KR860003260A - 옥스인돌 카복스 아미드 유도체의 제조방법 - Google Patents
옥스인돌 카복스 아미드 유도체의 제조방법Info
- Publication number
- KR860003260A KR860003260A KR1019850008037A KR850008037A KR860003260A KR 860003260 A KR860003260 A KR 860003260A KR 1019850008037 A KR1019850008037 A KR 1019850008037A KR 850008037 A KR850008037 A KR 850008037A KR 860003260 A KR860003260 A KR 860003260A
- Authority
- KR
- South Korea
- Prior art keywords
- carboxamide derivatives
- preparing
- oxindole carboxamide
- preparing oxindole
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/666,953 US4644005A (en) | 1984-10-31 | 1984-10-31 | Oxindole antiinflammatory agents |
| US666,953 | 1984-10-31 | ||
| US06/762,998 US4686224A (en) | 1984-10-31 | 1985-08-06 | Oxindole antiinflammatory agents |
| US762,998 | 1991-09-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR860003260A true KR860003260A (ko) | 1986-05-21 |
| KR870001269B1 KR870001269B1 (ko) | 1987-06-30 |
Family
ID=27099577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019850008037A KR870001269B1 (ko) | 1984-10-31 | 1985-10-30 | 옥스인돌 카복스 아미드 유도체의 제조방법 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4686224A (ko) |
| EP (1) | EP0181136B1 (ko) |
| KR (1) | KR870001269B1 (ko) |
| AU (1) | AU555051B2 (ko) |
| CA (1) | CA1247099A (ko) |
| DE (1) | DE3585719D1 (ko) |
| DK (1) | DK163990C (ko) |
| ES (1) | ES8707731A1 (ko) |
| FI (1) | FI81340C (ko) |
| GR (1) | GR852629B (ko) |
| HU (1) | HU194168B (ko) |
| IE (1) | IE58207B1 (ko) |
| IL (1) | IL76854A (ko) |
| PH (3) | PH20985A (ko) |
| PL (2) | PL150842B1 (ko) |
| PT (1) | PT81393B (ko) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5128352A (en) * | 1989-01-10 | 1992-07-07 | Pfizer Inc. | Anti-inflammatory 1-heteroaryl-oxindole-3-carboxamides |
| WO1990008145A1 (en) * | 1989-01-10 | 1990-07-26 | Pfizer Inc. | Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles |
| JPH0717589B2 (ja) * | 1990-01-22 | 1995-03-01 | ファイザー製薬株式会社 | 新規１，３―ジカルボニル化合物およびその組成物 |
| CH687764A5 (de) * | 1992-07-02 | 1997-02-14 | Lonza Ag Gampel Wallis Geschof | Verfahren zur Herstellung von 7-Acylindolen. |
| US5449788A (en) * | 1994-01-28 | 1995-09-12 | Catalytica, Inc. | Process for preparing 2-oxindole-1-carboxamides |
| GB9414139D0 (en) * | 1994-07-13 | 1994-08-31 | Smithkline Beecham Plc | Novel compounds |
| CN102050758A (zh) * | 2000-09-14 | 2011-05-11 | 田边三菱制药株式会社 | 酰胺衍生物及其制备药物的用途 |
| US7186745B2 (en) | 2001-03-06 | 2007-03-06 | Astrazeneca Ab | Indolone derivatives having vascular damaging activity |
| ATE445838T1 (de) | 2001-07-25 | 2009-10-15 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
| WO2005041957A1 (en) * | 2003-10-29 | 2005-05-12 | Pfizer Products Inc. | Oxindole derivatives and their use as phosphodiesterase type 2 inhibitors |
| EP2671508B1 (en) | 2005-04-28 | 2020-09-16 | Proteus Digital Health, Inc. | Pharma-informatics system |
| CA2663377A1 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
