|
US5800992A
(en)
|
1989-06-07 |
1998-09-01 |
Fodor; Stephen P.A. |
Method of detecting nucleic acids
|
|
EP0834576B1
(en)
|
1990-12-06 |
2002-01-16 |
Affymetrix, Inc. (a Delaware Corporation) |
Detection of nucleic acid sequences
|
|
US5605798A
(en)
*
|
1993-01-07 |
1997-02-25 |
Sequenom, Inc. |
DNA diagnostic based on mass spectrometry
|
|
GB9315847D0
(en)
|
1993-07-30 |
1993-09-15 |
Isis Innovation |
Tag reagent and assay method
|
|
JPH09505729A
(ja)
*
|
1993-09-27 |
1997-06-10 |
アーチ・デヴェロップメント・コーポレイション |
核酸配列の効率的な決定のための方法と組成物
|
|
US6401267B1
(en)
|
1993-09-27 |
2002-06-11 |
Radoje Drmanac |
Methods and compositions for efficient nucleic acid sequencing
|
|
US6015880A
(en)
*
|
1994-03-16 |
2000-01-18 |
California Institute Of Technology |
Method and substrate for performing multiple sequential reactions on a matrix
|
|
US5679773A
(en)
*
|
1995-01-17 |
1997-10-21 |
Affymax Technologies N.V |
Reagants and methods for immobilized polymer synthesis and display
|
|
DE69531545T2
(de)
*
|
1994-06-23 |
2004-06-24 |
Affymax Technologies N.V., Willemstad |
Photolabile verbindungen und verfahren für deren verwendung
|
|
US5604097A
(en)
*
|
1994-10-13 |
1997-02-18 |
Spectragen, Inc. |
Methods for sorting polynucleotides using oligonucleotide tags
|
|
US6974666B1
(en)
|
1994-10-21 |
2005-12-13 |
Appymetric, Inc. |
Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
|
|
US5891742A
(en)
*
|
1995-01-19 |
1999-04-06 |
Chiron Corporation |
Affinity selection of ligands by mass spectroscopy
|
|
GB9504598D0
(en)
*
|
1995-03-03 |
1995-04-26 |
Imp Cancer Res Tech |
Method of nucleic acid analysis
|
|
GB9507238D0
(en)
*
|
1995-04-07 |
1995-05-31 |
Isis Innovation |
Detecting dna sequence variations
|
|
US5750341A
(en)
*
|
1995-04-17 |
1998-05-12 |
Lynx Therapeutics, Inc. |
DNA sequencing by parallel oligonucleotide extensions
|
|
US5624711A
(en)
*
|
1995-04-27 |
1997-04-29 |
Affymax Technologies, N.V. |
Derivatization of solid supports and methods for oligomer synthesis
|
|
US5830655A
(en)
|
1995-05-22 |
1998-11-03 |
Sri International |
Oligonucleotide sizing using cleavable primers
|
|
GB9517661D0
(en)
*
|
1995-08-30 |
1995-11-01 |
Smithkline Beecham Plc |
Novel compounds
|
|
US5780231A
(en)
*
|
1995-11-17 |
1998-07-14 |
Lynx Therapeutics, Inc. |
DNA extension and analysis with rolling primers
|
|
US5763175A
(en)
*
|
1995-11-17 |
1998-06-09 |
Lynx Therapeutics, Inc. |
Simultaneous sequencing of tagged polynucleotides
|
|
EP0962464A3
(en)
*
|
1996-01-23 |
2004-02-11 |
Qiagen Genomics, Inc. |
Methods and compositions for detecting binding of ligand pair using non-fluorescent label
|
|
CZ218398A3
(cs)
*
|
1996-01-23 |
1998-12-16 |
Rapigene, Inc. |
Způsoby a kompozice pro zjištění vaznosti ligandových párů za použití nefluoreskujícího značení
|
|
PT868535E
(pt)
*
|
1996-01-23 |
2000-12-29 |
Qiagen Genomics Inc |
Metodos e composicoes para a determinacao de sequencias de moleculas de acido nucleico
|
|
EP0992511B1
(en)
|
1996-01-23 |
2009-03-11 |
Operon Biotechnologies, Inc. |
Methods and compositions for determining the sequence of nucleic acid molecules
|
|
US6613508B1
(en)
|
1996-01-23 |
2003-09-02 |
Qiagen Genomics, Inc. |
Methods and compositions for analyzing nucleic acid molecules utilizing sizing techniques
|
|
US6027890A
(en)
*
|
1996-01-23 |
2000-02-22 |
Rapigene, Inc. |
Methods and compositions for enhancing sensitivity in the analysis of biological-based assays
|
|
US6312893B1
(en)
|
1996-01-23 |
2001-11-06 |
Qiagen Genomics, Inc. |
Methods and compositions for determining the sequence of nucleic acid molecules
|
|
JP2000503845A
(ja)
*
|
1996-01-23 |
2000-04-04 |
ラピジーン,インコーポレイテッド |
サイジング技術を用いる核酸分子の分析のための方法および組成物
|
|
CA2248084A1
(en)
*
|
1996-03-04 |
1997-09-12 |
Genetrace Systems, Inc. |
Methods of screening nucleic acids using mass spectrometry
|
|
US6475807B1
(en)
*
|
1996-04-08 |
2002-11-05 |
Smithkline Beecham Corporation |
Mass-based encoding and qualitative analysis of combinatorial libraries
|
|
ES2288760T3
(es)
|
1996-04-25 |
2008-01-16 |
Bioarray Solutions Ltd. |
Ensamblaje electrocinetico controlado por luz de particulas proximas a superficies.
