FR2377632A1 - Procede et produits pour doser la bilirubine dans des liquides, tels que des liquides biologiques - Google Patents
Procede et produits pour doser la bilirubine dans des liquides, tels que des liquides biologiquesInfo
- Publication number
- FR2377632A1 FR2377632A1 FR7800873A FR7800873A FR2377632A1 FR 2377632 A1 FR2377632 A1 FR 2377632A1 FR 7800873 A FR7800873 A FR 7800873A FR 7800873 A FR7800873 A FR 7800873A FR 2377632 A1 FR2377632 A1 FR 2377632A1
- Authority
- FR
- France
- Prior art keywords
- bilirubin
- liquids
- products
- mordant
- layer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/728—Bilirubin; including biliverdin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/145555—Hetero-N
- Y10T436/146666—Bile pigment
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Abstract
L'invention concerne un dosage colorimétrique de la bilirubine. Suivant l'invention, on fait réagir la bilirubine en solution avec un mordant, tel qu'un composé ammonium ou phosphonium quaternaire polymère, à caractère hydrophobe; le mordançage modifie le pic d'absorption spectrale et augmente fortement le coefficient d'extinction molaire de la bilirubine. Application au dosage par spectrophotométrie de la bilirubine dans le sang et dans les autres liquides biologiques, notamment par touche sur un produit analytique comprenant une couche avec le mordant, une couche 6 assurant l'étalement d'une goutte de liquide et un support 8.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/759,529 US4069017A (en) | 1977-01-14 | 1977-01-14 | Colorimetric assay for bilirubin |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2377632A1 true FR2377632A1 (fr) | 1978-08-11 |
FR2377632B1 FR2377632B1 (fr) | 1980-07-04 |
Family
ID=25055997
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7800873A Granted FR2377632A1 (fr) | 1977-01-14 | 1978-01-13 | Procede et produits pour doser la bilirubine dans des liquides, tels que des liquides biologiques |
Country Status (9)
Country | Link |
---|---|
US (1) | US4069017A (fr) |
JP (2) | JPS5389796A (fr) |
BE (1) | BE862956A (fr) |
CA (1) | CA1094432A (fr) |
CH (1) | CH627555A5 (fr) |
DE (1) | DE2801476C2 (fr) |
FR (1) | FR2377632A1 (fr) |
GB (1) | GB1591683A (fr) |
SE (1) | SE443048B (fr) |
Families Citing this family (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4069017A (en) * | 1977-01-14 | 1978-01-17 | Eastman Kodak Company | Colorimetric assay for bilirubin |
US4153668A (en) * | 1978-01-03 | 1979-05-08 | Eastman Kodak Company | Multi-zone analytical element and method using same |
US4260392A (en) * | 1978-07-07 | 1981-04-07 | Technicon Instruments Corporation | Method and apparatus for obtaining an aliquot of a liquid in a gel medium |
US4204839A (en) * | 1978-08-09 | 1980-05-27 | Eastman Kodak Company | Fluorimetric analysis method for bilirubin |
US4258001A (en) * | 1978-12-27 | 1981-03-24 | Eastman Kodak Company | Element, structure and method for the analysis or transport of liquids |
US4381921A (en) * | 1978-12-27 | 1983-05-03 | Eastman Kodak Company | Element, structure and method for the analysis or transport of liquids |
US4288228A (en) * | 1979-01-31 | 1981-09-08 | Technicon Instruments Corporation | Whole blood analyses and diffusion apparatus therefor |
US4274832A (en) * | 1979-02-12 | 1981-06-23 | Eastman Kodak Company | Analytical element and method for analysis of multiple analytes |
US4311665A (en) * | 1979-07-11 | 1982-01-19 | Eastman Kodak Company | Separation and isolation of conjugated and unconjugated bilirubin |
CA1128333A (fr) * | 1979-07-11 | 1982-07-27 | Tai-Wing Wu | Analyse de la bilirubine conjuguee et non conjuguee |
JPS5524694A (en) * | 1979-08-09 | 1980-02-21 | Eastman Kodak Co | Fluorescent analysis for bilirubin |
US4412005A (en) * | 1979-10-25 | 1983-10-25 | Eastman Kodak Company | Determination of total bilirubin |
US4338095A (en) * | 1980-07-11 | 1982-07-06 | Eastman Kodak Company | Method for selective determination of conjugated and unconjugated bilirubin |
DE3029579C2 (de) * | 1980-08-05 | 1985-12-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und Mittel zur Abtrennung von Plasma oder Serum aus Vollblut |
US4816224A (en) * | 1980-08-05 | 1989-03-28 | Boehringer Mannheim Gmbh | Device for separating plasma or serum from whole blood and analyzing the same |
JPS5737262A (en) * | 1980-08-19 | 1982-03-01 | Fuji Photo Film Co Ltd | Analyzing method for bilirubin and multilayer analysis material for said method |
JPS59145965A (ja) * | 1983-02-09 | 1984-08-21 | Fuji Photo Film Co Ltd | ビリルビン定量用分析要素 |
USH791H (en) | 1983-03-18 | 1990-06-05 | Harumi Katsuyama | Multilayer analytical element for quantitative analysis of bilirubin |
JPS59171864A (ja) * | 1983-03-18 | 1984-09-28 | Fuji Photo Film Co Ltd | ビリルビン定量用多層分析要素 |
JPS6014141A (ja) * | 1983-07-06 | 1985-01-24 | Kyoto Daiichi Kagaku:Kk | 多層一体化分析用具 |
US4701411A (en) * | 1983-09-01 | 1987-10-20 | Eastman Kodak Company | Bilirubin-specific enzyme preparation, assay compositions, analytical elements and methods using same |
DE3333720A1 (de) * | 1983-09-17 | 1985-03-28 | Bayer Ag, 5090 Leverkusen | Verfahren zum entfernen von wasser aus phosgenhaltigen organischen loesungsmitteln und neue anionenaustauscher zur durchfuehrung des verfahrens |
US4627014A (en) * | 1984-04-09 | 1986-12-02 | Eastman Kodak Company | Method and apparatus for determination of an analyte and method of calibrating such apparatus |
US4548905A (en) * | 1984-04-09 | 1985-10-22 | Eastman Kodak Company | Reagent composition, dry element and method for determination of total bilirubin |
US4547465A (en) * | 1984-04-16 | 1985-10-15 | Eastman Kodak Company | Analytical element having improved spreading zone and method of use |
US4547460A (en) * | 1984-04-16 | 1985-10-15 | Eastman Kodak Company | Multizone analytical element and method for analyte determination |
DE3587159T2 (de) * | 1984-04-27 | 1993-08-19 | Fuji Photo Film Co Ltd | Analytisches element zur analyse einer vollblutprobe. |
JPS62138198A (ja) * | 1985-12-10 | 1987-06-20 | Fuji Photo Film Co Ltd | 自己顕色性基質を含む乾式液体分析要素 |
US4803160A (en) * | 1986-01-31 | 1989-02-07 | Eastman Kodak Company | Use of polymeric mordants to increase the intensity of rigid fluorescent dyes |
US4737457A (en) * | 1986-02-26 | 1988-04-12 | Eastman Kodak Company | Analytical composition, element and method for the determination of hydrogen peroxide |
US4935346A (en) | 1986-08-13 | 1990-06-19 | Lifescan, Inc. | Minimum procedure system for the determination of analytes |
US4788153A (en) * | 1986-10-14 | 1988-11-29 | Eastman Kodak Company | Method for the determination of bilirubin and an element useful therein |
US4810470A (en) * | 1987-06-19 | 1989-03-07 | Miles Inc. | Volume independent diagnostic device |
US4766080A (en) * | 1987-08-28 | 1988-08-23 | Miles Inc. | Quantitative measurement of lithium |
JPH0249163A (ja) * | 1988-05-20 | 1990-02-19 | Konica Corp | 多層分析素子 |
US5156954A (en) * | 1989-03-08 | 1992-10-20 | Cholestech Corporation | Assay device and method using a signal-modulating compound |
US5171688A (en) * | 1988-08-30 | 1992-12-15 | Cholestech Corporation | Self-corrected assay device |
