FI854258L - Anti-inflammatoriska oxindolfoereningar. - Google Patents
Anti-inflammatoriska oxindolfoereningar.Info
- Publication number
- FI854258L FI854258L FI854258A FI854258A FI854258L FI 854258 L FI854258 L FI 854258L FI 854258 A FI854258 A FI 854258A FI 854258 A FI854258 A FI 854258A FI 854258 L FI854258 L FI 854258L
- Authority
- FI
- Finland
- Prior art keywords
- oxindolfoereningar
- inflammatory
- inflammatory oxindolfoereningar
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/666,953 US4644005A (en) | 1984-10-31 | 1984-10-31 | Oxindole antiinflammatory agents |
| US66695384 | 1984-10-31 | ||
| US06/762,998 US4686224A (en) | 1984-10-31 | 1985-08-06 | Oxindole antiinflammatory agents |
| US76299885 | 1985-08-06 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI854258A0 FI854258A0 (fi) | 1985-10-30 |
| FI854258L true FI854258L (fi) | 1986-05-01 |
| FI81340B FI81340B (fi) | 1990-06-29 |
| FI81340C FI81340C (fi) | 1990-10-10 |
Family
ID=27099577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI854258A FI81340C (fi) | 1984-10-31 | 1985-10-30 | Foerfarande foer framstaellning av nya, terapeutiskt anvaendbara oxindolkarboxamidderivat. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4686224A (fi) |
| EP (1) | EP0181136B1 (fi) |
| KR (1) | KR870001269B1 (fi) |
| AU (1) | AU555051B2 (fi) |
| CA (1) | CA1247099A (fi) |
| DE (1) | DE3585719D1 (fi) |
| DK (1) | DK163990C (fi) |
| ES (1) | ES8707731A1 (fi) |
| FI (1) | FI81340C (fi) |
| GR (1) | GR852629B (fi) |
| HU (1) | HU194168B (fi) |
| IE (1) | IE58207B1 (fi) |
| IL (1) | IL76854A (fi) |
| PH (3) | PH20985A (fi) |
| PL (2) | PL145239B1 (fi) |
| PT (1) | PT81393B (fi) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990008146A1 (en) * | 1989-01-10 | 1990-07-26 | Pfizer Inc. | Anti-inflammatory 1-heteroaryl-oxindole-3-carboxamides |
| WO1990008145A1 (en) * | 1989-01-10 | 1990-07-26 | Pfizer Inc. | Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles |
| JPH0717589B2 (ja) * | 1990-01-22 | 1995-03-01 | ファイザー製薬株式会社 | 新規１，３―ジカルボニル化合物およびその組成物 |
| CH687764A5 (de) * | 1992-07-02 | 1997-02-14 | Lonza Ag Gampel Wallis Geschof | Verfahren zur Herstellung von 7-Acylindolen. |
| US5449788A (en) * | 1994-01-28 | 1995-09-12 | Catalytica, Inc. | Process for preparing 2-oxindole-1-carboxamides |
| GB9414139D0 (en) * | 1994-07-13 | 1994-08-31 | Smithkline Beecham Plc | Novel compounds |
| DK1318140T3 (da) | 2000-09-14 | 2011-07-18 | Mitsubishi Tanabe Pharma Corp | Nye amidderivater og medicinsk anvendelse deraf |
| JP2004529110A (ja) | 2001-03-06 | 2004-09-24 | アストラゼネカ アクチボラグ | 脈管損傷活性を有するインドール誘導体 |
| EP2147679B1 (en) | 2001-07-25 | 2014-06-25 | Raptor Pharmaceutical, Inc. | Compositions for blood-brain barrier transport |
| WO2005041957A1 (en) * | 2003-10-29 | 2005-05-12 | Pfizer Products Inc. | Oxindole derivatives and their use as phosphodiesterase type 2 inhibitors |
| WO2006116718A2 (en) | 2005-04-28 | 2006-11-02 | Proteus Biomedical, Inc. | Pharma-informatics system |
| US8795627B2 (en) | 2007-03-21 | 2014-08-05 | Raptor Pharmaceuticals Inc. | Treatment of liver disorders by administration of RAP conjugates |
| JP5564517B2 (ja) | 2009-02-20 | 2014-07-30 | ティーオー − ビービービー ホールディング ベスローテン フェンノートシャップ | グルタチオンをベースとする薬物送達システム |
| CN102458374A (zh) | 2009-05-06 | 2012-05-16 | 实验室护肤股份有限公司 | 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其使用方法 |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| CN104130176A (zh) * | 2014-06-13 | 2014-11-05 | 天津科技大学 | 一种1,5-二取代吲哚酮类衍生物及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE756447A (fr) * | 1969-10-15 | 1971-03-22 | Pfizer | Oxindolecarboxamides |