|
|
US5958342A
(en)
*
|
1996-05-17 |
1999-09-28 |
Incyte Pharmaceuticals, Inc. |
Jet droplet device
|
|
US5965363A
(en)
*
|
1996-09-19 |
1999-10-12 |
Genetrace Systems Inc. |
Methods of preparing nucleic acids for mass spectrometric analysis
|
|
US5777324A
(en)
*
|
1996-09-19 |
1998-07-07 |
Sequenom, Inc. |
Method and apparatus for maldi analysis
|
|
WO1998012559A1
(en)
|
1996-09-20 |
1998-03-26 |
Demers James P |
Spatially addressable combinatorial chemical arrays in cd-rom format
|
|
US20030129589A1
(en)
|
1996-11-06 |
2003-07-10 |
Hubert Koster |
Dna diagnostics based on mass spectrometry
|
|
CA2274587A1
(en)
|
1996-12-10 |
1998-06-18 |
Genetrace Systems Inc. |
Releasable nonvolatile mass-label molecules
|
|
US6699668B1
(en)
*
|
1997-01-15 |
2004-03-02 |
Xzillion Gmbh & Co. |
Mass label linked hybridisation probes
|
|
AU728805B2
(en)
*
|
1997-01-15 |
2001-01-18 |
Xzillion Gmbh & Co. Kg |
Nucleic acid sequencing
|
|
EP1400599B1
(en)
*
|
1997-01-15 |
2007-10-03 |
Xzillion GmbH & CO.KG |
Mass label linked hybridisation probes
|
|
GB9707980D0
(en)
*
|
1997-04-21 |
1997-06-11 |
Brax Genomics Ltd |
Characterising DNA
|
|
GB9714716D0
(en)
*
|
1997-07-11 |
1997-09-17 |
Brax Genomics Ltd |
Characterising nucleic acids
|
|
EP0994968A1
(en)
|
1997-07-11 |
2000-04-26 |
Brax Group Limited |
Characterising nucleic acid
|
|
US7056659B1
(en)
|
1997-07-11 |
2006-06-06 |
Xzillion Gmbh & Co. |
Characterizing nucleic acids
|
|
AU736776B2
(en)
|
1997-07-22 |
2001-08-02 |
Qiagen Genomics, Inc. |
Apparatus and methods for arraying solution onto a solid support
|
|
EP0990047B1
(en)
*
|
1997-07-22 |
2003-05-14 |
Qiagen Genomics, Inc. |
Methods and compositions for analyzing nucleic acids by mass spectrometry
|
|
NZ501917A
(en)
|
1997-07-22 |
2001-10-26 |
Qiagen Genomics Inc |
Method and apparatus for enzymatic reactions performed on nucleic acid arrays conducted at dew point
|
|
HUP0002518A3
(en)
*
|
1997-07-22 |
2003-01-28 |
Qiagen Genomics Inc |
Computer method and system for correlating sequencing data by ms
|
|
GB9718921D0
(en)
*
|
1997-09-05 |
1997-11-12 |
Brax Genomics Ltd |
Catalytically generated mass labels
|
|
US6607878B2
(en)
*
|
1997-10-06 |
2003-08-19 |
Stratagene |
Collections of uniquely tagged molecules
|
|
US6101946A
(en)
*
|
1997-11-21 |
2000-08-15 |
Telechem International Inc. |
Microarray printing device including printing pins with flat tips and exterior channel and method of manufacture
|
|
DK1036202T3
(da)
*
|
1997-12-05 |
2002-08-12 |
Max Planck Gesellschaft |
Fremgangsmåde til identifikation af nucleinsyrer ved matriksassisteret laserdesorptions/ionisationsmassespektrometri
|
|
US6207861B1
(en)
|
1998-01-05 |
2001-03-27 |
Neogenesis, Inc. |
Method for producing and screening mass coded combinatorial libraries for drug discovery and target validation
|
|
EP1728776A3
(en)
*
|
1998-01-05 |
2006-12-13 |
Neogenesis, Inc. |
Method for identifying a member of a mass-coded combinatorial library
|
|
EP2241541A1
(en)
*
|
1998-01-05 |
2010-10-20 |
Neogenesis, Inc. |
Method for identifying a member of a mass-coded combinatorial library
|
|
US6265163B1
(en)
*
|
1998-01-09 |
2001-07-24 |
Lynx Therapeutics, Inc. |
Solid phase selection of differentially expressed genes
|
|
US6562567B2
(en)
|
1998-01-27 |
2003-05-13 |
California Institute Of Technology |
Method of detecting a nucleic acid
|
|
CA2332862A1
(en)
|
1998-05-15 |
1999-11-25 |
Isis Innovation Ltd. |
Libraries of oligomers labelled with different tags
|
|
US6104028A
(en)
|
1998-05-29 |
2000-08-15 |
Genetrace Systems Inc. |
Volatile matrices for matrix-assisted laser desorption/ionization mass spectrometry
|
|
US7399844B2
(en)
*
|
1998-07-09 |
2008-07-15 |
Agilent Technologies, Inc. |
Method and reagents for analyzing the nucleotide sequence of nucleic acids
|
|
US6218118B1
(en)
*
|
1998-07-09 |
2001-04-17 |
Agilent Technologies, Inc. |
Method and mixture reagents for analyzing the nucleotide sequence of nucleic acids by mass spectrometry
|
|
US5998175A
(en)
*
|
1998-07-24 |
1999-12-07 |
Lumigen, Inc. |
Methods of synthesizing and amplifying polynucleotides by ligation of multiple oligomers
|
|
US6232067B1
(en)
*
|
1998-08-17 |
2001-05-15 |
The Perkin-Elmer Corporation |
Adapter directed expression analysis
|
|
US20040242521A1
(en)
*
|
1999-10-25 |
2004-12-02 |
Board Of Regents, The University Of Texas System |
Thio-siRNA aptamers
|
|
US6423493B1
(en)
*
|
1998-10-26 |
2002-07-23 |
Board Of Regents The University Of Texas System |
Combinatorial selection of oligonucleotide aptamers
|
|
JP2003527075A
