KR870700627A - 세팔로스포린 유도체의 신규 제조방법 - Google Patents
세팔로스포린 유도체의 신규 제조방법Info
- Publication number
- KR870700627A KR870700627A KR860700488A KR860700488A KR870700627A KR 870700627 A KR870700627 A KR 870700627A KR 860700488 A KR860700488 A KR 860700488A KR 860700488 A KR860700488 A KR 860700488A KR 870700627 A KR870700627 A KR 870700627A
- Authority
- KR
- South Korea
- Prior art keywords
- cephalosporin derivatives
- new method
- producing cephalosporin
- producing
- derivatives
- Prior art date
Links
- 229930186147 Cephalosporin Natural products 0.000 title abstract 3
- 229940124587 cephalosporin Drugs 0.000 title abstract 3
- 150000001780 cephalosporins Chemical class 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT371584A AT382875B (de) | 1984-11-23 | 1984-11-23 | Verfahren zur herstellung neuer cephalosporanderivate |
ATA3716/84 | 1984-11-23 | ||
AT0371684A AT381315B (de) | 1984-11-23 | 1984-11-23 | Verfahren zur herstellung von cephalosporinderivaten |
ATA3715/84 | 1984-11-23 | ||
PCT/EP1985/000635 WO1986003204A1 (en) | 1984-11-23 | 1985-11-21 | New process for procuding cephalosporine derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
KR870700627A true KR870700627A (ko) | 1987-12-30 |
KR930007260B1 KR930007260B1 (ko) | 1993-08-04 |
Family
ID=25600362
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019860700488A KR930007260B1 (ko) | 1984-11-23 | 1985-11-21 | 세팔로스포린 유도체의 제조방법 |
Country Status (7)
Country | Link |
---|---|
EP (2) | EP0612750B1 (ko) |
JP (4) | JP2572382B2 (ko) |
KR (1) | KR930007260B1 (ko) |
AT (2) | ATE121746T1 (ko) |
DE (2) | DE3588208D1 (ko) |
HK (1) | HK157996A (ko) |
WO (1) | WO1986003204A1 (ko) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4868294A (en) * | 1986-07-11 | 1989-09-19 | Bristol-Myers Company | Process for preparing cephalosporin intermediates |
AT396108B (de) * | 1991-08-21 | 1993-06-25 | Biochemie Gmbh | Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten |
WO1997039002A1 (en) * | 1996-04-12 | 1997-10-23 | Takeda Chemical Industries, Ltd. | Production of 7-aminocephalosporanic acid derivative |
WO2006008749A1 (en) * | 2004-07-16 | 2006-01-26 | Hetero Drugs Limited | Process for preparing pure cephalosporine intermediates |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5127676A (ja) * | 1974-08-30 | 1976-03-08 | Hitachi Ltd | Shiikensukontorooranopinboodonokoseihoho |
JPS5359689A (en) * | 1976-11-09 | 1978-05-29 | Toshin Chemical Co | Production of 77 aminocedhalosporanic acid derivative |
FR2457295A1 (fr) * | 1979-05-25 | 1980-12-19 | Glaxo Group Ltd | Composes intermediaires pour la preparation de cephalosporines |
US4266049A (en) * | 1980-02-20 | 1981-05-05 | Eli Lilly And Company | Process for 3-iodomethyl cephalosporins |
JPS6052754B2 (ja) * | 1981-01-29 | 1985-11-21 | 山之内製薬株式会社 | 7−アミノ−3−ハロゲノメチル−△↑3−セフェム−4−カルボン酸類およびその製法 |
US4336253A (en) * | 1981-03-11 | 1982-06-22 | Eli Lilly And Company | Cephalosporin antibiotics |
JPS6011917B2 (ja) * | 1981-04-09 | 1985-03-28 | 山之内製薬株式会社 | 新規なセファロスポリン化合物 |
ZA826538B (en) * | 1981-09-08 | 1984-04-25 | Lilly Co Eli | Thieno and furopyridinium-substituted cephalosporin derivatives |
