FR2802530B1 - Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2,4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant - Google Patents

Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2,4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant

Info

Publication number
FR2802530B1
FR2802530B1 FR9915935A FR9915935A FR2802530B1 FR 2802530 B1 FR2802530 B1 FR 2802530B1 FR 9915935 A FR9915935 A FR 9915935A FR 9915935 A FR9915935 A FR 9915935A FR 2802530 B1 FR2802530 B1 FR 2802530B1
Authority
FR
France
Prior art keywords
amino
triazole
phenyl
preparation
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9915935A
Other languages
English (en)
French (fr)
Other versions
FR2802530A1 (fr
Inventor
Michel Geslin
Daniele Gully
Jean Pierre Maffrand
Pierre Roger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9915935A priority Critical patent/FR2802530B1/fr
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Priority to BR0017023-2A priority patent/BR0017023A/pt
Priority to TR2004/01775T priority patent/TR200401775T4/xx
Priority to AU25259/01A priority patent/AU780711B2/en
Priority to HK03108164.0A priority patent/HK1055947B/xx
Priority to SI200030409T priority patent/SI1242389T1/xx
Priority to US10/149,499 priority patent/US6806282B2/en
Priority to MEP-121/08A priority patent/MEP12108A/xx
Priority to EEP200200331A priority patent/EE04778B1/xx
Priority to EP00988916A priority patent/EP1242389B1/fr
Priority to CZ20022099A priority patent/CZ302460B6/cs
Priority to PCT/FR2000/003536 priority patent/WO2001044207A2/fr
Priority to UA2002064623A priority patent/UA73333C2/uk
Priority to PL355811A priority patent/PL203819B1/pl
Priority to ES00988916T priority patent/ES2219436T3/es
Priority to MXPA02006033A priority patent/MXPA02006033A/es
Priority to EA200200523A priority patent/EA004957B1/ru
Priority to JP2001544697A priority patent/JP4146641B2/ja
Priority to YUP-439/02A priority patent/RS50289B/sr
Priority to CA2398772A priority patent/CA2398772C/fr
Priority to DE60010126T priority patent/DE60010126T2/de
Priority to KR1020027007736A priority patent/KR100705525B1/ko
Priority to IL15003700A priority patent/IL150037A0/xx
Priority to CO00095200A priority patent/CO5251379A1/es
Priority to SK850-2002A priority patent/SK285994B6/sk
Priority to TR2002/01600T priority patent/TR200201600T2/xx
Priority to HU0204080A priority patent/HUP0204080A3/hu
Priority to CNB00819078XA priority patent/CN1293061C/zh
Priority to PT00988916T priority patent/PT1242389E/pt
Priority to DK00988916T priority patent/DK1242389T3/da
Priority to AT00988916T priority patent/ATE264847T1/de
Priority to ARP000106666A priority patent/AR031837A1/es
Priority to TW089126997A priority patent/TWI289554B/zh
Publication of FR2802530A1 publication Critical patent/FR2802530A1/fr
Application granted granted Critical
Publication of FR2802530B1 publication Critical patent/FR2802530B1/fr
Priority to IL150037A priority patent/IL150037A/en
Priority to IS6402A priority patent/IS2315B/is
Priority to ZA200204422A priority patent/ZA200204422B/en
Priority to NO20022828A priority patent/NO20022828L/no
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR9915935A 1999-12-17 1999-12-17 Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2,4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant Expired - Fee Related FR2802530B1 (fr)

Priority Applications (37)

