FR2440946B2 - - Google Patents
Info
- Publication number
- FR2440946B2 FR2440946B2 FR7831458A FR7831458A FR2440946B2 FR 2440946 B2 FR2440946 B2 FR 2440946B2 FR 7831458 A FR7831458 A FR 7831458A FR 7831458 A FR7831458 A FR 7831458A FR 2440946 B2 FR2440946 B2 FR 2440946B2
- Authority
- FR
- France
- Prior art keywords
- derivatives
- nervous system
- central nervous
- substituted heterocyclic
- new substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940054066 benzamide antipsychotics Drugs 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- -1 heterocyclic benzamides Chemical class 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/28—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups having unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (55)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7831458A FR2440946A2 (fr) | 1978-01-20 | 1978-11-07 | Nouveaux benzamides heterocycliques substitues, leurs procedes de preparation et leur application comme modificateurs du comportement |
ES476757A ES476757A1 (es) | 1978-01-20 | 1979-01-11 | Un procedimiento de preparacion de benzamidas heterociclicassustituidas. |
AR275135A AR221355A1 (es) | 1978-01-20 | 1979-01-11 | Procedimiento para la preparacion de derivados de pirrolidinil y pirrolidinilmetil-benzamidas |
MC791354A MC1231A1 (fr) | 1978-01-20 | 1979-01-11 | Nouveaux benzamides heterocycliques substitues,leurs procedes de preparation et leur application comme modificateurs du comportement |
IL56413A IL56413A (en) | 1978-01-20 | 1979-01-11 | Substituted heterocyclic benzamides,their preparation and pharmaceutical compositions containing them |
PT69069A PT69069A (fr) | 1978-01-20 | 1979-01-12 | Procede de preparation de benzamides heterocycliques substitues |
DE19792901170 DE2901170A1 (de) | 1978-01-20 | 1979-01-13 | Substituierte heterocyclische benzamide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
NZ189381A NZ189381A (en) | 1978-01-20 | 1979-01-15 | Substituted heterocyclic benzamides and pharmaceutical compositions |
AU43374/79A AU520746B2 (en) | 1978-01-20 | 1979-01-15 | Substituted pyrrolidino benzamides |
BG042076A BG48335A3 (bg) | 1978-01-20 | 1979-01-15 | Метод за получаване на заместени хетероциклични бензамиди |
GR58091A GR64398B (en) | 1978-01-20 | 1979-01-15 | Methods for the preparation of new substituted of heterocyclic benzamides |
BG043504A BG48336A3 (bg) | 1978-01-20 | 1979-01-15 | Метод за получаване на заместени хетероциклични бензамиди |
LU80793A LU80793A1 (fr) | 1978-01-20 | 1979-01-16 | Nouveaux benzamides heterocycliques substitues,leurs procedes de preparation et leur application comme modificateurs du comportement |
YU105/79A YU41608B (en) | 1978-01-20 | 1979-01-17 | Process for obtaining new derivatives of substituted benzamides |
CY1202A CY1202A (en) | 1978-01-20 | 1979-01-17 | Substituted heterocyclic benzamides methods of preparing them compositions containing them and their use as behaviour modifiers |
GB7901688A GB2013662B (en) | 1978-01-20 | 1979-01-17 | Substituted heterocyclic benzamides methods of preparing them compositions containing them and their use es behaviour modifiers |