(ja)
*
|
1999-03-25 |
2003-09-16 |
ハイセック,インコーポレーテッド |
ハイブリダイゼーションによる配列分析のための、溶液ベースの方法
|
|
WO2000060116A1
(en)
*
|
1999-04-02 |
2000-10-12 |
Tropix, Inc. |
High throughput and high sensitivity detection assays
|
|
US7211390B2
(en)
*
|
1999-09-16 |
2007-05-01 |
454 Life Sciences Corporation |
Method of sequencing a nucleic acid
|
|
US7244559B2
(en)
*
|
1999-09-16 |
2007-07-17 |
454 Life Sciences Corporation |
Method of sequencing a nucleic acid
|
|
JP3668075B2
(ja)
*
|
1999-10-12 |
2005-07-06 |
光夫 板倉 |
遺伝物質シーケンス決定用懸濁系、その懸濁系を用いた遺伝物質シーケンス決定方法およびその懸濁系を用いたSNPs高速スコアリング方法
|
|
US7582420B2
(en)
|
2001-07-12 |
2009-09-01 |
Illumina, Inc. |
Multiplex nucleic acid reactions
|
|
US20040014102A1
(en)
*
|
2000-02-22 |
2004-01-22 |
Shiping Chen |
High density parallel printing of microarrays
|
|
AU4322801A
(en)
|
2000-02-22 |
2001-09-03 |
Genospectra, Inc. |
Microarray fabrication techniques and apparatus
|
|
CA2399189A1
(en)
|
2000-02-22 |
2001-08-30 |
Genospectra, Inc. |
Microarray fabrication techniques and apparatus
|
|
GB0006141D0
(en)
|
2000-03-14 |
2000-05-03 |
Brax Group Ltd |
Mass labels
|
|
DE10021204A1
(de)
*
|
2000-04-25 |
2001-11-08 |
Epigenomics Ag |
Verfahren zur hochparallelen Analyse von Polymorphismen
|
|
US20030190609A1
(en)
*
|
2000-06-08 |
2003-10-09 |
White P. Scott |
Address/capture tags for flow-cytometery based minisequencing
|
|
ATE423221T1
(de)
|
2000-06-13 |
2009-03-15 |
Univ Boston |
Verwendung von mass-matched nukleotide in der analyse von oligonukleotidmischungen sowie in der hoch-multiplexen nukleinsäuresequenzierung
|
|
US9709559B2
(en)
|
2000-06-21 |
2017-07-18 |
Bioarray Solutions, Ltd. |
Multianalyte molecular analysis using application-specific random particle arrays
|
|
DE60117556T2
(de)
|
2000-06-21 |
2006-11-02 |
Bioarray Solutions Ltd. |
Multianalytische molekularanalyse durch verwendung anwendungsspezifischer zufallspartikelarrays
|
|
US6680203B2
(en)
*
|
2000-07-10 |
2004-01-20 |
Esperion Therapeutics, Inc. |
Fourier transform mass spectrometry of complex biological samples
|
|
US20060057565A1
(en)
*
|
2000-09-11 |
2006-03-16 |
Jingyue Ju |
Combinatorial fluorescence energy transfer tags and uses thereof
|
|
US6627748B1
(en)
|
2000-09-11 |
2003-09-30 |
The Trustees Of Columbia University In The City Of New York |
Combinatorial fluorescence energy transfer tags and their applications for multiplex genetic analyses
|
|
DE60127162T2
(de)
*
|
2000-10-06 |
2008-04-24 |
The Trustees Of Columbia University In The City Of New York |
Massives Parallelverfahren zur Dekodierung von DNA und RNA
|
|
EP2072526B1
(en)
|
2000-10-06 |
2012-05-30 |
Novozymes, Inc. |
Methods for disrupting a gene involved in PGA synthesis in Bacillus licheniformis
|
|
US9708358B2
(en)
|
2000-10-06 |
2017-07-18 |
The Trustees Of Columbia University In The City Of New York |
Massive parallel method for decoding DNA and RNA
|
|
US7635571B2
(en)
*
|
2000-12-07 |
2009-12-22 |
Siemens Healthcare Diagnostics Products Gmbh |
Amplified signal in binding assays
|
|
RU2195668C2
(ru)
*
|
2001-02-12 |
2002-12-27 |
Мешандин Алексей Гаврилович |
Способ постановки реакции агглютинационного иммунологического анализа
|
|
US20040121310A1
(en)
*
|
2002-12-18 |
2004-06-24 |
Ecker David J. |
Methods for rapid detection and identification of bioagents in forensic studies
|
|
US20040121311A1
(en)
|
2002-12-06 |
2004-06-24 |
Ecker David J. |
Methods for rapid detection and identification of bioagents in livestock
|
|
US20040121314A1
(en)
*
|
2002-12-06 |
2004-06-24 |
Ecker David J. |
Methods for rapid detection and identification of bioagents in containers
|
|
US7226739B2
(en)
|
2001-03-02 |
2007-06-05 |
Isis Pharmaceuticals, Inc |
Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations
|
|
US7666588B2
(en)
|
2001-03-02 |
2010-02-23 |
Ibis Biosciences, Inc. |
Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
|
|
US20030027135A1
(en)
|
2001-03-02 |
2003-02-06 |
Ecker David J. |
Method for rapid detection and identification of bioagents
|
|
US7718354B2
(en)
*
|
2001-03-02 |
2010-05-18 |
Ibis Biosciences, Inc. |
Methods for rapid identification of pathogens in humans and animals
|
|
ATE335754T1
(de)
*
|
2001-03-19 |
2006-09-15 |
Harvard College |
Entwicklung neuer molekularer funktionen
|
|
AU2002256060B2
(en)
*
|
2001-04-03 |
2006-12-07 |
Thermo Finnigan Llc |
Methods and kits useful for the simplification of complex peptide mixtures
|
|
US7727713B2
(en)
|
2001-06-20 |
2010-06-01 |
Nuevolution A/S |
Templated molecules and methods for using such molecules
|
|
US7262063B2
(en)
|
2001-06-21 |
2007-08-28 |
Bio Array Solutions, Ltd. |
Directed assembly of functional heterostructures
|
|
US7217510B2
(en)
|
2001-06-26 |
2007-05-15 |
Isis Pharmaceuticals, Inc. |
Methods for providing bacterial bioagent characterizing information
|
|
US8073627B2
(en)
|
2001-06-26 |
2011-12-06 |
Ibis Biosciences, Inc. |
System for indentification of pathogens
|
|
US7402286B2
(en)
*
|
2001-06-27 |
2008-07-22 |
The Regents Of The University Of California |
Capillary pins for high-efficiency microarray printing device
|
|
US6855538B2
(en)
*
|
2001-06-27 |
2005-02-15 |
The Regents Of The University Of California |
High-efficiency microarray printing device
|
|
EP1417475A4
(en)
*
|
2001-07-06 |
2006-06-28 |
454 Corp |
METHOD FOR ISOLATING INDEPENDENT, PARALLEL CHEMICAL MICRORE ACTIONS USING A POROUS FILTER
|
|
US20030087309A1
(en)
*
|
2001-08-27 |
2003-05-08 |
Shiping Chen |
Desktop drug screening system
|
|
US10539561B1
(en)
|
2001-08-30 |
2020-01-21 |
Customarray, Inc. |
Enzyme-amplified redox microarray detection process
|
|
US20030054396A1
(en)
*
|
2001-09-07 |
2003-03-20 |
Weiner Michael P. |
Enzymatic light amplification
|
|
CA2460131C
(en)
*
|
2001-09-14 |
2006-11-21 |
Xzillion Gmbh & Co. Kg |
Mass labels
|
|
CA2741049C
(en)
*
|
2001-10-15 |
2019-02-05 |
Bioarray Solutions, Ltd. |
Multiplexed analysis of polymorphic loci by probe elongation-mediated detection
|
|
US20080138800A1
(en)
*
|
2001-10-15 |
2008-06-12 |
Alice Xiang Li |
Multiplexed analysis of polymorphic loci by concurrent interrogation and enzyme-mediated detection
|
|
US20050124022A1
(en)
*
|
2001-10-30 |
2005-06-09 |
Maithreyan Srinivasan |
Novel sulfurylase-luciferase fusion proteins and thermostable sulfurylase
|
|
US6956114B2
(en)
|
2001-10-30 |
2005-10-18 |
'454 Corporation |
Sulfurylase-luciferase fusion proteins and thermostable sulfurylase
|
|
US6902921B2
(en)
|
2001-10-30 |
2005-06-07 |
454 Corporation |
Sulfurylase-luciferase fusion proteins and thermostable sulfurylase
|
|
WO2003042697A1
(en)
*
|
2001-11-14 |
2003-05-22 |
Genospectra, Inc. |
Biochemical analysis system with combinatorial chemistry applications
|
|
US7057026B2
(en)
*
|
2001-12-04 |
2006-06-06 |
Solexa Limited |
Labelled nucleotides
|
|
GB0129012D0
(en)
|
2001-12-04 |
2002-01-23 |
Solexa Ltd |
Labelled nucleotides
|
|
GB0131014D0
(en)
|
2001-12-28 |
2002-02-13 |
James Peter |
Method for molecule-mlecule analysis
|
|
CA2518626A1
(en)
|
2002-03-15 |
2003-09-25 |
Nuevolution A/S |
An improved method for synthesising templated molecules
|
|
US9126165B1
(en)
|
2002-04-24 |
2015-09-08 |
The University Of North Carolina At Greensboro |
Nucleic acid arrays to monitor water and other ecosystems
|
|
US8383342B2
(en)
|
2002-04-24 |
2013-02-26 |
The University Of North Carolina At Greensboro |
Compositions, products, methods and systems to monitor water and other ecosystems
|
|
US8048623B1
(en)
|
2002-04-24 |
2011-11-01 |
The University Of North Carolina At Greensboro |
Compositions, products, methods and systems to monitor water and other ecosystems
|
|
US7214492B1
(en)
|
2002-04-24 |
2007-05-08 |
The University Of North Carolina At Greensboro |
Nucleic acid arrays to monitor water and other ecosystems
|
|
GB0210535D0
(en)
*
|
2002-05-08 |
2002-06-19 |
Novartis Ag |
Organic compounds
|
|
AU2003240436A1
(en)
*
|
2002-06-20 |
2004-01-06 |
Nuevolution A/S |
Microarrays displaying encoded molecules
|
|
US7074597B2
(en)
*
|
2002-07-12 |
2006-07-11 |
The Trustees Of Columbia University In The City Of New York |
Multiplex genotyping using solid phase capturable dideoxynucleotides and mass spectrometry
|
|
EP1539980B1
(en)
|
2002-08-01 |
2016-02-17 |
Nuevolution A/S |
Library of complexes comprising small non-peptide molecules and double-stranded oligonucleotides identifying the molecules
|
|
JP4657919B2
(ja)
*
|
2002-08-19 |
2011-03-23 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
進化する新しい分子機能
|
|
DK3002289T3
(en)
*
|
2002-08-23 |
2018-04-23 |
Illumina Cambridge Ltd |
MODIFIED NUCLEOTIDES FOR POLYNUCLEOTIDE SEQUENCE
|
|
US11008359B2
(en)
|
2002-08-23 |
2021-05-18 |
Illumina Cambridge Limited |
Labelled nucleotides
|
|
US7414116B2
(en)
|
2002-08-23 |
2008-08-19 |
Illumina Cambridge Limited |
Labelled nucleotides
|
|
CA2749227A1
(en)
*
|
2002-10-16 |
2005-01-13 |
Board Of Regents Of The University Of Texas System |
Bead bound combinatorial oligonucleoside phosphorothioate and phosphorodithioate aptamer libraries
|
|
CN106337046B
(zh)
|
2002-10-30 |
2021-03-23 |
纽韦卢森公司 |
合成双功能复合物的方法
|
|
US20040091850A1
(en)
*
|