Application Number Priority Date Filing Date Title
FR9915935A FR2802530B1 (fr) 1999-12-17 1999-12-17 Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2,4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant
KR1020027007736A KR100705525B1 (ko) 1999-12-17 2000-12-14 치환되고 분지화된3-아미노-1-페닐-1ｈ-〔1,2,4〕트리아졸의 신규한 아미노유도체, 이의 제조 방법, 및 이를 포함하는 제약 조성물
AU25259/01A AU780711B2 (en) 1999-12-17 2000-12-14 Novel branched substituted amino derivatives of 3-amino-1-phenyl-H(1,2,4)triazol, methods for producing them and pharmaceutical compositions containing them
HK03108164.0A HK1055947B (en) 1999-12-17 2000-12-14 Novel branched substituted amino derivatives of 3-amino-1-phenyl-1h-[1,2,4] triazol, methods for producing them and pharmaceutical compositions containing them
SI200030409T SI1242389T1 (en) 1999-12-17 2000-12-14 Novel branched substituted amino derivatives of 3-amino-1-phenyl-1h(1,2,4)triazol, methods for producing them and pharmaceutical compositions containing them
US10/149,499 US6806282B2 (en) 1999-12-17 2000-12-14 Branched substituted amino derivatives of 3-amino-1-phenyl-1h-[1,2,4]triazol, methods for producing them and pharmaceutical compositions containing them
MEP-121/08A MEP12108A (en) 1999-12-17 2000-12-14 Novel branched substituted amino derivatives of 3-amino-1-phenyl-1h[1,2,4]triazol, methods for producing them and pharmaceutical compositions containing them
EEP200200331A EE04778B1 (et) 1999-12-17 2000-12-14 Hargnenud ahelaga asendatud 3-amino-1-fenüül-1H-[1,2,4]triasooli aminoderivaadid, nende valmistamismeetod ja neid sisaldavad farmatseutilised kompositsioonid
EP00988916A EP1242389B1 (fr) 1999-12-17 2000-12-14 Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2,4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant
CZ20022099A CZ302460B6 (cs) 1999-12-17 2000-12-14 Nové substituované aminoderiváty 3-amino-1-fenyl-1H-[1,2,4]triazolu, zpusob jejich prípravy a farmaceutické prostredky, které je obsahují
PCT/FR2000/003536 WO2001044207A2 (fr) 1999-12-17 2000-12-14 Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2 4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant
UA2002064623A UA73333C2 (en) 1999-12-17 2000-12-14 Branched substituted aminoderivatives of 3-amino-1-phenyl-1n-[1,2,4]triazole, a method for the preparation thereof (variants), pharmaceutical composition and medicament based thereon
PL355811A PL203819B1 (pl) 1999-12-17 2000-12-14 Aminopochodne 3-amino-1-fenylo-1H-[1,2,4]triazolu, sposób ich wytwarzania, środek farmaceutyczny, zastosowanie tych związków i sposób wytwarzania związków pośrednich
ES00988916T ES2219436T3 (es) 1999-12-17 2000-12-14 Nuevos derivados amino substituidos ramificados del 3-amino-1-fenil-1h (1,2,4)triazol, a los procedimientos para su preparacion, y a las composiciones farmaceuticas que los contienen.
MXPA02006033A MXPA02006033A (es) 1999-12-17 2000-12-14 Nuevos derivados amino substituidos ramificados de 3-amino-1-fenil-1h[1,2,4]triazol, procedimientos para su preparacion y composiciones farmaceuticas que los contienen.
EA200200523A EA004957B1 (ru) 1999-12-17 2000-12-14 Новые разветвленные замещенные аминопроизводные 3-амино-1-фенил-1h[1,2,4]триазола, способы их получения и содержащие их фармацевтические композиции
JP2001544697A JP4146641B2 (ja) 1999-12-17 2000-12-14 ３−アミノ−１−フェニル−１ｈ−［１，２，４］トリアゾールの新規な分岐状置換アミノ誘導体、それらの製造法およびそれらを含む医薬組成物
YUP-439/02A RS50289B (sr) 1999-12-17 2000-12-14 Novi razgranati supstituisani amino derivati od 3-amino-1- fenil-1h(1,2,4) triazola, postupak za njihovo dobijanje i farmaceutski preparati koji ih sadrže
BR0017023-2A BR0017023A (pt) 1999-12-17 2000-12-14 Derivados amino substituìdos ramificados do 3-amino-1-fenil-1h [1,2,4] triazol, processos para o respectivo preparo e composições farmacêuticas que os contêm
