IS4058A - Innsprautanleg vatnskennd sviflausn gagnleg sem langvarandi blóðkerfis NMR eftirmyndunar skuggaefni, agnir til notkunar í lausninni, aðferð til framleiðslu þeirra og notkunar - Google Patents

Innsprautanleg vatnskennd sviflausn gagnleg sem langvarandi blóðkerfis NMR eftirmyndunar skuggaefni, agnir til notkunar í lausninni, aðferð til framleiðslu þeirra og notkunar

Info

Publication number
IS4058A
IS4058A IS4058A IS4058A IS4058A IS 4058 A IS4058 A IS 4058A IS 4058 A IS4058 A IS 4058A IS 4058 A IS4058 A IS 4058A IS 4058 A IS4058 A IS 4058A
Authority
IS
Iceland
Prior art keywords
particles
core
replicating
preparation
solution
Prior art date
Application number
IS4058A
Other languages
English (en)
Other versions
IS1648B (is
Inventor
Tournier Hervé
Hyacinthe Roland
Schneider Michel
Original Assignee
Bracco International B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco International B.V. filed Critical Bracco International B.V.
Publication of IS4058A publication Critical patent/IS4058A/is
Publication of IS1648B publication Critical patent/IS1648B/is

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
    • A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
    • A61K49/1827—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
    • A61K49/1833—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with a small organic molecule
    • A61K49/1839—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with a small organic molecule the small organic molecule being a lipid, a fatty acid having 8 or more carbon atoms in the main chain, or a phospholipid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/832—Nanostructure having specified property, e.g. lattice-constant, thermal expansion coefficient
    • Y10S977/838—Magnetic property of nanomaterial
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/905—Specially adapted for travel through blood circulatory system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/927—Diagnostic contrast agent
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/932—Specified use of nanostructure for electronic or optoelectronic application
    • Y10S977/953—Detector using nanostructure
    • Y10S977/96—Of magnetic property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2998—Coated including synthetic resin or polymer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Nanotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Oxygen, Ozone, And Oxides In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Hard Magnetic Materials (AREA)
  • Soft Magnetic Materials (AREA)
IS4058A 1992-08-13 1993-07-27 Innsprautanleg vatnskennd sviflausn gagnleg sem langvarandi blóðkerfis NMR eftirmyndunar skuggaefni, agnir til notkunar í lausninni, aðferð til framleiðslu þeirra og notkunar IS1648B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP92810618 1992-08-13
EP93810380 1993-05-25

Publications (2)

Publication Number Publication Date
IS4058A true IS4058A (is) 1994-02-14
IS1648B IS1648B (is) 1997-03-25

Family

ID=26132520

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4058A IS1648B (is) 1992-08-13 1993-07-27 Innsprautanleg vatnskennd sviflausn gagnleg sem langvarandi blóðkerfis NMR eftirmyndunar skuggaefni, agnir til notkunar í lausninni, aðferð til framleiðslu þeirra og notkunar

Country Status (20)

