KR860004897A - 세팔로스포린 유도체의 제조방법 - Google Patents

세팔로스포린 유도체의 제조방법

Info

Publication number
KR860004897A
KR860004897A KR1019850009834A KR850009834A KR860004897A KR 860004897 A KR860004897 A KR 860004897A KR 1019850009834 A KR1019850009834 A KR 1019850009834A KR 850009834 A KR850009834 A KR 850009834A KR 860004897 A KR860004897 A KR 860004897A
Authority
KR
South Korea
Prior art keywords
cephalosporin derivatives
preparing cephalosporin
preparing
derivatives
cephalosporin
Prior art date
Application number
KR1019850009834A
Other languages
English (en)
Other versions
KR930005589B1 (ko
Inventor
스스무 나까가와
료오스께 우시지마
후미오 나까노
고지 야마다
에이이찌 마노
Original Assignee
반유 세이야꾸 가부시끼가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP60171839A external-priority patent/JPH0645629B2/ja
Application filed by 반유 세이야꾸 가부시끼가이샤 filed Critical 반유 세이야꾸 가부시끼가이샤
Publication of KR860004897A publication Critical patent/KR860004897A/ko
Application granted granted Critical
Publication of KR930005589B1 publication Critical patent/KR930005589B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019850009834A 1984-12-27 1985-12-26 세팔로스포린 유도체의 제조방법 KR930005589B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP27359184 1984-12-27
JP273,591 1984-12-27
JP171,839 1985-08-06
JP60171839A JPH0645629B2 (ja) 1985-08-06 1985-08-06 新規セフアロスポリン誘導体

Publications (2)

Publication Number Publication Date
KR860004897A true KR860004897A (ko) 1986-07-14
KR930005589B1 KR930005589B1 (ko) 1993-06-23

Family

ID=26494424

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019850009834A KR930005589B1 (ko) 1984-12-27 1985-12-26 세팔로스포린 유도체의 제조방법

Country Status (7)

