IS4708A - Samtengdar trópan-afleiður, framleiðsla þeirra ognotkun - Google Patents

Samtengdar trópan-afleiður, framleiðsla þeirra ognotkun

Info

Publication number
IS4708A
IS4708A IS4708A IS4708A IS4708A IS 4708 A IS4708 A IS 4708A IS 4708 A IS4708 A IS 4708A IS 4708 A IS4708 A IS 4708A IS 4708 A IS4708 A IS 4708A
Authority
IS
Iceland
Prior art keywords
alkyl
alkynyl
alkenyl
aryl
arylalkyl
Prior art date
Application number
IS4708A
Other languages
English (en)
Inventor
Scheel-Krüger Jørgen
M. Olsen Gunnar
østergaard Nielsen Elsbet
Hugo Dahl Bjarne
Helth Jensen Leif
Original Assignee
Neurosearch A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch A/S filed Critical Neurosearch A/S
Publication of IS4708A publication Critical patent/IS4708A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Exhaust Gas After Treatment (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IS4708A 1995-11-02 1998-03-31 Samtengdar trópan-afleiður, framleiðsla þeirra ognotkun IS4708A (is)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK122395 1995-11-02
DK14696 1996-02-13
PCT/EP1996/004793 WO1997016451A1 (en) 1995-11-02 1996-11-04 Fused tropane-derivatives as neurotransmitter reuptake inhibitors

Publications (1)

Publication Number Publication Date
IS4708A true IS4708A (is) 1998-03-31

Family

ID=26063395

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4708A IS4708A (is) 1995-11-02 1998-03-31 Samtengdar trópan-afleiður, framleiðsla þeirra ognotkun

Country Status (25)

Country Link
US (1) US5998405A (is)
EP (1) EP0858461B1 (is)
JP (1) JP3157839B2 (is)
KR (1) KR100277482B1 (is)
CN (1) CN1060775C (is)
AT (1) ATE224392T1 (is)
AU (1) AU702720B2 (is)
BR (1) BR9611300A (is)
CA (1) CA2236707C (is)
CZ (1) CZ285571B6 (is)
DE (1) DE69623799T2 (is)
DK (1) DK0858461T3 (is)
EE (1) EE03566B1 (is)
HK (1) HK1016984A1 (is)
HU (1) HUP9802534A3 (is)
IL (1) IL123898A (is)
IS (1) IS4708A (is)
NO (1) NO309569B1 (is)
NZ (1) NZ321970A (is)
PL (1) PL184843B1 (is)
RU (1) RU2162469C2 (is)
SK (1) SK282944B6 (is)
TR (1) TR199800780T2 (is)
UA (1) UA47442C2 (is)
WO (1) WO1997016451A1 (is)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6706880B2 (en) 1990-08-09 2004-03-16 Research Triangle Institute Cocaine receptor binding ligands
US6329520B1 (en) 1990-08-09 2001-12-11 Research Triangle Institute Cocaine receptor binding ligands
US6150376A (en) * 1998-08-05 2000-11-21 Georgetown University Bi- and tri-cyclic aza compounds and their uses
SK1892001A3 (en) * 1998-08-18 2001-11-06 Ucb Sa Muscarinic agonists and antagonists, pharmaceutical composition them comprising and use thereof
EP1220854A2 (en) 1999-09-27 2002-07-10 University Georgetown Novel tropane analogs
US6479509B1 (en) 2000-05-22 2002-11-12 Research Triangle Institute Method of promoting smoking cessation
WO2002002559A1 (en) * 2000-07-04 2002-01-10 Neurosearch A/S Steric isomers of fused tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
WO2002080957A1 (en) 2001-04-09 2002-10-17 Neurosearch A/S Adenosine a2a receptor antagonists combined with neurotrophic activity compounds in the treatment of parkinson's disease
WO2002094827A1 (en) * 2001-05-23 2002-11-28 Neurosearch A/S Fused tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
TW589312B (en) 2001-05-25 2004-06-01 Wyeth Corp Aryl-8-azabicyclo[3.2.1]octanes for the treatment of depression
US7381733B2 (en) 2001-11-30 2008-06-03 Neurosearch A/S Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases
AU2004212165B2 (en) 2003-02-12 2010-02-18 Neurosearch A/S Novel 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
WO2004072071A1 (en) 2003-02-12 2004-08-26 Neurosearch A/S 8-aza-bicyclo (3.2.1) octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
EP2272847A1 (en) 2005-04-08 2011-01-12 NeuroSearch A/S Enantiomers and their use as monoamine neurotransmitter re-uptake inhibitors
US8093388B2 (en) 2005-06-28 2012-01-10 Neurosearch A/S 3-aza spiro[5,5]undec-8-ene derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
WO2007000463A1 (en) * 2005-06-28 2007-01-04 Neurosearch A/S Novel 3,9-diaza-spiro[5.5]undecane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
TW200800980A (en) 2006-02-17 2008-01-01 Neurosearch As Novel compounds
WO2010130620A1 (en) 2009-05-15 2010-11-18 Neurosearch A/S Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
NZ597511A (en) * 2009-06-19 2014-01-31 Abbvie Inc Diazahomoadamantane derivatives and methods of use thereof
WO2011032903A1 (en) 2009-09-21 2011-03-24 Neurosearch A/S Piperazinyl-alkyl-benzoimidazol-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
WO2011092061A1 (en) 2010-01-29 2011-08-04 Neurosearch A/S Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
WO2011117289A1 (en) 2010-03-25 2011-09-29 Neurosearch A/S Chromen-2-one derivatives and their use as monoamine neuro-transmitter re-uptake inhibitors
WO2012000881A1 (en) 2010-07-02 2012-01-05 Neurosearch A/S Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
JP6052524B1 (ja) * 2015-07-30 2016-12-27 秋夫 湯田 持ち運び設置が容易な手提げハンドルの付いた薪ストーブ。
TW202409027A (zh) 2022-07-08 2024-03-01 丹麥商創始人製藥股份有限公司 用於女性性功能障礙的治療之化合物
WO2024089247A1 (en) 2022-10-28 2024-05-02 Initiator Pharma A/S Compound for treatment of pain
WO2024146892A1 (en) 2023-01-03 2024-07-11 Initiator Pharma A/S Compound for treatment of erectile dysfunction