Country Link
US (3) US5464696A (is)
EP (1) EP0607401B1 (is)
JP (1) JP2968588B2 (is)
KR (1) KR100307773B1 (is)
CN (1) CN1076205C (is)
AT (1) ATE144714T1 (is)
AU (1) AU660108B2 (is)
CA (1) CA2119654C (is)
DE (1) DE69305730T2 (is)
DK (1) DK0607401T3 (is)
ES (1) ES2094558T3 (is)
FI (1) FI941677A0 (is)
GR (1) GR3022288T3 (is)
HU (1) HU221805B1 (is)
IL (1) IL106493A (is)
IS (1) IS1648B (is)
MX (1) MX9304924A (is)
NO (1) NO307244B1 (is)
NZ (1) NZ254791A (is)
WO (1) WO1994004197A1 (is)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465188B1 (en) * 1990-06-11 2002-10-15 Gilead Sciences, Inc. Nucleic acid ligand complexes
DE4428851C2 (de) * 1994-08-04 2000-05-04 Diagnostikforschung Inst Eisen enthaltende Nanopartikel, ihre Herstellung und Anwendung in der Diagnostik und Therapie
US5520904A (en) * 1995-01-27 1996-05-28 Mallinckrodt Medical, Inc. Calcium/oxyanion-containing particles with a polymerical alkoxy coating for use in medical diagnostic imaging
TW319763B (is) * 1995-02-01 1997-11-11 Epix Medical Inc
DE19508772C2 (de) * 1995-03-01 1998-01-29 Schering Ag Verfahren und Verbindungen zur Detektion von Analyten mittels Remanenzmessung und deren Verwendung
US8071737B2 (en) * 1995-05-04 2011-12-06 Glead Sciences, Inc. Nucleic acid ligand complexes
US5833948A (en) * 1995-06-15 1998-11-10 Bracco Research S.A. Blood-pool imaging composition comprising micelles containing a lipophilic chelating agent and a non-ionic surfactant
DE19529921C2 (de) * 1995-08-01 1997-09-25 Schering Ag Verwendung von MRT-Kontrastmitteln zur Ventilations-Bildgebung der Lunge
JP4018141B2 (ja) * 1995-11-01 2007-12-05 ブラッコ・リサーチ・ソシエテ・アノニム Ｎｍｒ画像形成用の標的磁気標識分子マーカーシステム
EA001336B1 (ru) 1996-01-10 2001-02-26 Никомед Имеджинг Ас Контрастное вещество
GB9600427D0 (en) * 1996-01-10 1996-03-13 Nycomed Imaging As Contrast media
WO1998044910A1 (en) 1997-04-09 1998-10-15 Philipp Lang NEW TECHNIQUE TO MONITOR DRUG DELIVERY NONINVASIVELY $i(IN VIVO)
US6337215B1 (en) 1997-12-01 2002-01-08 International Business Machines Corporation Magnetic particles having two antiparallel ferromagnetic layers and attached affinity recognition molecules
US6278893B1 (en) * 1998-01-05 2001-08-21 Nycomed Imaging As Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent
EP1118009A1 (en) * 1998-09-28 2001-07-25 Nycomed Imaging As Method of magnetic resonance imaging
US6283448B1 (en) * 2000-04-19 2001-09-04 Daniel Webster Denton Offset butterfly valve
EP2279757A3 (en) 2000-06-02 2011-08-03 Bracco Suisse SA Compounds for targeting endothelial cells
US20050059031A1 (en) * 2000-10-06 2005-03-17 Quantum Dot Corporation Method for enhancing transport of semiconductor nanocrystals across biological membranes
WO2002029410A2 (en) * 2000-10-06 2002-04-11 Quantum Dot Corporation Cells having a spectral signature, and methods of preparation and use thereof
US20090060992A1 (en) * 2002-05-08 2009-03-05 University Of Central Florida Research Foundation, Inc., Preparation of magneto-vesicles with DOPE/DDAB layers
US20070128117A1 (en) * 2003-02-04 2007-06-07 Bracco International B.V. Ultrasound contrast agents and process for the preparation thereof
CA2512454C (en) 2003-02-04 2012-10-30 Bracco Research Sa Ultrasound contrast agents and process for the preparation thereof
