FR15C0054I2 - Procedes de traitement de la maladie de parkinson - Google Patents

Procedes de traitement de la maladie de parkinson

Info

Publication number
FR15C0054I2
FR15C0054I2 FR15C0054C FR15C0054C FR15C0054I2 FR 15C0054 I2 FR15C0054 I2 FR 15C0054I2 FR 15C0054 C FR15C0054 C FR 15C0054C FR 15C0054 C FR15C0054 C FR 15C0054C FR 15C0054 I2 FR15C0054 I2 FR 15C0054I2
Authority
FR
France
Prior art keywords
parkinson
disease
treatment
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR15C0054C
Other languages
English (en)
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Newron Pharmaceuticals SpA
Original Assignee
Newron Pharmaceuticals SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33159845&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR15C0054(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Newron Pharmaceuticals SpA filed Critical Newron Pharmaceuticals SpA
Publication of FR15C0054I1 publication Critical patent/FR15C0054I1/fr
Application granted granted Critical
Publication of FR15C0054I2 publication Critical patent/FR15C0054I2/fr
Active legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/473Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/475Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/48Ergoline derivatives, e.g. lysergic acid, ergotamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR15C0054C 2003-04-11 2015-07-22 Procedes de traitement de la maladie de parkinson Active FR15C0054I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46220503P 2003-04-11 2003-04-11
PCT/IB2004/001408 WO2004089353A2 (en) 2003-04-11 2004-04-08 Methods for treatment of parkinson's disease

Publications (2)

Publication Number Publication Date
FR15C0054I1 FR15C0054I1 (fr) 2015-11-09
FR15C0054I2 true FR15C0054I2 (fr) 2018-01-26

Family

ID=33159845

Family Applications (1)

Application Number Title Priority Date Filing Date
FR15C0054C Active FR15C0054I2 (fr) 2003-04-11 2015-07-22 Procedes de traitement de la maladie de parkinson

Country Status (28)

