FI933065A7 - Menetelmä atsabisyklo(2.2.2)oktaani-3-imiinien valmistamiseksi ja menetelmässä käytetyt välituotteet - Google Patents

Menetelmä atsabisyklo(2.2.2)oktaani-3-imiinien valmistamiseksi ja menetelmässä käytetyt välituotteet Download PDF

Info

Publication number
FI933065A7
FI933065A7 FI933065A FI933065A FI933065A7 FI 933065 A7 FI933065 A7 FI 933065A7 FI 933065 A FI933065 A FI 933065A FI 933065 A FI933065 A FI 933065A FI 933065 A7 FI933065 A7 FI 933065A7
Authority
FI
Finland
Prior art keywords
azabicyclo
imines
octane
preparation
intermediates used
Prior art date
Application number
FI933065A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI933065L (fi
FI933065A0 (fi
Inventor
Dennis M Godek
Charles W Murtiashaw
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI933065L publication Critical patent/FI933065L/fi
Publication of FI933065A0 publication Critical patent/FI933065A0/fi
Publication of FI933065A7 publication Critical patent/FI933065A7/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Apparatuses For Bulk Treatment Of Fruits And Vegetables And Apparatuses For Preparing Feeds (AREA)
  • Indole Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI933065A 1991-01-03 1991-12-18 Menetelmä atsabisyklo(2.2.2)oktaani-3-imiinien valmistamiseksi ja menetelmässä käytetyt välituotteet FI933065A7 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/637,102 US5138060A (en) 1991-01-03 1991-01-03 Process and intermediates for preparing azabicyclo(2.2.2)octan-3-imines
PCT/US1991/009186 WO1992012152A1 (en) 1991-01-03 1991-12-18 Process and intermediates for preparing azabicyclo[2.2.2]octan-3-imines

Publications (3)

Publication Number Publication Date
FI933065L FI933065L (fi) 1993-07-02
FI933065A0 FI933065A0 (fi) 1993-07-02
FI933065A7 true FI933065A7 (fi) 1993-07-02

Family

ID=24554545

Family Applications (3)

Application Number Title Priority Date Filing Date
FI933065A FI933065A7 (fi) 1991-01-03 1991-12-18 Menetelmä atsabisyklo(2.2.2)oktaani-3-imiinien valmistamiseksi ja menetelmässä käytetyt välituotteet
FI20001108A FI20001108L (fi) 1991-01-03 2000-05-10 Menetelmä raseemisen cis-yhdisteen valmistamiseksi
FI20001109A FI20001109L (fi) 1991-01-03 2000-05-10 Menetelmä cis-yhdisteen raseemisen seoksen resolvoimiseksi

Family Applications After (2)

Application Number Title Priority Date Filing Date
FI20001108A FI20001108L (fi) 1991-01-03 2000-05-10 Menetelmä raseemisen cis-yhdisteen valmistamiseksi
FI20001109A FI20001109L (fi) 1991-01-03 2000-05-10 Menetelmä cis-yhdisteen raseemisen seoksen resolvoimiseksi

Country Status (21)