US5114350A (en) * | 1989-03-08 | 1992-05-19 | Cholestech Corporation | Controlled-volume assay apparatus |
US5110724A (en) * | 1990-04-02 | 1992-05-05 | Cholestech Corporation | Multi-analyte assay device |
US5212060A (en) * | 1990-04-27 | 1993-05-18 | Genesis Labs, Inc. | Dry test strip comprising a dextran barrier for excluding erythrocytes |
EP0575364B1 (fr) * | 1991-02-28 | 1996-04-24 | Roche Diagnostics GmbH | Support de test pour la determination d'un echantillon de sang total a analyser |
US5186843A (en) * | 1991-07-22 | 1993-02-16 | Ahlstrom Filtration, Inc. | Blood separation media and method for separating plasma from whole blood |
US5393469A (en) * | 1992-03-20 | 1995-02-28 | Lumigen, Inc. | Polymeric phosphonium salts providing enhanced chemiluminescence from 1,2-dioxetanes |
US5286450A (en) * | 1992-06-01 | 1994-02-15 | Eastman Kodak Company | Bilirubin assay using crosslinkable polymers |
US5710005A (en) * | 1996-10-29 | 1998-01-20 | Biocode, Inc. | Analyte detection with a gradient lateral flow device |
US5891054A (en) * | 1997-09-12 | 1999-04-06 | Saint Louis University | Method for determining feeding the tube location |
US6908770B1 (en) | 1998-07-16 | 2005-06-21 | Board Of Regents, The University Of Texas System | Fluid based analysis of multiple analytes by a sensor array |
WO2001006244A2 (fr) | 1999-07-16 | 2001-01-25 | Board Of Regents, The University Of Texas System | Protocoles generaux de signalisation de recepteurs chimiques dans des matrices immobilisees |
US7022517B1 (en) | 1999-07-16 | 2006-04-04 | Board Of Regents, The University Of Texas System | Method and apparatus for the delivery of samples to a chemical sensor array |
US6458326B1 (en) | 1999-11-24 | 2002-10-01 | Home Diagnostics, Inc. | Protective test strip platform |
DE60135092D1 (de) | 2000-01-31 | 2008-09-11 | Univ Texas | Tragbare vorrichtung mit einer sensor-array-anordnung |
JP4474010B2 (ja) * | 2000-03-15 | 2010-06-02 | アークレイ株式会社 | 固体成分分離能を有する試験片 |
US6541266B2 (en) | 2001-02-28 | 2003-04-01 | Home Diagnostics, Inc. | Method for determining concentration of an analyte in a test strip |
US6562625B2 (en) * | 2001-02-28 | 2003-05-13 | Home Diagnostics, Inc. | Distinguishing test types through spectral analysis |
US6525330B2 (en) | 2001-02-28 | 2003-02-25 | Home Diagnostics, Inc. | Method of strip insertion detection |
US6774249B2 (en) | 2001-09-27 | 2004-08-10 | Lumigen, Inc. | Uses of improved polymer-supported photosensitizers in the generation of singlet oxygen |
EP1357383B1 (fr) * | 2002-04-09 | 2005-11-09 | Cholestech Corporation | Méthode et dispositif de test permettant de doser le cholesterol HDL (lipoproteine à haute densité) |
US8257967B2 (en) * | 2002-04-26 | 2012-09-04 | Board Of Regents, The University Of Texas System | Method and system for the detection of cardiac risk factors |
EP1590659A4 (fr) * | 2003-02-07 | 2010-04-21 | Univ Texas | Microspheres a coques multiples a couches de chromatographie et de detection integrees utilisees dans des capteurs en mosaiques |
US20050180879A1 (en) * | 2004-02-03 | 2005-08-18 | Eva Hrboticka | One step tester for ammonia |
US8105849B2 (en) * | 2004-02-27 | 2012-01-31 | Board Of Regents, The University Of Texas System | Integration of fluids and reagents into self-contained cartridges containing sensor elements |
US8101431B2 (en) * | 2004-02-27 | 2012-01-24 | Board Of Regents, The University Of Texas System | Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems |
EP1910824A4 (fr) | 2005-05-31 | 2012-11-21 | Labnow Inc | Méthodes et compositions en rapport avec la détermination et l utilisation de la numération de globules blancs |
