FI950888A0 - Menetelmä K-vitamiinista riippuvaisten proteiinien eristämiseksi ja puhdistamiseksi - Google Patents

Menetelmä K-vitamiinista riippuvaisten proteiinien eristämiseksi ja puhdistamiseksi

Info

Publication number
FI950888A0
FI950888A0 FI950888A FI950888A FI950888A0 FI 950888 A0 FI950888 A0 FI 950888A0 FI 950888 A FI950888 A FI 950888A FI 950888 A FI950888 A FI 950888A FI 950888 A0 FI950888 A0 FI 950888A0
Authority
FI
Finland
Prior art keywords
isolating
vitamin
dependent proteins
proteins
dependent
Prior art date
Application number
FI950888A
Other languages
English (en)
Swedish (sv)
Other versions
FI116526B (fi
FI950888A (fi
Inventor
Bernhard Fischer
Artur Mitterer
Friedrich Dorner
Original Assignee
Immuno Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno Ag filed Critical Immuno Ag
Publication of FI950888A0 publication Critical patent/FI950888A0/fi
Publication of FI950888A publication Critical patent/FI950888A/fi
Application granted granted Critical
Publication of FI116526B publication Critical patent/FI116526B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/647—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6429—Thrombin (3.4.21.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21005—Thrombin (3.4.21.5)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI950888A 1994-02-28 1995-02-27 Menetelmä K-vitamiinista riippuvaisten proteiinien eristämiseksi ja puhdistamiseksi FI116526B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4406515A DE4406515C1 (de) 1994-02-28 1994-02-28 Verfahren zur Isolierung und Reinigung Vitamin K-abhängiger Proteine
DE4406515 1994-02-28

Publications (3)

Publication Number Publication Date
FI950888A0 true FI950888A0 (fi) 1995-02-27
FI950888A FI950888A (fi) 1995-08-29
FI116526B FI116526B (fi) 2005-12-15

Family

ID=6511421

Family Applications (1)

Application Number Title Priority Date Filing Date
FI950888A FI116526B (fi) 1994-02-28 1995-02-27 Menetelmä K-vitamiinista riippuvaisten proteiinien eristämiseksi ja puhdistamiseksi

Country Status (13)

Country Link
US (1) US5633350A (fi)
EP (1) EP0669342B1 (fi)
JP (1) JPH07258286A (fi)
AT (1) ATE205218T1 (fi)
CA (1) CA2143510C (fi)
CZ (1) CZ290471B6 (fi)
DE (1) DE4406515C1 (fi)
DK (1) DK0669342T3 (fi)
ES (1) ES2161790T3 (fi)
FI (1) FI116526B (fi)
HU (1) HU219828B (fi)
NO (1) NO322372B1 (fi)
SK (1) SK22695A3 (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6180757B1 (en) 1998-04-15 2001-01-30 Novo Nordisk A/S Process for the separation of proteins using a CA++ containing eluant
CN1250567C (zh) * 2000-07-21 2006-04-12 财团法人化学及血清疗法研究所 钙离子结合蛋白的提纯方法
US7897734B2 (en) 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
EP1831242B1 (en) * 2004-12-23 2012-09-26 Novo Nordisk Health Care AG Reduction of the content of protein contaminants in compositions comprising a vitamin k-dependent protein of interest
PT1841863E (pt) * 2005-01-14 2010-10-25 Bayer Healthcare Llc Método para a purificação de factor vii
KR101364003B1 (ko) * 2005-04-28 2014-02-21 노보 노르디스크 헬스 케어 악티엔게젤샤프트 활성화된 제ｖｉｉ 인자 폴리펩타이드를 포함하는 밀폐용기와 이의 제조방법 및, 키트와 키트의 사용방법
US7375084B2 (en) 2006-03-07 2008-05-20 Baxter International Inc. Highly phosphorylated and sulfated recombinant factor IX
EP2125866B1 (en) * 2007-02-28 2013-05-22 Baxter International Inc. Method for the purification of recombinant blood coagulation factor ix enriched in sulfated and/or phosphorylated molecules
WO2011086197A1 (en) * 2010-01-18 2011-07-21 Novo Nordisk Health Care Ag Purification of blood coagulation factors
DK2563805T3 (da) 2010-04-29 2020-05-18 Baxalta GmbH Oprensningsfremgangsmåde til divalente kationbindende proteiner på anionbytningsresin
WO2012104339A1 (en) 2011-02-01 2012-08-09 Novo Nordisk A/S Purification of insulin
ES2700933T3 (es) 2011-10-14 2019-02-20 Baxalta GmbH Purificación de proteínas mediante cromatografía de intercambio aniónico
WO2013053887A1 (en) * 2011-10-14 2013-04-18 Baxter International Inc. Protein purification by anion exchange chromatography
DK2970376T3 (en) * 2013-03-15 2018-07-02 Baxalta Inc PURIFICATION PROCEDURE FOR VITAMIN K-DEPENDENT PROTEINS BY ANION EXCHANGE CHROMATOGRAPHY

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3101752A1 (de) * 1981-01-21 1982-08-26 Behringwerke Ag, 3550 Marburg "verfahren zur reinigung der blutgerinnungsfaktoren ii, vii, ix und/oder x und danach hergestellte praeparationen"
EP0317376B2 (fr) * 1987-10-23 1996-04-03 Centre Regional De Transfusion Sanguine De Lille Préparation de concentré de facteur IX humain de haute pureté et d'autres protéines plasmatiques
US4981952A (en) * 1988-10-04 1991-01-01 Eli Lilly And Company Method for the purification of vitamin K-dependent proteins
AT395596B (de) * 1991-06-20 1993-01-25 Immuno Ag Verfahren zur herstellung von aktiviertem protein c

Also Published As

Publication number Publication date
DE4406515C1 (de) 1995-10-19
CZ53995A3 (en) 1995-09-13
NO950733L (no) 1995-08-29
EP0669342B1 (de) 2001-09-05
HU9500594D0 (en) 1995-04-28
EP0669342A3 (de) 1997-04-16
CA2143510C (en) 1999-12-21
US5633350A (en) 1997-05-27
NO950733D0 (no) 1995-02-27
CA2143510A1 (en) 1995-08-29
CZ290471B6 (cs) 2002-07-17
FI116526B (fi) 2005-12-15
HUT72844A (en) 1996-05-28
FI950888A (fi) 1995-08-29
DK0669342T3 (da) 2001-11-12
HU219828B (hu) 2001-08-28
JPH07258286A (ja) 1995-10-09
NO322372B1 (no) 2006-09-25
ES2161790T3 (es) 2001-12-16
EP0669342A2 (de) 1995-08-30
ATE205218T1 (de) 2001-09-15
SK22695A3 (en) 1995-09-13

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