FI965074A - Tropan-2-aldoxinderivat som inhibitorer för återupptagning av signalsubstans - Google Patents

Tropan-2-aldoxinderivat som inhibitorer för återupptagning av signalsubstans Download PDF

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Publication number
FI965074A
FI965074A FI965074A FI965074A FI965074A FI 965074 A FI965074 A FI 965074A FI 965074 A FI965074 A FI 965074A FI 965074 A FI965074 A FI 965074A FI 965074 A FI965074 A FI 965074A
Authority
FI
Finland
Prior art keywords
pct
inhibitors
aldoxine
tropane
derivatives
Prior art date
Application number
FI965074A
Other languages
English (en)
Finnish (fi)
Other versions
FI965074A0 (sv
Inventor
Peter Moldt
Frank Watjen
Jorgen Scheel-Krueger
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Publication of FI965074A0 publication Critical patent/FI965074A0/sv
Publication of FI965074A publication Critical patent/FI965074A/sv

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Addiction (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
FI965074A 1994-04-19 1996-12-17 Tropan-2-aldoxinderivat som inhibitorer för återupptagning av signalsubstans FI965074A (sv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK44794 1994-04-19
DK133894 1994-11-24
PCT/EP1995/001358 WO1995028401A1 (en) 1994-04-19 1995-04-12 Tropane-2-aldoxine derivatives as neurotransmitter reuptake inhibitors

Publications (2)

Publication Number Publication Date
FI965074A0 FI965074A0 (sv) 1996-12-17
FI965074A true FI965074A (sv) 1996-12-17

Family

ID=26064021

Family Applications (1)

Application Number Title Priority Date Filing Date
FI965074A FI965074A (sv) 1994-04-19 1996-12-17 Tropan-2-aldoxinderivat som inhibitorer för återupptagning av signalsubstans

Country Status (25)

Country Link
US (1) US5736556A (sv)
EP (1) EP0756596B1 (sv)
JP (1) JP2899418B2 (sv)
KR (1) KR100210417B1 (sv)
CN (1) CN1043763C (sv)
AT (1) ATE222587T1 (sv)
AU (1) AU690257B2 (sv)
BG (1) BG63259B1 (sv)
BR (1) BR9507489A (sv)
CA (1) CA2187309C (sv)
CZ (1) CZ284379B6 (sv)
DE (1) DE69527839T2 (sv)
DK (1) DK0756596T3 (sv)
EE (1) EE03877B1 (sv)
FI (1) FI965074A (sv)
GE (1) GEP19991749B (sv)
HU (1) HU215830B (sv)
LV (1) LV11738B (sv)
NO (1) NO964180L (sv)
NZ (1) NZ284075A (sv)
PL (1) PL183025B1 (sv)
RU (1) RU2134264C1 (sv)
SK (1) SK280875B6 (sv)
UA (1) UA49801C2 (sv)
WO (1) WO1995028401A1 (sv)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3462505B2 (ja) * 1995-10-13 2003-11-05 ノイロサーチ アクティーゼルスカブ ８−アザビシクロ［３．２．１］オクト−２−エン誘導体、それらの製造及び使用
US6241963B1 (en) * 1995-10-19 2001-06-05 The Trustees Of The University Of Pennsylvania Dopamine and serotonin transporter ligands and imaging agents
ATE224392T1 (de) * 1995-11-02 2002-10-15 Neurosearch As Kondensierte tropanderivate als neurotransmitter- reuptake-inhibitoren
US5948933A (en) 1997-07-11 1999-09-07 Organix, Inc. Tropane analogs and methods for inhibition of monoamine transport
CA2244773C (en) 1996-02-22 2006-01-03 Neurosearch A/S Tropane-derivatives, their preparation and use
US6232326B1 (en) 1998-07-14 2001-05-15 Jodi A. Nelson Treatment for schizophrenia and other dopamine system dysfunctions
US20040229908A1 (en) * 1999-07-13 2004-11-18 Jodi Nelson Compositions and methods for the treatment of Parkinson's disease and tardive dyskinesias
EP1261340B1 (en) 1999-07-13 2009-05-13 Alpha Research Group, LLC Compositions and methods for the treatment of parkinson's disease
ES2401812T3 (es) * 2000-05-26 2013-04-24 Pfizer Inc. Derivados de triazolil tropano como moduladores de CCR5
US6667314B2 (en) 2000-05-26 2003-12-23 Pfizer, Inc. Tropane derivatives useful in therapy
US20040106643A1 (en) * 2001-05-23 2004-06-03 Gouliaev Alex Haarh Tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
US6610849B2 (en) * 2001-06-28 2003-08-26 Boehringer Ingelheim Pharma Kg Process for the manufacture of tropenol
WO2003045388A1 (en) * 2001-11-30 2003-06-05 Neurosearch A/S Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases
DE10200943A1 (de) * 2002-01-12 2003-07-24 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Scopinestern
CA2480742A1 (en) * 2002-03-28 2003-12-04 President And Fellows Of Harvard College Tropane compounds
JP4874107B2 (ja) 2003-10-03 2012-02-15 ファイザー・インク Ｈｉｖ及び炎症の治療のためのｃｃｒ５受容体拮抗活性を有するイミダゾピリジン置換トロパン誘導体
EP2269608A3 (en) 2003-10-16 2011-02-16 NeuroSearch AS Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and an acetylcholinesterase inhibitor
CA2553649A1 (en) * 2004-01-22 2005-08-04 Neurosearch A/S Compounds for the sustained reduction of body weight
AU2005205882A1 (en) * 2004-01-22 2005-08-04 Neurosearch A/S Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and an N-methyl-D-aspartate (NMDA) receptors antagonist
RU2352332C1 (ru) * 2005-01-14 2009-04-20 Частное Предприятие "Славянская Клиника" Применение местного анестетика для коррекции пищевого поведения человека и способ применения
EP1779851A1 (en) 2005-10-31 2007-05-02 Boehringer Ingelheim Pharma GmbH & Co.KG Treatment of diabetes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU672052B2 (en) * 1992-12-23 1996-09-19 Neurosearch A/S Antidepressant and antiparkinsonian compounds
AU671163B2 (en) * 1992-12-23 1996-08-15 Neurosearch A/S Alkyl substituted heterocyclic compounds