BE1/9242A BE873522A (fr) | 1978-01-20 | 1979-01-17 | Nouveaux benzamides heterocycliques substitues, leurs procedes de preparation et leur application comme modificateurs du comportement |
SE7900419A SE449862B (sv) | 1978-01-20 | 1979-01-17 | Substituerade, heterocykliska bensamider, sett att framstella dessa och en faramakologisk komposition |
EG28/79A EG13764A (en) | 1978-01-20 | 1979-01-17 | New substituted heterocyclic benzamides methods of preparing them and their application as behavior modifiers |
IN46/CAL/79A IN150618B (en, 2012) | 1978-01-20 | 1979-01-17 | |
GB8119940A GB2083459B (en) | 1978-01-20 | 1979-01-17 | New substituted heterocyclic benzamides and their production |
NO790179A NO153530C (no) | 1978-01-20 | 1979-01-18 | Analogifremgangsm¨te for fremstilling av terapeutisk aktiv e substituerte heterocykliske benzamider. |
RO79103351A RO80716A (ro) | 1978-01-20 | 1979-01-18 | Procedeu de preparare a unor pirolidinilbenzamide |
CH50979A CH639369A5 (fr) | 1978-01-20 | 1979-01-18 | Benzamides heterocycliques substitues et leurs procedes de preparation. |
IT47707/79A IT1164821B (it) | 1978-01-20 | 1979-01-18 | Benzammidi eterocicliche sostituite procedimento per la loro produzione e loro impiego come modificatori di comportamento |
DK021079A DK157008C (da) | 1978-01-20 | 1979-01-18 | Analogifremgangsmaade til fremstilling af n-pyrrolidinyl- eller n-pyrrolidinylmethylsubstituerede benzamider samt mellemprodukter til brug ved fremstillingen |
RO7996327A RO76554A (ro) | 1978-01-20 | 1979-01-18 | Procedeu de preparare a unor pirolidinilbenzamide |
DD79210558A DD141521A5 (de) | 1978-01-20 | 1979-01-19 | Verfahren zur herstellung neuer heterozyklischer benzamide |
CA319,968A CA1133477A (en) | 1978-01-20 | 1979-01-19 | Novel substituted heterocyclic benzamides, process for their preparation and use as behaviour modifiers |
JP548479A JPS54138553A (en) | 1978-01-20 | 1979-01-19 | Novel heterocyclic benzamide*its manufacture and psychotropic drug |
SU792712702A SU1158040A3 (ru) | 1978-01-20 | 1979-01-19 | Способ получени гетероциклических бензамидов или их солей |
PL1979212898A PL117195B1 (en) | 1978-01-20 | 1979-01-19 | Method of manufacture of novel derivatives of pyrrolidinyl-or pyrrolidinylalkylbenzamidepirolidinilalkilbenzamida |
CS8380A CS241039B2 (en) | 1978-01-20 | 1979-01-19 | Method of new n-(2-(or 3)pyrrolidinyle(or pyrrolidinylmethyl)((-benzamides production,substituted in positions 2,3,4,5,6 |
NL7900455A NL7900455A (nl) | 1978-01-20 | 1979-01-19 | Nieuwe gesubstitueerde heterocyclische benzamiden, werkwijze voor de bereiding daarvan en toepassing als gedragsbeinvloedende stoffen. |
OA56713A OA06153A (fr) | 1978-01-20 | 1979-01-19 | Nouveaux benzamides hétérocycliques substitués, leurs procédés de préparation et leur application comme modificateurs du comportement. |
AT0039779A AT377254B (de) | 1978-01-20 | 1979-01-19 | Verfahren zur herstellung neuer substituierter pyrrolidine und deren salzen |
HU79SO1242A HU177902B (en) | 1978-01-20 | 1979-01-19 | Process for preparing new substituted heterocyclic benzamides |
MX7911207U MX7622E (es) | 1978-01-20 | 1979-01-19 | Procedimiento para la preparacion de benamidas heterociclicas substituidas |
