FR2534907B1 - Complexes diamine-platine, un procede pour leur preparation, un procede pour la preparation d'une composition medicinale utilisant un tel complexe diamine platine pour le traitement du cancer ainsi que la composition ainsi formee - Google Patents

Complexes diamine-platine, un procede pour leur preparation, un procede pour la preparation d'une composition medicinale utilisant un tel complexe diamine platine pour le traitement du cancer ainsi que la composition ainsi formee

Info

Publication number
FR2534907B1
FR2534907B1 FR8316715A FR8316715A FR2534907B1 FR 2534907 B1 FR2534907 B1 FR 2534907B1 FR 8316715 A FR8316715 A FR 8316715A FR 8316715 A FR8316715 A FR 8316715A FR 2534907 B1 FR2534907 B1 FR 2534907B1
Authority
FR
France
Prior art keywords
preparation
diamine
composition
cancer
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8316715A
Other languages
English (en)
French (fr)
Other versions
FR2534907A1 (fr
Inventor
Francois Verbeek
Jan Berg
Eric Jan Bulten
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Original Assignee
Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO filed Critical Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Publication of FR2534907A1 publication Critical patent/FR2534907A1/fr
Application granted granted Critical
Publication of FR2534907B1 publication Critical patent/FR2534907B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8316715A 1982-10-21 1983-10-20 Complexes diamine-platine, un procede pour leur preparation, un procede pour la preparation d'une composition medicinale utilisant un tel complexe diamine platine pour le traitement du cancer ainsi que la composition ainsi formee Expired FR2534907B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8204067A NL8204067A (nl) 1982-10-21 1982-10-21 Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiaminecomplex voor de behandeling van kanker, alsmede aldus verkregen gevormd geneesmiddel.

Publications (2)

Publication Number Publication Date
FR2534907A1 FR2534907A1 (fr) 1984-04-27
FR2534907B1 true FR2534907B1 (fr) 1988-08-19

Family

ID=19840444

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8316715A Expired FR2534907B1 (fr) 1982-10-21 1983-10-20 Complexes diamine-platine, un procede pour leur preparation, un procede pour la preparation d'une composition medicinale utilisant un tel complexe diamine platine pour le traitement du cancer ainsi que la composition ainsi formee

Country Status (28)

