FR2409743A1 - Sonde de ph a fibres optiques - Google Patents

Sonde de ph a fibres optiques

Info

Publication number
FR2409743A1
FR2409743A1 FR7833324A FR7833324A FR2409743A1 FR 2409743 A1 FR2409743 A1 FR 2409743A1 FR 7833324 A FR7833324 A FR 7833324A FR 7833324 A FR7833324 A FR 7833324A FR 2409743 A1 FR2409743 A1 FR 2409743A1
Authority
FR
France
Prior art keywords
probe
membrane
passage
optical fiber
hollow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7833324A
Other languages
English (en)
Other versions
FR2409743B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
USA
Original Assignee
USA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by USA filed Critical USA
Publication of FR2409743A1 publication Critical patent/FR2409743A1/fr
Application granted granted Critical
Publication of FR2409743B1 publication Critical patent/FR2409743B1/fr
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G01N21/80—Indicating pH value
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring pH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
    • G01N31/221—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators for investigating pH value

Abstract

LA PRESENTE INVENTION CONCERNE UNE SONDE DE PH A FIBRES OPTIQUES. CETTE SONDE 10 PEUT ETRE IMPLANTEE DANS UN TISSU POUR DES ETUDES PHYSIOLOGIQUES. ELLE COMPREND UNE MEMBRANE PERMEABLE AUX IONS 11 AYANT LA FORME D'UN CYLINDRE CREUX ALLONGE, UNE PAIRE DE FIBRES OPTIQUES 12, 13, LES EXTREMITES DISTALES DES FIBRES ETANT SITUEES DANS LA MEMBRANE CREUSE, ET UN MATERIAU 14 CONTENANT UN COLORANT SENSIBLE AU PH SITUE DANS LA MEMBRANE CREUSE, CETTE MEMBRANE AYANT DES PORES D'UNE DIMENSION SUFFISAMMENT GRANDE POUR PERMETTRE LE PASSAGE DES IONS HYDROGENE TOUT EN EMPECHANT LE PASSAGE DU MATERIAU CONTENANT LE COLORANT. APPLICATION A LA DETERMINATION IN VIVO DU PH SANGUIN.
FR7833324A 1977-11-28 1978-11-24 Sonde de ph a fibres optiques Granted FR2409743A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/855,384 US4200110A (en) 1977-11-28 1977-11-28 Fiber optic pH probe

Publications (2)

Publication Number Publication Date
FR2409743A1 true FR2409743A1 (fr) 1979-06-22
FR2409743B1 FR2409743B1 (fr) 1984-01-06

Family

ID=25321113

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7833324A Granted FR2409743A1 (fr) 1977-11-28 1978-11-24 Sonde de ph a fibres optiques

Country Status (7)

Country Link
US (1) US4200110A (fr)
JP (1) JPS5485588A (fr)
CA (1) CA1121242A (fr)
DE (1) DE2851138A1 (fr)
FR (1) FR2409743A1 (fr)
GB (1) GB2009394B (fr)
NL (1) NL7811372A (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2461255A1 (fr) * 1979-07-10 1981-01-30 Hellige Gmbh Procede et dispositif pour la determination photometrique transcutanee de la concentration de constituants du sang
EP0036017A1 (fr) * 1979-09-20 1981-09-23 Richard G Buckles Appareil d'analyses.
EP0073558A2 (fr) * 1981-08-25 1983-03-09 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce Capteur à fibres optiques pour la mesure de pH de tissus
EP0080411A1 (fr) * 1981-11-20 1983-06-01 Societe D'etudes Scientifiques Et Industrielles De L'ile-De-France Indicateur coloré pour la détermination de l'hypoacidité de la muqueuse gastrique au cours de la gastroscopie
EP0321924A2 (fr) * 1987-12-23 1989-06-28 Willi Möller AG Matériau polymérique pouvant former une couche stable de protéine à sa surface après contact avec un matériau contenant des protéines, et utilisation de ce matériau polymérique

