DK0565558T3 - Fremgangsmåde og mellemprodukter til fremstilling af azabicyclo(2.2.2)octan-3-iminer - Google Patents

Fremgangsmåde og mellemprodukter til fremstilling af azabicyclo(2.2.2)octan-3-iminer

Info

Publication number
DK0565558T3
DK0565558T3 DK92901603.8T DK92901603T DK0565558T3 DK 0565558 T3 DK0565558 T3 DK 0565558T3 DK 92901603 T DK92901603 T DK 92901603T DK 0565558 T3 DK0565558 T3 DK 0565558T3
Authority
DK
Denmark
Prior art keywords
octan
azabicyclo
imines
intermediates
preparation
Prior art date
Application number
DK92901603.8T
Other languages
English (en)
Inventor
Dennis M Godek
Charles W Murtiashaw
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0565558T3 publication Critical patent/DK0565558T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Apparatuses For Bulk Treatment Of Fruits And Vegetables And Apparatuses For Preparing Feeds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Indole Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DK92901603.8T 1991-01-03 1991-12-18 Fremgangsmåde og mellemprodukter til fremstilling af azabicyclo(2.2.2)octan-3-iminer DK0565558T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/637,102 US5138060A (en) 1991-01-03 1991-01-03 Process and intermediates for preparing azabicyclo(2.2.2)octan-3-imines

Publications (1)

Publication Number Publication Date
DK0565558T3 true DK0565558T3 (da) 1995-03-06

Family

ID=24554545

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92901603.8T DK0565558T3 (da) 1991-01-03 1991-12-18 Fremgangsmåde og mellemprodukter til fremstilling af azabicyclo(2.2.2)octan-3-iminer

Country Status (21)

Country Link
US (1) US5138060A (da)
EP (1) EP0565558B1 (da)
JP (5) JPH0768244B1 (da)
KR (1) KR970001157B1 (da)
AT (1) ATE115580T1 (da)
AU (1) AU653380B2 (da)
CA (2) CA2098989C (da)
DE (1) DE69106003T2 (da)
DK (1) DK0565558T3 (da)
ES (1) ES2065161T3 (da)
FI (3) FI933065A (da)
GR (1) GR3015021T3 (da)
HU (1) HU9301931D0 (da)
IE (1) IE65005B1 (da)
IL (1) IL100541A0 (da)
MX (1) MX9200003A (da)
NO (1) NO932431D0 (da)
NZ (1) NZ241161A (da)
PT (1) PT99970B (da)
WO (1) WO1992012152A1 (da)
ZA (1) ZA928B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364943A (en) * 1991-11-27 1994-11-15 Pfizer Inc. Preparation of substituted piperidines
ES2092113T3 (es) * 1991-06-20 1996-11-16 Pfizer Derivados fluoroalcoxibencilamino de heterociclos que contienen nitrogeno.
CA2324959C (en) * 1991-11-12 2002-11-12 Pfizer Limited Phthalimido compounds as intermediates for producing substance p receptor antagonists
CA2134964C (en) * 1992-05-18 1997-12-30 Manoj C. Desai Bridged aza-bicyclic derivatives as substance p antagonists
US5637699A (en) * 1992-06-29 1997-06-10 Merck & Co., Inc. Process for preparing morpholine tachykinin receptor antagonists
US5719147A (en) * 1992-06-29 1998-02-17 Merck & Co., Inc. Morpholine and thiomorpholine tachykinin receptor antagonists
US6048859A (en) 1992-06-29 2000-04-11 Merck & Co., Inc. Morpholine and thiomorpholine tachykinin receptor antagonists
CA2141051A1 (en) * 1992-08-04 1994-02-17 Terry J. Rosen Substituted nitrogen-containing heterocycles
US5387595A (en) * 1992-08-26 1995-02-07 Merck & Co., Inc. Alicyclic compounds as tachykinin receptor antagonists
US5518628A (en) * 1993-11-08 1996-05-21 Shipley Company Inc. Purification process
TW385308B (en) * 1994-03-04 2000-03-21 Merck & Co Inc Prodrugs of morpholine tachykinin receptor antagonists
US6861526B2 (en) 2002-10-16 2005-03-01 Pfizer Inc. Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine
WO2005043153A1 (en) * 2003-10-27 2005-05-12 Meyer Donald W Transmissible spongiform encephalopathy detection in cervids, sheep and goats

