FI950044A - Menetelmä proteiini C:n hajoamisen estämiseksi - Google Patents

Menetelmä proteiini C:n hajoamisen estämiseksi Download PDF

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Publication number
FI950044A
FI950044A FI950044A FI950044A FI950044A FI 950044 A FI950044 A FI 950044A FI 950044 A FI950044 A FI 950044A FI 950044 A FI950044 A FI 950044A FI 950044 A FI950044 A FI 950044A
Authority
FI
Finland
Prior art keywords
apc
methods
protein
breakdown
preventing
Prior art date
Application number
FI950044A
Other languages
English (en)
Swedish (sv)
Other versions
FI115635B (fi
FI950044A0 (fi
Inventor
Jr Walter Francis Prouty
Josephine Secnik
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22650141&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI950044(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI950044A0 publication Critical patent/FI950044A0/fi
Publication of FI950044A publication Critical patent/FI950044A/fi
Application granted granted Critical
Publication of FI115635B publication Critical patent/FI115635B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4866—Protein C (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6464—Protein C (3.4.21.69)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
FI950044A 1994-01-05 1995-01-04 Menetelmiä proteiini C:n hajoamisen estämiseksi FI115635B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17783294A 1994-01-05 1994-01-05
US17783294 1994-01-05

Publications (3)

Publication Number Publication Date
FI950044A0 FI950044A0 (fi) 1995-01-04
FI950044A true FI950044A (fi) 1995-07-06
FI115635B FI115635B (fi) 2005-06-15

Family

ID=22650141

Family Applications (1)

Application Number Title Priority Date Filing Date
FI950044A FI115635B (fi) 1994-01-05 1995-01-04 Menetelmiä proteiini C:n hajoamisen estämiseksi

Country Status (29)

Country Link
EP (2) EP1087011A3 (fi)
JP (1) JP3778588B2 (fi)
KR (1) KR950032287A (fi)
CN (1) CN1109891A (fi)
AT (1) ATE201045T1 (fi)
AU (1) AU1003195A (fi)
BR (1) BR9500017A (fi)
CA (1) CA2139468C (fi)
CO (1) CO4600680A1 (fi)
CZ (1) CZ1395A3 (fi)
DE (2) DE10299053I2 (fi)
DK (1) DK0662513T3 (fi)
ES (1) ES2156190T3 (fi)
FI (1) FI115635B (fi)
GR (1) GR3036277T3 (fi)
HU (1) HUT70465A (fi)
IL (1) IL112236A (fi)
LU (2) LU90993I2 (fi)
NL (1) NL300108I2 (fi)
NO (2) NO320157B1 (fi)
NZ (1) NZ270271A (fi)
PE (1) PE43995A1 (fi)
PL (1) PL180703B1 (fi)
PT (1) PT662513E (fi)
RU (1) RU2167936C2 (fi)
SI (1) SI0662513T1 (fi)
UA (1) UA39178C2 (fi)
YU (1) YU295A (fi)
ZA (1) ZA9514B (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6630137B1 (en) 1997-04-28 2003-10-07 Eli Lilly And Company Activated protein C formulations
HU224826B1 (en) * 1997-04-28 2006-02-28 Lilly Co Eli Activated protein c formulations
EP1557463A1 (en) * 1997-04-28 2005-07-27 Eli Lilly & Company Improved methods for processing activated protein C
US7204981B2 (en) 2000-03-28 2007-04-17 Eli Lilly And Company Methods of treating diseases with activated protein C
US7087578B2 (en) 2000-05-24 2006-08-08 Eli Lilly And Company Formulations and methods for treating hypercoagulable states

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT402262B (de) * 1991-06-20 1997-03-25 Immuno Ag Arzneimittel enthaltend aktiviertes protein c

Also Published As

Publication number Publication date
EP0662513B1 (en) 2001-05-09
CA2139468C (en) 2007-08-21
UA39178C2 (uk) 2001-06-15
DE69520844T2 (de) 2001-11-08
PL306671A1 (en) 1995-07-10
NO950018L (no) 1995-07-06
NL300108I2 (nl) 2003-06-02
CN1109891A (zh) 1995-10-11
IL112236A (en) 1999-12-31
EP1087011A2 (en) 2001-03-28
IL112236A0 (en) 1995-03-30
EP0662513A1 (en) 1995-07-12
GR3036277T3 (en) 2001-10-31
FI115635B (fi) 2005-06-15
HU9500021D0 (en) 1995-03-28
SI0662513T1 (en) 2001-10-31
BR9500017A (pt) 1995-10-03
DE69520844D1 (de) 2001-06-13
NO2006006I1 (no) 2006-05-15
KR950032287A (ko) 1995-12-20
CA2139468A1 (en) 1995-07-06
NZ270271A (en) 1996-07-26
CZ1395A3 (en) 1995-07-12
AU1003195A (en) 1995-07-13
NO950018D0 (no) 1995-01-03
PT662513E (pt) 2001-08-30
LU90993I2 (fr) 2003-02-18
ATE201045T1 (de) 2001-05-15
PE43995A1 (es) 1995-12-15
CO4600680A1 (es) 1998-05-08
DE10299053I2 (de) 2004-04-01
YU295A (sh) 1997-09-30
EP1087011A3 (en) 2002-02-06
LU90992I2 (fr) 2003-02-18
DK0662513T3 (da) 2001-05-28
JP3778588B2 (ja) 2006-05-24
RU2167936C2 (ru) 2001-05-27
ZA9514B (en) 1996-07-03
RU95100178A (ru) 1997-03-27
NO320157B1 (no) 2005-11-07
DE10299053I1 (de) 2003-05-22
HUT70465A (en) 1995-10-30
FI950044A0 (fi) 1995-01-04
NL300108I1 (nl) 2003-02-03
ES2156190T3 (es) 2001-06-16
PL180703B1 (pl) 2001-03-30
JPH07206704A (ja) 1995-08-08

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