Families Citing this family (271)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399099A (en) * 1979-09-20 1983-08-16 Buckles Richard G Optical fiber apparatus for quantitative analysis
DE3001669A1 (de) * 1980-01-18 1981-08-06 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Anordnung zur optischen messung von physikalischen groessen und stoffkonzentrationen
US4799756A (en) * 1980-10-06 1989-01-24 The Regents Of The University Of California Remote multi-position information gathering system and method
US4626693A (en) * 1980-10-06 1986-12-02 The Regents Of The University Of California Remote multi-position information gathering system and method
US4577109A (en) * 1980-10-06 1986-03-18 Regents Of The University Of California Remote multi-position information gathering system and method
JPS624837Y2 (fr) * 1980-10-30 1987-02-04
EP0061884A1 (fr) * 1981-03-30 1982-10-06 Imperial Chemical Industries Plc Capteur en fibre optique
EP0074976A1 (fr) * 1981-03-31 1983-03-30 Commonwealth Scientific And Industrial Research Organisation Application de sondes a fibres optiques
GB2103786A (en) * 1981-08-14 1983-02-23 Ici Plc Fibre optic sensor
US4476870A (en) * 1982-03-30 1984-10-16 The United States Of America As Represented By The Department Of Health And Human Services Fiber optic PO.sbsb.2 probe
DE3213183A1 (de) * 1982-04-08 1983-10-20 Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Anordnung zur optischen messung physikalischer groessen
US4658825A (en) * 1982-09-24 1987-04-21 International Biomedics, Inc. Spiral probe for simultaneous electrical and chemical monitoring of a fetus
JPS5980230A (ja) * 1982-09-24 1984-05-09 アボット・ラボラトリーズ 心電図用電極とｐＨプロ−ブとの結合体
US4557900A (en) * 1982-09-28 1985-12-10 Cardiovascular Devices, Inc. Optical sensor with beads
US4599901A (en) * 1982-09-30 1986-07-15 University Of California Pressure-sensitive optrode
US4784811A (en) * 1982-09-30 1988-11-15 The Regents Of The University Of California Method of constructing improved pressure-sensitive optrode
AT380957B (de) * 1982-12-06 1986-08-11 List Hans Sensorelement fuer fluoreszenzoptische messungen, sowie verfahren zu seiner herstellung
DE3343636A1 (de) * 1982-12-07 1984-06-07 AVL AG, 8201 Schaffhausen Sensorelement fuer fluoreszenzoptische messung sowie verfahren zu seiner herstellung
US4548907A (en) * 1983-09-14 1985-10-22 Allied Corporation Fluorescent fluid determination method and apparatus
SE8305704D0 (sv) * 1983-10-18 1983-10-18 Leo Ab Cuvette
US4622974A (en) * 1984-03-07 1986-11-18 University Of Tennessee Research Corporation Apparatus and method for in-vivo measurements of chemical concentrations
US4945230A (en) * 1984-07-06 1990-07-31 Metricor, Inc. Optical measuring device using a spectral modulation sensor having an optically resonant structure
US4678904A (en) * 1984-07-06 1987-07-07 Technology Dynamics, Inc. Optical measuring device using a spectral modulation sensor having an optically resonant structure
US4803049A (en) * 1984-12-12 1989-02-07 The Regents Of The University Of California pH-sensitive optrode
US4768886A (en) * 1984-12-26 1988-09-06 The Regents Of The University Of California Method and apparatus for simultaneously measuring temperature and pressure
DE8516344U1 (de) * 1985-02-14 1986-07-31 Proton AG, Zug Optischer Sensor für eine Messwertgebereinrichtung zur Überwachung biologischer und/oder chemischer Reaktionen
WO1986005589A1 (fr) * 1985-03-20 1986-09-25 Monash University Senseur chimique a fibre optique
US4666672A (en) * 1985-04-08 1987-05-19 University Of California Optrode for sensing hydrocarbons
US5354825A (en) * 1985-04-08 1994-10-11 Klainer Stanley M Surface-bound fluorescent polymers and related methods of synthesis and use
US4801655A (en) * 1985-06-21 1989-01-31 Gould, Inc. Fiber optic pH sensor having low drift rate
US4682895A (en) * 1985-08-06 1987-07-28 Texas A&M University Fiber optic probe for quantification of colorimetric reactions
US4929561A (en) * 1985-08-08 1990-05-29 Regents Of The University Of California Absorption-emission optrode and methods of use thereof
US4706677A (en) * 1985-09-23 1987-11-17 Spectramed, Inc. Multiple sensor bundle
US4758298A (en) * 1985-09-23 1988-07-19 Spectramed, Inc. Method for forming multiple sensor bundle
US4632119A (en) * 1985-10-23 1986-12-30 University Of Health Sciences/The Chicago Medical School Ambulatory esophageal pH monitor
US5019350A (en) * 1986-02-13 1991-05-28 Pfizer Hospital Products, Inc. Fluorescent polymers
US4710623A (en) * 1986-02-27 1987-12-01 Eli Lilly And Company Optical fiber catheter with fiber-contained reactive element
US4798738A (en) * 1986-10-10 1989-01-17 Cardiovascular Devices, Inc. Micro sensor
US4824789B1 (en) * 1986-10-10 1996-08-13 Minnesota Mining & Mfg Gas sensor
US5006314A (en) * 1986-04-18 1991-04-09 Minnesota Mining And Manufacturing Company Sensor and method for sensing the concentration of a component in a medium
JPS62263448A (ja) * 1986-05-30 1987-11-16 ザ・レ−ゲンツ・オブ・ザ・ユニバ−シテイ・オブ・カリフオルニヤ ｐＨ監視装置
AU7316287A (en) * 1986-06-02 1987-12-03 Vincent L. Vaillancourt Naso-gastric intubation system having a ph indicator
US4822127A (en) * 1986-06-16 1989-04-18 Shiley Incorporated Multi-channel optical transmission system
US4927222A (en) * 1986-06-16 1990-05-22 Shiley Incorporated Dual optical fiber device
US4854321A (en) * 1986-06-18 1989-08-08 Medex, Inc. Integrated optic system for monitoring blood gases
US4929562A (en) * 1986-08-20 1990-05-29 The Regents Of The University Of California Method and apparatus for detecting gem-polyhalogenated hydrocarbons
US4820490A (en) * 1986-09-11 1989-04-11 Miles Inc. Device and method for chemical analysis of fluids with a reagent coated light source
US4760250A (en) * 1986-09-29 1988-07-26 Spectramed, Inc. Optoelectronics system for measuring environmental properties having plural feedback detectors
US5120510A (en) * 1986-10-10 1992-06-09 Minnesota Mining And Manufacturing Company Sensor and method for sensing the concentration of a component in a medium
US4867919A (en) * 1986-10-10 1989-09-19 Minnesota Mining And Manufacturing Company Method of making a gas sensor
US4886338A (en) * 1986-10-10 1989-12-12 Minnesota Mining And Manufacturing Company Optical fiber event sensor
WO1988005533A1 (fr) * 1987-01-16 1988-07-28 Kelsius, Inc. Amplification de signaux provenant de fibres optiques
US4989606A (en) * 1987-01-30 1991-02-05 Minnesota Mining And Manufactoring Company Intravascular blood gas sensing system
US4951669A (en) * 1987-01-30 1990-08-28 Minnesota Mining And Manufacturing Company Blood parameter measurement system
US4934369A (en) * 1987-01-30 1990-06-19 Minnesota Mining And Manufacturing Company Intravascular blood parameter measurement system
US4830013A (en) * 1987-01-30 1989-05-16 Minnesota Mining And Manufacturing Co. Intravascular blood parameter measurement system
US5048525A (en) * 1987-01-30 1991-09-17 Minnesota Mining And Manufacturing Company Blood parameter measurement system with compliant element
US5462052A (en) * 1987-01-30 1995-10-31 Minnesota Mining And Manufacturing Co. Apparatus and method for use in measuring a compositional parameter of blood
US5093266A (en) * 1987-02-06 1992-03-03 Shiley Inc. Sensor system
US4833091A (en) * 1987-02-06 1989-05-23 Shiley Incorporated Sensor system
DE3889537T2 (de) * 1987-02-20 1994-08-25 Terumo Corp Sonde zum messen der konzentration von gelöstem gas.
US4834496A (en) * 1987-05-22 1989-05-30 American Telephone And Telegraph Company, At&T Bell Laboratories Optical fiber sensors for chemical detection
US4816130A (en) * 1987-07-02 1989-03-28 Becton, Dickinson And Company Blood electrolyte sensors including crosslinked polyetherurethane membranes
AT388248B (de) * 1987-07-20 1989-05-26 Avl Verbrennungskraft Messtech Deckschicht, vorzugsweise zur probenseitigen anbringung an optischen ionensensoren
US4785814A (en) * 1987-08-11 1988-11-22 Cordis Corporation Optical probe for measuring pH and oxygen in blood and employing a composite membrane
US4851195A (en) * 1987-08-17 1989-07-25 Pfizer Hospital Products Group, Inc. Carbon dioxide sensor
US4842783A (en) * 1987-09-03 1989-06-27 Cordis Corporation Method of producing fiber optic chemical sensors incorporating photocrosslinked polymer gels
EP0312293A3 (fr) * 1987-10-16 1990-03-14 O.C.T. Optical Chemical Technologies Limited Dispositif capteur pour analyse