| HUE059078T2 (hu) | 2009-02-20 | 2022-10-28 | Enhanx Biopharm Inc | Glutation-alapú hatóanyagszállító rendszer |
| JP2012526144A (ja) | 2009-05-06 | 2012-10-25 | ラボラトリー スキン ケア インコーポレイテッド | 活性物質−リン酸カルシウム粒子複合体を含む経皮送達組成物およびその使用方法 |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| CN104130176A (zh) * | 2014-06-13 | 2014-11-05 | 天津科技大学 | 一种1,5-二取代吲哚酮类衍生物及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE756447A (fr) * | 1969-10-15 | 1971-03-22 | Pfizer | Oxindolecarboxamides |
| US3749731A (en) * | 1971-07-08 | 1973-07-31 | Warner Lambert Co | 2-oxo-n-(2-thiazolyl)-3-indoline-carboxamide |
| DE3114351A1 (de) * | 1981-04-09 | 1982-11-04 | Hoechst Ag, 6000 Frankfurt | "oxindol-derivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel mit neuroanaboler wirkung" |
| AU8509882A (en) * | 1981-06-30 | 1983-01-06 | Merck & Co., Inc. | Tricyclic derivatives of substituted pyrrole acids |
| DE3582890D1 (de) * | 1984-02-07 | 1991-06-20 | Pfizer | 2-oxindolzwischenprodukte. |
| PT80116B (pt) * | 1984-03-19 | 1987-10-20 | Pfizer | Processo para a producao de 2-oxindole-1-carboxamidas e de intermediarios para esse efeito |
| US4556672A (en) * | 1984-03-19 | 1985-12-03 | Pfizer Inc. | 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents |
-
1985
- 1985-08-06 US US06/762,998 patent/US4686224A/en not_active Expired - Lifetime
- 1985-10-28 IL IL76854A patent/IL76854A/xx not_active IP Right Cessation
- 1985-10-29 PL PL1985262327A patent/PL150842B1/pl unknown
- 1985-10-29 PL PL1985255990A patent/PL145239B1/pl unknown
- 1985-10-29 PT PT81393A patent/PT81393B/pt not_active IP Right Cessation
- 1985-10-29 DE DE8585307794T patent/DE3585719D1/de not_active Expired - Fee Related
- 1985-10-29 EP EP85307794A patent/EP0181136B1/en not_active Expired - Lifetime
- 1985-10-30 FI FI854258A patent/FI81340C/fi not_active IP Right Cessation
- 1985-10-30 DK DK497685A patent/DK163990C/da active
- 1985-10-30 HU HU854158A patent/HU194168B/hu not_active IP Right Cessation
- 1985-10-30 AU AU49189/85A patent/AU555051B2/en not_active Ceased
- 1985-10-30 KR KR1019850008037A patent/KR870001269B1/ko not_active IP Right Cessation
- 1985-10-30 CA CA000494220A patent/CA1247099A/en not_active Expired
- 1985-10-31 GR GR852629A patent/GR852629B/el unknown
- 1985-10-31 PH PH33000A patent/PH20985A/en unknown
- 1985-11-01 IE IE270385A patent/IE58207B1/en not_active IP Right Cessation
-
1986
- 1986-04-30 ES ES554609A patent/ES8707731A1/es not_active Expired
- 1986-12-05 PH PH34563A patent/PH24091A/en unknown
- 1986-12-05 PH PH34562A patent/PH23130A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL262327A1 (en) | 1987-11-02 |
| PT81393B (pt) | 1988-02-17 |
| HU194168B (en) | 1988-01-28 |
| IL76854A (en) | 1989-05-15 |
| PL150842B1 (en) | 1990-07-31 |
| PH24091A (en) | 1990-03-05 |
| AU4918985A (en) | 1986-05-08 |
| CA1247099A (en) | 1988-12-20 |