FI790181A FI69833C (fi) | 1978-01-20 | 1979-01-19 | Foerfarande foer framstaellning av terapeutiskt anvaendbara sustituerade heterocykliska bensamider |
MX797670U MX6192E (es) | 1978-01-20 | 1979-01-19 | Procedimiento para la preparacion de benzamidas heterociclicas substituidas |
CS79444A CS241016B2 (en) | 1978-01-20 | 1979-01-19 | Method of new n-(2-(or)pyrrolidinylmethyl)-benzamides production substituted in positions 2,3,4,5,6 |
IE91/79A IE48208B1 (en) | 1978-01-20 | 1979-01-30 | New substituted heterocyclic benzamides,methods of preparing them,compositions containing them,and their use as behaviour modifiers |
IE2021/81A IE48209B1 (en) | 1978-01-20 | 1979-01-30 | Novel substituted heterocyclic benzamides and their production |
ES477783A ES477783A1 (es) | 1978-01-20 | 1979-02-16 | Un procedimiento de preparacion de benzamidas heterocicli- cas sustituidas. |
AR281712A AR221428A1 (es) | 1978-01-20 | 1980-07-10 | Procedimiento para la preparacion de derivados de pirrolidinil-y de pirrolidinilmetil-benzamidas |
NZ196409A NZ196409A (en) | 1978-01-20 | 1981-03-04 | Dihalophenyl substituted benzmides |
IL64928A IL64928A0 (en) | 1978-01-20 | 1982-02-03 | Substituted benzamides and their preparation |
IN453/CAL/82A IN151650B (en, 2012) | 1978-11-07 | 1982-04-22 | |
YU2685/82A YU43809B (en) | 1978-01-20 | 1982-12-03 | Process for obtaining new substituted benzamides |
CH289083A CH641154A5 (fr) | 1978-01-20 | 1983-05-26 | Benzamides heterocycliques substitues. |
AT0301483A AT377979B (de) | 1978-01-20 | 1983-08-24 | Verfahren zur herstellung neuer substituierter pyrrolidine sowie von deren saeureadditionssalzen |
HK122/84A HK12284A (en) | 1978-01-20 | 1984-02-16 | New substituted heterocyclic benzamides,methods of preparing them,compositions containing them,and their use as behaviour modifiers |
US06/769,796 US4673686A (en) | 1978-01-20 | 1985-08-26 | New substituted heterocyclic benzamides, methods of preparing them and their application as behavior modifiers |
US06/858,906 US4816471A (en) | 1978-01-20 | 1986-04-30 | Substituted heterocyclic benzamides, methods of preparing them and their application as anti-emetics |
SE8604394A SE463972B (sv) | 1978-01-20 | 1986-10-16 | Substituerade bensamider foer anvaendning som mellanfoereningar till framstaellning av terapeutiskt anvaendbara, substituerade, heterocykliska bensamider |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7801633A FR2424909A1 (fr) | 1978-01-20 | 1978-01-20 | Nouveaux derives d'ortho-anisamides utiles comme medicaments modificateurs du comportement, et leurs procedes de preparation |
FR7831458A FR2440946A2 (fr) | 1978-01-20 | 1978-11-07 | Nouveaux benzamides heterocycliques substitues, leurs procedes de preparation et leur application comme modificateurs du comportement |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2440946A2 FR2440946A2 (fr) | 1980-06-06 |
FR2440946B2 true FR2440946B2 (en, 2012) | 1981-07-17 |
Family
ID=26220412
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7831458A Granted FR2440946A2 (fr) | 1978-01-20 | 1978-11-07 | Nouveaux benzamides heterocycliques substitues, leurs procedes de preparation et leur application comme modificateurs du comportement |
