KR860004919A - 뉴클레오시드 유도체의 제조방법 - Google Patents

뉴클레오시드 유도체의 제조방법

Info

Publication number
KR860004919A
KR860004919A KR1019840007754A KR840007754A KR860004919A KR 860004919 A KR860004919 A KR 860004919A KR 1019840007754 A KR1019840007754 A KR 1019840007754A KR 840007754 A KR840007754 A KR 840007754A KR 860004919 A KR860004919 A KR 860004919A
Authority
KR
South Korea
Prior art keywords
nucleoside derivatives
preparing nucleoside
preparing
derivatives
nucleoside
Prior art date
Application number
KR1019840007754A
Other languages
English (en)
Other versions
KR880000094B1 (ko
Inventor
홍청일
이기홍
김지한
Original Assignee
보령제약 주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 보령제약 주식회사 filed Critical 보령제약 주식회사
Priority to KR1019840007754A priority Critical patent/KR880000094B1/ko
Priority to KR1019850006039A priority patent/KR880000093B1/ko
Priority to ES549558A priority patent/ES8701192A1/es
Priority to ES549587A priority patent/ES8706163A1/es
Priority to FR8518129A priority patent/FR2574412B1/fr
Priority to GB08530115A priority patent/GB2168350B/en
Priority to GB08530114A priority patent/GB2168353B/en
Priority to FR8518130A priority patent/FR2574411B1/fr
Priority to JP60275853A priority patent/JPS61263996A/ja
Priority to JP60275852A priority patent/JPS61197591A/ja
Priority to DE3543346A priority patent/DE3543346C2/de
Priority to DE19853543347 priority patent/DE3543347A1/de
Publication of KR860004919A publication Critical patent/KR860004919A/ko
Priority to ES557428A priority patent/ES8802363A1/es
Application granted granted Critical
Publication of KR880000094B1 publication Critical patent/KR880000094B1/ko

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • C07H19/10Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/12Triazine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/14Pyrrolo-pyrimidine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • C07H19/20Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1019840007754A 1984-12-07 1984-12-07 뉴클레오시드 유도체의 제조방법 KR880000094B1 (ko)

Priority Applications (13)

Application Number Priority Date Filing Date Title
KR1019840007754A KR880000094B1 (ko) 1984-12-07 1984-12-07 뉴클레오시드 유도체의 제조방법
KR1019850006039A KR880000093B1 (ko) 1984-12-07 1985-08-22 뉴클레오시드 유도체의 제조방법
ES549558A ES8701192A1 (es) 1984-12-07 1985-12-04 Procedimiento para la preparacion de nucleosidos
ES549587A ES8706163A1 (es) 1984-12-07 1985-12-05 Procedimiento para la fabricacion de nuevos derivados nu- cleosidos
GB08530115A GB2168350B (en) 1984-12-07 1985-12-06 Nucleoside derivatives
GB08530114A GB2168353B (en) 1984-12-07 1985-12-06 Process for preparing nucleoside derivatives
FR8518129A FR2574412B1 (fr) 1984-12-07 1985-12-06 Procede de fabrication de derives de nucleosides utiles notamment comme agents anticancereux
FR8518130A FR2574411B1 (fr) 1984-12-07 1985-12-06 Nouveaux derives de nucleosides, utiles notamment comme medicaments anticancereux, et leur procede de fabrication
JP60275853A JPS61263996A (ja) 1984-12-07 1985-12-07 新規ヌクレオシド誘導体およびその製造法
JP60275852A JPS61197591A (ja) 1984-12-07 1985-12-07 ヌクレオシド誘導体の製造方法
DE3543346A DE3543346C2 (de) 1984-12-07 1985-12-07 Verfahren zur Herstellung von Nucleosidkonjugaten
DE19853543347 DE3543347A1 (de) 1984-12-07 1985-12-07 Verfahren zur herstellung von nucleosidderivaten
ES557428A ES8802363A1 (es) 1984-12-07 1987-02-27 Procedimiento para la fabricacion de derivados nucleosidos

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019840007754A KR880000094B1 (ko) 1984-12-07 1984-12-07 뉴클레오시드 유도체의 제조방법

Publications (2)

Publication Number Publication Date
KR860004919A true KR860004919A (ko) 1986-07-16
KR880000094B1 KR880000094B1 (ko) 1988-02-23

Family

ID=19236525

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840007754A KR880000094B1 (ko) 1984-12-07 1984-12-07 뉴클레오시드 유도체의 제조방법

Country Status (6)

Country Link
JP (2) JPS61263996A (ko)
KR (1) KR880000094B1 (ko)
DE (1) DE3543347A1 (ko)
ES (1) ES8701192A1 (ko)
FR (1) FR2574412B1 (ko)
GB (1) GB2168353B (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6599887B2 (en) 1988-07-07 2003-07-29 Chimerix, Inc. Methods of treating viral infections using antiviral liponucleotides
MY164523A (en) 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
EP1294735A2 (en) 2000-05-26 2003-03-26 Novirio Pharmaceuticals Limited Methods and compositions for treating flaviviruses and pestiviruses
US7824851B2 (en) 2002-11-15 2010-11-02 Idenix Pharmaceuticals, Inc. 2′-branched nucleosides and Flaviviridae mutation
ITFI20040173A1 (it) 2004-08-03 2004-11-03 Protera S R L Profarmaci attivati da dna polimerasi dipendenti da rna
GB0505781D0 (en) * 2005-03-21 2005-04-27 Univ Cardiff Chemical compounds
TWI464402B (zh) * 2011-01-12 2014-12-11 Univ Kaohsiung Medical 將核酸接上小分子的方法
EP2712868A1 (en) * 2012-09-28 2014-04-02 B. Braun Melsungen AG 5-Fluoruoracil Derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4283394A (en) * 1979-08-06 1981-08-11 Research Corporation Cytotoxic nucleoside-corticosteroid phosphodiesters

Also Published As

Publication number Publication date
JPS6338360B2 (ko) 1988-07-29
JPS61263996A (ja) 1986-11-21
KR880000094B1 (ko) 1988-02-23
ES549558A0 (es) 1986-12-01
FR2574412A1 (fr) 1986-06-13
JPH0129800B2 (ko) 1989-06-14
GB2168353B (en) 1988-06-22
GB2168353A (en) 1986-06-18
ES8701192A1 (es) 1986-12-01
DE3543347A1 (de) 1986-06-12
FR2574412B1 (fr) 1989-06-09
DE3543347C2 (ko) 1989-11-09
JPS61197591A (ja) 1986-09-01
GB8530114D0 (en) 1986-01-15

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