| GR852629B (ko) | 1986-03-04 |
| EP0181136B1 (en) | 1992-03-25 |
| FI854258L (fi) | 1986-05-01 |
| KR870001269B1 (ko) | 1987-06-30 |
| AU555051B2 (en) | 1986-09-11 |
| FI81340C (fi) | 1990-10-10 |
| PL255990A1 (en) | 1987-03-23 |
| US4686224A (en) | 1987-08-11 |
| EP0181136A2 (en) | 1986-05-14 |
| PT81393A (en) | 1985-11-01 |
| DK163990B (da) | 1992-04-27 |
| HUT39428A (en) | 1986-09-29 |
| FI81340B (fi) | 1990-06-29 |
| IE58207B1 (en) | 1993-07-28 |
| IL76854A0 (en) | 1986-02-28 |
| DK497685A (da) | 1986-05-01 |
| DE3585719D1 (de) | 1992-04-30 |
| DK163990C (da) | 1992-09-21 |
| IE852703L (en) | 1986-04-30 |
| ES554609A0 (es) | 1987-08-16 |
| PL145239B1 (en) | 1988-08-31 |
| EP0181136A3 (en) | 1987-10-28 |
| FI854258A0 (fi) | 1985-10-30 |
| ES8707731A1 (es) | 1987-08-16 |
| PH20985A (en) | 1987-06-18 |
| DK497685D0 (da) | 1985-10-30 |
| PH23130A (en) | 1989-05-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO850300L (no) | Fremgangsmaate for fremstilling av 3-imidazolylmetyl-tetrahydrokarbazolon-derivater | |
| KR880013431A (ko) | 4-[-메틸 및 -헤테로]피페리딘 유도체의 제조방법 | |
| DK351185A (da) | Indolderivater | |
| KR860005811A (ko) | 티아졸리딘디온 유도체의 제조방법 | |
| FI882007A0 (fi) | Menetelmä steroidi-5- -reduktaasin inhibiittorien valmistamiseksi | |
| KR860004897A (ko) | 세팔로스포린 유도체의 제조방법 | |
| KR860003260A (ko) | 옥스인돌 카복스 아미드 유도체의 제조방법 | |
| KR860005574A (ko) | 뉴클레오시드 유도체의 제조방법 | |
| DK167984A (da) | Alkaloidderivater | |
| ES547466A0 (es) | Procedimiento de preparacion de derivados aminometilfosfoni-cos | |
| KR860004922A (ko) | N-포르밀-α-아스파르틸페닐알라닌의 제조방법 | |
| KR870001175A (ko) | 5-치환된-6-아미노피리미딘 유도체의 제조방법 | |
| ES538852A0 (es) | Procedimiento de obtencion de derivados de poliamina | |
| KR860004919A (ko) | 뉴클레오시드 유도체의 제조방법 | |
| ES551481A0 (es) | Procedimiento de preparar derivados iminotiazolidinicos | |
| NO851550L (no) | Fremgangsmaate for fremstilling av imidazolderivater | |
| DE3465987D1 (de) | Process for preparing azetidinone derivatives | |
| KR860004851A (ko) | 피롤리딘 유도체의 제조방법 | |
| IT8505129A1 (it) | Procedimento per preparare 3-esometilenecefam derivati | |
| DE3464910D1 (de) | Process for preparing pyrimidinetrione derivatives | |
| KR860004939A (ko) | N-치환된 아실-락탐 화합물을 제조하는 방법 | |
| NO841485L (no) | Fremgangsmaate for fremstilling av substituerte difenylazometinderivater | |
| NO844466L (no) | Fremgangsmaate for fremstilling av pyrimidoisokinolin-derivater | |
| DE3463140D1 (de) | Process for preparing azetidinone derivatives | |
| KR850003384A (ko) | 9-카바모일플루오렌 유도체의 제조방법 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| E902 | Notification of reason for refusal | ||
| G160 | Decision to publish patent application | ||
| E701 | Decision to grant or registration of patent right | ||
| GRNT | Written decision to grant | ||
| FPAY | Annual fee payment |
Payment date: 19990402 Year of fee payment: 13 |
|
| LAPS | Lapse due to unpaid annual fee |