FI941677A0 - NMR-kuvaukseen soveltuvia hiukkasia ja valmistusmenetelmä - Google Patents
NMR-kuvaukseen soveltuvia hiukkasia ja valmistusmenetelmäInfo
- Publication number
- FI941677A0 FI941677A0 FI941677A FI941677A FI941677A0 FI 941677 A0 FI941677 A0 FI 941677A0 FI 941677 A FI941677 A FI 941677A FI 941677 A FI941677 A FI 941677A FI 941677 A0 FI941677 A0 FI 941677A0
- Authority
- FI
- Finland
- Prior art keywords
- particles
- core
- glycerophospholipid
- micellar
- shell
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1806—Suspensions, emulsions, colloids, dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
- A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
- A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
- A61K49/1827—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
- A61K49/1833—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with a small organic molecule
- A61K49/1839—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with a small organic molecule the small organic molecule being a lipid, a fatty acid having 8 or more carbon atoms in the main chain, or a phospholipid
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/832—Nanostructure having specified property, e.g. lattice-constant, thermal expansion coefficient
- Y10S977/838—Magnetic property of nanomaterial
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/905—Specially adapted for travel through blood circulatory system
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/927—Diagnostic contrast agent
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/932—Specified use of nanostructure for electronic or optoelectronic application
- Y10S977/953—Detector using nanostructure
- Y10S977/96—Of magnetic property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
- Y10T428/2998—Coated including synthetic resin or polymer
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Nanotechnology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Radiology & Medical Imaging (AREA)
- Dispersion Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Oxygen, Ozone, And Oxides In General (AREA)
- Hard Magnetic Materials (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Soft Magnetic Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP92810618 | 1992-08-13 | ||
EP93810380 | 1993-05-25 | ||
PCT/EP1993/002046 WO1994004197A1 (en) | 1992-08-13 | 1993-07-30 | Particles for nmr imaging and method of manufacture |
Publications (2)
Publication Number | Publication Date |
---|---|
FI941677A0 true FI941677A0 (fi) | 1994-04-12 |
FI941677A FI941677A (fi) | 1994-04-12 |
Family
ID=26132520
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI941677A FI941677A (fi) | 1992-08-13 | 1994-04-12 | NMR-kuvaukseen soveltuvia hiukkasia ja valmistusmenetelmä |
Country Status (20)
Country | Link |
---|---|
US (3) | US5464696A (de) |
EP (1) | EP0607401B1 (de) |
JP (1) | JP2968588B2 (de) |
KR (1) | KR100307773B1 (de) |
CN (1) | CN1076205C (de) |
AT (1) | ATE144714T1 (de) |
AU (1) | AU660108B2 (de) |
CA (1) | CA2119654C (de) |
DE (1) | DE69305730T2 (de) |
DK (1) | DK0607401T3 (de) |
ES (1) | ES2094558T3 (de) |
FI (1) | FI941677A (de) |
GR (1) | GR3022288T3 (de) |
HU (1) | HU221805B1 (de) |
IL (1) | IL106493A (de) |
IS (1) | IS1648B (de) |
MX (1) | MX9304924A (de) |
NO (1) | NO307244B1 (de) |
NZ (1) | NZ254791A (de) |
WO (1) | WO1994004197A1 (de) |
Families Citing this family (51)
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TW319763B (de) | 1995-02-01 | 1997-11-11 | Epix Medical Inc | |
DE19508772C2 (de) * | 1995-03-01 | 1998-01-29 | Schering Ag | Verfahren und Verbindungen zur Detektion von Analyten mittels Remanenzmessung und deren Verwendung |
US8071737B2 (en) * | 1995-05-04 | 2011-12-06 | Glead Sciences, Inc. | Nucleic acid ligand complexes |
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DE19529921C2 (de) * | 1995-08-01 | 1997-09-25 | Schering Ag | Verwendung von MRT-Kontrastmitteln zur Ventilations-Bildgebung der Lunge |
JP4018141B2 (ja) * | 1995-11-01 | 2007-12-05 | ブラッコ・リサーチ・ソシエテ・アノニム | Nmr画像形成用の標的磁気標識分子マーカーシステム |
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ATE291439T1 (de) | 1996-01-10 | 2005-04-15 | Amersham Health As | Kontrastmittel |