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU672644B2 (en) * 1992-12-23 1996-10-10 Neurosearch A/S Aryl substituted heterocyclic compounds
UA49801C2 (uk) * 1994-04-19 2002-10-15 Нейросерч А/С Похідні тропан-2-альдоксиму, спосіб їх отримання, фармацевтична композиція, спосіб лікування

Also Published As

Publication number Publication date
KR19990064111A (ko) 1999-07-26
EP0858461A1 (en) 1998-08-19
MX9803554A (es) 1998-09-30
HK1016984A1 (en) 1999-11-12
CA2236707A1 (en) 1997-05-09
EE9800100A (et) 1998-10-15
DK0858461T3 (da) 2003-01-27
CZ285571B6 (cs) 1999-09-15
NO309569B1 (no) 2001-02-19
HUP9802534A2 (hu) 1999-04-28
JP3157839B2 (ja) 2001-04-16
HUP9802534A3 (en) 1999-06-28
EP0858461B1 (en) 2002-09-18
DE69623799T2 (de) 2003-01-30
TR199800780T2 (xx) 1998-07-21
IL123898A0 (en) 1998-10-30
SK42298A3 (en) 1998-10-07
US5998405A (en) 1999-12-07
CZ113898A3 (cs) 1998-07-15
NZ321970A (en) 2000-02-28
PL326448A1 (en) 1998-09-28
BR9611300A (pt) 1999-06-15
CN1201461A (zh) 1998-12-09
JPH11514638A (ja) 1999-12-14
ATE224392T1 (de) 2002-10-15
CA2236707C (en) 2002-08-06
RU2162469C2 (ru) 2001-01-27
WO1997016451A1 (en) 1997-05-09
AU7563196A (en) 1997-05-22
IL123898A (en) 2001-08-08
AU702720B2 (en) 1999-03-04
EE03566B1 (et) 2001-12-17
NO981609D0 (no) 1998-04-07
DE69623799D1 (de) 2002-10-24
UA47442C2 (uk) 2002-07-15
SK282944B6 (sk) 2003-01-09
NO981609L (no) 1998-06-26
KR100277482B1 (ko) 2001-01-15
CN1060775C (zh) 2001-01-17
PL184843B1 (pl) 2002-12-31

Similar Documents

Publication Publication Date Title
IS4708A (is) Samtengdar trópan-afleiður, framleiðsla þeirra ognotkun
UA49872C2 (uk) Похідні тропану, спосіб їх одержання, фармацевтична композиція та спосіб лікування
ATE362931T1 (de) 8-azabicyclo(3.2.1)oct-2en-derivate, deren herstellung und anwendung
MY114679A (en) Aroyl-piperidine derivatives
UA49801C2 (uk) Похідні тропан-2-альдоксиму, спосіб їх отримання, фармацевтична композиція, спосіб лікування
HUP0201356A2 (hu) Ösztrogén agonisták/antagonisták alkalmazása depresszió kezelésére vagy a kognitív funkció romlásának megelőzésére alkalmas gyógyászati készítmény előállítására
SE0101579D0 (sv) New compounds
JO2235B1 (en) Derivatives of phenyl
DE69817557D1 (de) Piperidine derivate als inhibitoren der neurotransmitter-wiederaufbaunahme
AU3327399A (en) Benzisoxazole derivatives having d4-antagonistic activity
CA2437006A1 (en) Aminotriazolopyridine derivatives as adenosine receptor ligands
HUP9802568A2 (hu) Glutamát-receptor antagonista hatású szubsztituált-kinoxalin-2,3-dionok alkil-amin-származékai és ezeket tartalmazó gyógyszerkészítmények