Country Link
US (3) US8283380B2 (enExample)
EP (2) EP2070526B1 (enExample)
JP (2) JP2006522800A (enExample)
KR (2) KR101129015B1 (enExample)
CN (2) CN1771030A (enExample)
AR (1) AR044007A1 (enExample)
AT (1) ATE435012T1 (enExample)
AU (1) AU2004228782B2 (enExample)
BR (1) BRPI0409364A (enExample)
CA (1) CA2523188C (enExample)
CY (3) CY1109295T1 (enExample)
DE (1) DE602004021790D1 (enExample)
DK (2) DK1613296T3 (enExample)
ES (2) ES2454272T3 (enExample)
FR (1) FR15C0054I2 (enExample)
HU (1) HUS1500043I1 (enExample)
IL (2) IL171331A (enExample)
LU (1) LU92782I2 (enExample)
MX (1) MXPA05010873A (enExample)
NL (1) NL300752I2 (enExample)
NO (3) NO334316B1 (enExample)
NZ (1) NZ542910A (enExample)
PL (2) PL2070526T3 (enExample)
PT (2) PT2070526E (enExample)
RU (1) RU2342929C2 (enExample)
SI (2) SI2070526T1 (enExample)
TW (1) TWI340640B (enExample)
WO (1) WO2004089353A2 (enExample)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
ATE317280T1 (de) * 2001-09-03 2006-02-15 Newron Pharm Spa Pharmazeutische zusammensetzung mit gabapentin oder deren analog und einem alpha-aminoamid und analgetische verwendung dieser zusammensetzung
EP1438956A1 (en) * 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
PT1658062E (pt) * 2003-08-25 2010-03-31 Newron Pharm Spa Derivados de alfa-amino amida úteis como agentes antiinflamatórios
EP1588704A1 (en) 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders
KR101277520B1 (ko) * 2004-09-10 2013-06-21 뉴론 파마슈티칼즈 에스. 피. 에이. (할로벤질옥시)벤질아미노-프로판아미드를 포함하는 선택적 나트륨 및/또는 칼슘 채널 조절제로서 유용한 약제학적 조성물
US20070004639A1 (en) * 2005-07-01 2007-01-04 Bodybio, Inc. Methods and compositions for treating Parkinson's disease
WO2007069274A2 (en) * 2005-11-09 2007-06-21 Torrent Pharmaceuticals Limited Pharmaceutical composition comprising a compound having a catechol moiety and an alkalising agent
NZ567540A (en) * 2005-12-22 2010-07-30 Newron Pharm Spa 2-Phenylethylamino derivatives as calcium and/or sodium channel modulators
CN101032474B (zh) * 2006-03-06 2011-02-16 重庆医药工业研究院有限责任公司 一种治疗或预防神经系统疾病的雷沙吉兰透皮贴片及其制备方法
EP1870097A1 (en) * 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of cognitive disorders
US8106056B2 (en) * 2006-06-16 2012-01-31 Solvay Pharmaceuticals B.V. Combination preparations comprising bifeprunox and a dopamine agonist
EA025326B1 (ru) * 2006-06-19 2016-12-30 Ньюрон Фармасьютикалс С.П.А. Применение сафинамида и ралфинамида высокой степени чистоты для лечения заболеваний и болезненных состояний в условиях, не препятствующих активности цитохромов системы cyp450 и не проявляющих блокирующих свойств в отношении herg канала
DE102007014947B4 (de) * 2007-03-23 2010-05-27 Axxonis Pharma Ag Stabilisierte wässrige Lösungen von Ergolinverbindungen
JP2010525018A (ja) * 2007-04-24 2010-07-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング プラミペキソール又はその医薬的に許容できる塩を含有する徐放性錠剤型製剤との組成物
AU2008261325B2 (en) * 2007-06-15 2012-12-06 Newron Pharmaceuticals S.P.A. Substituted 2- [2- (phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel modulators
GB2453770A (en) * 2007-10-19 2009-04-22 Reckitt Benckiser Healthcare Oral composition comprising a cooling agent
US20090149544A1 (en) * 2007-10-22 2009-06-11 Concert Pharmaceuticals, Inc. Alpha-aminoamide derivatives
CN101896456B (zh) 2007-12-11 2014-10-22 纽朗制药有限公司 具有高纯度的2-[4-(3-或2-氟苄氧基)苄氨基]丙酰胺类的生产方法
EA019529B1 (ru) * 2007-12-19 2014-04-30 Ньюрон Фармасьютикалс С.П.А. Альфа-аминоамидные производные, применяемые в лечении психиатрических расстройств
US20110027354A1 (en) * 2008-04-01 2011-02-03 Kim Hyoung-Chun Anti-parkinsonian compounds
NZ589486A (en) * 2008-06-02 2012-08-31 Generics Uk Ltd A process for the preparation of enantiomerically pure 1-(R)-(2-propynylamino)indan
CA2723870C (en) * 2008-06-02 2015-04-21 Generics [Uk] Limited An improved process for the preparation of amines
RU2540470C9 (ru) * 2008-06-06 2015-07-20 Фарма Ту Б Лтд. Фармацевтические композиции для лечения болезни паркинсона
CN102065687A (zh) * 2008-06-13 2011-05-18 泰华制药工业有限公司 雷沙吉兰用于改善帕金森氏症
WO2010010138A1 (en) * 2008-07-24 2010-01-28 Boehringer Ingelheim International Gmbh Pharmaceutical composition comprising pramipexole and a calcium channel blocker for the treatment of parkinson's disease
US20100189791A1 (en) * 2009-01-23 2010-07-29 Teva Pharmaceutical Industries, Ltd. Delayed release rasagiline malate formulation
EP2218444A3 (en) * 2009-01-23 2010-08-25 Teva Pharmaceutical Industries, Ltd. Delayed release rasagiline formulation
EP2314569A1 (en) 2009-10-22 2011-04-27 Merck Patent GmbH Novel polymorphic forms of (S)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-propionamide mesylate salt and processes of manufacturing thereof
CN102048717B (zh) 2009-10-29 2014-02-19 重庆医药工业研究院有限责任公司 一种稳定的雷沙吉兰组合物
WO2011098456A1 (en) 2010-02-09 2011-08-18 Merck Serono S.A. Safinamide in the treatment of dyskinesia
KR101851118B1 (ko) 2010-04-27 2018-04-23 뉴론 파마슈티칼즈 에스. 피. 에이. 랄핀아미드 메탄설포네이트 염들 또는 이들의 r―에난티오머들의 제조 방법
US9017723B2 (en) 2010-04-30 2015-04-28 Teikoku Pharma Usa, Inc. Propynylaminoindan transdermal compositions
WO2012129429A2 (en) 2011-03-24 2012-09-27 Teikoku Pharma Usa, Inc. Transdermal compositions comprising an active agent layer and an active agent conversion layer
US20150031768A1 (en) * 2011-08-19 2015-01-29 The Trustees Of Princeton University C-halogen bond formation
US10196341B2 (en) 2011-08-19 2019-02-05 The Trustees Of Princeton University C-halogen bond formation
WO2013070526A1 (en) 2011-11-09 2013-05-16 Teikoku Pharma Usa, Inc. Methods for the treatment of skin neoplasms
MX390106B (es) 2012-10-22 2025-03-20 Merz Pharmaceuticals Llc Formulaciones de levodopa para el alivio rapido de la enfermedad de parkinson
NZ706590A (en) 2012-11-02 2016-02-26 Teikoku Pharma Usa Inc Propynylaminoindan transdermal compositions
US9155695B2 (en) 2013-03-14 2015-10-13 Medtronic, Inc. Injectable ropinirole compositions and methods for making and using same
US10111879B2 (en) 2013-06-27 2018-10-30 Cedars-Sinai Medical Center Adrenoceptors antagonists for the prevention and treatment of neurodegenerative conditions
SG11201608608PA (en) * 2014-04-21 2016-11-29 Civitas Therapeutics Inc Rapid relief of motor fluctuations in parkinson's disease
US10676425B2 (en) 2014-10-02 2020-06-09 Megabiowood Co., Ltd Alpha-aminoamide derivative compound and pharmaceutical composition comprising same
RS59651B1 (sr) * 2015-08-27 2020-01-31 Prexton Therapeutics Sa Derivat hromonoksima koji prodire u mozak u svrhu terapije diskinezije uzrokovane levodopom
KR102889062B1 (ko) * 2016-03-17 2025-11-21 더 존스 홉킨스 유니버시티 Paris의 파네실화에 의해 파킨슨병을 예방 또는 치료하기 위한 방법
ITUA20163981A1 (it) 2016-05-31 2017-12-01 Zambon Spa Composizioni farmaceutiche comprendenti safinamide
WO2018132746A1 (en) * 2017-01-14 2018-07-19 Mischley Laurie Kathern Method of using human excrement and secretions for early detection of parkinson's disease
CN109251155A (zh) * 2017-07-14 2019-01-22 广东东阳光药业有限公司 α-氨基酰胺衍生物及其用途
CA3072994A1 (en) * 2017-08-17 2019-02-21 Zi-Qiang Gu Pamoate salt of monoamine anti-parkinson's agents, method of preparation and use thereof
EA202091127A1 (ru) 2017-11-02 2020-09-22 Замбон С.П.А. Фармацевтические композиции, включающие сафинамид
KR102005019B1 (ko) * 2018-04-04 2019-07-31 한국과학기술연구원 뇌졸중의 예방 및 치료용 조성물
CN119564619A (zh) * 2019-09-12 2025-03-07 阿奇维生命科学公司 治疗和/或预防有需要的受试者的成瘾的包括野靛碱的组合物
LU101477B1 (en) * 2019-11-12 2021-05-14 Univ Luxembourg An inhibitor of an iron-containing hydrogenase of a methanogenic archaeon for use in the treatment or prevention of a parkinsonian condition
CN110938014A (zh) * 2019-11-28 2020-03-31 岳千奥 取代苯氧酰胺衍生物、应用及用于治疗帕金森病的药物
CN112915083A (zh) * 2019-12-06 2021-06-08 上海医药集团股份有限公司 药物组合物、成套药盒及其应用
CN110999980A (zh) * 2019-12-19 2020-04-14 新疆石河子职业技术学院(石河子市技工学校) 一种葡萄酒洗浸奶酪加工方法
US20230181508A1 (en) * 2020-08-31 2023-06-15 Purdue Pharma L.P. Compositions and methods for levodopa delivery
KR20230154249A (ko) * 2021-03-08 2023-11-07 프로테나 바이오사이언시즈 리미티드 파킨슨 질환의 치료
KR102790040B1 (ko) * 2021-06-24 2025-04-01 연세대학교 산학협력단 도파민 미모톱 기능 합성 펩티드 및 이를 포함하는 mao-b 억제제