Country Status (39)
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8101536L (sv) * | 1981-03-11 | 1982-09-12 | Astra Laekemedel Ab | Bensamid-derivat |
SE8205135D0 (sv) * | 1982-09-09 | 1982-09-09 | Astra Laekemedel Ab | Benzamido-derivatives |
CH656126A5 (de) * | 1983-08-18 | 1986-06-13 | Ciba Geigy Ag | Durch 2-propynyloxygruppen substituierte phthalsaeureanhydride. |
US5240957A (en) * | 1984-01-31 | 1993-08-31 | Astra Lakemedel Akteibolag | Oxysalicylamido derivatives |
SE8400478D0 (sv) * | 1984-01-31 | 1984-01-31 | Astra Laekemedel Ab | Oxysalicylamido derivatives |
FR2574795B1 (fr) * | 1984-12-18 | 1987-11-20 | Ile De France | Nouveau procede industriel de synthese du n-((1'-allyl 2'-pyrrolidinyl) methyl) 2-methoxy 4,5-azimido benzamide |
FR2586018B1 (fr) * | 1985-08-12 | 1988-03-25 | Ile De France | Nouveau benzodioxepanne, son procede de synthese et ses applications en therapeutique |
US4772459A (en) * | 1986-09-09 | 1988-09-20 | Erbamont, Inc. | Method for controlling emesis caused by chemotherapeutic agents and antiemetic agents useful therein |
US5154913A (en) * | 1987-11-19 | 1992-10-13 | Vanderbilt University | Radioiodinated benzamines method of their use as radioimaging agents |
EP0320630A1 (en) * | 1987-11-19 | 1989-06-21 | The Vanderbilt University | Enantiometric iodobenzamides |
HU208005B (en) * | 1990-02-19 | 1993-07-28 | Kyorin Seiyaku Kk | Process for producing optically active 8-methoxy-quinolone-carboxylic acid derivatives and pharmaceutical compositions containing them |
FR2678266A1 (fr) * | 1991-06-28 | 1992-12-31 | Delagrange Laboratoires | Nouveaux derives de 2-hydroxy 4-amino 5-ethylsulfonyl benzamide utiles comme anxiolytiques. |
US6517811B2 (en) | 1993-05-06 | 2003-02-11 | Research Corporation Technologies, Inc. | Compounds for cancer imaging and therapy |
US5911970A (en) * | 1993-05-06 | 1999-06-15 | Research Corporation Technologies, Inc. | Methods for cancer imaging and therapy using benzamine compounds |
US5993777A (en) * | 1993-05-06 | 1999-11-30 | Research Corporation Technologies, Inc. | Benzamide compounds for cancer imaging and therapy |
CA2139503A1 (en) * | 1993-05-06 | 1994-11-24 | Christy S. John | Compounds for cancer imaging and therapy |
CN103450058B (zh) * | 2013-09-18 | 2015-10-14 | 广安凯特医药化工有限公司 | 一种氨磺必利酸的制备方法 |
CN105503666A (zh) * | 2015-12-30 | 2016-04-20 | 苏州诚和医药化学有限公司 | 一种便捷合成2-甲氧基-5-氨磺酰基苯甲酸甲酯的方法 |
Family Cites Families (27)
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US3342826A (en) * | 1964-01-13 | 1967-09-19 | Ile De France | Heterocyclic aminoalkyl benzamides |
FR6787M (en, 2012) * | 1967-08-17 | 1969-03-17 | ||
US3891671A (en) * | 1968-08-01 | 1975-06-24 | Ile De France | N-(2-pyrrolidyl or piperidyl alkyl)-4-hydroxy benzamides |
US3959477A (en) * | 1968-08-01 | 1976-05-25 | Societe D'etudes Scientifiques Et Industrielles De L'ile-De-France | Methods of protection against emesis in mammals by administration of a heterocyclic benzamide |
US3577440A (en) * | 1968-12-23 | 1971-05-04 | Robins Co Inc A H | 1-substituted-3-amido-pyrrolidines |
GB1364231A (en) * | 1968-12-23 | 1974-08-21 | Robins Co Inc A H | N-/1-substituted-3-pyrrolidinyl/benzamides and thiobenzamides |
