ATE224392T1 - Kondensierte tropanderivate als neurotransmitter- reuptake-inhibitoren - Google Patents
Kondensierte tropanderivate als neurotransmitter- reuptake-inhibitorenInfo
- Publication number
- ATE224392T1 ATE224392T1 AT96938064T AT96938064T ATE224392T1 AT E224392 T1 ATE224392 T1 AT E224392T1 AT 96938064 T AT96938064 T AT 96938064T AT 96938064 T AT96938064 T AT 96938064T AT E224392 T1 ATE224392 T1 AT E224392T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- alkynyl
- alkenyl
- aryl
- arylalkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Exhaust Gas After Treatment (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK122395 | 1995-11-02 | ||
DK14696 | 1996-02-13 | ||
PCT/EP1996/004793 WO1997016451A1 (en) | 1995-11-02 | 1996-11-04 | Fused tropane-derivatives as neurotransmitter reuptake inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE224392T1 true ATE224392T1 (de) | 2002-10-15 |
Family
ID=26063395
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96938064T ATE224392T1 (de) | 1995-11-02 | 1996-11-04 | Kondensierte tropanderivate als neurotransmitter- reuptake-inhibitoren |
Country Status (25)
Country | Link |
---|---|
US (1) | US5998405A (de) |
EP (1) | EP0858461B1 (de) |
JP (1) | JP3157839B2 (de) |
KR (1) | KR100277482B1 (de) |
CN (1) | CN1060775C (de) |
AT (1) | ATE224392T1 (de) |
AU (1) | AU702720B2 (de) |
BR (1) | BR9611300A (de) |
CA (1) | CA2236707C (de) |
CZ (1) | CZ285571B6 (de) |
DE (1) | DE69623799T2 (de) |
DK (1) | DK0858461T3 (de) |
EE (1) | EE03566B1 (de) |
HK (1) | HK1016984A1 (de) |
HU (1) | HUP9802534A3 (de) |
IL (1) | IL123898A (de) |
IS (1) | IS4708A (de) |
NO (1) | NO309569B1 (de) |
NZ (1) | NZ321970A (de) |
PL (1) | PL184843B1 (de) |
RU (1) | RU2162469C2 (de) |
SK (1) | SK282944B6 (de) |
TR (1) | TR199800780T2 (de) |
UA (1) | UA47442C2 (de) |
WO (1) | WO1997016451A1 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6706880B2 (en) | 1990-08-09 | 2004-03-16 | Research Triangle Institute | Cocaine receptor binding ligands |
US6329520B1 (en) | 1990-08-09 | 2001-12-11 | Research Triangle Institute | Cocaine receptor binding ligands |
US6150376A (en) * | 1998-08-05 | 2000-11-21 | Georgetown University | Bi- and tri-cyclic aza compounds and their uses |
YU13301A (sh) * | 1998-08-18 | 2005-06-10 | Ucb S.A. | Muskarinski agonisti i antagonisti |
WO2001023385A2 (en) * | 1999-09-27 | 2001-04-05 | Georgetown University | Novel tropane analogs |
US6479509B1 (en) | 2000-05-22 | 2002-11-12 | Research Triangle Institute | Method of promoting smoking cessation |
AU2001265820A1 (en) * | 2000-07-04 | 2002-01-14 | Neurosearch A/S | Steric isomers of fused tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
US7160899B2 (en) | 2001-04-09 | 2007-01-09 | Neurosearch A/S | Adenosine A2A receptor antangonists combined with neurotrophic activity compounds in the treatment of Parkinson's disease |
WO2002094827A1 (en) * | 2001-05-23 | 2002-11-28 | Neurosearch A/S | Fused tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
AR035898A1 (es) | 2001-05-25 | 2004-07-21 | Wyeth Corp | Aril-8-azabiciclo[3.2.1]octanos, un proceso para su preparacion, una formulacion y el uso de dichos compuestos para la manufactura de un medicamento para el tratamiento de la depresion |
WO2003045388A1 (en) * | 2001-11-30 | 2003-06-05 | Neurosearch A/S | Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases |
JP2006517568A (ja) | 2003-02-12 | 2006-07-27 | ニューロサーチ、アクティーゼルスカブ | 8−アザ−ビシクロ[3.2.1]オクタン誘導体及びこれをモノアミン神経伝達物質再取り込み阻害薬として使用する方法 |
JP2006517567A (ja) | 2003-02-12 | 2006-07-27 | ニューロサーチ、アクティーゼルスカブ | 新規8−アザ−ビシクロ[3.2.1]オクタン誘導体及びこれをモノアミン神経伝達物質再取り込み阻害薬として使用する方法 |
WO2006108789A1 (en) | 2005-04-08 | 2006-10-19 | Neurosearch A/S | Novel enantiomers and their use as monoamine neurotransmitter re-uptake inhibitors |
US7943630B2 (en) | 2005-06-28 | 2011-05-17 | Neurosearch A/S | 3,9-diaza-spiro[5.5]undecane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
US8093388B2 (en) | 2005-06-28 | 2012-01-10 | Neurosearch A/S | 3-aza spiro[5,5]undec-8-ene derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
TW200800980A (en) | 2006-02-17 | 2008-01-01 | Neurosearch As | Novel compounds |
RU2011143972A (ru) | 2009-05-15 | 2013-06-20 | НьюроСёрч А/С | Производные хромен-2-она и их применение в качестве ингибиторов обратного захвата моноаминовых нейромедиаторов |
RU2549551C2 (ru) * | 2009-06-19 | 2015-04-27 | Эббви Инк. | Производные диазагомоадамантана и способы их применения |