| US3749731A (en) * | 1971-07-08 | 1973-07-31 | Warner Lambert Co | 2-oxo-n-(2-thiazolyl)-3-indoline-carboxamide |
| DE3114351A1 (de) * | 1981-04-09 | 1982-11-04 | Hoechst Ag, 6000 Frankfurt | "oxindol-derivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel mit neuroanaboler wirkung" |
| AU8509882A (en) * | 1981-06-30 | 1983-01-06 | Merck & Co., Inc. | Tricyclic derivatives of substituted pyrrole acids |
| DE3582890D1 (de) * | 1984-02-07 | 1991-06-20 | Pfizer | 2-oxindolzwischenprodukte. |
| CA1250832A (en) * | 1984-03-19 | 1989-03-07 | Pfizer | PREPARATION OF 2-OXINDOLE-1-CARBOXAMIDES; INTERMEDIATE PRODUCTS |
| US4556672A (en) * | 1984-03-19 | 1985-12-03 | Pfizer Inc. | 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents |
-
1985
- 1985-08-06 US US06/762,998 patent/US4686224A/en not_active Expired - Lifetime
- 1985-10-28 IL IL76854A patent/IL76854A/xx not_active IP Right Cessation
- 1985-10-29 DE DE8585307794T patent/DE3585719D1/de not_active Expired - Fee Related
- 1985-10-29 PL PL1985255990A patent/PL145239B1/pl unknown
- 1985-10-29 EP EP85307794A patent/EP0181136B1/en not_active Expired - Lifetime
- 1985-10-29 PT PT81393A patent/PT81393B/pt not_active IP Right Cessation
- 1985-10-29 PL PL1985262327A patent/PL150842B1/pl unknown
- 1985-10-30 KR KR1019850008037A patent/KR870001269B1/ko not_active IP Right Cessation
- 1985-10-30 CA CA000494220A patent/CA1247099A/en not_active Expired
- 1985-10-30 DK DK497685A patent/DK163990C/da active
- 1985-10-30 FI FI854258A patent/FI81340C/fi not_active IP Right Cessation
- 1985-10-30 AU AU49189/85A patent/AU555051B2/en not_active Ceased
- 1985-10-30 HU HU854158A patent/HU194168B/hu not_active IP Right Cessation
- 1985-10-31 GR GR852629A patent/GR852629B/el unknown
- 1985-10-31 PH PH33000A patent/PH20985A/en unknown
- 1985-11-01 IE IE270385A patent/IE58207B1/en not_active IP Right Cessation
-
1986
- 1986-04-30 ES ES554609A patent/ES8707731A1/es not_active Expired
- 1986-12-05 PH PH34563A patent/PH24091A/en unknown
- 1986-12-05 PH PH34562A patent/PH23130A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA1247099A (en) | 1988-12-20 |
| IL76854A0 (en) | 1986-02-28 |
| PH23130A (en) | 1989-05-05 |
| PL150842B1 (en) | 1990-07-31 |
| PH24091A (en) | 1990-03-05 |
| DK497685A (da) | 1986-05-01 |
| EP0181136A2 (en) | 1986-05-14 |
| GR852629B (fi) | 1986-03-04 |
| IL76854A (en) | 1989-05-15 |
| US4686224A (en) | 1987-08-11 |
| AU4918985A (en) | 1986-05-08 |
| PT81393B (pt) | 1988-02-17 |
| ES554609A0 (es) | 1987-08-16 |
| AU555051B2 (en) | 1986-09-11 |
| FI81340B (fi) | 1990-06-29 |
| ES8707731A1 (es) | 1987-08-16 |
| FI854258A0 (fi) | 1985-10-30 |
| DE3585719D1 (de) | 1992-04-30 |
| EP0181136A3 (en) | 1987-10-28 |
| PT81393A (en) | 1985-11-01 |
| DK497685D0 (da) | 1985-10-30 |
| HU194168B (en) | 1988-01-28 |
| HUT39428A (en) | 1986-09-29 |
| PL255990A1 (en) | 1987-03-23 |
| IE58207B1 (en) | 1993-07-28 |
| DK163990B (da) | 1992-04-27 |
| KR870001269B1 (ko) | 1987-06-30 |
| PL262327A1 (en) | 1987-11-02 |
| PH20985A (en) | 1987-06-18 |
| IE852703L (en) | 1986-04-30 |
| FI81340C (fi) | 1990-10-10 |
| DK163990C (da) | 1992-09-21 |
| PL145239B1 (en) | 1988-08-31 |
| EP0181136B1 (en) | 1992-03-25 |
| KR860003260A (ko) | 1986-05-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: PFIZER INC. |