2002-11-08 |
2004-05-13 |
Travis Boone |
Single cell analysis of membrane molecules
|
|
AU2003298655A1
(en)
|
2002-11-15 |
2004-06-15 |
Bioarray Solutions, Ltd. |
Analysis, secure access to, and transmission of array images
|
|
CA2508726A1
(en)
|
2002-12-06 |
2004-07-22 |
Isis Pharmaceuticals, Inc. |
Methods for rapid identification of pathogens in humans and animals
|
|
WO2004055160A2
(en)
*
|
2002-12-13 |
2004-07-01 |
The Trustees Of Columbia University In The City Of New York |
Biomolecular coupling methods using 1,3-dipolar cycloaddition chemistry
|
|
EP1756277B1
(en)
|
2002-12-19 |
2009-12-02 |
Nuevolution A/S |
Quasirandom structure and function guided synthesis methods
|
|
AU2004209426B2
(en)
|
2003-01-29 |
2008-04-17 |
454 Life Sciences Corporation |
Method for preparing single-stranded DNA libraries
|
|
US7575865B2
(en)
*
|
2003-01-29 |
2009-08-18 |
454 Life Sciences Corporation |
Methods of amplifying and sequencing nucleic acids
|
|
JP2004235111A
(ja)
*
|
2003-01-31 |
2004-08-19 |
Ebara Corp |
イオン伝導体及びその製造方法
|
|
WO2004074429A2
(en)
|
2003-02-21 |
2004-09-02 |
Nuevolution A/S |
Method for producing second-generation library
|
|
EP1608748B1
(en)
|
2003-03-20 |
2009-03-04 |
Nuevolution A/S |
Ligational encoding of small molecules
|
|
GB0306756D0
(en)
*
|
2003-03-24 |
2003-04-30 |
Xzillion Gmbh & Co Kg |
Mass labels
|
|
US8017323B2
(en)
*
|
2003-03-26 |
2011-09-13 |
President And Fellows Of Harvard College |
Free reactant use in nucleic acid-templated synthesis
|
|
US20050233390A1
(en)
*
|
2003-04-09 |
2005-10-20 |
Allen John W |
Device including a proteinaceous factor, a recombinant proteinaceous factor, and a nucleotide sequence encoding the proteinaceous factor
|
|
US8046171B2
(en)
|
2003-04-18 |
2011-10-25 |
Ibis Biosciences, Inc. |
Methods and apparatus for genetic evaluation
|
|
US8057993B2
(en)
|
2003-04-26 |
2011-11-15 |
Ibis Biosciences, Inc. |
Methods for identification of coronaviruses
|
|
EP1623020A4
(en)
*
|
2003-05-09 |
2007-05-09 |
Sigma Aldrich Co |
GENOMIC AND PROTEOMIC APPROACHES FOR THE DEVELOPMENT OF A CELLULAR MEDIUM
|
|
US8158354B2
(en)
|
2003-05-13 |
2012-04-17 |
Ibis Biosciences, Inc. |
Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
|
|
US7964343B2
(en)
|
2003-05-13 |
2011-06-21 |
Ibis Biosciences, Inc. |
Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
|
|
US7910523B2
(en)
*
|
2003-05-23 |
2011-03-22 |
Board Of Regents, The University Of Texas System |
Structure based and combinatorially selected oligonucleoside phosphorothioate and phosphorodithioate aptamer targeting AP-1 transcription factors
|
|
EP1635693A2
(en)
*
|
2003-05-23 |
2006-03-22 |
Board Of Regents, The University Of Texas System |
High throughput screening of aptamer libraries for specific binding to proteins on viruses and other pathogens
|
|
WO2005003778A2
(en)
*
|
2003-07-02 |
2005-01-13 |
Nuevolution A/S |
A method for identifying a synthetic molecule having affinity towards a target
|
|
CA2533691A1
(en)
*
|
2003-07-24 |
2005-02-03 |
Board Of Regents The University Of Texas System |
Thioaptamers enable discovery of physiological pathways and new therapeutic strategies
|
|
GB0320059D0
(en)
*
|
2003-08-27 |
2003-10-01 |
Solexa Ltd |
A method of sequencing
|
|
US20050069895A1
(en)
*
|
2003-08-29 |
2005-03-31 |
Applera Corporation |
Compositions, methods, and kits for fabricating coded molecular tags
|
|
US20050048498A1
(en)
*
|
2003-08-29 |
2005-03-03 |
Applera Corporation |
Compositions, methods, and kits for assembling probes
|
|
US7198900B2
(en)
*
|
2003-08-29 |
2007-04-03 |
Applera Corporation |
Multiplex detection compositions, methods, and kits
|
|
US8546082B2
(en)
|
2003-09-11 |
2013-10-01 |
Ibis Biosciences, Inc. |
Methods for identification of sepsis-causing bacteria
|
|
US8288523B2
(en)
|
2003-09-11 |
2012-10-16 |
Ibis Biosciences, Inc. |
Compositions for use in identification of bacteria
|
|
US8097416B2
(en)
|
2003-09-11 |
2012-01-17 |
Ibis Biosciences, Inc. |
Methods for identification of sepsis-causing bacteria
|
|
US7927796B2
(en)
|
2003-09-18 |
2011-04-19 |
Bioarray Solutions, Ltd. |
Number coding for identification of subtypes of coded types of solid phase carriers
|
|
ATE447626T1
(de)
|
2003-09-18 |
2009-11-15 |
Nuevolution As |
Methode zur gewinnung struktureller informationen kodierter moleküle und zur selektion von verbindungen
|
|
ES2375962T3
(es)
|
2003-09-22 |
2012-03-07 |
Bioarray Solutions Ltd |
Polielectrolito inmovilizado en superficie con múltiples grupos funcionales capaces de unirse covalentemente a biomoléculas.