AU7104598A (en) | 1997-04-09 | 1998-10-30 | Philipp Lang | New technique to monitor drug delivery noninvasively (in vivo) |
US6337215B1 (en) * | 1997-12-01 | 2002-01-08 | International Business Machines Corporation | Magnetic particles having two antiparallel ferromagnetic layers and attached affinity recognition molecules |
US6278893B1 (en) * | 1998-01-05 | 2001-08-21 | Nycomed Imaging As | Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent |
EP1118009A1 (de) * | 1998-09-28 | 2001-07-25 | Nycomed Imaging As | Verfahren der magnetresonanzbildgebung |
US6283448B1 (en) * | 2000-04-19 | 2001-09-04 | Daniel Webster Denton | Offset butterfly valve |
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US20050059031A1 (en) * | 2000-10-06 | 2005-03-17 | Quantum Dot Corporation | Method for enhancing transport of semiconductor nanocrystals across biological membranes |
ATE536550T1 (de) * | 2000-10-06 | 2011-12-15 | Life Technologies Corp | Halbleiter nanokristalle enthaltende transfektibare mizellen |
US20090060992A1 (en) * | 2002-05-08 | 2009-03-05 | University Of Central Florida Research Foundation, Inc., | Preparation of magneto-vesicles with DOPE/DDAB layers |
US9364569B2 (en) | 2003-02-04 | 2016-06-14 | Bracco Suisse S.A. | Ultrasound contrast agents and process for the preparation thereof |
US20070128117A1 (en) * | 2003-02-04 | 2007-06-07 | Bracco International B.V. | Ultrasound contrast agents and process for the preparation thereof |
DE10331439B3 (de) * | 2003-07-10 | 2005-02-03 | Micromod Partikeltechnologie Gmbh | Magnetische Nanopartikel mit verbesserten Magneteigenschaften |
WO2005063306A1 (en) * | 2003-12-22 | 2005-07-14 | Bracco Research Sa | Assembly of gas-filled microvesicle with active component for contrast imaging |
CA2547024C (en) * | 2003-12-22 | 2013-12-17 | Bracco Research Sa | Gas-filled microvesicle assembly for contrast imaging |
US20050260137A1 (en) * | 2004-05-18 | 2005-11-24 | General Electric Company | Contrast agents for magnetic resonance imaging |
US7229690B2 (en) * | 2004-07-26 | 2007-06-12 | Massachusetts Institute Of Technology | Microspheres including nanoparticles |
WO2006018433A1 (en) | 2004-08-18 | 2006-02-23 | Bracco Research Sa | Gas-filled microvesicles composition for contrast imaging |
US20080019918A1 (en) * | 2004-09-10 | 2008-01-24 | Takao Aoki | Medicinal Preparation |
US20070264199A1 (en) * | 2005-09-26 | 2007-11-15 | Labhasetwar Vinod D | Magnetic nanoparticle composition and methods for using the same |
US8361494B2 (en) * | 2006-03-10 | 2013-01-29 | The Trustees Of The University Of Pennsylvania | Biomimetic iron-oxide-containing lipoprotein and related materials |
US9446156B2 (en) | 2006-09-05 | 2016-09-20 | Bracco Suisse S.A. | Gas-filled microvesicles with polymer-modified lipids |
AU2007336297B2 (en) | 2006-12-18 | 2013-09-05 | Colorobbia Italia S.P.A. | Magnetic nanoparticles for the application in hyperthermia, preparation thereof and use in constructs having a pharmacological application |
US8784659B2 (en) * | 2007-08-08 | 2014-07-22 | General Electric Company | Method for controlling microbial biofilm in aqueous systems |
WO2009145813A1 (en) * | 2008-03-04 | 2009-12-03 | Qd Vision, Inc. | Particles including nanoparticles, uses thereof, and methods |
FR2934953B1 (fr) * | 2008-08-14 | 2011-01-21 | Commissariat Energie Atomique | Nanoemulsions de nanocristaux |
FR2934954B1 (fr) | 2008-08-14 | 2011-07-22 | Commissariat Energie Atomique | Emulsion fluorescente de vert d'indocyanine |
FR2934955B1 (fr) | 2008-08-14 | 2011-07-08 | Commissariat Energie Atomique | Encapsulation d'agents therapeutiques lipophiles ou amphiphiles dans des nanoemulsions |
EP2346532B1 (de) * | 2008-10-07 | 2020-10-07 | Bracco Suisse SA | Target-konstrukt mit einem anti-polymer-antikörper und an diesen bindende mikrovesikel |
WO2011031876A1 (en) | 2009-09-09 | 2011-03-17 | Qd Vision, Inc. | Formulations including nanoparticles |
WO2011031871A1 (en) | 2009-09-09 | 2011-03-17 | Qd Vision, Inc. | Particles including nanoparticles, uses thereof, and methods |
JP5678565B2 (ja) * | 2009-12-08 | 2015-03-04 | Jnc株式会社 | 磁性微粒子およびその製造方法 |