Country Link
US (1) US4677100A (ko)
EP (2) EP0452987B1 (ko)
KR (1) KR930005589B1 (ko)
CN (1) CN1013274B (ko)
CA (1) CA1267647A (ko)
DE (2) DE3585434D1 (ko)
ES (2) ES8704943A1 (ko)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4883868A (en) * 1984-12-27 1989-11-28 Banyu Pharmaceutical Co., Ltd. 7-amino-3-(substituted isoindolinium)methyl-3-cephem derivatives
US4959469A (en) * 1984-12-27 1990-09-25 Banyu Pharmaceutical Company, Ltd. Crystalline cephalosporin compounds
DE3688128D1 (de) * 1985-12-09 1993-04-29 Banyu Pharma Co Ltd Isoindolinderivate und verfahren zu ihrer herstellung.
ZA877987B (en) * 1986-11-12 1988-08-31 Ici Pharma Antibiotic compounds
DE3750673T2 (de) * 1986-11-21 1995-03-16 Ici Pharma Cephalosporine, Verfahren zu ihrer Herstellung und pharmazeutische Präparate.
EP0271064A3 (en) * 1986-12-09 1990-02-14 Banyu Pharmaceutical Co., Ltd. 7-amino-3-(substituted isoindolinium)methyl-3-cephem derivatives and process for their production
US4958029A (en) * 1987-01-13 1990-09-18 Banyu Pharmaceutical Co., Ltd. Process for the production of isoindoline derivatives, novel intermediates and process for their production
EP0321562B1 (en) * 1987-06-25 1993-11-24 Banyu Pharmaceutical Co., Ltd. Crystalline cephalosporin compounds, process for their preparation, and intermediates for their preparation
US5232918A (en) * 1987-07-23 1993-08-03 Imperial Chemical Industries Plc Cephalosporin derivatives
DE3854684T2 (de) * 1987-07-23 1996-03-28 Zeneca Pharma Sa Cephalosporinverbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate.
GB8816519D0 (en) * 1987-07-23 1988-08-17 Ici Plc Antibiotic compounds
ATE131824T1 (de) * 1987-07-23 1996-01-15 Zeneca Pharma Sa Cephalosporinverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische präparate
NO903360L (no) * 1989-08-11 1991-02-12 Ici Pharma Antibiotiske forbindelser.
US5126336A (en) * 1990-08-23 1992-06-30 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
EP0544166A3 (en) * 1991-11-26 1993-11-03 Hoffmann La Roche Cephalosporinderivatives
DE618979T1 (de) * 1991-12-19 1995-05-18 Novo Nordisk As Verbesserte methode zur herstellung von bestimmten -g(b)-lactam-antibiotika.
US5834519A (en) 1996-10-11 1998-11-10 Wayne State University Stabilized gas-supersaturated emulsions and suspensions
CN102050830B (zh) * 2009-10-30 2012-12-26 山东轩竹医药科技有限公司 一种含有氮稠杂环的头孢菌素衍生物
CN102050831B (zh) * 2009-10-30 2014-02-26 山东轩竹医药科技有限公司 一种头孢菌素衍生物
CN107586305A (zh) * 2017-06-23 2018-01-16 浙江惠迪森药业有限公司 一种β‑内酰胺类化合物羧基及羟基保护基脱除方法
CN113480491B (zh) * 2021-09-08 2022-05-06 山东昌邑四方医药化工有限公司 一种从头孢托仑母核生产废液中回收4-甲基噻唑-5-甲醛和三苯基氧膦的方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
US4160830A (en) * 1971-07-17 1979-07-10 Takeda Chemical Industries, Ltd. Cephalosporins
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
JPS6011713B2 (ja) * 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
GB1591439A (en) * 1976-10-01 1981-06-24 Glaxo Operations Ltd 7-syn (oxyimino -acylamido) cephalosporins
JPS609719B2 (ja) * 1977-08-06 1985-03-12 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
FR2410655A1 (fr) * 1977-12-05 1979-06-29 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-substitue 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4416879A (en) * 1980-09-08 1983-11-22 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4396619A (en) * 1981-09-08 1983-08-02 Eli Lilly And Company Cephalosporin betaines
US4382931A (en) * 1981-09-08 1983-05-10 Eli Lilly And Company 3'-Substituted quinolinium cephalosporins
US4382932A (en) * 1981-09-08 1983-05-10 Eli Lilly And Company Isoquinolinium substituted cephalosporins
US4396620A (en) * 1981-09-08 1983-08-02 Eli Lilly And Company Cephalosporin quinolinium betaines
US4379787A (en) * 1981-10-02 1983-04-12 Eli Lilly And Company Oximino-substituted cephalosporin compounds
GB2111663B (en) * 1981-12-16 1986-03-26 Ocean Phoenix Holdings Nv Tank for the storage and transport of pressurised fluid
US4406899A (en) * 1982-03-04 1983-09-27 Bristol-Myers Company Cephalosporins
DE3247614A1 (de) * 1982-12-23 1984-07-05 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
EP0137442A3 (de) * 1983-10-08 1986-01-15 Hoechst Aktiengesellschaft Cephalosporinderivate und Verfahren zu ihrer Herstellung
DE3409431A1 (de) * 1983-10-08 1985-04-18 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3688128D1 (de) * 1985-12-09 1993-04-29 Banyu Pharma Co Ltd Isoindolinderivate und verfahren zu ihrer herstellung.

Also Published As

Publication number Publication date
ES557051A0 (es) 1987-12-16
EP0186187A3 (en) 1987-04-15
ES8801288A1 (es) 1987-12-16
CA1267647A (en) 1990-04-10
ES8704943A1 (es) 1987-04-16
KR930005589B1 (ko) 1993-06-23
EP0452987A1 (en) 1991-10-23
ES550369A0 (es) 1987-04-16
CN1013274B (zh) 1991-07-24
EP0186187A2 (en) 1986-07-02
CN85109769A (zh) 1986-12-17
DE3585434D1 (de) 1992-04-02
US4677100A (en) 1987-06-30
EP0452987B1 (en) 1995-03-01
DE3587997D1 (de) 1995-04-06
EP0186187B1 (en) 1992-02-26

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