Country Link
US (1) US5138060A (enExample)
EP (1) EP0565558B1 (enExample)
JP (5) JPH0768244B2 (enExample)
KR (1) KR970001157B1 (enExample)
AT (1) ATE115580T1 (enExample)
AU (1) AU653380B2 (enExample)
CA (2) CA2098989C (enExample)
DE (1) DE69106003T2 (enExample)
DK (1) DK0565558T3 (enExample)
ES (1) ES2065161T3 (enExample)
FI (3) FI933065A7 (enExample)
GR (1) GR3015021T3 (enExample)
HU (1) HU9301931D0 (enExample)
IE (1) IE65005B1 (enExample)
IL (1) IL100541A0 (enExample)
MX (1) MX9200003A (enExample)
NO (1) NO932431L (enExample)
NZ (1) NZ241161A (enExample)
PT (1) PT99970B (enExample)
WO (1) WO1992012152A1 (enExample)
ZA (1) ZA928B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364943A (en) * 1991-11-27 1994-11-15 Pfizer Inc. Preparation of substituted piperidines
CA2109613C (en) * 1991-06-20 1996-11-19 John Adams Lowe Iii Fluoroalkoxybenzylamino derivatives of nitrogen containing heterocycles
CA2123403C (en) * 1991-11-12 2002-02-05 Brian T. O'neill Acyclic ethylenediamine derivatives as substance p receptor antagonists
ES2164657T3 (es) * 1992-05-18 2002-03-01 Pfizer Derivados aza-biciclicos puenteados como antagonistas de la sustancia p.
US5719147A (en) * 1992-06-29 1998-02-17 Merck & Co., Inc. Morpholine and thiomorpholine tachykinin receptor antagonists
US5637699A (en) * 1992-06-29 1997-06-10 Merck & Co., Inc. Process for preparing morpholine tachykinin receptor antagonists
US6048859A (en) * 1992-06-29 2000-04-11 Merck & Co., Inc. Morpholine and thiomorpholine tachykinin receptor antagonists
WO1994003445A1 (en) * 1992-08-04 1994-02-17 Pfizer Inc. 3-benzylamino-2-phenyl-piperidine derivatives as substance p receptor antagonists
US5387595A (en) * 1992-08-26 1995-02-07 Merck & Co., Inc. Alicyclic compounds as tachykinin receptor antagonists
US5518628A (en) * 1993-11-08 1996-05-21 Shipley Company Inc. Purification process
IL112778A0 (en) * 1994-03-04 1995-05-26 Merck & Co Inc Substituted heterocycles, their preparation and pharmaceutical compositions containing them
US6861526B2 (en) 2002-10-16 2005-03-01 Pfizer Inc. Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine
WO2005045395A2 (en) * 2003-10-27 2005-05-19 Meyer Donald W Method of detecting bovine spongiform encephalopathy

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3560510A (en) * 1969-03-05 1971-02-02 Aldrich Chem Co Inc 2-benzhydrylquinuclidines
US3993652A (en) * 1973-07-09 1976-11-23 Air Products And Chemicals, Inc. Cyclic quaternary hydroxyalkyl phenoxide catalysts for isocyanate reactions
US4203990A (en) * 1979-04-30 1980-05-20 G. D. Searle & Co. Anti-diarrheal 2-substituted quinuclidines
FR2529548A1 (fr) * 1982-07-02 1984-01-06 Delalande Sa Nouveaux derives de l'amino-3 quinuclidine, leur procede et leur application en therapeutique
JPS59110656A (ja) * 1982-12-15 1984-06-26 Hiroyuki Nohira 光学活性な１―フェニル―２―（パラ―トリル）エチルアミンの製造方法
DE3604591A1 (de) * 1986-02-14 1987-08-20 Degussa Verfahren zur herstellung chiraler glycinderivate
JPS6354342A (ja) * 1986-08-26 1988-03-08 Daicel Chem Ind Ltd （±）−α−エチルベンジルアミンの光学分割方法
JPS63145256A (ja) * 1986-12-09 1988-06-17 Nippon Kayaku Co Ltd 光学活性ホモフエニルアラニンの製造法及び中間体
MX18467A (es) * 1988-11-23 1993-07-01 Pfizer Agentes terapeuticos de quinuclidinas
CZ247993A3 (en) * 1991-05-22 1994-07-13 Pfizer Substituted 3-aminoquinuclidine derivatives, process of their preparation and use thereof

Also Published As

Publication number Publication date
ES2065161T3 (es) 1995-02-01
NO932431D0 (no) 1993-07-02
JPH0768244B2 (ja) 1995-07-26
FI933065L (fi) 1993-07-02
GR3015021T3 (en) 1995-05-31
EP0565558A1 (en) 1993-10-20
ATE115580T1 (de) 1994-12-15
AU9129891A (en) 1992-08-17
FI933065A0 (fi) 1993-07-02
KR930703312A (ko) 1993-11-29
JPH0768244B1 (enExample) 1995-07-26
FI20001109A7 (fi) 2000-05-10
CA2158130A1 (en) 1992-07-04
EP0565558B1 (en) 1994-12-14
FI20001108A7 (fi) 2000-05-10
JP2845425B2 (ja) 1999-01-13
HU9301931D0 (en) 1993-12-28
NO932431L (no) 1993-07-02
CA2098989A1 (en) 1992-07-04
CA2158130C (en) 1998-07-14
DK0565558T3 (da) 1995-03-06
IE65005B1 (en) 1995-10-04
US5138060A (en) 1992-08-11
JPH05508867A (ja) 1993-12-09
JP2583026B2 (ja) 1997-02-19
CA2098989C (en) 1998-02-03
NZ241161A (en) 1994-10-26
IL100541A0 (en) 1992-09-06
IE920001A1 (en) 1992-07-15
FI20001108L (fi) 2000-05-10
JP2703193B2 (ja) 1998-01-26
AU653380B2 (en) 1994-09-29
PT99970A (pt) 1993-02-26
DE69106003D1 (de) 1995-01-26
DE69106003T2 (de) 1995-04-27
JPH07316154A (ja) 1995-12-05
MX9200003A (es) 1992-07-01
KR970001157B1 (ko) 1997-01-29
ZA928B (en) 1993-07-02
WO1992012152A1 (en) 1992-07-23
JPH07316153A (ja) 1995-12-05
JPH07330766A (ja) 1995-12-19
FI20001109L (fi) 2000-05-10
PT99970B (pt) 1999-06-30