US20110217379A1 (en) * | 2010-03-08 | 2011-09-08 | Davis Llp | Magnetic nanomaterials and methods for chemoembolisation |
KR101174470B1 (ko) | 2010-04-08 | 2012-08-16 | 한국세라믹기술원 | 자성 실리카 리포좀 나노입자 및 이의 제조방법 |
TWI428284B (zh) | 2010-11-05 | 2014-03-01 | Nat Univ Chung Cheng | Sea urchin iron oxide and its manufacturing method |
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US8889103B2 (en) | 2010-12-15 | 2014-11-18 | General Electric Company | Diagnostic agent composition and associated methods thereof |
WO2012136813A2 (en) | 2011-04-07 | 2012-10-11 | Universitetet I Oslo | Agents for medical radar diagnosis |
EP2934740B1 (de) | 2012-12-21 | 2019-12-11 | Bracco Suisse SA | Gasgefüllte mikrovesikel |
WO2016191549A1 (en) * | 2015-05-26 | 2016-12-01 | Intezyne Technologies | Iron stabilized micelles as magnetic contrast agents |
FR3103376B1 (fr) * | 2019-11-26 | 2021-11-12 | Univ Bordeaux | Ferrofluide huileux biocompatible et procédé de préparation |
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BR112012010988B1 (pt) * | 2009-11-10 | 2019-06-18 | Microphyt | Reator fotossintético adaptado para a cultura de microrganismos fotossintéticos, particularmente algas,invólucro de reação para o mesmo, método para cultura demicrorganismos fotossintéticos, particularmente algas e método para a manufatura de um invólucro de reação |
-
1993
- 1993-07-26 US US08/096,414 patent/US5464696A/en not_active Expired - Lifetime
- 1993-07-27 IL IL10649393A patent/IL106493A/xx not_active IP Right Cessation
- 1993-07-27 IS IS4058A patent/IS1648B/is unknown
- 1993-07-30 DE DE69305730T patent/DE69305730T2/de not_active Expired - Lifetime
- 1993-07-30 ES ES93917714T patent/ES2094558T3/es not_active Expired - Lifetime
- 1993-07-30 JP JP6505830A patent/JP2968588B2/ja not_active Expired - Fee Related
- 1993-07-30 DK DK93917714.3T patent/DK0607401T3/da active
- 1993-07-30 HU HU9401038A patent/HU221805B1/hu not_active IP Right Cessation
- 1993-07-30 WO PCT/EP1993/002046 patent/WO1994004197A1/en active IP Right Grant
- 1993-07-30 AT AT93917714T patent/ATE144714T1/de not_active IP Right Cessation
- 1993-07-30 NZ NZ254791A patent/NZ254791A/en unknown
- 1993-07-30 KR KR1019940701200A patent/KR100307773B1/ko not_active IP Right Cessation
- 1993-07-30 EP EP93917714A patent/EP0607401B1/de not_active Expired - Lifetime
- 1993-07-30 AU AU47054/93A patent/AU660108B2/en not_active Ceased
- 1993-07-30 CA CA002119654A patent/CA2119654C/en not_active Expired - Fee Related
- 1993-08-12 CN CN93116505A patent/CN1076205C/zh not_active Expired - Fee Related
- 1993-08-13 MX MX9304924A patent/MX9304924A/es unknown
-
1994
- 1994-04-12 FI FI941677A patent/FI941677A/fi unknown
- 1994-04-12 NO NO941311A patent/NO307244B1/no not_active IP Right Cessation
-
1995
- 1995-04-13 US US08/421,330 patent/US5545395A/en not_active Expired - Lifetime
- 1995-04-13 US US08/421,329 patent/US5587199A/en not_active Expired - Lifetime
-
1997
- 1997-01-16 GR GR960403292T patent/GR3022288T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
IS4058A (is) | 1994-02-14 |
EP0607401B1 (de) | 1996-10-30 |
CN1089470A (zh) | 1994-07-20 |
US5545395A (en) | 1996-08-13 |
NO307244B1 (no) | 2000-03-06 |
MX9304924A (es) | 1994-08-31 |
DE69305730T2 (de) | 1997-05-28 |
NO941311L (no) | 1994-04-12 |
HUT75149A (en) | 1997-04-28 |
NO941311D0 (no) | 1994-04-12 |
HU221805B1 (hu) | 2003-01-28 |
NZ254791A (en) | 1996-11-26 |
HU9401038D0 (en) | 1994-07-28 |
JP2968588B2 (ja) | 1999-10-25 |
US5464696A (en) | 1995-11-07 |
JPH07503976A (ja) | 1995-04-27 |
IS1648B (is) | 1997-03-25 |
AU4705493A (en) | 1994-03-15 |
CA2119654A1 (en) | 1994-03-03 |
WO1994004197A1 (en) | 1994-03-03 |
AU660108B2 (en) | 1995-06-08 |
ATE144714T1 (de) | 1996-11-15 |
EP0607401A1 (de) | 1994-07-27 |
CA2119654C (en) | 2001-02-06 |
US5587199A (en) | 1996-12-24 |
CN1076205C (zh) | 2001-12-19 |
IL106493A0 (en) | 1993-11-15 |
ES2094558T3 (es) | 1997-01-16 |
DK0607401T3 (da) | 1996-11-25 |
IL106493A (en) | 1997-02-18 |
GR3022288T3 (en) | 1997-04-30 |
KR100307773B1 (ko) | 2001-12-28 |
FI941677A (fi) | 1994-04-12 |
DE69305730D1 (de) | 1996-12-05 |
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