DE10331439B3 (de) * 2003-07-10 2005-02-03 Micromod Partikeltechnologie Gmbh Magnetische Nanopartikel mit verbesserten Magneteigenschaften
CN100563718C (zh) * 2003-12-22 2009-12-02 伯拉考开发股份有限公司 用于反差成像的充气微囊组件
EP1696965B1 (en) * 2003-12-22 2014-12-10 Bracco Suisse SA Assembly of gas-filled microvesicle with active component for contrast imaging
US20050260137A1 (en) * 2004-05-18 2005-11-24 General Electric Company Contrast agents for magnetic resonance imaging
US7229690B2 (en) * 2004-07-26 2007-06-12 Massachusetts Institute Of Technology Microspheres including nanoparticles
CN103120799A (zh) 2004-08-18 2013-05-29 博莱科瑞士股份有限公司 用于反差成像的充气微泡组合物
US20080019918A1 (en) * 2004-09-10 2008-01-24 Takao Aoki Medicinal Preparation
US20070264199A1 (en) * 2005-09-26 2007-11-15 Labhasetwar Vinod D Magnetic nanoparticle composition and methods for using the same
WO2007106683A2 (en) * 2006-03-10 2007-09-20 The Trustees Of The University Of Pennsylvania Biomimetic iron-oxide-containing lipoprotein and related materials
AU2007293888B2 (en) 2006-09-05 2013-05-02 Bracco Suisse S.A. Gas-filled microvesicles with polymer-modified lipids
CA2672810C (en) * 2006-12-18 2015-06-02 Colorobbia Italia S.P.A. Magnetic nanoparticles for the application in hyperthermia, preparation thereof and use in constructs having a pharmacological application
US8784659B2 (en) * 2007-08-08 2014-07-22 General Electric Company Method for controlling microbial biofilm in aqueous systems
WO2009145813A1 (en) * 2008-03-04 2009-12-03 Qd Vision, Inc. Particles including nanoparticles, uses thereof, and methods
FR2934954B1 (fr) 2008-08-14 2011-07-22 Commissariat Energie Atomique Emulsion fluorescente de vert d'indocyanine
FR2934953B1 (fr) * 2008-08-14 2011-01-21 Commissariat Energie Atomique Nanoemulsions de nanocristaux
FR2934955B1 (fr) 2008-08-14 2011-07-08 Commissariat Energie Atomique Encapsulation d'agents therapeutiques lipophiles ou amphiphiles dans des nanoemulsions
EP2346532B1 (en) * 2008-10-07 2020-10-07 Bracco Suisse SA Targeting construct comprising anti-polymer antibody and microvesicles binding to the same
JP5744033B2 (ja) 2009-09-09 2015-07-01 キユーデイー・ビジヨン・インコーポレーテツド ナノ粒子を含む粒子、それの使用および方法
WO2011031876A1 (en) 2009-09-09 2011-03-17 Qd Vision, Inc. Formulations including nanoparticles
JP5678565B2 (ja) * 2009-12-08 2015-03-04 Jnc株式会社 磁性微粒子およびその製造方法
US20110217379A1 (en) * 2010-03-08 2011-09-08 Davis Llp Magnetic nanomaterials and methods for chemoembolisation
KR101174470B1 (ko) 2010-04-08 2012-08-16 한국세라믹기술원 자성 실리카 리포좀 나노입자 및 이의 제조방법
TWI428284B (zh) 2010-11-05 2014-03-01 Nat Univ Chung Cheng Sea urchin iron oxide and its manufacturing method
US8895068B2 (en) 2010-12-15 2014-11-25 General Electric Company Nanoparticle composition and associated methods thereof
US8889103B2 (en) 2010-12-15 2014-11-18 General Electric Company Diagnostic agent composition and associated methods thereof
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
US10010630B2 (en) 2012-12-21 2018-07-03 Bracco Suisse S.A. Gas-filled microvesicles
JP2018520113A (ja) * 2015-05-26 2018-07-26 インテザイン テクノロジーズ， インコーポレイテッド 磁性造影剤としての鉄安定化ミセル
FR3103376B1 (fr) * 2019-11-26 2021-11-12 Univ Bordeaux Ferrofluide huileux biocompatible et procédé de préparation