US5037615A (en) * 1987-10-30 1991-08-06 Cordis Corporation Tethered pair fluorescence energy transfer indicators, chemical sensors, and method of making such sensors
JPH01182437A (ja) * 1988-01-18 1989-07-20 Ig Tech Res Inc 防水敷目材
US4971447A (en) * 1988-03-17 1990-11-20 Siemens Aktiengesellschaft Method for measuring concentration of chemical substances
US5127077A (en) * 1988-07-25 1992-06-30 Abbott Laboratories Fiber-optic physiological probes
US4925268A (en) * 1988-07-25 1990-05-15 Abbott Laboratories Fiber-optic physiological probes
US5000901A (en) * 1988-07-25 1991-03-19 Abbott Laboratories Fiber-optic physiological probes
US4885077A (en) * 1988-11-17 1989-12-05 Becton, Dickinson And Company Composite membrane, method for its preparation and electrolyte sensor including same
US4889407A (en) * 1988-12-02 1989-12-26 Biomedical Sensors Limited Optical waveguide sensor and method of making same
US5039492A (en) * 1989-01-27 1991-08-13 Metricor, Inc. Optical pH and gas concentration sensor
US4892383A (en) * 1989-02-17 1990-01-09 Fiberchem Inc. Reservoir fiber optic chemical sensors
US4906249A (en) * 1989-02-23 1990-03-06 Medtronic, Inc. Terpolymer composition with bound indicator dye for fiber optic probe
US5343861A (en) * 1989-04-10 1994-09-06 Herman Wesley K Disposable tonometer cover with fluorescein dye
US5166073A (en) * 1989-05-05 1992-11-24 The Dow Chemical Company Miniaturized sensor for ionizing radiation
US5139023A (en) * 1989-06-02 1992-08-18 Theratech Inc. Apparatus and method for noninvasive blood glucose monitoring
DE3923921A1 (de) * 1989-07-19 1991-01-24 Biotechnolog Forschung Gmbh Optischer biosensor
FR2650076B1 (fr) * 1989-07-20 1991-10-04 Commissariat Energie Atomique Capteur chimique actif a fibre optique et son procede de fabrication
US5085216A (en) * 1989-07-25 1992-02-04 Henley Jr Robert L Nasogastric/nasointestinal enteral feeding tube and method for avoiding tracheobronchial misplacement
US5176881A (en) * 1989-08-11 1993-01-05 The University Of Tennessee Research Corporation Fiber optic-based regenerable biosensor
US5182353A (en) * 1989-08-16 1993-01-26 Puritan-Bennett Corporation Method for bonding an analyte-sensitive dye compound to an addition-cure silicone
US5330718A (en) * 1989-08-16 1994-07-19 Puritan-Bennett Corporation Sensor element and method for making the same
EP0413499A3 (en) * 1989-08-16 1991-07-24 Puritan-Bennett Corporation Sensor element and method for making the same
US5434084A (en) * 1989-09-06 1995-07-18 The Washington Research Foundation Flow optrode having separate reaction and detection chambers
US5132057A (en) * 1989-10-11 1992-07-21 Medex, Inc. Method of making an optical fiber probe
US5056520A (en) * 1989-10-11 1991-10-15 Medex, Inc. Probe for blood gas sensing
JPH04109151A (ja) * 1990-08-29 1992-04-10 Susumu Sato センサー
JP2646141B2 (ja) * 1989-11-24 1997-08-25 佐藤 進 異常検出装置
US5218212A (en) * 1989-11-24 1993-06-08 Mitsubishi Denki Kabushiki Kaisha Device for optically detecting a chemical change in fluid
US5244810A (en) * 1990-01-12 1993-09-14 Gottlieb Amos J Analytical method
US5236667A (en) * 1990-03-14 1993-08-17 University Of Pittsburgh Surface modification of plastic optical fibers
US5077078A (en) * 1990-03-14 1991-12-31 University Of Pittsburgh Of The Commonwealth System Of Higher Education Surface modification of plastic optical fibers
US5063178A (en) * 1990-03-19 1991-11-05 Medex, Inc. Freeze-dried blood gas sensor
US5175016A (en) * 1990-03-20 1992-12-29 Minnesota Mining And Manufacturing Company Method for making gas sensing element
US5115811A (en) * 1990-04-30 1992-05-26 Medtronic, Inc. Temperature measurement and compensation in a fiber-optic sensor
US5124130A (en) * 1990-05-22 1992-06-23 Optex Biomedical, Inc. Optical probe
WO1991018549A1 (fr) * 1990-05-29 1991-12-12 Yue Samuel K Appareil a sonde foetale
US5271073A (en) * 1990-08-10 1993-12-14 Puritan-Bennett Corporation Optical fiber sensor and method of manufacture
US5201755A (en) * 1990-09-11 1993-04-13 Datascope Investment Corp. Method and apparatus for early detection of leakage and failure of a balloon membrane of a balloon catheter
CA2053449A1 (fr) * 1990-10-16 1992-04-17 Henry K. Hui Microdetecteur de ph a fibre optique et sa methode de fabrication
US5275160A (en) * 1991-01-14 1994-01-04 The General Hospital Corporation Probes for radiance dosimetry
US5212099A (en) * 1991-01-18 1993-05-18 Eastman Kodak Company Method and apparatus for optically measuring concentration of an analyte
US5119463A (en) * 1991-04-09 1992-06-02 Abbott Laboratories Compound optical probe employing single optical waveguide
WO1993007483A1 (fr) * 1991-09-30 1993-04-15 Merck Patent Gmbh MEMBRANE DETECTRICE POUR L'AFFICHAGE DU pH D'UN ECHANTILLON, SA FABRICATION ET SON UTILISATION
US5853669A (en) * 1991-09-30 1998-12-29 Merck Patent Gesellschaft Mit Beschrankter Haftung Sensor membrane for indicating the PH of a sample, the fabrication and use thereof
US5650331A (en) * 1991-10-03 1997-07-22 The United States Of America As Represented By The United States Department Of Energy Optical high acidity sensor
US5335305A (en) * 1991-12-19 1994-08-02 Optex Biomedical, Inc. Optical sensor for fluid parameters
US5318029A (en) * 1992-02-11 1994-06-07 Oasis Medical, Inc. Tonometer shield
US5280130A (en) * 1992-05-22 1994-01-18 Biomedical Sensors, Ltd. Assembly of a tube and a part and apparatus and method of manufacture
US5266271A (en) * 1992-05-22 1993-11-30 Puritan-Bennett Corporation Microsensor copolymer and method of manufacture
US5246109A (en) * 1992-05-22 1993-09-21 Biomedical Sensors, Ltd. Package for an active medical device
US5335658A (en) * 1992-06-29 1994-08-09 Minnesota Mining And Manufacturing Company Intravascular blood parameter sensing system
AT399402B (de) * 1992-07-09 1995-05-26 Avl Verbrennungskraft Messtech Sensormembran eines optischen sensors zur bestimmung eines physikalischen oder chemischen parameters einer probe
WO1994010553A1 (fr) * 1992-10-23 1994-05-11 Optex Biomedical, Inc. Sonde a fibres optiques de mesure des parametres d'un fluide
IL107396A (en) * 1992-11-09 1997-02-18 Boehringer Mannheim Gmbh Method and apparatus for analytical determination of glucose in a biological matrix
DE4314835A1 (de) * 1993-05-05 1994-11-10 Boehringer Mannheim Gmbh Verfahren und Vorrichtung zur Analyse von Glucose in einer biologischen Matrix
US5326531A (en) * 1992-12-11 1994-07-05 Puritan-Bennett Corporation CO2 sensor using a hydrophilic polyurethane matrix and process for manufacturing
US5583051A (en) * 1993-02-03 1996-12-10 The United States Of America As Represented By The Department Of Energy Use of a fiber optic probe for organic species determination
KR0180315B1 (ko) * 1993-06-30 1999-03-20 알렌 제이. 스피겔 환자혈액중의 다수 변수들의 생체내 측정을 위한 다-변수 카테터
US5582184A (en) 1993-10-13 1996-12-10 Integ Incorporated Interstitial fluid collection and constituent measurement
US5579774A (en) * 1994-03-07 1996-12-03 Camino Neurocare, Inc. Method and apparatus for monitoring local cerebral physiology
DE4414103A1 (de) * 1994-04-22 1995-10-26 Reinmueller Johannes Medizinische Implantate aus Formkörpern
US6615066B2 (en) 1994-05-26 2003-09-02 Imec Vzw Gastrointestinal probe
DE69500723T2 (de) * 1994-05-26 1998-03-19 Imec Inter Uni Micro Electr Magen-Darm-Sonde
DE4445668C2 (de) * 1994-12-21 1997-05-15 Euroferm Gmbh I Gr Vorrichtung zur Messung des Partialdruckes von in Flüssigkeiten gelösten Gasen in Anlagen zur Durchführung von biotechnologischen oder lebensmitteltechnologischen Prozessen
DE19515821C2 (de) * 1995-04-29 1997-10-09 Univ Schiller Jena Verfahren zur VIS-spektroskopischen photometrischen Schnellbestimmung der Konzentration nichtionischer Tenside in wäßrigen Reinigungsmedien ohne Abtrennung weiterer Probenbestandteile mit pH-Indikatorfarbstoffen und Testkit zur Durchführung des Verfahrens
DE19530183A1 (de) * 1995-08-17 1997-02-20 Macherey Nagel & Co Chem Photometrische pH-Messung
US5654539A (en) * 1995-08-17 1997-08-05 Vasamedics L.L.C. Laser doppler optical sensor for use on a monitoring probe
US6058321A (en) * 1995-09-07 2000-05-02 Swayze; Claude R. Instrument for continuously monitoring fetal heart rate and intermittently monitoring fetal blood pH and method of use
US6624882B2 (en) * 1995-09-08 2003-09-23 Integ, Inc. Methods of sampling body fluid
US6614522B1 (en) * 1995-09-08 2003-09-02 Integ, Inc. Body fluid sampler
