FR20C1038I1 - - Google Patents

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Publication number
FR20C1038I1
FR20C1038I1 FR20C1038C FR20C1038I1 FR 20C1038 I1 FR20C1038 I1 FR 20C1038I1 FR 20C1038 C FR20C1038 C FR 20C1038C FR 20C1038 I1 FR20C1038 I1 FR 20C1038I1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
Other languages
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of FR20C1038I1 publication Critical patent/FR20C1038I1/fr
Application granted granted Critical
Publication of FR20C1038I2 publication Critical patent/FR20C1038I2/fr
Active legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR20C1038C 2007-06-29 2020-08-20 Derives de benzamidazole Active FR20C1038I2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94728707P 2007-06-29 2007-06-29
US4164508P 2008-04-02 2008-04-02
PCT/IB2008/001575 WO2009004427A2 (en) 2007-06-29 2008-06-16 Benzimidazole derivatives

Publications (2)

Publication Number Publication Date
FR20C1038I1 true FR20C1038I1 (he) 2020-10-02
FR20C1038I2 FR20C1038I2 (fr) 2021-08-13

Family

ID=40161351

Family Applications (1)

Application Number Title Priority Date Filing Date
FR20C1038C Active FR20C1038I2 (fr) 2007-06-29 2020-08-20 Derives de benzamidazole

Country Status (46)

Country Link
US (2) US8148401B2 (he)
EP (1) EP2170860B9 (he)
JP (2) JP4567099B2 (he)
KR (1) KR101143246B1 (he)
CN (1) CN101687841B (he)
AP (1) AP2377A (he)
AR (1) AR067346A1 (he)
AU (1) AU2008272641B2 (he)
BR (1) BRPI0813412B8 (he)
CA (1) CA2690953C (he)
CL (1) CL2008001922A1 (he)
CO (1) CO6160232A2 (he)
CR (1) CR11150A (he)
CU (1) CU23847B1 (he)
CY (2) CY1118650T1 (he)
DK (1) DK2170860T5 (he)
DO (1) DOP2009000278A (he)
EA (1) EA016888B1 (he)
EC (1) ECSP099803A (he)
ES (1) ES2609258T3 (he)
FR (1) FR20C1038I2 (he)
GE (1) GEP20125702B (he)
GT (1) GT200900328A (he)
HK (1) HK1139658A1 (he)
HN (1) HN2008000974A (he)
HR (1) HRP20161562T2 (he)
HU (2) HUE030052T4 (he)
IL (1) IL202420A (he)
LT (2) LT2170860T (he)
MA (1) MA31466B1 (he)
ME (1) ME00962B (he)
MY (1) MY148636A (he)
NI (1) NI200900219A (he)
NL (1) NL301057I2 (he)
NO (1) NO2020027I1 (he)
NZ (1) NZ581889A (he)
PA (1) PA8785401A1 (he)
PE (2) PE20121010A1 (he)
PL (1) PL2170860T3 (he)
PT (1) PT2170860T (he)
RS (1) RS55395B9 (he)
SI (1) SI2170860T1 (he)
TN (1) TN2009000544A1 (he)
TW (1) TWI371451B (he)
UY (1) UY31164A1 (he)
WO (1) WO2009004427A2 (he)

Families Citing this family (31)