DE60010126T DE60010126T2 (de) 1999-12-17 2000-12-14 Verzweigte substituierte aminoderivate vom 3-amino-1-phenyl-1h(1,2,4)triazol, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen
CO00095200A CO5251379A1 (es) 1999-12-17 2000-12-14 Nuevos derivados aminosubstituidos ramificados de 3- amino-1-fenil-1h[1,2,4] triazol, procedimientos para su preparacion y composiciones farmaceuticas que los contienen
TR2004/01775T TR200401775T4 (tr) 1999-12-17 2000-12-14 3-Amino-1-Fenil-1H[1,2,4] triazol'ün dallanmış değiştirilmiş yeni amino türevleri, bunların imali için metot ve bunları içeren farmosötik (eczacılık) bileşimleri
IL15003700A IL150037A0 (en) 1999-12-17 2000-12-14 Novel branched substituted amino derivatives of 3-amino-1-phenyl-1h[1, 2, 4] triazol, methods for producing them and pharmaceutical compositions containing them
SK850-2002A SK285994B6 (sk) 1999-12-17 2000-12-14 Substituované aminoderiváty 3-amino-1-fenyl-1H-1,2,4-triazolu, spôsob ich prípravy a farmaceutické prostriedky, ktoré ich obsahujú
TR2002/01600T TR200201600T2 (tr) 1999-12-17 2000-12-14 Yer-alıma tabi tutulan, yeni, dallı 3-amino-1-fenil-1H-[1,2,4]triazol amino türevleri, bunların hazırlanması için prosesler ve bunları içeren farmasötik kompozisyonlar.
HU0204080A HUP0204080A3 (en) 1999-12-17 2000-12-14 Novel branched substituted amino derivatives of 3-amino-1-phenyl-1h[1,2,4]triazol, methods for producing them and pharmaceutical compositions containing them
CNB00819078XA CN1293061C (zh) 1999-12-17 2000-12-14 新的3－氨基－1－苯基－1h－[1,2,4]三唑的支链取代氨基衍生物、其制备方法和含有它们的药物组合物
PT00988916T PT1242389E (pt) 1999-12-17 2000-12-14 Novos derivados ramificados de 3-amino-1-fenil-h¬1,2,4|pirazole substituidos em amino processos para a sua preparacao e composicoes farmaceuticas que os contem
DK00988916T DK1242389T3 (da) 1999-12-17 2000-12-14 Nye forgrenede substituerede aminoderivater af 3-amino-1-phenyl-1H[1,2,4]triazol, fremgangsmåder til deres fremstilling og farmaceutiske præparater, der indeholder dem
AT00988916T ATE264847T1 (de) 1999-12-17 2000-12-14 Verzweigte substituierte aminoderivate vom 3- amino-1-phenyl-1h(1,2,4)triazol, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen
CA2398772A CA2398772C (fr) 1999-12-17 2000-12-14 Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2 4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant
ARP000106666A AR031837A1 (es) 1999-12-17 2000-12-15 Derivados amino substituidos ramificados de 3-amino-1-fenil-1h [1, 2, 4] triazol, su utilizacion, procedimientos para su preparacion y composiciones farmaceuticas que los contienen
TW089126997A TWI289554B (en) 1999-12-17 2001-01-29 Novel branched substituted amino derivatives of 3-amino-1-phenyl-H[1,2,4]triazole, process for their preparation and pharmaceutical compositions comprising them
IL150037A IL150037A (en) 1999-12-17 2002-05-04 Branched derivatives converted to the amino of 3-amino-1-phenyl-H1] 4,2,1 [H1-triazole, methods for their preparation and the pharmaceutical compositions containing them
IS6402A IS2315B (is) 1999-12-17 2002-05-28 Nýjar greinóttar setnar amínó afleiður af 3-amínó-1-fenýl-1H[1,2,4]tríasóli, aðferðir til framleiðslu á þeim og lyfjasamsetningar sem innihalda þær
ZA200204422A ZA200204422B (en) 1999-12-17 2002-06-03 Branched substituted amino derivatives of 3-amino-1-phenyl-1H(1,2,4)triazol, methods for producing them and pharmaceutical compositions containing them.
NO20022828A NO20022828L (no) 1999-12-17 2002-06-13 Nye forgrenede substituerte aminoderivater av 3-amino-1-fenyl- 1H[1,2,4]triazol, fremgangsmåter for deres fremstilling, ogfarmasöytiske preparater inneholdende disse