US4396620A (en) * | 1981-09-08 | 1983-08-02 | Eli Lilly And Company | Cephalosporin quinolinium betaines |
US4401668A (en) * | 1981-10-02 | 1983-08-30 | Eli Lilly And Company | Pyrazinium substituted cephalosporins |
DE3316798A1 (de) * | 1983-05-07 | 1984-11-08 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von cephemverbindungen |
DE3316797A1 (de) * | 1983-05-07 | 1984-11-08 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von cephemverbindungen |
JPS60132993A (ja) * | 1983-11-18 | 1985-07-16 | Yamanouchi Pharmaceut Co Ltd | 7−{α−(2−アミノ−4−チアゾリル)−α−〔(2−アミノ−4−チアゾリル)メトキシイミノ〕アセトアミド}−3−(置換−1−ピリジニオメチル)−3−セフェム−4−カルボン酸 |
JPS60136586A (ja) * | 1983-12-26 | 1985-07-20 | Yamanouchi Pharmaceut Co Ltd | 7‐〔α‐(2‐アミノ‐4‐チアゾリル)‐α‐(チオカルバモイルメトキシイミノ)アセトアミド〕‐3‐置換‐Δ↑3‐セフエム‐4‐カルボン酸 |
JPS60188389A (ja) * | 1984-03-07 | 1985-09-25 | Yamanouchi Pharmaceut Co Ltd | 7−〔α−(2−アミノ−4−チアゾリル)−α−(チオカルバモイルメトキシイミノ)アセトアミド〕−3−置換メチル−Δ↑3−セフエム−4−カルボン酸 |
JPS60169486A (ja) * | 1984-02-10 | 1985-09-02 | Yamanouchi Pharmaceut Co Ltd | 7−アミノ−3−置換メチル−3−セフエム−4−カルボン酸およびその低級アルキルシリル誘導体の製造法 |
-
1985
- 1985-11-21 AT AT86900093T patent/ATE121746T1/de not_active IP Right Cessation
- 1985-11-21 EP EP94105662A patent/EP0612750B1/de not_active Expired - Lifetime
- 1985-11-21 WO PCT/EP1985/000635 patent/WO1986003204A1/de active IP Right Grant
- 1985-11-21 JP JP61500166A patent/JP2572382B2/ja not_active Expired - Lifetime
- 1985-11-21 KR KR1019860700488A patent/KR930007260B1/ko not_active IP Right Cessation
- 1985-11-21 AT AT94105662T patent/ATE177104T1/de not_active IP Right Cessation
- 1985-11-21 DE DE3588208T patent/DE3588208D1/de not_active Expired - Lifetime
- 1985-11-21 DE DE3588014T patent/DE3588014D1/de not_active Expired - Lifetime
- 1985-11-21 EP EP86900093A patent/EP0204781B1/de not_active Expired - Lifetime
-
1994
- 1994-11-24 JP JP6289506A patent/JP2625647B2/ja not_active Expired - Lifetime
-
1995
- 1995-07-12 JP JP7175986A patent/JP2881746B2/ja not_active Expired - Lifetime
-
1996
- 1996-08-22 HK HK157996A patent/HK157996A/xx not_active IP Right Cessation
-
1998
- 1998-05-13 JP JP10130236A patent/JP2905775B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2572382B2 (ja) | 1997-01-16 |
ATE177104T1 (de) | 1999-03-15 |
KR930007260B1 (ko) | 1993-08-04 |
JPH0881479A (ja) | 1996-03-26 |
JPH1160583A (ja) | 1999-03-02 |
WO1986003204A1 (en) | 1986-06-05 |
DE3588014D1 (de) | 1995-06-01 |
ATE121746T1 (de) | 1995-05-15 |
EP0612750A3 (en) | 1994-09-28 |
EP0612750B1 (de) | 1999-03-03 |
JP2625647B2 (ja) | 1997-07-02 |
JP2881746B2 (ja) | 1999-04-12 |
EP0204781B1 (de) | 1995-04-26 |
JPS62500873A (ja) | 1987-04-09 |
EP0612750A2 (de) | 1994-08-31 |
JPH07165765A (ja) | 1995-06-27 |
DE3588208D1 (de) | 1999-04-08 |
JP2905775B2 (ja) | 1999-06-14 |
HK157996A (en) | 1996-08-30 |
EP0204781A1 (de) | 1986-12-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
G160 | Decision to publish patent application | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
FPAY | Annual fee payment |
Payment date: 20040714 Year of fee payment: 12 |
|
LAPS | Lapse due to unpaid annual fee |