WO2011032903A1 (en) | 2009-09-21 | 2011-03-24 | Neurosearch A/S | Piperazinyl-alkyl-benzoimidazol-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
WO2011092061A1 (en) | 2010-01-29 | 2011-08-04 | Neurosearch A/S | Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
WO2011117289A1 (en) | 2010-03-25 | 2011-09-29 | Neurosearch A/S | Chromen-2-one derivatives and their use as monoamine neuro-transmitter re-uptake inhibitors |
WO2012000881A1 (en) | 2010-07-02 | 2012-01-05 | Neurosearch A/S | Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
JP6052524B1 (ja) * | 2015-07-30 | 2016-12-27 | 秋夫 湯田 | 持ち運び設置が容易な手提げハンドルの付いた薪ストーブ。 |
WO2024008808A1 (en) | 2022-07-08 | 2024-01-11 | Initiator Pharma A/S | Compound for treatment of female sexual dysfunction |
WO2024089247A1 (en) | 2022-10-28 | 2024-05-02 | Initiator Pharma A/S | Compound for treatment of pain |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU672644B2 (en) * | 1992-12-23 | 1996-10-10 | Neurosearch A/S | Aryl substituted heterocyclic compounds |
SK280875B6 (sk) * | 1994-04-19 | 2000-08-14 | Neurosearch A/S | Tropánové deriváty, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a použitie týchto derivátov na výrobu liečiv |
-
1996
- 1996-11-04 AT AT96938064T patent/ATE224392T1/de not_active IP Right Cessation
- 1996-11-04 RU RU98110007/04A patent/RU2162469C2/ru not_active IP Right Cessation
- 1996-11-04 TR TR1998/00780T patent/TR199800780T2/xx unknown
- 1996-11-04 EP EP96938064A patent/EP0858461B1/de not_active Expired - Lifetime
- 1996-11-04 WO PCT/EP1996/004793 patent/WO1997016451A1/en active IP Right Grant
- 1996-11-04 BR BR9611300A patent/BR9611300A/pt not_active Application Discontinuation
- 1996-11-04 CZ CZ981138A patent/CZ285571B6/cs not_active IP Right Cessation
- 1996-11-04 HU HU9802534A patent/HUP9802534A3/hu unknown
- 1996-11-04 CA CA002236707A patent/CA2236707C/en not_active Expired - Fee Related
- 1996-11-04 AU AU75631/96A patent/AU702720B2/en not_active Ceased
- 1996-11-04 DE DE69623799T patent/DE69623799T2/de not_active Expired - Lifetime
- 1996-11-04 IL IL12389896A patent/IL123898A/en not_active IP Right Cessation
- 1996-11-04 NZ NZ321970A patent/NZ321970A/en unknown
- 1996-11-04 UA UA98041933A patent/UA47442C2/uk unknown
- 1996-11-04 EE EE9800100A patent/EE03566B1/xx not_active IP Right Cessation
- 1996-11-04 US US09/051,107 patent/US5998405A/en not_active Expired - Lifetime
- 1996-11-04 SK SK422-98A patent/SK282944B6/sk unknown
- 1996-11-04 CN CN96198012A patent/CN1060775C/zh not_active Expired - Fee Related
- 1996-11-04 PL PL96326448A patent/PL184843B1/pl unknown
- 1996-11-04 DK DK96938064T patent/DK0858461T3/da active
- 1996-11-04 KR KR1019980702592A patent/KR100277482B1/ko not_active IP Right Cessation
- 1996-11-04 JP JP51708397A patent/JP3157839B2/ja not_active Expired - Fee Related
-
1998
- 1998-03-31 IS IS4708A patent/IS4708A/is unknown
- 1998-04-07 NO NO981609A patent/NO309569B1/no unknown
-
1999
- 1999-05-24 HK HK99102261A patent/HK1016984A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE224392T1 (de) | Kondensierte tropanderivate als neurotransmitter- reuptake-inhibitoren | |
UA49872C2 (uk) | Похідні тропану, спосіб їх одержання, фармацевтична композиція та спосіб лікування | |
NO980919D0 (no) | 8-azabicyklo(3.2.1)okt-2-ene derivater, deres fremstilling og anvendelse | |
BG100883A (en) | Tropane-2-aldoxine derivatives as neurotransmitter reuptake inhibitors | |
PE20011212A1 (es) | Compuestos para el tratamiento de la fibromialgia y el sindrome de fatiga cronica | |
HUP0201356A2 (hu) | Ösztrogén agonisták/antagonisták alkalmazása depresszió kezelésére vagy a kognitív funkció romlásának megelőzésére alkalmas gyógyászati készítmény előállítására | |
DE69433984D1 (de) | Arylpiperazinderivate von indol als liganden der rezeptoren 5 ht1-like, 5 ht1b und 5 ht1d | |
DE69817557D1 (de) | Piperidine derivate als inhibitoren der neurotransmitter-wiederaufbaunahme | |
JO2235B1 (en) | Derivatives of phenyl | |
DK1054885T3 (da) | Benzisoxasolderivater med D4-antagonistisk virkning | |
CA2437006A1 (en) | Aminotriazolopyridine derivatives as adenosine receptor ligands | |
HUP9802568A2 (hu) | Glutamát-receptor antagonista hatású szubsztituált-kinoxalin-2,3-dionok alkil-amin-származékai és ezeket tartalmazó gyógyszerkészítmények |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 0858461 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |