AR221355A1 - Procedimiento para la preparacion de derivados de pirrolidinil y pirrolidinilmetil-benzamidas - Google Patents

Procedimiento para la preparacion de derivados de pirrolidinil y pirrolidinilmetil-benzamidas

Info

Publication number
AR221355A1
AR221355A1 AR275135A AR27513579A AR221355A1 AR 221355 A1 AR221355 A1 AR 221355A1 AR 275135 A AR275135 A AR 275135A AR 27513579 A AR27513579 A AR 27513579A AR 221355 A1 AR221355 A1 AR 221355A1
Authority
AR
Argentina
Prior art keywords
pirrolidinil
pirrolidinilmetil
benzamidas
derivatives
procedure
Prior art date
Application number
AR275135A
Other languages
English (en)
Original Assignee
Ile De France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR7801633A priority Critical patent/FR2424909B1/fr
Priority to FR7831458A priority patent/FR2440946B2/fr
Application filed by Ile De France filed Critical Ile De France
Application granted granted Critical
Publication of AR221355A1 publication Critical patent/AR221355A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14Nitrogen atoms not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/28Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups having unsaturation outside the aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S514/00Drug, bio-affecting and body treating compositions
    • Y10S514/872Emesis, motion sickness-nausea
AR275135A 1978-01-20 1979-01-11 Procedimiento para la preparacion de derivados de pirrolidinil y pirrolidinilmetil-benzamidas AR221355A1 (es)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR7801633A FR2424909B1 (es) 1978-01-20 1978-01-20
FR7831458A FR2440946B2 (es) 1978-01-20 1978-11-07

Publications (1)

Publication Number Publication Date
AR221355A1 true AR221355A1 (es) 1981-01-30

Family

ID=26220412

Family Applications (2)

Application Number Title Priority Date Filing Date
AR275135A AR221355A1 (es) 1978-01-20 1979-01-11 Procedimiento para la preparacion de derivados de pirrolidinil y pirrolidinilmetil-benzamidas
AR281712A AR221428A1 (es) 1978-01-20 1980-07-10 Procedimiento para la preparacion de derivados de pirrolidinil-y de pirrolidinilmetil-benzamidas

Family Applications After (1)

Application Number Title Priority Date Filing Date
AR281712A AR221428A1 (es) 1978-01-20 1980-07-10 Procedimiento para la preparacion de derivados de pirrolidinil-y de pirrolidinilmetil-benzamidas

Country Status (39)

Country Link
US (2) US4673686A (es)
JP (1) JPS6343386B2 (es)
AR (2) AR221355A1 (es)
AT (2) AT377254B (es)
AU (1) AU520746B2 (es)
BE (1) BE873522A (es)
BG (2) BG48336A3 (es)
CA (1) CA1133477A (es)
CH (2) CH639369A5 (es)
CS (2) CS241016B2 (es)
CY (1) CY1202A (es)
DD (1) DD141521A5 (es)
DE (1) DE2901170C2 (es)
DK (1) DK157008C (es)
EG (1) EG13764A (es)
ES (2) ES476757A1 (es)
FI (1) FI69833C (es)
FR (1) FR2440946B2 (es)
GB (2) GB2013662B (es)
GR (1) GR64398B (es)
HK (1) HK12284A (es)
HU (1) HU177902B (es)
IE (2) IE48209B1 (es)
IL (2) IL56413A (es)
IN (1) IN150618B (es)
IT (1) IT1164821B (es)
LU (1) LU80793A1 (es)
MC (1) MC1231A1 (es)
MX (2) MX6192E (es)
NL (1) NL7900455A (es)
NO (1) NO153530C (es)
NZ (2) NZ189381A (es)
OA (1) OA06153A (es)
PL (1) PL117195B1 (es)
PT (1) PT69069A (es)
RO (2) RO80716A (es)
SE (2) SE449862B (es)
SU (1) SU1158040A3 (es)
YU (2) YU41608B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8101536L (sv) * 1981-03-11 1982-09-12 Astra Laekemedel Ab Bensamid-derivat
SE8205135D0 (sv) * 1982-09-09 1982-09-09 Astra Laekemedel Ab Benzamido-derivatives
CH656126A5 (de) * 1983-08-18 1986-06-13 Ciba Geigy Ag Durch 2-propynyloxygruppen substituierte phthalsaeureanhydride.
US5240957A (en) * 1984-01-31 1993-08-31 Astra Lakemedel Akteibolag Oxysalicylamido derivatives
SE8400478D0 (sv) * 1984-01-31 1984-01-31 Astra Laekemedel Ab Oxysalicylamido derivatives
FR2574795B1 (fr) * 1984-12-18 1987-11-20 Ile De France Nouveau procede industriel de synthese du n-((1'-allyl 2'-pyrrolidinyl) methyl) 2-methoxy 4,5-azimido benzamide
FR2586018B1 (fr) * 1985-08-12 1988-03-25 Ile De France Nouveau benzodioxepanne, son procede de synthese et ses applications en therapeutique
US4772459A (en) * 1986-09-09 1988-09-20 Erbamont, Inc. Method for controlling emesis caused by chemotherapeutic agents and antiemetic agents useful therein
US5154913A (en) * 1987-11-19 1992-10-13 Vanderbilt University Radioiodinated benzamines method of their use as radioimaging agents
EP0320630A1 (en) * 1987-11-19 1989-06-21 The Vanderbilt University Enantiometric iodobenzamides
HU208005B (en) * 1990-02-19 1993-07-28 Kyorin Seiyaku Kk Process for producing optically active 8-methoxy-quinolone-carboxylic acid derivatives and pharmaceutical compositions containing them
FR2678266A1 (fr) * 1991-06-28 1992-12-31 Delagrange Laboratoires Nouveaux derives de 2-hydroxy 4-amino 5-ethylsulfonyl benzamide utiles comme anxiolytiques.
US5993777A (en) * 1993-05-06 1999-11-30 Research Corporation Technologies, Inc. Benzamide compounds for cancer imaging and therapy
US6517811B2 (en) 1993-05-06 2003-02-11 Research Corporation Technologies, Inc. Compounds for cancer imaging and therapy
US5911970A (en) * 1993-05-06 1999-06-15 Research Corporation Technologies, Inc. Methods for cancer imaging and therapy using benzamine compounds
WO1994026314A1 (en) * 1993-05-06 1994-11-24 John Christy S Compounds for cancer imaging and therapy
CN103450058B (zh) * 2013-09-18 2015-10-14 广安凯特医药化工有限公司 一种氨磺必利酸的制备方法
CN105503666A (zh) * 2015-12-30 2016-04-20 苏州诚和医药化学有限公司 一种便捷合成2-甲氧基-5-氨磺酰基苯甲酸甲酯的方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR4879M (es) * 1964-01-13
FR6787M (es) * 1967-08-17 1969-03-17
US3891671A (en) * 1968-08-01 1975-06-24 Ile De France N-(2-pyrrolidyl or piperidyl alkyl)-4-hydroxy benzamides
US3959477A (en) * 1968-08-01 1976-05-25 Societe D'etudes Scientifiques Et Industrielles De L'ile-De-France Methods of protection against emesis in mammals by administration of a heterocyclic benzamide
US3577440A (en) * 1968-12-23 1971-05-04 Robins Co Inc A H 1-substituted-3-amido-pyrrolidines
GB1364231A (en) * 1968-12-23 1974-08-21 Robins Co Inc A H N-/1-substituted-3-pyrrolidinyl/benzamides and thiobenzamides
FR2097031B1 (es) * 1970-07-29 1973-08-10 Berri Balzac
GB1392194A (en) * 1971-09-23 1975-04-30 Wyeth John & Brother Ltd Pyrrolidine derivatives
US4279822A (en) * 1972-04-03 1981-07-21 A. H. Robins Company, Inc. N-(1-Substituted-3-pyrrolidinyl)benzamides
