FI950888A - Menetelmä K-vitamiinista riippuvaisten proteiinien eristämiseksi ja puhdistamiseksi - Google Patents

Menetelmä K-vitamiinista riippuvaisten proteiinien eristämiseksi ja puhdistamiseksi Download PDF

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Publication number
FI950888A
FI950888A FI950888A FI950888A FI950888A FI 950888 A FI950888 A FI 950888A FI 950888 A FI950888 A FI 950888A FI 950888 A FI950888 A FI 950888A FI 950888 A FI950888 A FI 950888A
Authority
FI
Finland
Prior art keywords
isolating
vitamin
dependent proteins
proteins
dependent
Prior art date
Application number
FI950888A
Other languages
English (en)
Swedish (sv)
Other versions
FI950888A0 (fi
FI116526B (fi
Inventor
Bernhard Fischer
Artur Mitterer
Friedrich Dorner
Original Assignee
Immuno Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno Ag filed Critical Immuno Ag
Publication of FI950888A0 publication Critical patent/FI950888A0/fi
Publication of FI950888A publication Critical patent/FI950888A/fi
Application granted granted Critical
Publication of FI116526B publication Critical patent/FI116526B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/647—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6429—Thrombin (3.4.21.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21005—Thrombin (3.4.21.5)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI950888A 1994-02-28 1995-02-27 Menetelmä K-vitamiinista riippuvaisten proteiinien eristämiseksi ja puhdistamiseksi FI116526B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4406515A DE4406515C1 (de) 1994-02-28 1994-02-28 Verfahren zur Isolierung und Reinigung Vitamin K-abhängiger Proteine
DE4406515 1994-02-28

Publications (3)

Publication Number Publication Date
FI950888A0 FI950888A0 (fi) 1995-02-27
FI950888A true FI950888A (fi) 1995-08-29
FI116526B FI116526B (fi) 2005-12-15

Family

ID=6511421

Family Applications (1)

Application Number Title Priority Date Filing Date
FI950888A FI116526B (fi) 1994-02-28 1995-02-27 Menetelmä K-vitamiinista riippuvaisten proteiinien eristämiseksi ja puhdistamiseksi

Country Status (13)

Country Link
US (1) US5633350A (fi)
EP (1) EP0669342B1 (fi)
JP (1) JPH07258286A (fi)
AT (1) ATE205218T1 (fi)
CA (1) CA2143510C (fi)
CZ (1) CZ290471B6 (fi)
DE (1) DE4406515C1 (fi)
DK (1) DK0669342T3 (fi)
ES (1) ES2161790T3 (fi)
FI (1) FI116526B (fi)
HU (1) HU219828B (fi)
NO (1) NO322372B1 (fi)
SK (1) SK22695A3 (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3137699A (en) * 1998-04-15 1999-11-01 Novo Nordisk A/S Novel process for the separation of proteins using a Ca ++ containing eluant
DE60138111D1 (de) * 2000-07-21 2009-05-07 Chemo Sero Therapeut Res Inst Verfahren zur reinigung eines kalziumionen-bindenden proteins
US7897734B2 (en) 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
JP2008525381A (ja) * 2004-12-23 2008-07-17 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 関心のあるビタミンｋ依存性タンパク質を含んでなる組成物中におけるタンパク質混入物の量の減少
ATE476501T1 (de) * 2005-01-14 2010-08-15 Bayer Healthcare Llc Verfahren zur reinigung von factor vii
MX2007013156A (es) * 2005-04-28 2008-01-18 Novo Nordisk Healthcare Ag Envase cerrado que comprende un polipeptido del factor vii activado, procesos para la preparacion del mismo y kit y metodo para el uso del kit.
US7375084B2 (en) 2006-03-07 2008-05-20 Baxter International Inc. Highly phosphorylated and sulfated recombinant factor IX
EP2125866B1 (en) * 2007-02-28 2013-05-22 Baxter International Inc. Method for the purification of recombinant blood coagulation factor ix enriched in sulfated and/or phosphorylated molecules
EP2526115B1 (en) * 2010-01-18 2018-08-01 Novo Nordisk Health Care AG Purification of blood coagulation factors
ES2790884T3 (es) 2010-04-29 2020-10-29 Baxalta GmbH Método de purificación para proteínas de unión a cationes divalentes sobre resina de intercambio aniónico
MX342922B (es) 2011-02-01 2016-10-19 Novo Nordisk As Purificacion de insulina.
AU2012322949B2 (en) 2011-10-14 2015-07-02 Takeda Pharmaceutical Company Limited Protein purification by anion exchange chromatography
LT2748179T (lt) * 2011-10-14 2022-04-11 Takeda Pharmaceutical Company Limited Baltymų gryninimas anijonų mainų chromatografija
SI2970376T1 (sl) * 2013-03-15 2018-09-28 Baxalta Incorporated Metoda čiščenja za vitamin k odvisne proteine z anionsko izmenjevalno kromatografijo

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3101752A1 (de) * 1981-01-21 1982-08-26 Behringwerke Ag, 3550 Marburg "verfahren zur reinigung der blutgerinnungsfaktoren ii, vii, ix und/oder x und danach hergestellte praeparationen"
ES2045167T5 (es) * 1987-10-23 1996-07-01 Centre Regional De Transfusion Preparacion de concentrado de factor ix humano de elevada pureza y de otras proteinas plasmaticas.
US4981952A (en) * 1988-10-04 1991-01-01 Eli Lilly And Company Method for the purification of vitamin K-dependent proteins
AT395596B (de) * 1991-06-20 1993-01-25 Immuno Ag Verfahren zur herstellung von aktiviertem protein c

Also Published As

Publication number Publication date
FI950888A0 (fi) 1995-02-27
ES2161790T3 (es) 2001-12-16
EP0669342B1 (de) 2001-09-05
US5633350A (en) 1997-05-27
CA2143510A1 (en) 1995-08-29
NO322372B1 (no) 2006-09-25
DE4406515C1 (de) 1995-10-19
CZ290471B6 (cs) 2002-07-17
NO950733D0 (no) 1995-02-27
CA2143510C (en) 1999-12-21
ATE205218T1 (de) 2001-09-15
EP0669342A3 (de) 1997-04-16
HU219828B (hu) 2001-08-28
HUT72844A (en) 1996-05-28
HU9500594D0 (en) 1995-04-28
FI116526B (fi) 2005-12-15
SK22695A3 (en) 1995-09-13
CZ53995A3 (en) 1995-09-13
EP0669342A2 (de) 1995-08-30
JPH07258286A (ja) 1995-10-09
DK0669342T3 (da) 2001-11-12
NO950733L (no) 1995-08-29

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