AU7015096A (en) * 1995-09-08 1997-04-09 Integ, Inc. Body fluid sampler
US5879367A (en) * 1995-09-08 1999-03-09 Integ, Inc. Enhanced interstitial fluid collection
US6615071B1 (en) 1995-09-20 2003-09-02 Board Of Regents, The University Of Texas System Method and apparatus for detecting vulnerable atherosclerotic plaque
US6763261B2 (en) 1995-09-20 2004-07-13 Board Of Regents, The University Of Texas System Method and apparatus for detecting vulnerable atherosclerotic plaque
DE69622764T2 (de) * 1995-09-20 2003-04-24 Texas Heart Inst Houston yNZEIGE VON THERMISCHEN UNSTETIGKEITEN AN GEFÄSSWÄNDEN
IT1280954B1 (it) * 1995-10-05 1998-02-11 Sorin Biomedica Cardio Spa Procedimento e sistema per rilevare parametri chimico-fisici.
US20020077564A1 (en) * 1996-07-29 2002-06-20 Farallon Medsystems, Inc. Thermography catheter
US5906636A (en) 1996-09-20 1999-05-25 Texas Heart Institute Heat treatment of inflamed tissue
US7603166B2 (en) 1996-09-20 2009-10-13 Board Of Regents University Of Texas System Method and apparatus for detection of vulnerable atherosclerotic plaque
US6274086B1 (en) 1996-12-16 2001-08-14 The Trustees Of The University Of Pennsylvania Apparatus for non-invasive imaging oxygen distribution in multi-dimensions
US5830138A (en) 1996-12-16 1998-11-03 Trustees Of The University Of Pennsylvania Intravascular catheter probe for clinical oxygen, pH and CO2 measurement
US6327410B1 (en) 1997-03-14 2001-12-04 The Trustees Of Tufts College Target analyte sensors utilizing Microspheres
US20030027126A1 (en) * 1997-03-14 2003-02-06 Walt David R. Methods for detecting target analytes and enzymatic reactions
US6023540A (en) 1997-03-14 2000-02-08 Trustees Of Tufts College Fiber optic sensor with encoded microspheres
US7622294B2 (en) * 1997-03-14 2009-11-24 Trustees Of Tufts College Methods for detecting target analytes and enzymatic reactions
US6406845B1 (en) 1997-05-05 2002-06-18 Trustees Of Tuft College Fiber optic biosensor for selectively detecting oligonucleotide species in a mixed fluid sample
US6048359A (en) * 1997-08-25 2000-04-11 Advanced Photodynamic Technologies, Inc. Spatial orientation and light sources and method of using same for medical diagnosis and photodynamic therapy
US7348181B2 (en) 1997-10-06 2008-03-25 Trustees Of Tufts College Self-encoding sensor with microspheres
US7115884B1 (en) 1997-10-06 2006-10-03 Trustees Of Tufts College Self-encoding fiber optic sensor
US6210910B1 (en) 1998-03-02 2001-04-03 Trustees Of Tufts College Optical fiber biosensor array comprising cell populations confined to microcavities
CA2329783A1 (fr) 1998-05-13 1999-11-18 Yellow Springs Optical Sensor Co. Pll. Systeme et procede de detection chimique optique
WO1999067641A2 (fr) 1998-06-24 1999-12-29 Illumina, Inc. Decodage de detecteurs matriciels a microspheres
DE19844781C2 (de) * 1998-09-30 2001-05-23 Titv Greiz Faseroptische pH-Sonde zur Bestimmung des pH-Wertes auf einer Oberfläche, insbesondere von Textilien, in Gegenwart einer flüssigen Phase
US6429027B1 (en) 1998-12-28 2002-08-06 Illumina, Inc. Composite arrays utilizing microspheres
US7510841B2 (en) 1998-12-28 2009-03-31 Illumina, Inc. Methods of making and using composite arrays for the detection of a plurality of target analytes
US6368563B1 (en) * 1999-03-12 2002-04-09 Integ, Inc. Collection well for body fluid tester
US6355431B1 (en) 1999-04-20 2002-03-12 Illumina, Inc. Detection of nucleic acid amplification reactions using bead arrays
US20030207295A1 (en) * 1999-04-20 2003-11-06 Kevin Gunderson Detection of nucleic acid reactions on bead arrays
US20060275782A1 (en) * 1999-04-20 2006-12-07 Illumina, Inc. Detection of nucleic acid reactions on bead arrays
WO2000075373A2 (fr) 1999-05-20 2000-12-14 Illumina, Inc. Decodage combinatoire de jeux d'acides nucleiques aleatoires
US6544732B1 (en) 1999-05-20 2003-04-08 Illumina, Inc. Encoding and decoding of array sensors utilizing nanocrystals
US8481268B2 (en) 1999-05-21 2013-07-09 Illumina, Inc. Use of microfluidic systems in the detection of target analytes using microsphere arrays
US8080380B2 (en) * 1999-05-21 2011-12-20 Illumina, Inc. Use of microfluidic systems in the detection of target analytes using microsphere arrays
US7426409B2 (en) * 1999-06-25 2008-09-16 Board Of Regents, The University Of Texas System Method and apparatus for detecting vulnerable atherosclerotic plaque
ATE542916T1 (de) 1999-08-18 2012-02-15 Illumina Inc Methoden zur erzeugung von oligonukleotidlösungen
EP1212599A2 (fr) 1999-08-30 2002-06-12 Illumina, Inc. Procedes permettant d'ameliorer la detection de signaux dans un jeu d'echantillons
DE19941270C1 (de) * 1999-08-31 2001-06-28 Lienhard Pagel Mikrofluidisches pH-Sensormodul
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
EP1122535A3 (fr) * 2000-01-31 2004-09-22 The Penn State Research Foundation Procédé de contrôle du contenu d'un récipient scellé
AU2001238067B2 (en) 2000-02-07 2007-01-25 Illumina, Inc. Nucleic acid detection methods using universal priming
US8076063B2 (en) * 2000-02-07 2011-12-13 Illumina, Inc. Multiplexed methylation detection methods
DE60136166D1 (de) 2000-02-07 2008-11-27 Illumina Inc Nukleinsäure-nachweisverfahren mit universellem priming
US7582420B2 (en) 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
US7611869B2 (en) * 2000-02-07 2009-11-03 Illumina, Inc. Multiplexed methylation detection methods
US6913884B2 (en) * 2001-08-16 2005-07-05 Illumina, Inc. Compositions and methods for repetitive use of genomic DNA
US7361488B2 (en) * 2000-02-07 2008-04-22 Illumina, Inc. Nucleic acid detection methods using universal priming
US7955794B2 (en) 2000-09-21 2011-06-07 Illumina, Inc. Multiplex nucleic acid reactions
US20050214825A1 (en) * 2000-02-07 2005-09-29 John Stuelpnagel Multiplex sample analysis on universal arrays
US6770441B2 (en) * 2000-02-10 2004-08-03 Illumina, Inc. Array compositions and methods of making same
JP4954415B2 (ja) * 2000-02-10 2012-06-13 イルミナ インコーポレイテッド 試料のビーズをベースとした同時プロセシングのための基材としての個々のアレイのアレイおよびその製造法
AU2001238389B2 (en) 2000-02-16 2006-09-21 Illumina, Inc. Parallel genotyping of multiple patient samples
US8527046B2 (en) 2000-04-20 2013-09-03 Medtronic, Inc. MRI-compatible implantable device
US6925328B2 (en) 2000-04-20 2005-08-02 Biophan Technologies, Inc. MRI-compatible implantable device
US20050158702A1 (en) * 2000-09-05 2005-07-21 Stuelpnagel John R. Cellular arrays comprising encoded cells
US20040018491A1 (en) * 2000-10-26 2004-01-29 Kevin Gunderson Detection of nucleic acid reactions on bead arrays
EP1213583A1 (fr) * 2000-12-06 2002-06-12 Innosense S.r.l. Méthode générale d'immobilisation d'indicateurs dans ou sur des supports utiles à la fabrication de capteurs optiques
US20040243093A1 (en) * 2001-01-10 2004-12-02 Ron Berenson System for growth, analysis, storage, validation and distribution of cells and tissues used for biomedical purposes
US20020116029A1 (en) 2001-02-20 2002-08-22 Victor Miller MRI-compatible pacemaker with power carrying photonic catheter and isolated pulse generating electronics providing VOO functionality
US6829509B1 (en) * 2001-02-20 2004-12-07 Biophan Technologies, Inc. Electromagnetic interference immune tissue invasive system
US7054686B2 (en) * 2001-08-30 2006-05-30 Biophan Technologies, Inc. Pulsewidth electrical stimulation
US6731979B2 (en) 2001-08-30 2004-05-04 Biophan Technologies Inc. Pulse width cardiac pacing apparatus
US6734386B1 (en) 2001-09-24 2004-05-11 Meissner Filtration Products, Inc. Method for rendering PVDF membrane hydrophilic
US6988001B2 (en) * 2001-10-31 2006-01-17 Biophan Technologies, Inc. Hermetic component housing for photonic catheter
US6968236B2 (en) * 2002-01-28 2005-11-22 Biophan Technologies, Inc. Ceramic cardiac electrodes
AU2003215240A1 (en) 2002-02-14 2003-09-04 Illumina, Inc. Automated information processing in randomly ordered arrays
US6711440B2 (en) 2002-04-11 2004-03-23 Biophan Technologies, Inc. MRI-compatible medical device with passive generation of optical sensing signals
US6725092B2 (en) 2002-04-25 2004-04-20 Biophan Technologies, Inc. Electromagnetic radiation immune medical assist device adapter
AU2003239375A1 (en) * 2002-05-07 2003-11-11 Volcano Therapeutics, Inc. Systems and methods for detecting vulnerable plaque
KR100505021B1 (ko) * 2002-07-25 2005-08-01 박상규 진단계측기용 센서
US6925322B2 (en) * 2002-07-25 2005-08-02 Biophan Technologies, Inc. Optical MRI catheter system