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9915935A FR2802530B1 (fr) 1999-12-17 1999-12-17 Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2,4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant

Publications (2)

Publication Number Publication Date
FR2802530A1 FR2802530A1 (fr) 2001-06-22
FR2802530B1 true FR2802530B1 (fr) 2002-02-22

Family

ID=9553380

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9915935A Expired - Fee Related FR2802530B1 (fr) 1999-12-17 1999-12-17 Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2,4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant

Country Status (33)

Country Link
US (1) US6806282B2 (enExample)
EP (1) EP1242389B1 (enExample)
JP (1) JP4146641B2 (enExample)
KR (1) KR100705525B1 (enExample)
CN (1) CN1293061C (enExample)
AR (1) AR031837A1 (enExample)
AT (1) ATE264847T1 (enExample)
AU (1) AU780711B2 (enExample)
BR (1) BR0017023A (enExample)
CA (1) CA2398772C (enExample)
CO (1) CO5251379A1 (enExample)
CZ (1) CZ302460B6 (enExample)
DE (1) DE60010126T2 (enExample)
DK (1) DK1242389T3 (enExample)
EA (1) EA004957B1 (enExample)
EE (1) EE04778B1 (enExample)
ES (1) ES2219436T3 (enExample)
FR (1) FR2802530B1 (enExample)
HU (1) HUP0204080A3 (enExample)
IL (2) IL150037A0 (enExample)
IS (1) IS2315B (enExample)
ME (1) MEP12108A (enExample)
MX (1) MXPA02006033A (enExample)
NO (1) NO20022828L (enExample)
PL (1) PL203819B1 (enExample)
PT (1) PT1242389E (enExample)
RS (1) RS50289B (enExample)
SK (1) SK285994B6 (enExample)
TR (2) TR200401775T4 (enExample)
TW (1) TWI289554B (enExample)
UA (1) UA73333C2 (enExample)
WO (1) WO2001044207A2 (enExample)
ZA (1) ZA200204422B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7226920B2 (en) * 2003-08-06 2007-06-05 Vertex Pharmaceuticals Inc. Aminotriazole compounds useful as inhibitors of protein kinases
JO3019B1 (ar) 2006-04-19 2016-09-05 Janssen Pharmaceutica Nv ثلاثي مستبدل 4،2،1-ثلاثي زولات
ES2424023T3 (es) 2007-10-18 2013-09-26 Janssen Pharmaceutica N.V. 1,2,4-triazoles trisustituidos
JO2784B1 (en) 2007-10-18 2014-03-15 شركة جانسين فارماسوتيكا ان. في 5,3,1 - Triazole substitute derivative
MY152486A (en) * 2008-03-19 2014-10-15 Janssen Pharmaceutica Nv Trisubstituted 1,2,4 - triazoles as nicotinic acetylcholine receptor modulators
US8779158B2 (en) 2008-05-09 2014-07-15 Janssen Pharmaceutica Nv Trisubstituted pyrazoles as acetylcholine receptor modulators
EP2629616A4 (en) * 2010-10-21 2014-03-26 Merck Sharp & Dohme SUBSTITUTED AMINO-TRIAZOLYL-PDE10-HEMMER
LT3096756T (lt) 2014-01-21 2024-08-26 Neurocrine Biosciences, Inc. Crf1 receptoriaus antagonistai, skirti įgimtos antinksčių hiperplazijos gydymui
CN104059027B (zh) * 2014-07-01 2015-10-28 河北大学 一类含1,2,4-三唑的(e)-甲氧基亚氨基苯乙酸甲酯类化合物及其制备方法和用途
FI3984523T3 (fi) 2018-12-07 2025-10-21 Neurocrine Biosciences Inc Crf1-reseptorin antagonisti, lääkeformulaatioita ja niiden kiinteitä muotoja synnynnäisen lisämunuaisten liikakasvun hoitoon
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