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WO2009004427A2 (en) * 2007-06-29 2009-01-08 Pfizer Inc. Benzimidazole derivatives
EP2330894B8 (en) 2008-09-03 2017-04-19 BioMarin Pharmaceutical Inc. Compositions including 6-aminohexanoic acid derivatives as hdac inhibitors
CN102803246A (zh) * 2009-06-11 2012-11-28 锡耶纳生物技术股份公司 Hedgehog途径拮抗剂及其治疗应用
CN102574851A (zh) 2009-08-26 2012-07-11 武田药品工业株式会社 稠合杂环衍生物及其用途
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US10010439B2 (en) 2010-06-13 2018-07-03 Synerz Medical, Inc. Intragastric device for treating obesity
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US8628554B2 (en) 2010-06-13 2014-01-14 Virender K. Sharma Intragastric device for treating obesity
ES2543151T3 (es) 2010-10-20 2015-08-17 Pfizer Inc Derivados de 2-piridina como moduladores del receptor Smoothened
JP5452459B2 (ja) 2010-12-16 2014-03-26 株式会社Ｎｔｔドコモ ホーム基地局及びハンドオーバ方法
US8957066B2 (en) 2011-02-28 2015-02-17 Biomarin Pharmaceutical Inc. Histone deacetylase inhibitors
US10059723B2 (en) 2011-02-28 2018-08-28 Biomarin Pharmaceutical Inc. Histone deacetylase inhibitors
DK2680694T3 (en) 2011-02-28 2019-03-25 Biomarin Pharm Inc HISTONDEACETYLASE INHIBITORS
WO2012122370A2 (en) * 2011-03-08 2012-09-13 Eutropics Pharmaceuticals, Inc. Compositions and methods useful for treating diseases
FR2980477B1 (fr) 2011-09-23 2013-10-18 Centre Nat Rech Scient Nouveaux composes modulateurs de la voie de signalisation des proteines hedgehog, leurs formes marquees, et applications
ES2612934T3 (es) * 2011-09-26 2017-05-19 Merck Patent Gmbh Compuestos de piperidin bencilo como antagonista del receptor del ácido lisofosfatídico (LPA)
US20150150869A1 (en) 2012-06-20 2015-06-04 Eutropics Pharmaceuticals, Inc. Methods and compositions useful for treating diseases involving bcl-2 family proteins with quinoline derivatives
EP2922544B1 (en) 2012-11-21 2018-08-01 Eutropics Pharmaceuticals, Inc. Methods and compositions useful for treating diseases involving bcl-2 family proteins with quinoline derivatives
ES2680224T3 (es) 2013-03-15 2018-09-05 Biomarin Pharmaceutical Inc. Inhibidores de HDAC
US10435364B2 (en) 2013-04-17 2019-10-08 Albert Ludwigs Universität Freiburg Compounds for use as bromodomain inhibitors
WO2015017788A1 (en) 2013-08-01 2015-02-05 Eutropics Pharmaceuticals, Inc. Method for predicting cancer sensitivity
GB2519344A (en) * 2013-10-18 2015-04-22 Redx Pharma Ltd Compounds
EP3063302B1 (en) 2013-10-30 2019-12-04 Eutropics Pharmaceuticals, Inc. Methods for determining chemosensitivity and chemotoxicity
KR102078444B1 (ko) 2015-04-24 2020-02-17 화이자 인코포레이티드 1-((2r,4r)-2-(1h-벤조[d]이미다졸-2-일)-1-메틸피페리딘-4-일)-3-(4-시아노페닐)우레아 말레에이트의 결정질 형태
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
JP2020164722A (ja) * 2019-03-29 2020-10-08 デクセリアルズ株式会社 接着剤組成物
ES2973822T3 (es) 2020-01-28 2024-06-24 Assia Chem Ind Ltd Procesos para la preparación de Glasdegib y su sal, y formas en estado sólido de maleato de Glasdegib y proceso para la preparación del mismo
CN113248475B (zh) * 2020-02-11 2023-03-17 中国科学院上海药物研究所 一类杂环取代的苯并咪唑二聚体或其药学上可接受的盐、组合物及其用途
WO2021191278A1 (en) 2020-03-26 2021-09-30 Lek Pharmaceuticals D.D. Dimaleate form of 1-((2r,4r)-2-(1h-benzo[d]imidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea
EP4173639A4 (en) 2020-06-26 2024-03-13 RaQualia Pharma Inc. METHOD FOR SELECTING A CANCER PATIENT WITH EFFECT OF COMBINATION THERAPY WITH RETINOID AND CANCER TREATMENT
WO2023002362A1 (en) 2021-07-22 2023-01-26 Pfizer Inc. Treatment of hematological malignancy

Family Cites Families (14)

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Publication number Priority date Publication date Assignee Title
WO2003011219A2 (en) 2001-07-27 2003-02-13 Curis, Inc. Mediators of hedgehog signaling pathways, compositions and uses related thereto
CA2473892C (en) * 2001-12-04 2010-09-21 Actelion Pharmaceuticals Ltd Novel quinoline derivatives
TW200304820A (en) 2002-03-25 2003-10-16 Avanir Pharmaceuticals Use of benzimidazole analogs in the treatment of cell proliferation
AU2003301436A1 (en) 2002-10-17 2004-05-04 Amgen Inc. Benzimidazole derivatives and their use as vanilloid receptor ligands
WO2005042495A1 (en) 2003-10-21 2005-05-12 Imclone Systems Incorporated (benzimidazol-2-yl)-phenyl-phenyl-urea compounds and methods for inhibiting heparanase activity
RU2006118312A (ru) 2003-10-28 2007-12-10 Вертекс Фармасьютикалз Инкорпорейтед (Us) Бензимидазолы, полезные в качестве модуляторов ионных каналов
CA2587489C (en) * 2004-11-03 2013-12-31 Curis, Inc. Mediators of hedgehog signaling pathways, compositions and uses related thereto
DE102005012875B4 (de) 2005-03-19 2006-11-16 Sanofi-Aventis Deutschland Gmbh Verwendung von Amino substituierten 8-N-Benzimidazolen
WO2006124780A2 (en) * 2005-05-12 2006-11-23 Kalypsys, Inc. Ih-benzo [d] imidazole compounds as inhibitors of b-raf kinase
WO2008064830A1 (en) 2006-11-27 2008-06-05 Ucb Pharma, S.A. Bicyclic and heterobicyclic derivatives, processes for preparing them and their pharmaceutical uses
WO2008075196A1 (en) 2006-12-15 2008-06-26 Pfizer Products Inc. Benzimidazole derivatives
WO2009004427A2 (en) * 2007-06-29 2009-01-08 Pfizer Inc. Benzimidazole derivatives
WO2009154739A2 (en) 2008-06-17 2009-12-23 Duke University Smoothened receptor modulators
JP5555236B2 (ja) 2008-08-25 2014-07-23 アイアールエム・リミテッド・ライアビリティ・カンパニー ヘッジホッグ経路モジュレーター