US20040259105A1 (en) * 2002-10-03 2004-12-23 Jian-Bing Fan Multiplex nucleic acid analysis using archived or fixed samples
WO2004065000A1 (fr) * 2003-01-21 2004-08-05 Illumina Inc. Moniteur de reactions chimiques
US7419483B2 (en) * 2003-02-07 2008-09-02 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Surgical drain with positioning and protective features
US6943768B2 (en) 2003-02-21 2005-09-13 Xtellus Inc. Thermal control system for liquid crystal cell
IL161096A (en) * 2003-03-27 2008-08-07 Given Imaging Ltd An instrument, system, and method for measuring a cascade of intracorporeal concentrations
US8343074B2 (en) * 2004-06-30 2013-01-01 Lifescan Scotland Limited Fluid handling devices
WO2006023725A2 (fr) 2004-08-19 2006-03-02 Blood Cell Storage, Inc Systeme de detecteur de ph fluorescent et procedes associes
US8183052B2 (en) * 2004-08-19 2012-05-22 Blood Cell Storage, Inc. Methods and apparatus for sterility testing
US8497134B2 (en) * 2004-08-19 2013-07-30 Blood Cell Storage, Inc. Fluorescent detector systems for the detection of chemical perturbations in sterile storage devices
GB2420849B (en) 2004-12-02 2007-06-27 Schlumberger Holdings Optical pH sensor
TWI258123B (en) * 2005-02-03 2006-07-11 Lite On It Corp Apparatus for positioning a clamper of a disc driver
US20060246576A1 (en) 2005-04-06 2006-11-02 Affymetrix, Inc. Fluidic system and method for processing biological microarrays in personal instrumentation
US7473906B2 (en) 2005-04-28 2009-01-06 Claudio Oliveira Egalon Reversible, low cost, distributed optical fiber sensor with high spatial resolution
US20060266366A1 (en) * 2005-05-25 2006-11-30 Ross Tsukashima Illumination means for catheter placement
DE102005033926B4 (de) * 2005-07-15 2011-05-12 Bundesrepublik Deutschland, vertreten durch den Präsidenten der Bundesanstalt für Geowissenschaften und Rohstoffe Messvorrichtung und Messverfahren zum Messen des pH-Werts einer Probe
US20110125203A1 (en) * 2009-03-20 2011-05-26 ElectroCore, LLC. Magnetic Stimulation Devices and Methods of Therapy
WO2007081811A2 (fr) 2006-01-04 2007-07-19 The Trustees Of The University Of Pennsylvania Capteur d'oxygene destine au controle interne d'oxygene tissulaire in vivo
US8460879B2 (en) * 2006-02-21 2013-06-11 The Trustees Of Tufts College Methods and arrays for target analyte detection and determination of target analyte concentration in solution
US11237171B2 (en) 2006-02-21 2022-02-01 Trustees Of Tufts College Methods and arrays for target analyte detection and determination of target analyte concentration in solution
GB2437057A (en) * 2006-04-12 2007-10-17 Sean Julian Thomas Tube having positioning means for delivering fluid to a predetermining location
US7809441B2 (en) 2006-05-17 2010-10-05 Cardiac Pacemakers, Inc. Implantable medical device with chemical sensor and related methods
US20080003667A1 (en) * 2006-05-19 2008-01-03 Affymetrix, Inc. Consumable elements for use with fluid processing and detection systems
US20080086112A1 (en) * 2006-10-06 2008-04-10 National Health Research Institute (An Institution Of Taiwan, R.O.C.) Microdevice for detecting, activating and delivering molecules
EP2120680A2 (fr) 2007-02-06 2009-11-25 Glumetrics, Inc. Systèmes et procédés optiques pour la mesure ratiométrique de la concentration en glucose dans le sang
JP5517919B2 (ja) 2007-05-10 2014-06-11 グルメトリクス、 インク． 即時血管内グルコース測定のための平衡非消費蛍光センサー
CA2734029C (fr) 2007-08-30 2016-03-29 The Trustees Of Tufts College Procedes pour determiner la concentration d'un analyte dans une solution
WO2009067626A1 (fr) * 2007-11-21 2009-05-28 Glumetrics, Inc. Utilisation d'un capteur intravasculaire à l'équilibre pour parvenir à une maîtrise précise de la glycémie
US8280471B2 (en) * 2007-12-12 2012-10-02 Kimberly-Clark Worldwide, Inc. Fiber optic based detection of autofluorescent bacterial pathogens
US20090155770A1 (en) * 2007-12-12 2009-06-18 Kimberly-Clark Worldwide, Inc. Implantable devices for fiber optic based detection of nosocomial infection
WO2009129186A2 (fr) * 2008-04-17 2009-10-22 Glumetrics, Inc. Capteur pour déploiement intra-vasculaire percutané sans canule à demeure
US20100075862A1 (en) * 2008-09-23 2010-03-25 Quanterix Corporation High sensitivity determination of the concentration of analyte molecules or particles in a fluid sample
US20100075439A1 (en) * 2008-09-23 2010-03-25 Quanterix Corporation Ultra-sensitive detection of molecules by capture-and-release using reducing agents followed by quantification
US8222047B2 (en) 2008-09-23 2012-07-17 Quanterix Corporation Ultra-sensitive detection of molecules on single molecule arrays
US7961327B1 (en) 2009-01-07 2011-06-14 Bovaird & Co. Optical pH sensor
US8463083B2 (en) * 2009-01-30 2013-06-11 Claudio Oliveira Egalon Side illuminated multi point multi parameter optical fiber sensor
US9523701B2 (en) 2009-07-29 2016-12-20 Dynex Technologies, Inc. Sample plate systems and methods
GB0913258D0 (en) 2009-07-29 2009-09-02 Dynex Technologies Inc Reagent dispenser
WO2011041546A1 (fr) 2009-09-30 2011-04-07 Glumetrics, Inc. Capteurs dotés de revêtements thromborésistants
US8467843B2 (en) 2009-11-04 2013-06-18 Glumetrics, Inc. Optical sensor configuration for ratiometric correction of blood glucose measurement
US20110152658A1 (en) * 2009-12-17 2011-06-23 Glumetrics, Inc. Identification of aberrant measurements of in vivo glucose concentration using temperature
US8694069B1 (en) 2009-12-21 2014-04-08 Kosense, LLC Fiber-optic probe with embedded peripheral sensors for in-situ continuous monitoring
US8415171B2 (en) 2010-03-01 2013-04-09 Quanterix Corporation Methods and systems for extending dynamic range in assays for the detection of molecules or particles
ES2544635T3 (es) 2010-03-01 2015-09-02 Quanterix Corporation Métodos para extender el rango dinámico en ensayos para la detección de moléculas o partículas
US9678068B2 (en) * 2010-03-01 2017-06-13 Quanterix Corporation Ultra-sensitive detection of molecules using dual detection methods
US8236574B2 (en) 2010-03-01 2012-08-07 Quanterix Corporation Ultra-sensitive detection of molecules or particles using beads or other capture objects
CN105462826B (zh) * 2010-07-20 2018-01-12 生物梅里埃有限公司 具有比色传感器的血液培养瓶的探测器装置
US9952237B2 (en) 2011-01-28 2018-04-24 Quanterix Corporation Systems, devices, and methods for ultra-sensitive detection of molecules or particles
JP5797911B2 (ja) * 2011-02-18 2015-10-21 日本光電工業株式会社 溶液のｐＨ計測方法及び溶液のｐＨ計測装置
WO2012142301A2 (fr) 2011-04-12 2012-10-18 Quanterix Corporation Procédé de détermination d'un protocole de traitement et/ou d'un pronostic de rétablissement d'un patient à la suite d'un traumatisme cérébral
US9040307B2 (en) 2011-05-27 2015-05-26 Blood Cell Storage, Inc. Fluorescent pH detector system and related methods
DE102011081326A1 (de) * 2011-08-22 2013-02-28 Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG Optischer Sensor, insbesondere zur Bestimmung von Stoffkonzentrationen in wässrigen Lösungen mittels einer Fluoreszenzmessung
CN104053991B (zh) * 2012-01-18 2016-09-14 生物梅里埃有限公司 用于具有比色传感器的血培养瓶的检测器装置
WO2014113502A1 (fr) 2013-01-15 2014-07-24 Quanterix Corporation Détection de l'adn ou de l'arn au moyen de matrices de molécules simples et d'autres techniques
GB2525679A (en) * 2014-05-02 2015-11-04 Univ Singapore A disposable measurement tip and method for use thereof
US10011542B2 (en) * 2015-04-24 2018-07-03 Baker Hughes, A Ge Company, Llc Methods of measuring pH in refinery streams
US10716500B2 (en) 2015-06-29 2020-07-21 Cardiac Pacemakers, Inc. Systems and methods for normalization of chemical sensor data based on fluid state changes
CN108968976B (zh) 2017-05-31 2022-09-13 心脏起搏器股份公司 具有化学传感器的植入式医疗设备
CN109381195B (zh) 2017-08-10 2023-01-10 心脏起搏器股份公司 包括电解质传感器融合的系统和方法
CN109419515B (zh) 2017-08-23 2023-03-24 心脏起搏器股份公司 具有分级激活的可植入化学传感器
US20190261897A1 (en) 2017-11-28 2019-08-29 Alan D. Kersey Apparatus and method for assessment of cancer margin
CN109864746B (zh) 2017-12-01 2023-09-29 心脏起搏器股份公司 用于医学装置的多模式分析物传感器
CN109864747B (zh) 2017-12-05 2023-08-25 心脏起搏器股份公司 多模式分析物传感器光电子接口
DE102018204744A1 (de) * 2018-03-28 2019-10-02 Robert Bosch Gmbh Chemische Analysevorrichtung zur Messung der Ionenkonzentration eines Elektrolyten und Verfahren zu ihrem Betrieb
DE102019113951A1 (de) * 2019-05-24 2020-11-26 Sentronic GmbH - Gesellschaft für optische Meßsysteme Funktionsschichtträger und Sensorsystem umfassend einen derartigen Funktionsschichtträger