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1140748A (en) 1966-06-23 1969-01-22 Ici Ltd New carboxylic acid derivatives
US3795739A (en) * 1972-02-14 1974-03-05 Hoffmann La Roche Treatment of parkinson disease
US4049663A (en) 1972-06-06 1977-09-20 Allen & Hanburys Limited Ethylene diamine derivatives
FR2480747A1 (fr) 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique
US4935429A (en) 1985-10-25 1990-06-19 Dackis Charles A Method of treating psychostimulant addiction
DE252290T1 (de) * 1986-06-10 1988-06-09 Chiesi Farmaceutici S.P.A., Parma Levodopa-methyl-ester enthaltende pharmazeutische zusammensetzungen, ihre herstellung und therapeutische verwendungen.
EP0331620B1 (de) 1988-03-01 1993-08-11 Birkmayer, Walther, Prof. Dr. Mittel zur Behandlung des Parkinson-Syndroms
IL94466A (en) 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation
US5221536A (en) * 1990-05-07 1993-06-22 Alza Corporation Dosage form indicated for the management of abnormal posture, tremor and involuntary movement
US5502658A (en) 1990-12-27 1996-03-26 Relin; Arkadi Sampled-continuous probability method of velocity measurement of the object having informatively-structural inhomogeneity
GB9306886D0 (en) 1993-04-01 1993-05-26 Erba Carlo Spa Substituted (arylakoxybenzyl) aminopropanamide derivatives and process for their preparation
IL111240A (en) * 1993-10-18 2001-10-31 Teva Pharma Salts of r(+) - enantiomers of n- propargyl-1-aminoindan and pharmaceutical compositions comprising them
US6258827B1 (en) * 1995-05-26 2001-07-10 Pfizer Inc. Combinations for the treatment of parkinsonism containing selective NMDA antagonists
GB9515412D0 (en) * 1995-07-27 1995-09-27 Pharmacia Spa 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives
GB9727523D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
FI109453B (fi) 1999-06-30 2002-08-15 Orion Yhtymae Oyj Farmaseuttinen koostumus
US20020019421A1 (en) * 2000-07-05 2002-02-14 Roni Biberman Compositions and therapy for substance addiction
DE10041479A1 (de) * 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923
FR2829027A1 (fr) * 2001-08-29 2003-03-07 Aventis Pharma Sa Association avec un antagoniste du recepteur cb1, les compositions pharmaceutiques les contenant et leur utilisation pour le traitement de la maladie de parkinson