FR2097031A1 (en) * | 1970-07-29 | 1972-03-03 | Berri Balzac | 2-aminoethoxyethyl-6,6-dimethyl nor pinane derivs - local anaesthetics spasmolytics and anticholinergics |
GB1392194A (en) * | 1971-09-23 | 1975-04-30 | Wyeth John & Brother Ltd | Pyrrolidine derivatives |
US3966957A (en) * | 1972-04-03 | 1976-06-29 | A. H. Robins Company, Incorporated | Method for controlling emesis with N-(1-substituted-3-pyrrolidinyl)benzamides and thiobenzamides |
US4279822A (en) * | 1972-04-03 | 1981-07-21 | A. H. Robins Company, Inc. | N-(1-Substituted-3-pyrrolidinyl)benzamides |
US3862139A (en) * | 1972-06-23 | 1975-01-21 | Delmar Chem | Heterocyclic benzamide compounds |
US4048321A (en) * | 1973-12-14 | 1977-09-13 | Science Union Et Cie | Disubstituted azabicycloalkanes |
CH605793A5 (fr) * | 1974-03-05 | 1978-10-13 | Soc Et Scient Et Ind | Procédé de préparation de nouveaux N-(1benzylpyrrollidinil 2-alkyl) benzamides substitués |
US4158060A (en) * | 1974-12-18 | 1979-06-12 | Synthelabo | 2-Methoxy-benzamide derivatives |
US4172143A (en) * | 1974-12-18 | 1979-10-23 | Synthelabo | 2-Methoxy-benzamide derivatives |
IE42210B1 (en) * | 1974-12-18 | 1980-06-18 | Synthelabo | 2-methoxy-benzamide derivatives |
US4039672A (en) * | 1975-01-11 | 1977-08-02 | Societe D'etudes Scientifiques Et Industrielles De L'ile-De-France | N-(1'-allypyrrolidinyl 2'-methyl) 2-methoxy 4,5-azimido benzamide and its pharmaceutically acceptable salts |
US4197243A (en) * | 1975-04-02 | 1980-04-08 | Yamanouchi Pharmaceutical Co., Ltd. | N-1-Benzyl-3-pyrrolidinyl-4-dimethylamino benzamide derivatives |
GB1520584A (en) * | 1975-04-02 | 1978-08-09 | Yamanouchi Pharma Co Ltd | 2 - alkoxy - 5 substituted benzamide derivatives and their use in pharmaceutical compositions |
CH614709A5 (en, 2012) * | 1975-09-25 | 1979-12-14 | Ciba Geigy Ag | |
JPS5248661A (en) * | 1975-10-14 | 1977-04-18 | Synthelabo | 22methoxyybenzamide derivatives |
NZ186175A (en) * | 1977-01-27 | 1980-03-05 | Shionogi & Co | Meta-sulphonamidobenzamide derivatives |
FR2415099A1 (fr) * | 1978-01-20 | 1979-08-17 | Ile De France | Nouveaux derives de 4-amino-5-alkylsulfonyl ortho-anisamides, leurs procedes de preparation et leur application comme psychotropes |
IL61642A0 (en) * | 1979-12-20 | 1981-01-30 | Beecham Group Ltd | Aniline derivatives,their preparation and pharmalceutical compositions containing them |
IL61972A0 (en) * | 1980-01-30 | 1981-02-27 | Beecham Group Ltd | Azabicyclic compounds,their preparation and pharmaceutical compositions containing them |
US4352802A (en) * | 1980-06-10 | 1982-10-05 | Beecham Group Limited | Bicyclo[3.3.1]nonyl-benzamide |
FR2493848B2 (fr) * | 1980-11-07 | 1986-05-16 | Delalande Sa | Nouveaux derives des nor-tropane et granatane, leur procede de preparation et leur application en therapeutique |
-
1978
- 1978-11-07 FR FR7831458A patent/FR2440946A2/fr active Granted
-
1979
- 1979-01-11 IL IL56413A patent/IL56413A/xx unknown
- 1979-01-11 AR AR275135A patent/AR221355A1/es active
- 1979-01-11 ES ES476757A patent/ES476757A1/es not_active Expired
- 1979-01-11 MC MC791354A patent/MC1231A1/xx unknown
- 1979-01-12 PT PT69069A patent/PT69069A/pt unknown