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3335715A (en) * 1964-09-18 1967-08-15 American Optical Corp Fiber optic catheter
US3807390A (en) * 1972-12-04 1974-04-30 American Optical Corp Fiber optic catheter
US3814081A (en) * 1971-04-02 1974-06-04 Olympus Optical Co Optical measuring catheter

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2084399A (en) * 1935-12-12 1937-06-22 Du Pont Polymerization process
CH298194A (de) * 1951-08-29 1954-04-30 Ciba Geigy Analytisches Verfahren unter Verwendung von Derivaten von Säure-Basen-Indikatorfarbstoffen.
FR1065648A (fr) * 1951-08-29 1954-05-28 Ciba Geigy Nouveaux dérivés d'indicateurs colorés sensibles aux acides et aux bases, leur préparation et leur utilisation
GB770889A (en) 1952-01-10 1957-03-27 American Cyanamid Co Improvements relating to fluorescent pigments
US2937186A (en) * 1958-04-29 1960-05-17 Univ Kansas Res Foundation Isothiocyanate compounds and means of producing the same
US3164663A (en) * 1960-10-27 1965-01-05 Beckman Instruments Inc Probe for colorimetric measurement
US3183208A (en) * 1961-08-22 1965-05-11 Koppers Co Inc Incorporating finely divided particles during suspension polymerization
DE2061009A1 (de) * 1969-12-18 1971-06-24 Exploaterings Ab Tbf Verfahren zur Fixierung von Polymeren
FR2123875A5 (fr) * 1971-01-29 1972-09-15 Rybak Boris
US4016133A (en) * 1974-03-18 1977-04-05 Sinloihi Co. Fluorescent colored resin particles and process for preparation thereof
US4041932A (en) * 1975-02-06 1977-08-16 Fostick Moshe A Method for monitoring blood gas tension and pH from outside the body
US4016863A (en) * 1975-08-27 1977-04-12 Brantigan John W Tissue tonometer device for use in measuring gas in body tissue
US4033330A (en) * 1975-09-08 1977-07-05 Hewlett-Packard Company Transcutaneous pH measuring instrument
US4194877A (en) * 1977-11-28 1980-03-25 United States Of America Dye-containing polymer composition

