NO950733D0 - Fremgangsmåte for isolering og rensing av proteiner som er avhengig av vitamin K - Google Patents

Fremgangsmåte for isolering og rensing av proteiner som er avhengig av vitamin K

Info

Publication number
NO950733D0
NO950733D0 NO950733A NO950733A NO950733D0 NO 950733 D0 NO950733 D0 NO 950733D0 NO 950733 A NO950733 A NO 950733A NO 950733 A NO950733 A NO 950733A NO 950733 D0 NO950733 D0 NO 950733D0
Authority
NO
Norway
Prior art keywords
vitamin
isolating
purifying protein
protein dependent
dependent
Prior art date
Application number
NO950733A
Other languages
English (en)
Other versions
NO322372B1 (no
NO950733L (no
Inventor
Bernhard Fischer
Artur Mitterer
Friedrich Dorner
Original Assignee
Immuno Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno Ag filed Critical Immuno Ag
Publication of NO950733D0 publication Critical patent/NO950733D0/no
Publication of NO950733L publication Critical patent/NO950733L/no
Publication of NO322372B1 publication Critical patent/NO322372B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/647—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6429—Thrombin (3.4.21.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21005—Thrombin (3.4.21.5)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO19950733A 1994-02-28 1995-02-27 Fremgangsmate for separasjon av et vitamin K-avhengig protein fra ikke-vitamin K-avhengige, medfolgende proteiner fra en proteinholdig losning NO322372B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4406515A DE4406515C1 (de) 1994-02-28 1994-02-28 Verfahren zur Isolierung und Reinigung Vitamin K-abhängiger Proteine

Publications (3)

Publication Number Publication Date
NO950733D0 true NO950733D0 (no) 1995-02-27
NO950733L NO950733L (no) 1995-08-29
NO322372B1 NO322372B1 (no) 2006-09-25

Family

ID=6511421

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19950733A NO322372B1 (no) 1994-02-28 1995-02-27 Fremgangsmate for separasjon av et vitamin K-avhengig protein fra ikke-vitamin K-avhengige, medfolgende proteiner fra en proteinholdig losning

Country Status (13)

Country Link
US (1) US5633350A (no)
EP (1) EP0669342B1 (no)
JP (1) JPH07258286A (no)
AT (1) ATE205218T1 (no)
CA (1) CA2143510C (no)
CZ (1) CZ290471B6 (no)
DE (1) DE4406515C1 (no)
DK (1) DK0669342T3 (no)
ES (1) ES2161790T3 (no)
FI (1) FI116526B (no)
HU (1) HU219828B (no)
NO (1) NO322372B1 (no)
SK (1) SK22695A3 (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2245824T3 (es) 1998-04-15 2006-01-16 Novo Nordisk A/S Nuevo proceso de separacion de proteinas utilizando un eluyente que contiene ca++.
CN1250567C (zh) * 2000-07-21 2006-04-12 财团法人化学及血清疗法研究所 钙离子结合蛋白的提纯方法
US7897734B2 (en) 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
BRPI0519626A2 (pt) * 2004-12-23 2009-02-25 Novo Nordisk Healthcare Ag mÉtodos para a reduÇço do teor de um ou mais contaminantes, do teor de proteÍna s em uma composiÇço, do teor de um ou mais contaminantes de proteÍna em um sobrenadante de cultura de cÉlula, do teor de proteÍna s em um sobrenadante de cultura de cÉlula, composiÇço compreendendo uma proteÍna dependente de vitamina k de interesse
EP1841863B1 (en) * 2005-01-14 2010-08-04 Bayer HealthCare LLC Method for purification of factor vii
CN101184474B (zh) * 2005-04-28 2013-05-29 诺和诺德医疗保健公司 含有活化的凝血因子ⅶ多肽的密封容器，制备这种容器的方法，和试剂盒以及该试剂盒的使用方法
WO2007101681A1 (en) 2006-03-07 2007-09-13 Baxter International Inc Highly phosphorylated and sulfated recombinant factor ix
DK2125866T3 (da) * 2007-02-28 2013-07-29 Baxter Int Fremgangsmåde til rensning af rekombinant blodkoagulationsfaktor IX, som er beriget med sulfaterede og/eller phosphorylerede molekyler
JP6250931B2 (ja) * 2010-01-18 2017-12-20 ノヴォ・ノルディスク・ヘルス・ケア・アーゲー 血液凝固因子の精製
AU2011247567B2 (en) 2010-04-29 2014-06-19 Takeda Pharmaceutical Company Limited Purification method for divalent cation binding proteins on anion exchange resin
JP6110312B2 (ja) 2011-02-01 2017-04-05 ノヴォ ノルディスク アー／エス インスリンの精製
EP2748179B1 (en) * 2011-10-14 2021-12-29 Takeda Pharmaceutical Company Limited Protein purification by anion exchange chromatography
US9701710B2 (en) 2011-10-14 2017-07-11 Baxalta Incorporated Protein purification by anion exchange chromatography
EP2970376B1 (en) * 2013-03-15 2018-05-23 Baxalta Incorporated Purification method for vitamin k dependent proteins by anion exchange chromatography

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3101752A1 (de) * 1981-01-21 1982-08-26 Behringwerke Ag, 3550 Marburg "verfahren zur reinigung der blutgerinnungsfaktoren ii, vii, ix und/oder x und danach hergestellte praeparationen"
EP0317376B2 (fr) * 1987-10-23 1996-04-03 Centre Regional De Transfusion Sanguine De Lille Préparation de concentré de facteur IX humain de haute pureté et d'autres protéines plasmatiques
US4981952A (en) * 1988-10-04 1991-01-01 Eli Lilly And Company Method for the purification of vitamin K-dependent proteins
AT395596B (de) * 1991-06-20 1993-01-25 Immuno Ag Verfahren zur herstellung von aktiviertem protein c

Also Published As

Publication number Publication date
CA2143510C (en) 1999-12-21
EP0669342B1 (de) 2001-09-05
JPH07258286A (ja) 1995-10-09
CZ290471B6 (cs) 2002-07-17
CA2143510A1 (en) 1995-08-29
HU219828B (hu) 2001-08-28
ATE205218T1 (de) 2001-09-15
DK0669342T3 (da) 2001-11-12
NO322372B1 (no) 2006-09-25
EP0669342A3 (de) 1997-04-16
FI950888A0 (fi) 1995-02-27
DE4406515C1 (de) 1995-10-19
NO950733L (no) 1995-08-29
FI950888A (fi) 1995-08-29
US5633350A (en) 1997-05-27
HUT72844A (en) 1996-05-28
SK22695A3 (en) 1995-09-13
ES2161790T3 (es) 2001-12-16
FI116526B (fi) 2005-12-15
EP0669342A2 (de) 1995-08-30
HU9500594D0 (en) 1995-04-28
CZ53995A3 (en) 1995-09-13

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Legal Events

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