|
|
NZ547492A
(en)
|
2003-10-28 |
2009-12-24 |
Bioarray Solutions Ltd |
Optimization of gene expression analysis using immobilized capture probes of different lengths and densities
|
|
NZ547495A
(en)
|
2003-10-29 |
2008-05-30 |
Bioarray Solutions Ltd |
Multiplexed nucleic acid analysis by fragmentation of double-stranded DNA
|
|
US20050239102A1
(en)
*
|
2003-10-31 |
2005-10-27 |
Verdine Gregory L |
Nucleic acid binding oligonucleotides
|
|
US8163895B2
(en)
|
2003-12-05 |
2012-04-24 |
Ibis Biosciences, Inc. |
Compositions for use in identification of orthopoxviruses
|
|
EP1694693A2
(en)
*
|
2003-12-17 |
2006-08-30 |
Praecis Pharmaceuticals Inc. |
Methods for synthesis of encoded libraries
|
|
EP2287178A3
(en)
|
2004-01-09 |
2011-05-18 |
Novozymes, Inc. |
Bacillus licheniformis YvmC inactivation
|
|
US7666592B2
(en)
|
2004-02-18 |
2010-02-23 |
Ibis Biosciences, Inc. |
Methods for concurrent identification and quantification of an unknown bioagent
|
|
US8119336B2
(en)
|
2004-03-03 |
2012-02-21 |
Ibis Biosciences, Inc. |
Compositions for use in identification of alphaviruses
|
|
CA2557818A1
(en)
*
|
2004-03-03 |
2005-09-15 |
The Trustees Of Columbia University In The City Of New York |
Photocleavable fluorescent nucleotides for dna sequencing on chip constructed by site-specific coupling chemistry
|
|
WO2005090566A2
(en)
|
2004-03-22 |
2005-09-29 |
Nuevolution A/S |
Ligational encoding using building block oligonucleotides
|
|
US20050239134A1
(en)
*
|
2004-04-21 |
2005-10-27 |
Board Of Regents, The University Of Texas System |
Combinatorial selection of phosphorothioate single-stranded DNA aptamers for TGF-beta-1 protein
|
|
WO2006073436A2
(en)
*
|
2004-04-29 |
2006-07-13 |
The Trustees Of Columbia University In The City Of New York |
Mass tag pcr for multiplex diagnostics
|
|
WO2005117270A2
(en)
|
2004-05-24 |
2005-12-08 |
Isis Pharmaceuticals, Inc. |
Mass spectrometry with selective ion filtration by digital thresholding
|
|
US20050266411A1
(en)
|
2004-05-25 |
2005-12-01 |
Hofstadler Steven A |
Methods for rapid forensic analysis of mitochondrial DNA
|
|
US7811753B2
(en)
|
2004-07-14 |
2010-10-12 |
Ibis Biosciences, Inc. |
Methods for repairing degraded DNA
|
|
CA2575675A1
(en)
*
|
2004-07-30 |
2006-03-09 |
Adeza Biomedical Corporation |
Oncofetal fibronectin as a marker for disease and other conditions and methods for detection of oncofetal fibronectin
|
|
US7848889B2
(en)
|
2004-08-02 |
2010-12-07 |
Bioarray Solutions, Ltd. |
Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
|
|
US20060102471A1
(en)
|
2004-11-18 |
2006-05-18 |
Karl Maurer |
Electrode array device having an adsorbed porous reaction layer
|
|
EP2003214B1
(en)
|
2005-02-01 |
2013-04-10 |
AB Advanced Genetic Analysis Corporation |
Reagents, methods, and libraries for bead-based sequencing
|
|
US8182992B2
(en)
|
2005-03-03 |
2012-05-22 |
Ibis Biosciences, Inc. |
Compositions for use in identification of adventitious viruses
|
|
US8084207B2
(en)
|
2005-03-03 |
2011-12-27 |
Ibis Bioscience, Inc. |
Compositions for use in identification of papillomavirus
|
|
US20070034513A1
(en)
*
|
2005-03-25 |
2007-02-15 |
Combimatrix Corporation |
Electrochemical deblocking solution for electrochemical oligomer synthesis on an electrode array
|
|
US9394167B2
(en)
*
|
2005-04-15 |
2016-07-19 |
Customarray, Inc. |
Neutralization and containment of redox species produced by circumferential electrodes
|
|
US8486629B2
(en)
|
2005-06-01 |
2013-07-16 |
Bioarray Solutions, Ltd. |
Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
|
|
CA2611297A1
(en)
*
|
2005-06-07 |
2007-01-18 |
Universite Des Sciences Et Technologies De Lille |
Use of ionic matrices for maldi mass spectrometry analysis of tissue sections
|
|
US9169510B2
(en)
*
|
2005-06-21 |
2015-10-27 |
The Trustees Of Columbia University In The City Of New York |
Pyrosequencing methods and related compositions
|
|
EP1904655A2
(en)
|
2005-07-21 |
2008-04-02 |
Isis Pharmaceuticals, Inc. |
Methods for rapid identification and quantitation of nucleic acid variants
|
|
GB0515323D0
(en)
|
2005-07-26 |
2005-08-31 |
Electrophoretics Ltd |
Mass labels
|
|
GB0517097D0
(en)
|
2005-08-19 |
2005-09-28 |
Solexa Ltd |
Modified nucleosides and nucleotides and uses thereof
|
|
GB0518585D0
(en)
|
2005-09-12 |
2005-10-19 |
Electrophoretics Ltd |
Mass labels
|
|
US20070065877A1
(en)
|
2005-09-19 |
2007-03-22 |
Combimatrix Corporation |
Microarray having a base cleavable succinate linker
|
|
US8855955B2
(en)
*
|
2005-09-29 |