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3335715A (en) * 1964-09-18 1967-08-15 American Optical Corp Fiber optic catheter
US3814081A (en) * 1971-04-02 1974-06-04 Olympus Optical Co Optical measuring catheter
US3807390A (en) * 1972-12-04 1974-04-30 American Optical Corp Fiber optic catheter

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2461255A1 (fr) * 1979-07-10 1981-01-30 Hellige Gmbh Procede et dispositif pour la determination photometrique transcutanee de la concentration de constituants du sang
EP0036017A1 (fr) * 1979-09-20 1981-09-23 Richard G Buckles Appareil d'analyses.
EP0036017A4 (fr) * 1979-09-20 1982-02-05 Richard G Buckles Appareil d'analyses.
EP0073558A2 (fr) * 1981-08-25 1983-03-09 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce Capteur à fibres optiques pour la mesure de pH de tissus
EP0073558A3 (fr) * 1981-08-25 1984-09-26 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce Capteur à fibres optiques pour la mesure de pH de tissus
EP0080411A1 (fr) * 1981-11-20 1983-06-01 Societe D'etudes Scientifiques Et Industrielles De L'ile-De-France Indicateur coloré pour la détermination de l'hypoacidité de la muqueuse gastrique au cours de la gastroscopie
EP0321924A2 (fr) * 1987-12-23 1989-06-28 Willi Möller AG Matériau polymérique pouvant former une couche stable de protéine à sa surface après contact avec un matériau contenant des protéines, et utilisation de ce matériau polymérique
EP0321924A3 (en) * 1987-12-23 1989-10-25 Willi Moller Ag Polymeric material which, when in contact with a protein-containing material, forms a stable protein layer on its surface, and use of such a polymeric material