US3966957A (en) * 1972-04-03 1976-06-29 A. H. Robins Company, Incorporated Method for controlling emesis with N-(1-substituted-3-pyrrolidinyl)benzamides and thiobenzamides
US3862139A (en) * 1972-06-23 1975-01-21 Delmar Chem Heterocyclic benzamide compounds
US4048321A (en) * 1973-12-14 1977-09-13 Science Union Et Cie Disubstituted azabicycloalkanes
CH605793A5 (es) * 1974-03-05 1978-10-13 Ile De France
CA1039731A (en) * 1974-12-18 1978-10-03 Synthelabo Process for preparing new 2-methoxy-benzamide derivatives
US4172143A (en) * 1974-12-18 1979-10-23 Synthelabo 2-Methoxy-benzamide derivatives
US4158060A (en) * 1974-12-18 1979-06-12 Synthelabo 2-Methoxy-benzamide derivatives
US4039672A (en) * 1975-01-11 1977-08-02 Societe D'etudes Scientifiques Et Industrielles De L'ile-De-France N-(1'-allypyrrolidinyl 2'-methyl) 2-methoxy 4,5-azimido benzamide and its pharmaceutically acceptable salts
US4197243A (en) * 1975-04-02 1980-04-08 Yamanouchi Pharmaceutical Co., Ltd. N-1-Benzyl-3-pyrrolidinyl-4-dimethylamino benzamide derivatives
GB1520584A (en) * 1975-04-02 1978-08-09 Yamanouchi Pharma Co Ltd 2 - alkoxy - 5 substituted benzamide derivatives and their use in pharmaceutical compositions
CH614709A5 (es) * 1975-09-25 1979-12-14 Ciba Geigy Ag
JPS5549574B2 (es) * 1975-10-14 1980-12-12
NZ186175A (en) * 1977-01-27 1980-03-05 Shionogi & Co Meta-sulphonamidobenzamide derivatives
FR2415099B1 (es) * 1978-01-20 1981-02-20 Ile De France
IL61642D0 (en) * 1979-12-20 1981-01-30 Beecham Group Ltd Aniline derivatives,their preparation and pharmalceutical compositions containing them
IL61972D0 (en) * 1980-01-30 1981-02-27 Beecham Group Ltd Azabicyclic compounds,their preparation and pharmaceutical compositions containing them
US4352802A (en) * 1980-06-10 1982-10-05 Beecham Group Limited Bicyclo[3.3.1]nonyl-benzamide
FR2493848B2 (fr) * 1980-11-07 1986-05-16 Delalande Sa Nouveaux derives des nor-tropane et granatane, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
MX6192E (es) 1984-12-13
HU177902B (en) 1982-01-28
FR2440946B2 (es) 1981-07-17
BG48335A3 (en) 1991-01-15
DK157008C (da) 1990-03-26
IE48208B1 (en) 1984-10-31
IN150618B (es) 1982-11-13
EG13764A (en) 1982-06-30
GR64398B (en) 1980-03-21
OA06153A (fr) 1981-06-30
DE2901170A1 (de) 1979-07-26
GB2083459A (en) 1982-03-24
CH641154A5 (fr) 1984-02-15
FI790181A (fi) 1979-07-21
CS44479A2 (en) 1985-06-13
CS8083A2 (en) 1985-06-13
ES476757A1 (es) 1979-05-16
ATA39779A (de) 1983-10-15
AU4337479A (en) 1979-07-26
YU10579A (en) 1983-02-28
ATA301483A (de) 1984-10-15
JPS54138553A (en) 1979-10-27
IL56413A (en) 1982-11-30
NO153530C (no) 1986-04-09
CS241016B2 (en) 1986-03-13
AT377979B (de) 1985-05-28
IT7947707D0 (it) 1979-01-18
HK12284A (en) 1984-02-24
SE449862B (sv) 1987-05-25
FR2440946A2 (fr) 1980-06-06
FI69833C (fi) 1986-05-26
US4673686A (en) 1987-06-16
US4816471A (en) 1989-03-28
IE48209B1 (en) 1984-10-31
GB2013662B (en) 1982-10-06
CH639369A5 (fr) 1983-11-15
SE7900419L (sv) 1979-07-21
DK157008B (da) 1989-10-30
AR221428A1 (es) 1981-01-30
IE790091L (en) 1979-07-20
YU268582A (en) 1987-10-31
FI69833B (fi) 1985-12-31
SE8604394L (sv) 1986-10-16
YU41608B (en) 1987-12-31
RO80716A (ro) 1982-12-06
LU80793A1 (fr) 1979-09-07
IL56413D0 (en) 1979-03-12
RO76554A (ro) 1981-04-30
SU1158040A3 (ru) 1985-05-23
IT1164821B (it) 1987-04-15
DK21079A (da) 1979-07-21
AT377254B (de) 1985-02-25
AU520746B2 (en) 1982-02-25
NZ189381A (en) 1982-03-09
BG48336A3 (en) 1991-01-15
CS241039B2 (en) 1986-03-13
BE873522A (fr) 1979-07-17
PT69069A (fr) 1979-02-01
NO790179L (no) 1979-07-23
PL117195B1 (en) 1981-07-31
PL212898A1 (es) 1980-03-24
CA1133477A (en) 1982-10-12
IL64928D0 (en) 1982-04-30
SE8604394D0 (sv) 1986-10-16
YU43809B (en) 1989-12-31
DD141521A5 (de) 1980-05-07
SE463972B (sv) 1991-02-18
NL7900455A (nl) 1979-07-24
NZ196409A (en) 1982-03-09
GB2013662A (en) 1979-08-15
JPS6343386B2 (es) 1988-08-30
MC1231A1 (fr) 1979-10-26
CY1202A (en) 1983-12-31
NO153530B (no) 1985-12-30
GB2083459B (en) 1982-12-15
MX7622E (es) 1990-03-27
DE2901170C2 (es) 1992-09-17
ES477783A1 (es) 1979-10-16

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