Similar Documents

Publication Publication Date Title
FI943207A0 (fi) 4,5-dihydrogeldanamysiinin ja sen hydrokinonin valmistusmenetelmä ja käyttö
FI952179A7 (fi) Uusia 3,3-difenyylipropyyliamiineja, niiden käyttö ja valmistus
KR950701061A (ko) 방탄제품 및 이의 제조방법(Ballistic-resistane articlt and process for making the same)
FI921875A7 (fi) Menetelmä lääkeaineina käyttökelpoisten bentsisotiatsoli- ja bentsisoksatsoli-3-karboksiamidien valmistamiseksi
EP0458333A3 (en) Polyisocyanato-isocyanurate, and preparation process and use of the same
MX9203099A (es) N-heterociclico-n-(4-piperidia)amidas y composiciones farmaceuticas y metodos que emplean dichos compuestos.
FI912296A7 (fi) Menetelmä 1,1,1,2-tetrafluorikloorietaanin ja pentafluorietaanin valmistamiseksi
FI971268A7 (fi) Menetelmä 1,3-alkaanidiolien ja 3-hydroksialdehydien valmistamiseksi
FI880453A7 (fi) Nukutusainekoostumus ja menetelmä sen käyttämiseksi.
FI933065A7 (fi) Menetelmä atsabisyklo(2.2.2)oktaani-3-imiinien valmistamiseksi ja menetelmässä käytetyt välituotteet
FI921284A7 (fi) Jäykkien vaahtojen valmistus ja siinä käytettävä koostumus
NO913686L (no) Fremgangsmaate for fremstilling av 9-substituerte guaninderivater og mellomprodukter for anvendelse i fremgangsmaaten.
FI894546A7 (fi) Menetelmä uusien 2'-halogeenimetylideeni-, 2'-etenylideeni- ja 2'-etynyyliadenosiinijohdannaisten valmistamiseksi
FI875684A7 (fi) 1,1,2,2-tetrahydroperfluorialkanolien ja niiden estereiden valmistusmenetelmä.
DE69220708D1 (de) Verfahren zur Herstellung von 2,2,6,6,-Tetramethyl-4-Amino-Piperidilen
FI971267L (fi) Menetelmä 1,3-alkaanidiolien ja 3-hydroksialdehydien valmistamiseksi
FI924053A7 (fi) Substituoidut aminopropaanit, menetelmä niiden valmistamiseksi ja niiden käyttö
FI925111A7 (fi) Substituoidut 1,5-pentaanidiolit ja menetelmä niiden valmistamiseksi
NO903347D0 (no) Fremgangsmaate for fremstilling av 14,17alfa-ethano- og ethanooestratriener.
FI972530L (fi) Menetelmä substituoitujen 4-etyyli-piperidiinien valmistamiseksi ja niiden valmistuksessa käytettävä välituote
FI930238A7 (fi) N-5-suojatut 2,5-diamino-4,6-diklooripyrimidiinit ja menetelmä niiden valmistamiseksi
FI943213A7 (fi) Prosessi valmistaa 3-asyyliestratrieenejä ja asyylibentseenejä
NO921086D0 (no) Fremgangsmaate for fremstilling og anvendelse av substituerte 2',3'-didesoksy-5-trifluormetyluridiner
FI915025A7 (fi) 8-atsabisyklo(3,2,1)oktyylialkyylitiatsolidinoneja, menetelmä niiden valmistamiseksi ja niiden käyttö lääkeaineina
FI875685A7 (fi) 1,1,2,2-tetrahydroperfluorialkanolien ja niiden estereiden valmistusmenetelmä.

Legal Events

Date Code Title Description
FD Application lapsed