- 1979-01-13 DE DE19792901170 patent/DE2901170A1/de active Granted
- 1979-01-15 GR GR58091A patent/GR64398B/el unknown
- 1979-01-15 NZ NZ189381A patent/NZ189381A/en unknown
- 1979-01-15 BG BG042076A patent/BG48335A3/xx unknown
- 1979-01-15 AU AU43374/79A patent/AU520746B2/en not_active Ceased
- 1979-01-15 BG BG043504A patent/BG48336A3/xx unknown
- 1979-01-16 LU LU80793A patent/LU80793A1/xx unknown
- 1979-01-17 CY CY1202A patent/CY1202A/en unknown
- 1979-01-17 IN IN46/CAL/79A patent/IN150618B/en unknown
- 1979-01-17 YU YU105/79A patent/YU41608B/xx unknown
- 1979-01-17 GB GB8119940A patent/GB2083459B/en not_active Expired
- 1979-01-17 GB GB7901688A patent/GB2013662B/en not_active Expired
- 1979-01-17 BE BE1/9242A patent/BE873522A/xx not_active IP Right Cessation
- 1979-01-17 EG EG28/79A patent/EG13764A/xx active
- 1979-01-17 SE SE7900419A patent/SE449862B/sv not_active IP Right Cessation
- 1979-01-18 IT IT47707/79A patent/IT1164821B/it active
- 1979-01-18 CH CH50979A patent/CH639369A5/fr not_active IP Right Cessation
- 1979-01-18 DK DK021079A patent/DK157008C/da not_active IP Right Cessation
- 1979-01-18 RO RO79103351A patent/RO80716A/ro unknown
- 1979-01-18 RO RO7996327A patent/RO76554A/ro unknown
- 1979-01-18 NO NO790179A patent/NO153530C/no unknown
- 1979-01-19 NL NL7900455A patent/NL7900455A/xx not_active Application Discontinuation
- 1979-01-19 SU SU792712702A patent/SU1158040A3/ru active
- 1979-01-19 CS CS79444A patent/CS241016B2/cs unknown
- 1979-01-19 OA OA56713A patent/OA06153A/xx unknown
- 1979-01-19 MX MX797670U patent/MX6192E/es unknown
- 1979-01-19 PL PL1979212898A patent/PL117195B1/pl unknown
- 1979-01-19 FI FI790181A patent/FI69833C/fi not_active IP Right Cessation
- 1979-01-19 JP JP548479A patent/JPS54138553A/ja active Granted
- 1979-01-19 HU HU79SO1242A patent/HU177902B/hu not_active IP Right Cessation
- 1979-01-19 DD DD79210558A patent/DD141521A5/de unknown
- 1979-01-19 CS CS8380A patent/CS241039B2/cs unknown
- 1979-01-19 AT AT0039779A patent/AT377254B/de not_active IP Right Cessation
- 1979-01-19 CA CA319,968A patent/CA1133477A/en not_active Expired
- 1979-01-19 MX MX7911207U patent/MX7622E/es unknown
- 1979-01-30 IE IE91/79A patent/IE48208B1/en not_active IP Right Cessation
- 1979-01-30 IE IE2021/81A patent/IE48209B1/en not_active IP Right Cessation
- 1979-02-16 ES ES477783A patent/ES477783A1/es not_active Expired
-
1980
- 1980-07-10 AR AR281712A patent/AR221428A1/es active
-
1981
- 1981-03-04 NZ NZ196409A patent/NZ196409A/xx unknown
-
1982
- 1982-02-03 IL IL64928A patent/IL64928A0/xx not_active IP Right Cessation
- 1982-12-03 YU YU2685/82A patent/YU43809B/xx unknown
-
1983
- 1983-05-26 CH CH289083A patent/CH641154A5/fr not_active IP Right Cessation
- 1983-08-24 AT AT0301483A patent/AT377979B/de not_active IP Right Cessation
-
1984
- 1984-02-16 HK HK122/84A patent/HK12284A/xx unknown
-
1985
- 1985-08-26 US US06/769,796 patent/US4673686A/en not_active Expired - Fee Related
-
1986
- 1986-04-30 US US06/858,906 patent/US4816471A/en not_active Expired - Fee Related
- 1986-10-16 SE SE8604394A patent/SE463972B/sv not_active IP Right Cessation
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