Also Published As

Publication number Publication date
DE2851138A1 (de) 1979-06-07
JPS5485588A (en) 1979-07-07
US4200110A (en) 1980-04-29
FR2409743B1 (fr) 1984-01-06
GB2009394B (en) 1982-06-30
JPS6159727B2 (fr) 1986-12-17
NL7811372A (nl) 1979-05-30
CA1121242A (fr) 1982-04-06
DE2851138C2 (fr) 1990-07-05
GB2009394A (en) 1979-06-13

Similar Documents

Publication Publication Date Title
FR2409743A1 (fr) Sonde de ph a fibres optiques
DE69627477T2 (de) Optische koppelvorrichtung zur in-vivo untersuchung von biologischen geweben
Dennis et al. Some physiological properties of identified mammalian neuroglial cells
EP0567447B1 (fr) Arrangement de sonde pour la détermination directe ou indirecte de paramètre physique ou chimique
US6593101B2 (en) Enhancing contrast in biological imaging
EP0073558A2 (fr) Capteur à fibres optiques pour la mesure de pH de tissus
Maitland et al. In vivo imaging of oral neoplasia using a miniaturized fiber optic confocal reflectance microscope
JP2583730B2 (ja) センサー装置
DE69532938T2 (de) Optischer Glukose-Sensor
Prausnitz et al. Imaging regions of transport across human stratum corneum during high-voltage and low-voltage exposures
DE59812090D1 (de) Analysevorrichtung zur in-vivo-analyse im körper eines patienten
HUP0003132A2 (hu) Nem saválló és enzimatikusan hasítható színezékösszetételek közeli infravörös fénnyel végzett diagnosztikához és terápiához
Steiner et al. Optical coherence tomography: clinical applications in dermatology
DE2726450B2 (de) Katheter-Meßanordnung zur elektrochemischen Analyse
CH665345A5 (de) Sonde zum bestimmen des sauerstoffpartialdruckes.
DE2061098A1 (de) Oximeter
US4900381A (en) Method for manufacturing a measuring probe
ATE425697T1 (de) Kalibrierungsfluid fur einen sensor zur messung eines blutwertes, sowie herstellung des kalibrierungsfluids
Papworth et al. In vivo fibre optic confocal imaging of microvasculature and nerves in the rat vas deferens and colon
CN106841145B (zh) 二次谐波成像结合荧光成像在定位物质透皮吸收中的应用
JP3255373B2 (ja) 生体内計測装置
DE60018736T2 (de) Optisches biopsiesystem
DE19854292C2 (de) Verfahren und Anordnung zur multiparametrischen Diagnostik von biologischem Gewebe
Delpy Optical spectroscopy for diagnosis
DE3231483C2 (fr)