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4331654A (en) * 1980-06-13 1982-05-25 Eli Lilly And Company Magnetically-localizable, biodegradable lipid microspheres
US4331645A (en) * 1981-04-20 1982-05-25 Reynolds Metals Company Alumina from alkali metal-aluminum chloride complexes
NL194579C (nl) * 1983-01-21 2002-08-05 Schering Ag Diagnostisch middel.
JPS6072830A (ja) * 1983-09-29 1985-04-24 Kao Corp ベシクル用組成物
GB8408127D0 (en) * 1984-03-29 1984-05-10 Nyegaard & Co As Contrast agents
US4728575A (en) * 1984-04-27 1988-03-01 Vestar, Inc. Contrast agents for NMR imaging
DE3515373A1 (de) * 1985-04-27 1986-11-06 Merck Patent Gmbh, 6100 Darmstadt Stickstoffhaltige heterocyclen
US4675173A (en) * 1985-05-08 1987-06-23 Molecular Biosystems, Inc. Method of magnetic resonance imaging of the liver and spleen
JPS6295134A (ja) * 1985-10-21 1987-05-01 Nippon Saafuakutanto Kogyo Kk リポソ−ムの製造法
DE3619746A1 (de) * 1986-06-12 1987-12-17 Basf Ag Superparamagnetische feststoffteilchen
US5262176A (en) * 1986-07-03 1993-11-16 Advanced Magnetics, Inc. Synthesis of polysaccharide covered superparamagnetic oxide colloids
US4951675A (en) * 1986-07-03 1990-08-28 Advanced Magnetics, Incorporated Biodegradable superparamagnetic metal oxides as contrast agents for MR imaging
DK175531B1 (da) * 1986-12-15 2004-11-22 Nexstar Pharmaceuticals Inc Leveringsvehikel med amphiphil-associeret aktiv bestanddel
US5124289A (en) * 1986-12-29 1992-06-23 Aluminum Company Of America Surface treated permeable inorganic membranes and process of making same
US4994429A (en) * 1986-12-29 1991-02-19 Aluminum Company Of America Active material useful as adsorbent comprising metal oxide/hydroxide particles reacted with phosphorus-containing organic acid group of organic compound having unreacted acid group
US4929589A (en) * 1986-12-29 1990-05-29 Aluminum Company Of America Metal oxide/hydroxide particles coated with phosphate esters
US4983566A (en) * 1987-03-09 1991-01-08 Aluminum Company Of America Surface-modified adsorbent comprising metal oxide/hydroxide particles reacted with one or more perfluorinated organic acids
US5000960A (en) * 1987-03-13 1991-03-19 Micro-Pak, Inc. Protein coupling to lipid vesicles
DE3709851A1 (de) * 1987-03-24 1988-10-06 Silica Gel Gmbh Adsorptions Te Nmr-diagnostische fluessigkeitszusammensetzungen
JPH0720857B2 (ja) * 1988-08-11 1995-03-08 テルモ株式会社 リポソームおよびその製法
US5230882A (en) * 1989-12-22 1993-07-27 Unger Evan C Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same
GB9007052D0 (en) * 1990-03-29 1990-05-30 Skua Investments Ltd Pharmaceutical formulations
US5246707A (en) * 1990-04-26 1993-09-21 Haynes Duncan H Sustained release delivery of water-soluble bio-molecules and drugs using phospholipid-coated microcrystals, microdroplets and high-concentration liposomes
US5091188A (en) * 1990-04-26 1992-02-25 Haynes Duncan H Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
CA2046997C (en) * 1990-07-16 2000-12-12 Hiroshi Kikuchi Liposomal products
DE4100470A1 (de) * 1991-01-09 1992-07-16 Byk Gulden Lomberg Chem Fab Echokontrastmittel
JP3272736B2 (ja) * 1991-01-31 2002-04-08 協和醗酵工業株式会社 リポソーム製剤
CA2064683A1 (en) * 1992-03-26 1993-09-27 Krishna Mohan Rao Kallury Formation of thermostable enzymes with extra-ordinary heat tolerance by immobilization on phospholipid matrices
US5411730A (en) * 1993-07-20 1995-05-02 Research Corporation Technologies, Inc. Magnetic microparticles
US5494744A (en) * 1994-10-12 1996-02-27 Kimberly-Clark Corporation Method of applying a protein coating to a substrate and article thereof
WO2011058267A2 (fr) * 2009-11-10 2011-05-19 Microphyt Enveloppe de reaction pour un reacteur photosynthetique et reacteur photosynthetique associe