2014-10-07 |
Custom Array, Inc. |
Process and apparatus for measuring binding events on a microarray of electrodes
|
|
EP1957983A4
(en)
*
|
2005-11-21 |
2010-03-24 |
Univ Columbia |
DIGITAL MULTIPLEX IMMUNE PRESENCE USING A LIBRARY OF PHOTOSPARABLE MASS DAYS
|
|
US7889347B2
(en)
*
|
2005-11-21 |
2011-02-15 |
Plexera Llc |
Surface plasmon resonance spectrometer with an actuator driven angle scanning mechanism
|
|
ES2897529T3
(es)
|
2005-12-01 |
2022-03-01 |
Nuevolution As |
Métodos de codificación enzimática para la síntesis eficiente de bibliotecas grandes
|
|
US7463358B2
(en)
*
|
2005-12-06 |
2008-12-09 |
Lumera Corporation |
Highly stable surface plasmon resonance plates, microarrays, and methods
|
|
DK1991694T3
(da)
*
|
2006-02-13 |
2016-08-01 |
Fluidigm Canada Inc |
Genekspressionsanalyse med grundstoftagget oligonukleotid
|
|
US20090062129A1
(en)
*
|
2006-04-19 |
2009-03-05 |
Agencourt Personal Genomics, Inc. |
Reagents, methods, and libraries for gel-free bead-based sequencing
|
|
CN101495656B
(zh)
*
|
2006-06-07 |
2017-02-08 |
纽约哥伦比亚大学理事会 |
采用带修饰的核苷酸通过纳米通道进行dna序列测定
|
|
CA2663029C
(en)
|
2006-09-14 |
2016-07-19 |
Ibis Biosciences, Inc. |
Targeted whole genome amplification method for identification of pathogens
|
|
WO2008042067A2
(en)
|
2006-09-28 |
2008-04-10 |
Illumina, Inc. |
Compositions and methods for nucleotide sequencing
|
|
WO2008066931A2
(en)
|
2006-11-29 |
2008-06-05 |
Novozymes, Inc. |
Bacillus licheniformis chromosome
|
|
US7883869B2
(en)
|
2006-12-01 |
2011-02-08 |
The Trustees Of Columbia University In The City Of New York |
Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators
|
|
US8133701B2
(en)
*
|
2006-12-05 |
2012-03-13 |
Sequenom, Inc. |
Detection and quantification of biomolecules using mass spectrometry
|
|
US7902345B2
(en)
|
2006-12-05 |
2011-03-08 |
Sequenom, Inc. |
Detection and quantification of biomolecules using mass spectrometry
|
|
US7897737B2
(en)
|
2006-12-05 |
2011-03-01 |
Lasergen, Inc. |
3′-OH unblocked, nucleotides and nucleosides, base modified with photocleavable, terminating groups and methods for their use in DNA sequencing
|
|
US7893227B2
(en)
*
|
2006-12-05 |
2011-02-22 |
Lasergen, Inc. |
3′-OH unblocked nucleotides and nucleosides base modified with non-cleavable, terminating groups and methods for their use in DNA sequencing
|
|
US8871471B2
(en)
|
2007-02-23 |
2014-10-28 |
Ibis Biosciences, Inc. |
Methods for rapid forensic DNA analysis
|
|
GB0704764D0
(en)
|
2007-03-12 |
2007-04-18 |
Electrophoretics Ltd |
Isobarically labelled reagents and methods of their use
|
|
WO2008151023A2
(en)
|
2007-06-01 |
2008-12-11 |
Ibis Biosciences, Inc. |
Methods and compositions for multiple displacement amplification of nucleic acids
|
|
US9404150B2
(en)
|
2007-08-29 |
2016-08-02 |
Sequenom, Inc. |
Methods and compositions for universal size-specific PCR
|
|
US20090060786A1
(en)
*
|
2007-08-29 |
2009-03-05 |
Gibum Kim |
Microfluidic apparatus for wide area microarrays
|
|
EP2209911B1
(en)
|
2007-10-19 |
2013-10-16 |
The Trustees of Columbia University in the City of New York |
Dna sequencing with non-fluorescent nucleotide reversible terminators and cleavable label modified nucleotide terminators and a deoxyinosine analogue with a reversible terminator group
|
|
EP2940029B1
(en)
|
2007-10-19 |
2023-11-29 |
The Trustees of Columbia University in the City of New York |
Design and synthesis of cleavable fluorescent nucleotides as reversible terminators for dna sequencing by synthesis
|
|
GB0809488D0
(en)
|
2008-05-23 |
2008-07-02 |
Electrophoretics Ltd |
Mass spectrometric analysis
|
|
CN102264917B
(zh)
|
2008-06-11 |
2015-06-10 |
激光基因公司 |
核苷酸和核苷以及将其用于dna测序的方法
|
|
EP2347254A2
(en)
|
2008-09-16 |
2011-07-27 |
Ibis Biosciences, Inc. |
Sample processing units, systems, and related methods
|
|
US8534447B2
(en)
|
2008-09-16 |
2013-09-17 |
Ibis Biosciences, Inc. |
Microplate handling systems and related computer program products and methods
|
|
EP2349549B1
(en)
|
2008-09-16 |
2012-07-18 |
Ibis Biosciences, Inc. |
Mixing cartridges, mixing stations, and related kits, and system
|
|
EP2396803A4
(en)
|
2009-02-12 |
2016-10-26 |
Ibis Biosciences Inc |
IONIZATION PROBE ASSEMBLIES
|
|
DK3211126T3
(da)
|
2009-02-13 |
2020-12-21 |
X Chem Inc |
Fremgangsmåder til dannelse og screening af dna-kodede biblioteker
|
|
WO2010107946A2
(en)
*
|
2009-03-18 |
2010-09-23 |
Sequenom, Inc. |
Use of thermostable endonucleases for generating reporter molecules
|
|
WO2011008972A1
(en)
|
2009-07-17 |