CA2613078A1 (fr) * | 2005-06-24 | 2007-01-04 | Board Of Regents, The University Of Texas System | Systemes et procedes faisant appel a des cartouches autonomes comprenant des systemes de detection et des systemes de distribution de fluides |
WO2007005666A2 (fr) * | 2005-07-01 | 2007-01-11 | Board Of Regents, The University Of Texas System | Systeme et methode de detection d'analytes au moyen de recepteurs differentiels |
US8003399B2 (en) * | 2005-08-31 | 2011-08-23 | Kimberly-Clark Worldwide, Inc. | Nitrite detection technique |
US7846383B2 (en) * | 2006-12-15 | 2010-12-07 | Kimberly-Clark Worldwide, Inc. | Lateral flow assay device and absorbent article containing same |
WO2008086019A1 (fr) * | 2007-01-09 | 2008-07-17 | Cholestech Corporation | Dispositif et procédé de mesure du cholestérol associé au ldl |
CA2697357A1 (fr) * | 2007-04-16 | 2008-10-30 | John T. Mcdevitt | Cardibioindice/cardibioscore et utilite d'un proteome salivaire dans des diagnostics cardiovasculaires |
JP5660867B2 (ja) * | 2010-11-26 | 2015-01-28 | 関東化学株式会社 | 色素成分の測定方法及び測定用試薬 |
US9759651B2 (en) | 2014-12-23 | 2017-09-12 | Magellan Diagnostics, Inc. | Combination optical hemoglobin and electrochemical lead assay |
WO2017117435A1 (fr) * | 2015-12-30 | 2017-07-06 | Magellan Diagnostics, Inc. | Capteur et analyse optiques de bilirubine |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2854317A (en) * | 1950-08-08 | 1958-09-30 | Miles Lab | Method and composition for testing bilirubin in urine |
AT316761B (de) * | 1971-03-05 | 1974-07-25 | Boehringer Mannheim Gmbh | Reagens zur Bestimmung von Gesamt-Bilirubin |
DE2240357C2 (de) * | 1972-08-17 | 1974-09-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | Testpapier zum Nachweis von Bilirubin in Körperflüssigkeiten |
US3814586A (en) * | 1973-01-02 | 1974-06-04 | Miles Lab | Composition,method and device for determining bilirubin and urobilinogen |
US3992158A (en) * | 1973-08-16 | 1976-11-16 | Eastman Kodak Company | Integral analytical element |
FR2280081A1 (fr) * | 1974-07-23 | 1976-02-20 | Kodak Pathe | Produit composite unitaire pour l'analyse chimique ou biologique |
JPS532096A (en) * | 1976-06-28 | 1978-01-10 | Fujitsu Ltd | Recording element |
US4069017A (en) * | 1977-01-14 | 1978-01-17 | Eastman Kodak Company | Colorimetric assay for bilirubin |
-
1977
- 1977-01-14 US US05/759,529 patent/US4069017A/en not_active Expired - Lifetime
- 1977-12-07 CA CA292,579A patent/CA1094432A/fr not_active Expired
-
1978
- 1978-01-13 DE DE2801476A patent/DE2801476C2/de not_active Expired
- 1978-01-13 CH CH37978A patent/CH627555A5/fr not_active IP Right Cessation
- 1978-01-13 FR FR7800873A patent/FR2377632A1/fr active Granted
- 1978-01-13 SE SE7800403A patent/SE443048B/sv not_active IP Right Cessation
- 1978-01-13 JP JP209678A patent/JPS5389796A/ja active Granted
- 1978-01-16 GB GB1673/78A patent/GB1591683A/en not_active Expired
- 1978-01-16 BE BE184366A patent/BE862956A/fr not_active IP Right Cessation
-
1981
- 1981-11-19 JP JP56184560A patent/JPS57160063A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
SE443048B (sv) | 1986-02-10 |
DE2801476A1 (de) | 1978-07-20 |
SE7800403L (sv) | 1978-07-15 |
CH627555A5 (fr) | 1982-01-15 |
JPS6222100B2 (fr) | 1987-05-15 |
US4069017A (en) | 1978-01-17 |
FR2377632B1 (fr) | 1980-07-04 |
DE2801476C2 (de) | 1982-12-09 |
BE862956A (fr) | 1978-07-17 |
GB1591683A (en) | 1981-06-24 |
JPS6339873B2 (fr) | 1988-08-08 |
JPS57160063A (en) | 1982-10-02 |
CA1094432A (fr) | 1981-01-27 |
JPS5389796A (en) | 1978-08-07 |
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