-05-16 2017-08-15 Allosource Composite bone constructs and methods
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
US9238090B1 (en) 2014-12-24 2016-01-19 Fettech, Llc Tissue-based compositions
CA3177726A1 (fr) 2015-05-21 2016-11-24 Musculoskeletal Transplant Foundation Fibres osseuses corticales demineralisees modifiees
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
EP3621663A4 (fr) 2017-05-10 2021-01-27 Marquette University Biomatériaux médicaux et dentaires multiphases intégrés pour la reconstruction/régénération d'un seul tissu ou de plusieurs tissus
KR102632931B1 (ko) 2017-06-30 2024-02-05 알로소스 세포성 골 이식편 및 제조 및 사용 방법
RU2699994C1 (ru) * 2018-05-11 2019-09-12 Общество с ограниченной ответственностью "Кардиоплант" Биокомпозитный остеопластический матрикс
RU2693606C1 (ru) * 2018-06-05 2019-07-03 Общество с ограниченной ответственностью "Матрифлекс" Способ получения и применения высокоочищенного минерального матрикса в виде сегментов и гранул с остеоиндуктивными свойствами для замещения костных дефектов
CN112999422A (zh) * 2021-03-23 2021-06-22 潍坊奥精医学研究有限公司 一种骨修复材料的制备方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US545465A (en) 1895-09-03 Sealed package
DE2967060D1 (en) * 1979-12-18 1984-07-19 Oscobal Ag Bone replacement material and process for producing a bone replacement material
US4440750A (en) * 1982-02-12 1984-04-03 Collagen Corporation Osteogenic composition and method
US4485096A (en) * 1982-02-26 1984-11-27 Massachusetts Institute Of Technology Tissue-equivalent and method for preparation thereof
CA1259914A (fr) * 1984-07-06 1989-09-26 Donald G. Wallace Methodes de reparation des os a l'aide de collagene
GB8514055D0 (en) * 1985-06-04 1985-07-10 Geistlich Soehne Ag Chemical substance
GB8813033D0 (en) * 1988-06-02 1988-07-06 Geistlich Soehne Ag Chemical compound
US5573771A (en) * 1988-08-19 1996-11-12 Osteomedical Limited Medicinal bone mineral products
GB8819755D0 (en) * 1988-08-19 1988-09-21 Geistlich Soehne Ag Chemical compound
US5290558A (en) * 1989-09-21 1994-03-01 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair
GB9400163D0 (en) 1994-01-06 1994-03-02 Geistlich Soehne Ag Membrane
GB9503492D0 (en) * 1995-02-22 1995-04-12 Ed Geistlich S Hne A G F R Che Chemical product
GB9721585D0 (en) * 1997-10-10 1997-12-10 Geistlich Soehne Ag Chemical product
CA2222626A1 (fr) * 1995-06-06 1996-12-12 Biocoll Laboratories, Inc. Materiaux osteogeniques modifies
US6352558B1 (en) * 1996-02-22 2002-03-05 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method for promoting regeneration of surface cartilage in a damage joint
US5899939A (en) * 1998-01-21 1999-05-04 Osteotech, Inc. Bone-derived implant for load-supporting applications
US6123731A (en) * 1998-02-06 2000-09-26 Osteotech, Inc. Osteoimplant and method for its manufacture
AU6499800A (en) * 1999-07-28 2001-02-19 Regeneration Technologies, Inc. Cartilage or bone matrix as a nucleic acid delivery vehicle

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JP4958344B2 (ja) 2012-06-20
US6576015B2 (en) 2003-06-10
JP2002078791A (ja) 2002-03-19
US20020013626A1 (en) 2002-01-31
CA2353240A1 (fr) 2002-01-19
NL1018560C2 (nl) 2003-08-19
NL1018560A1 (nl) 2002-01-22
PL348794A1 (en) 2002-01-28
CH695924A5 (de) 2006-10-31
ITMI20011468A0 (it) 2001-07-10
DK200101004A (da) 2002-01-20
RU2292858C2 (ru) 2007-02-10
ES2195731A1 (es) 2003-12-01
GB2367497B (en) 2004-02-25
GB0117623D0 (en) 2001-09-12
ITMI20011468A1 (it) 2003-01-10
DK177997B1 (da) 2015-02-23
CA2353240C (fr) 2011-09-27
DE10134514A1 (de) 2002-06-06
ES2195731B1 (es) 2005-04-01
FR2812553A1 (fr) 2002-02-08
GB2367497A (en) 2002-04-10

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