Also Published As

Publication number Publication date
US8283380B2 (en) 2012-10-09
SI1613296T1 (sl) 2009-10-31
EP2070526B1 (en) 2014-02-26
WO2004089353A8 (en) 2005-09-01
CN102274517A (zh) 2011-12-14
PT2070526E (pt) 2014-03-31
WO2004089353A3 (en) 2004-12-16
ES2454272T3 (es) 2014-04-10
JP2006522800A (ja) 2006-10-05
IL216403A0 (en) 2011-12-29
JP2013067647A (ja) 2013-04-18
NO335537B1 (no) 2014-12-22
NO20131417L (no) 2005-12-09
DE602004021790D1 (de) 2009-08-13
EP1613296A2 (en) 2006-01-11
NO334316B1 (no) 2014-02-03
FR15C0054I1 (fr) 2015-11-09
CY1109295T1 (el) 2014-07-02
RU2005131422A (ru) 2006-04-27
CA2523188A1 (en) 2004-10-21
CA2523188C (en) 2012-09-25
IL216403A (en) 2015-01-29
KR20060010745A (ko) 2006-02-02
RU2342929C2 (ru) 2009-01-10
KR101129015B1 (ko) 2012-04-20
PL2070526T3 (pl) 2014-08-29
MXPA05010873A (es) 2006-03-21
AU2004228782A1 (en) 2004-10-21
PL1613296T3 (pl) 2009-12-31
TWI340640B (en) 2011-04-21
US20130053368A1 (en) 2013-02-28
PT1613296E (pt) 2009-07-30
WO2004089353A2 (en) 2004-10-21
CY1115286T1 (el) 2017-01-04
AU2004228782B2 (en) 2010-05-20
US8901176B2 (en) 2014-12-02
CY2015025I2 (el) 2016-04-13
DK2070526T3 (da) 2014-03-24
US9492410B2 (en) 2016-11-15
CN102274517B (zh) 2018-08-31
LU92782I2 (fr) 2015-09-22
ATE435012T1 (de) 2009-07-15
BRPI0409364A (pt) 2006-04-25
HUS1500043I1 (hu) 2018-11-28
DK1613296T3 (da) 2009-10-05
NL300752I2 (enExample) 2016-07-05
CY2015025I1 (el) 2016-04-13
NO20054640L (no) 2005-12-09
US20070093495A1 (en) 2007-04-26
EP1613296B1 (en) 2009-07-01
IL171331A (en) 2012-03-29
TW200505423A (en) 2005-02-16
NO20054640D0 (no) 2005-10-10
NO2015018I2 (no) 2015-07-23
NZ542910A (en) 2007-10-26
AR044007A1 (es) 2005-08-24
NO2015018I1 (no) 2015-08-03
EP2070526A1 (en) 2009-06-17
US20150150833A1 (en) 2015-06-04
ES2326373T3 (es) 2009-10-08
CN1771030A (zh) 2006-05-10
KR20110070929A (ko) 2011-06-24
SI2070526T1 (sl) 2014-05-30