Country Link
JP (1) JPS5993091A (show.php)
KR (1) KR910002536B1 (show.php)
AT (1) AT390610B (show.php)
AU (1) AU562964B2 (show.php)
BE (1) BE898058A (show.php)
CA (1) CA1229618A (show.php)
CH (1) CH658244A5 (show.php)
CS (1) CS242888B2 (show.php)
DD (1) DD217522A5 (show.php)
DE (1) DE3337333A1 (show.php)
DK (2) DK483083A (show.php)
ES (1) ES526670A0 (show.php)
FI (1) FI76351C (show.php)
FR (1) FR2534907B1 (show.php)
GB (1) GB2128615B (show.php)
GR (1) GR79652B (show.php)
HU (1) HU188035B (show.php)
IE (1) IE56124B1 (show.php)
IT (1) IT1169858B (show.php)
LU (1) LU85054A1 (show.php)
NL (1) NL8204067A (show.php)
NO (1) NO171276C (show.php)
NZ (1) NZ206018A (show.php)
PH (1) PH24077A (show.php)
PT (1) PT77542B (show.php)
SE (1) SE8305783L (show.php)
YU (1) YU43554B (show.php)
ZA (1) ZA837857B (show.php)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4786725A (en) * 1982-06-28 1988-11-22 Engelhard Corporation Solubilized platinum (II) complexes
US4661516A (en) * 1983-06-20 1987-04-28 Research Corporation Diaminocyclohexane platinum complexes
US4758588A (en) * 1983-06-20 1988-07-19 Research Corporation Technologies Diaminocyclohexane platinum complexes
EP0169645A1 (en) * 1984-06-27 1986-01-29 Johnson Matthey Public Limited Company Platinum co-ordination compounds
DE3432320A1 (de) * 1984-09-03 1986-03-13 Behringwerke Ag, 3550 Marburg Cis-platin-komplexe mit einem pentaerythritderivat als liganden, verfahren zu ihrer herstellung und diese verbindungen enthaltendes pharmazeutisches mittel
HU193809B (en) * 1984-09-12 1987-12-28 Chugai Pharmaceutical Co Ltd Process for producing new platinum complexes
US4737589A (en) * 1985-08-27 1988-04-12 Nippon Kayaku Kabushiki Kaisha Platinum Complexes
US4760157A (en) * 1986-01-31 1988-07-26 American Cyanamid Company (2,2,-bis(aminomethyl)-1,3-propanediol-N,N')platinum complexes
US4880790A (en) * 1986-01-31 1989-11-14 American Cyanamid Company (Gem-heterocyclodimethanamine-N,N')platinum complexes
DE3630497A1 (de) * 1986-09-08 1988-03-10 Behringwerke Ag Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
ATE53217T1 (de) * 1986-10-03 1990-06-15 Asta Pharma Ag Diamin-platin (ii)-komplexverbindungen mit einem hydroxylierten 2-phenyl-indolring.
JPS63203692A (ja) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd 新規白金錯体
AT390065B (de) * 1987-10-08 1990-03-12 Behringwerke Ag Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
NL8802150A (nl) * 1988-08-31 1990-03-16 Tno Platina-(ii)-diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat deze verbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
NL8802149A (nl) * 1988-08-31 1990-03-16 Tno Platina-(iv)diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat ten minste een platinaverbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
CN102924528B (zh) * 2012-10-29 2015-04-15 东南大学 抗肿瘤二价铂配合物以及该配合物和其配体的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115418A (en) * 1976-09-02 1978-09-19 Government Of The United States Of America 1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
US4206226A (en) * 1977-08-29 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Use of 4-carboxy-phthalato-(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof in alleviating L1210 murine leukemia
NL7807334A (nl) * 1978-07-06 1980-01-08 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel.
NL189358C (nl) * 1978-07-06 1993-03-16 Tno Werkwijze voor het bereiden van een geneesmiddel voor de behandeling van kanker, alsmede een van een 1,3-alkaandiamine afgeleid platina-diamminecomplex.
AU538863B2 (en) * 1980-05-27 1984-08-30 Bristol-Myers Company Platinum complex salts have anti-tumor property
US4322362A (en) * 1980-07-28 1982-03-30 Bristol-Myers Company Salts of 2-hydroxymalonate platinum complexes

Also Published As

Publication number Publication date
FI76351B (fi) 1988-06-30
NL8204067A (nl) 1984-05-16
AU2027583A (en) 1984-05-03
ATA373083A (de) 1989-11-15
HU188035B (en) 1986-03-28
JPH0244479B2 (show.php) 1990-10-04
JPS5993091A (ja) 1984-05-29
CA1229618A (en) 1987-11-24
DE3337333A1 (de) 1984-04-26
PT77542A (en) 1983-11-01
DK75592D0 (da) 1992-06-09
AU562964B2 (en) 1987-06-25
FR2534907A1 (fr) 1984-04-27
IE832459L (en) 1984-04-21
FI76351C (fi) 1988-10-10
PT77542B (en) 1986-02-12
PH24077A (en) 1990-03-05
ZA837857B (en) 1984-06-27
ES8406498A1 (es) 1984-07-01
SE8305783L (sv) 1984-04-22
KR910002536B1 (ko) 1991-04-23
GB2128615A (en) 1984-05-02
ES526670A0 (es) 1984-07-01
SE8305783D0 (sv) 1983-10-20
NO171276C (no) 1993-02-17
IT1169858B (it) 1987-06-03
NO833825L (no) 1984-04-24
DK483083D0 (da) 1983-10-20
FI833842L (fi) 1984-04-22
DD217522A5 (de) 1985-01-16
KR840006492A (ko) 1984-11-30
GB8328084D0 (en) 1983-11-23
CH658244A5 (de) 1986-10-31
BE898058A (nl) 1984-04-24
CS242888B2 (en) 1986-05-15
DK75592A (da) 1992-06-09
YU210783A (en) 1986-08-31
LU85054A1 (show.php) 1984-03-22
IT8323359A0 (it) 1983-10-19
GR79652B (show.php) 1984-10-31
CS775283A2 (en) 1985-08-15
IE56124B1 (en) 1991-04-24
GB2128615B (en) 1986-07-16
FI833842A0 (fi) 1983-10-20
NO171276B (no) 1992-11-09
NZ206018A (en) 1986-02-21
DK483083A (da) 1984-04-22
YU43554B (en) 1989-08-31
AT390610B (de) 1990-06-11

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