Also Published As

Publication number Publication date
AU4705493A (en) 1994-03-15
NO307244B1 (no) 2000-03-06
ES2094558T3 (es) 1997-01-16
CN1076205C (zh) 2001-12-19
FI941677A (fi) 1994-04-12
KR100307773B1 (ko) 2001-12-28
NO941311D0 (no) 1994-04-12
EP0607401B1 (en) 1996-10-30
IL106493A0 (en) 1993-11-15
IL106493A (en) 1997-02-18
HU221805B1 (hu) 2003-01-28
US5587199A (en) 1996-12-24
US5545395A (en) 1996-08-13
DK0607401T3 (da) 1996-11-25
CA2119654C (en) 2001-02-06
HU9401038D0 (en) 1994-07-28
WO1994004197A1 (en) 1994-03-03
NZ254791A (en) 1996-11-26
MX9304924A (es) 1994-08-31
IS1648B (is) 1997-03-25
JPH07503976A (ja) 1995-04-27
ATE144714T1 (de) 1996-11-15
DE69305730D1 (de) 1996-12-05
DE69305730T2 (de) 1997-05-28
CA2119654A1 (en) 1994-03-03
GR3022288T3 (en) 1997-04-30
HUT75149A (en) 1997-04-28
CN1089470A (zh) 1994-07-20
JP2968588B2 (ja) 1999-10-25
FI941677A0 (fi) 1994-04-12
NO941311L (no) 1994-04-12
EP0607401A1 (en) 1994-07-27
US5464696A (en) 1995-11-07
AU660108B2 (en) 1995-06-08

Similar Documents

Publication Publication Date Title
IS4058A (is) Innsprautanleg vatnskennd sviflausn gagnleg sem langvarandi blóðkerfis NMR eftirmyndunar skuggaefni, agnir til notkunar í lausninni, aðferð til framleiðslu þeirra og notkunar
CA1265721A (en) Free-flowing pearlescent concentrate
WO2000009531A3 (en) β-L-2'-DEOXY-NUCLEOSIDES FOR THE TREATMENT OF HEPATITIS B
ID22102A (id) Peralatan resonansi magnetik inti dan metode untuk menghasilkan medan magnet aksisimetri yang memiliki garis-garis keliling lurus di daerah resonansi tersebut
CA2401942A1 (en) Pharmaceutical compositions for buccal and pulmonary application
PT91523A (pt) Verfahren zur herstellung eines ultraschallkontrastmittels aus gasblaeschen und fettsaeure enthaltenden mikropartikeln
ZA971813B (en) Polymer-lipid microencapsulated gases for use as imaging agents.
HK1062024A1 (en) Polyurethane elastomers with improved hydrolysis stability
DE3168276D1 (en) Injectable composition of rapamycin
ATE191733T1 (de) Verminderung des beschlagens in polyurethanschaum mittels phosphatestern
DE69813310D1 (de) Verfahren zur Herstellung von Alkylenoxidaddukten aus Fettsäureestern einwertiger Alkohole und Alkylenoxiden
NO984555D0 (no) T1- Lever
DE50104555D1 (de) Verfahren zur herstellung von tert.-butylestern aliphatischer c1-c4-carbonsäuren
DE60138834D1 (de) Fettsäureanaloge zur behandlung von entzündungs- und autoimmunerkrankungen
Waltham et al. Association of ferri-and ferro-cytochrome c with lipid multilayers: a 31P solid-state NMR study
Bonucci et al. Histochemical properties of the “crystal ghosts” of calcifying epiphyseal cartilage
Levy et al. Apparent CP violation due to a new vector boson
Lapetina et al. The importance of the production of phosphatidic acid for the release of arachidonic acid in stimulated platelets
MY131202A (en) Accelerators for curing phenolic resole resins
KR950007836A (ko) 간세포를 표적할 수 있는 pH에 민감한 리포좀의 제조방법
SE9500759D0 (sv) Metod att avskärma den magnetiska delen i ett elektromagnetiskt fält
JPS63307709A (ja) 多極磁石集合体
WO2001031345A3 (de) Computerbasierte analyse der dreidimensionalen strukturen von glykoanteilen
DE50006815D1 (de) Verfahren zur herstellung antitumoraler th1-zellen