Also Published As

Publication number Publication date
BG100883A (en) 1998-03-31
CA2187309C (en) 2000-11-21
FI965074A0 (sv) 1996-12-17
CN1148854A (zh) 1997-04-30
US5736556A (en) 1998-04-07
CZ284379B6 (cs) 1998-11-11
RU2134264C1 (ru) 1999-08-10
AU690257B2 (en) 1998-04-23
EE03877B1 (et) 2002-10-15
JPH09505607A (ja) 1997-06-03
MX9604966A (es) 1998-05-31
CZ298296A3 (en) 1997-06-11
JP2899418B2 (ja) 1999-06-02
DE69527839T2 (de) 2003-01-02
HU9602707D0 (en) 1996-11-28
PL183025B1 (pl) 2002-05-31
DK0756596T3 (da) 2002-12-23
NO964180D0 (no) 1996-10-02
SK280875B6 (sk) 2000-08-14
BG63259B1 (bg) 2001-07-31
CN1043763C (zh) 1999-06-23
UA49801C2 (uk) 2002-10-15
AU2257595A (en) 1995-11-10
BR9507489A (pt) 1997-08-12
WO1995028401A1 (en) 1995-10-26
ATE222587T1 (de) 2002-09-15
SK128896A3 (en) 1997-04-09
NO964180L (no) 1996-12-16
NZ284075A (en) 1998-01-26
LV11738A (lv) 1997-04-20
HU215830B (hu) 2001-05-28
HUT75865A (en) 1997-05-28
PL316876A1 (en) 1997-02-17
LV11738B (en) 1997-12-20
DE69527839D1 (en) 2002-09-26
EE9600132A (et) 1997-04-15
KR100210417B1 (ko) 1999-07-15
EP0756596B1 (en) 2002-08-21
GEP19991749B (en) 1999-09-10
CA2187309A1 (en) 1995-10-26
EP0756596A1 (en) 1997-02-05

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