Also Published As

Publication number Publication date
ME00962B (me) 2012-06-20
RS55395B9 (sr) 2020-01-31
CY2020028I1 (el) 2020-11-25
JP4567099B2 (ja) 2010-10-20
KR101143246B1 (ko) 2012-05-18
TWI371451B (en) 2012-09-01
JP2010531869A (ja) 2010-09-30
AP2009005089A0 (en) 2009-12-31
MA31466B1 (fr) 2010-06-01
CY2020028I2 (el) 2020-11-25
SI2170860T1 (sl) 2017-01-31
NO2020027I1 (no) 2020-08-11
DOP2009000278A (es) 2009-12-31
CU23847B1 (es) 2012-10-15
PA8785401A1 (es) 2009-01-23
US20090005416A1 (en) 2009-01-01
CA2690953A1 (en) 2009-01-08
CN101687841A (zh) 2010-03-31
RS55395B1 (sr) 2017-04-28
TW200911792A (en) 2009-03-16
BRPI0813412B8 (pt) 2021-05-25
LTPA2020528I1 (lt) 2020-09-25
CN101687841B (zh) 2013-07-10
ECSP099803A (es) 2010-01-29
HN2008000974A (es) 2011-01-24
CR11150A (es) 2010-02-08
BRPI0813412B1 (pt) 2020-01-21
NI200900219A (es) 2010-03-11
PE20090772A1 (es) 2009-06-24
US8431597B2 (en) 2013-04-30
CY1118650T1 (el) 2017-07-12
UY31164A1 (es) 2009-01-30
CU20090225A7 (es) 2012-02-15
US20120157495A1 (en) 2012-06-21
WO2009004427A2 (en) 2009-01-08
DK2170860T5 (en) 2017-03-20
GEP20125702B (en) 2012-12-10
HUS2000031I1 (hu) 2020-09-28
CA2690953C (en) 2012-10-02
ES2609258T3 (es) 2017-04-19
KR20100028120A (ko) 2010-03-11
AP2377A (en) 2012-03-07
GT200900328A (es) 2011-08-29
IL202420A (he) 2014-05-28
MY148636A (en) 2013-05-15
EA200971104A1 (ru) 2010-06-30
EP2170860A2 (en) 2010-04-07
US8148401B2 (en) 2012-04-03
TN2009000544A1 (fr) 2011-03-31
AR067346A1 (es) 2009-10-07
DK2170860T3 (en) 2017-01-09
HK1139658A1 (en) 2010-09-24
NZ581889A (en) 2011-05-27
PL2170860T3 (pl) 2017-05-31
AU2008272641A1 (en) 2009-01-08
HRP20161562T2 (hr) 2017-04-21
EP2170860B1 (en) 2016-11-02
CO6160232A2 (es) 2010-05-20
PT2170860T (pt) 2017-01-04
IL202420A0 (en) 2010-06-30
FR20C1038I2 (fr) 2021-08-13
NL301057I1 (nl) 2020-07-22
HRP20161562T1 (hr) 2016-12-30
LT2170860T (lt) 2017-01-10
HUE030052T2 (hu) 2017-04-28
HUE030052T4 (en) 2017-06-28
WO2009004427A3 (en) 2009-06-04
EA016888B1 (ru) 2012-08-30
JP2010280693A (ja) 2010-12-16
PE20121010A1 (es) 2012-08-06
CL2008001922A1 (es) 2009-01-02
AU2008272641B2 (en) 2013-08-29
BRPI0813412A2 (pt) 2014-12-30
NL301057I2 (nl) 2020-09-10
EP2170860B9 (en) 2017-02-22
LTC2170860I2 (lt) 2022-03-10

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