2011-01-20 |
Ibis Biosciences, Inc. |
Systems for bioagent identification
|
|
WO2011008971A1
(en)
|
2009-07-17 |
2011-01-20 |
Ibis Biosciences, Inc. |
Lift and mount apparatus
|
|
WO2011032040A1
(en)
*
|
2009-09-10 |
2011-03-17 |
Centrillion Technology Holding Corporation |
Methods of targeted sequencing
|
|
US10174368B2
(en)
*
|
2009-09-10 |
2019-01-08 |
Centrillion Technology Holdings Corporation |
Methods and systems for sequencing long nucleic acids
|
|
EP3225695A1
(en)
|
2009-10-15 |
2017-10-04 |
Ibis Biosciences, Inc. |
Multiple displacement amplification
|
|
WO2011090793A2
(en)
|
2010-01-20 |
2011-07-28 |
Customarray, Inc. |
Multiplex microarray of serially deposited biomolecules on a microarray
|
|
US20110192723A1
(en)
*
|
2010-02-08 |
2011-08-11 |
Genia Technologies, Inc. |
Systems and methods for manipulating a molecule in a nanopore
|
|
US9678055B2
(en)
|
2010-02-08 |
2017-06-13 |
Genia Technologies, Inc. |
Methods for forming a nanopore in a lipid bilayer
|
|
US8324914B2
(en)
|
2010-02-08 |
2012-12-04 |
Genia Technologies, Inc. |
Systems and methods for characterizing a molecule
|
|
US9605307B2
(en)
|
2010-02-08 |
2017-03-28 |
Genia Technologies, Inc. |
Systems and methods for forming a nanopore in a lipid bilayer
|
|
WO2011127933A1
(en)
|
2010-04-16 |
2011-10-20 |
Nuevolution A/S |
Bi-functional complexes and methods for making and using such complexes
|
|
US9291597B2
(en)
|
2010-07-02 |
2016-03-22 |
Ventana Medical Systems, Inc. |
Detecting targets using mass tags and mass spectrometry
|
|
WO2012083249A2
(en)
|
2010-12-17 |
2012-06-21 |
The Trustees Of Columbia University In The City Of New York |
Dna sequencing by synthesis using modified nucleotides and nanopore detection
|
|
GB2500360B
(en)
|
2010-12-22 |
2019-10-23 |
Genia Tech Inc |
Nanopore-based single DNA molecule characterization, identification and isolation using speed bumps
|
|
US9581563B2
(en)
|
2011-01-24 |
2017-02-28 |
Genia Technologies, Inc. |
System for communicating information from an array of sensors
|
|
US9110478B2
(en)
|
2011-01-27 |
2015-08-18 |
Genia Technologies, Inc. |
Temperature regulation of measurement arrays
|
|
US9624539B2
(en)
|
2011-05-23 |
2017-04-18 |
The Trustees Of Columbia University In The City Of New York |
DNA sequencing by synthesis using Raman and infrared spectroscopy detection
|
|
MX360438B
(es)
|
2011-09-07 |
2018-11-01 |
X Chem Inc |
Metodos para etiquetar bibliotecas codificadas por adn.
|
|
MX342195B
(es)
|
2011-09-13 |
2016-09-20 |
Lasergen Inc |
Nucleótidos de terminación de rápida fotodescomposición 5-metoxi, 3' -oh no bloqueados y métodos para secuenciación de ácido nucleico.
|
|
US8986629B2
(en)
|
2012-02-27 |
2015-03-24 |
Genia Technologies, Inc. |
Sensor circuit for controlling, detecting, and measuring a molecular complex
|
|
ES2906186T3
(es)
|
2012-04-09 |
2022-04-13 |
Univ Columbia |
Método para la preparación de nanoporo y usos del mismo
|
|
EP2861768A4
(en)
|
2012-06-15 |
2016-03-02 |
Genia Technologies Inc |
CHIP SETUP AND HIGH ACCURACY NUCLEIC ACID SEQUENCING
|
|
WO2013191793A1
(en)
|
2012-06-20 |
2013-12-27 |
The Trustees Of Columbia University In The City Of New York |
Nucleic acid sequencing by nanopore detection of tag molecules
|
|
EP2872680B1
(en)
|
2012-07-13 |
2018-04-04 |
X-Chem, Inc. |
Dna-encoded libraries having encoding oligonucleotide linkages not readable by polymerases
|
|
US9605309B2
(en)
|
2012-11-09 |
2017-03-28 |
Genia Technologies, Inc. |
Nucleic acid sequencing using tags
|
|
US9759711B2
(en)
|
2013-02-05 |
2017-09-12 |
Genia Technologies, Inc. |
Nanopore arrays
|
|
CA2903095C
(en)
|
2013-03-15 |
2018-02-13 |
Xiaohai Liu |
Modified nucleosides or nucleotides
|
|
US10732183B2
(en)
|
2013-03-15 |
2020-08-04 |
The Trustees Of Columbia University In The City Of New York |
Method for detecting multiple predetermined compounds in a sample
|
|
WO2014144883A1
(en)
|
2013-03-15 |
2014-09-18 |
The Trustees Of Columbia University In The City Of New York |
Raman cluster tagged molecules for biological imaging
|
|
US9551697B2
(en)
|
2013-10-17 |
2017-01-24 |
Genia Technologies, Inc. |
Non-faradaic, capacitively coupled measurement in a nanopore cell array
|
|
US9567630B2
(en)
|
2013-10-23 |
2017-02-14 |
Genia Technologies, Inc. |
Methods for forming lipid bilayers on biochips
|
|
EP3640349A3
(en)
|
2013-10-23 |
2020-07-29 |
Roche Sequencing Solutions, Inc. |
High speed molecular sensing with nanopores
|
|
CN106715453B
(zh)
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