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3560510A (en) * 1969-03-05 1971-02-02 Aldrich Chem Co Inc 2-benzhydrylquinuclidines
US3993652A (en) * 1973-07-09 1976-11-23 Air Products And Chemicals, Inc. Cyclic quaternary hydroxyalkyl phenoxide catalysts for isocyanate reactions
US4203990A (en) * 1979-04-30 1980-05-20 G. D. Searle & Co. Anti-diarrheal 2-substituted quinuclidines
FR2529548A1 (fr) * 1982-07-02 1984-01-06 Delalande Sa Nouveaux derives de l'amino-3 quinuclidine, leur procede et leur application en therapeutique
JPS59110656A (ja) * 1982-12-15 1984-06-26 Hiroyuki Nohira 光学活性な１―フェニル―２―（パラ―トリル）エチルアミンの製造方法
DE3604591A1 (de) * 1986-02-14 1987-08-20 Degussa Verfahren zur herstellung chiraler glycinderivate
JPS6354342A (ja) * 1986-08-26 1988-03-08 Daicel Chem Ind Ltd （±）−α−エチルベンジルアミンの光学分割方法
JPS63145256A (ja) * 1986-12-09 1988-06-17 Nippon Kayaku Co Ltd 光学活性ホモフエニルアラニンの製造法及び中間体
WO1990005525A1 (en) * 1988-11-23 1990-05-31 Pfizer Inc. Quinuclidine derivatives as substance p antagonists
DE9290057U1 (de) * 1991-05-22 1994-01-05 Pfizer Substituierte 3-Aminochinuclidine

Also Published As

Publication number Publication date
JPH07316154A (ja) 1995-12-05
NO932431L (no) 1993-07-02
JPH0768244B1 (da) 1995-07-26
US5138060A (en) 1992-08-11
PT99970B (pt) 1999-06-30
AU653380B2 (en) 1994-09-29
FI933065A0 (fi) 1993-07-02
FI20001108A (fi) 2000-05-10
JPH07330766A (ja) 1995-12-19
JP2583026B2 (ja) 1997-02-19
JP2703193B2 (ja) 1998-01-26
KR930703312A (ko) 1993-11-29
CA2158130C (en) 1998-07-14
CA2098989C (en) 1998-02-03
DE69106003D1 (de) 1995-01-26
NO932431D0 (no) 1993-07-02
JP2845425B2 (ja) 1999-01-13
FI20001109A (fi) 2000-05-10
HU9301931D0 (en) 1993-12-28
EP0565558B1 (en) 1994-12-14
IL100541A0 (en) 1992-09-06
CA2158130A1 (en) 1992-07-04
WO1992012152A1 (en) 1992-07-23
KR970001157B1 (ko) 1997-01-29
EP0565558A1 (en) 1993-10-20
ZA928B (en) 1993-07-02
AU9129891A (en) 1992-08-17
DE69106003T2 (de) 1995-04-27
IE65005B1 (en) 1995-10-04
CA2098989A1 (en) 1992-07-04
ATE115580T1 (de) 1994-12-15
IE920001A1 (en) 1992-07-15
FI933065A (fi) 1993-07-02
NZ241161A (en) 1994-10-26
ES2065161T3 (es) 1995-02-01
GR3015021T3 (en) 1995-05-31
PT99970A (pt) 1993-02-26
MX9200003A (es) 1992-07-01
JPH05508867A (ja) 1993-12-09
JPH07316153A (ja) 1995-12-05

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