Similar Documents

Publication Publication Date Title
FR15C0054I2 (fr) Procedes de traitement de la maladie de parkinson
EP1643986A4 (en) PHENYL ACARBOXYLATE BETA SECRETASE INHIBITORS FOR THE TREATMENT OF MORBUS ALZHEIMER
EP1636359A4 (en) PROCESS FOR PAIN TREATMENT
EP1656359A4 (en) MACROCYCLIC BETA-SEKRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER DISEASE
EP2166854A4 (en) TRIAZONE DERIVATIVES FOR THE TREATMENT OF MORBUS ALZHEIMER AND RELATED SUFFERINGS
EP1838714A4 (en) METHOD FOR TREATING PAIN
EP2312945A4 (en) PURE DERIVATIVES FOR THE TREATMENT OF MORBUS ALZHEIMER
EP2001503A4 (en) DIAGNOSIS AND TREATMENT OF MORBUS ALZHEIMER
EP1565187A4 (en) METHOD FOR THE TREATMENT OF CANCER AND RELATED METHODS
EP1755584A4 (en) Treatment of myopia
EP1870051A4 (en) MEDICAL THERAPY DEVICE
EP1910829A4 (en) PREVENTION AND TREATMENT OF SYNUCLEINOPATHIC AND AMYLOIDOGEN DISEASES
EP1776136A4 (en) TREATMENT OF DEMYELINISING DISEASES
EP2198292A4 (en) IMPROVED MORBUS ALZHEIMER DIAGNOSIS
ATE443704T1 (de) Pyridopyrimidinone zur behandlung von krebserkrankungen
EP1817050A4 (en) DIAGNOSIS AND TREATMENT OF MORBUS ALZHEIMER
EP1855679A4 (en) AMINOMETHYL-BETA-SEKRETASE-INHIBITOR FOR THE TREATMENT OF ALZHEIMER
EP1838330A4 (en) TREATMENT OF SOLID TUMORS
EP2379075A4 (en) TRIAZOL DERIVATIVES FOR THE TREATMENT OF ALZHEIMER DISEASE
EP2059235A4 (en) METHOD FOR THE PREVENTION AND TREATMENT OF ALZHEIMER DISEASE
EP2375895A4 (en) METHOD FOR THE TREATMENT OF MORBUS ALZHEIMER AND RELATED SUFFERINGS
EP2061442A4 (en) TREATMENT, PREVENTION AND REVERSAL OF ALCOHOL-INDUCED BRAIN DISEASES
EP2182976A4 (en) TREATMENT OF AUTOIMMUNE DISEASES
EP1858499A4 (en) METHOD FOR TREATING DEGENERATIVE NETWORK DISEASE
EP1948210A4 (en) METHOD FOR TREATING ISCHEMIC HEART DISEASE